ライフサイエンスコーパス: dissociation inhibitor

1 her on membranes or in cytosol, bound to GDP dissociation inhibitor.

2 Ig-like domain of the Rho guanine nucleotide dissociation inhibitor.

3 interaction with the Rho guanine nucleotide dissociation inhibitor.

4 ng protein and ARF domains, may act as a GDP dissociation inhibitor.

5 is a highly conserved Ran guanine nucleotide dissociation inhibitor.

6 d through Rdi1, the Cdc42 guanine nucleotide dissociation inhibitor.

7 1-20 membranes remained sensitive to Rab GDP dissociation inhibitor.

8 ion of Galphai, acting as guanine nucleotide dissociation inhibitors.

9 ultured cells is not associated with Rab GDP dissociation inhibitors.

10 inal domains of the guanosine 5'-diphosphate dissociation inhibitors.

11 lation of Rab1 disrupts interaction with GDP dissociation inhibitor 1 (GDI1), but not guanine exchang

12 8 integrin coimmunoprecipitates with Rho-GDP dissociation inhibitor 1 (RhoGDI1), an intracellular sig

13 ily GTPase regulator, Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1), can interact with ep

14 zation and phosphorylation status of Rho GDP dissociation inhibitor 1 (RhoGDI1).

15 eta8 interaction with Rho guanine nucleotide dissociation inhibitor-1 (GDI).

16 Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identified a

17 A reduction in Rho GDP Dissociation Inhibitor 2 (RhoGDI2) protein has been asso

18 hibitor of Rho proteins known as the Rho-GDP dissociation inhibitor 2 (RhoGDI2).

19 Low expression of RhoGTP dissociation inhibitor 2 (RhoGDI2; also known as ARHGDIB

20 Rho1-GDP in vitro and that Msb3 and Rho GDP dissociation inhibitor act independently but oppositely

21 -amino-acid sequence with guanine nucleotide dissociation inhibitor activity against G-alpha subunits

22 s through its two GoLoco motifs to exert GDP dissociation inhibitor activity over Galpha(i) subunits;

23 g domains, and a GoLoco motif, which has GDP dissociation inhibitor activity.

24 Previous studies revealed that Rho GDP-dissociation inhibitor alpha (RhoGDIalpha) is involved i

25 cell survival and proliferation, and Rho GDP dissociation inhibitor alpha (RhoGDIalpha), a member of

26 ycle regulated by the Rho guanine nucleotide dissociation inhibitor alpha (RhoGDIalpha).

27 subunit/DJ-1 PARK7) and RhoGDIalpha (Rho GDP-dissociation inhibitor alpha).

28 The Rab-specific alphaGDP-dissociation inhibitor (alphaGDI) regulates the recyclin

29 es suggest that PCP2 is a guanine nucleotide dissociation inhibitor, although a guanine nucleotide ex

30 2 (PCP2), a member of the family of guanine dissociation inhibitors and a strong interactor with the

31 of Gbetagamma signaling pathways, act as GDP dissociation inhibitors and negatively regulate the acti

32 between RhoA and Rho-GDI (guanine nucleotide dissociation inhibitor) and promotes the membrane transl

33 in signaling 3 (AGS3, its guanine nucleotide dissociation inhibitor), and GIV determines whether auto

34 substrates poly(ADP-ribose) polymerase, GDP dissociation inhibitor, and PKCdelta was observed when P

35 factors (GEF); group II, guanine nucleotide dissociation inhibitors; and group III, entities that bi

36 ion inhibitors Nme1, Nme2, and Nme3, the GDP dissociation inhibitor Arhgdib, and the metalloprotease

37 itro but promoted binding to the Rho guanine-dissociation inhibitor as measured by exchange factor co

38 DPC localization of CD43 and RhoGDP dissociation inhibitor, as well as the novel DPC protein

39 ncluding beta-lactate dehydrogenase, Rho GDP dissociation inhibitor beta, ATP synthase, elongation fa

40 RC1), by its direct association with Rab GDP dissociation inhibitor beta, which likely regulates RHEB

41 and functions as a Gsp1p guanine nucleotide dissociation inhibitor by reducing the activity of Prp20

42 inding proteins of the rab family by rab GDP dissociation inhibitor completely abolishes formation of

43 The Rho GDP dissociation inhibitor D4-GDI is overexpressed in some h

44 ibition of Pak1 kinase activity and Rac1-GDP-dissociation inhibitor disassociation, and inhibition of

45 membranes functions as a guanine nucleotide dissociation inhibitor displacement factor.

46 PR peptide functions as a guanine nucleotide dissociation inhibitor for Gialpha.

47 Galpha(GDP) and acts as a guanine nucleotide dissociation inhibitor for heterotrimeric G-proteins.

48 osol, and this effect was blocked by the GDP dissociation inhibitor for Rho (Rho-GDI).

49 ing Rho GDIalpha, an endogenous specific GDP dissociation inhibitor for Rho family proteins, using th

50 d by expressing Rho GDIalpha, a specific GDP dissociation inhibitor for Rho family proteins, using th

51 t D4-GDI, an abundant hematopoietic cell GDP dissociation inhibitor for the Ras-related Rho family GT

52 poly(ADP ribose) polymerase and D4-GDI (GDP dissociation inhibitor for the rho family), as well as t

53 RhoGDI, a guanine-nucleotide dissociation inhibitor for the Rho family, inhibits phos

54 ins as nucleotide exchange factors or as GDP dissociation inhibitors for Galpha have been proposed.

55 lts suggest that GPR proteins are potent GDP dissociation inhibitors for Gialpha-like Galpha subunits

56 i.e. G betagamma, AGS3 (a guanine nucleotide dissociation inhibitor), GAIP/RGS19 (a GTPase-activating

57 i) signals because of the guanine nucleotide dissociation inhibitor (GDI) activity of a GoLoco motif

58 ays, both regions exhibit guanine nucleotide dissociation inhibitor (GDI) activity, inhibiting the ra

59 unctionally mimics a host guanine nucleotide dissociation inhibitor (GDI) by contacting key residues

60 are kept soluble in the cytoplasm by the GDP dissociation inhibitor (GDI) chaperone.

61 exchange factor (GEF, Mon1-Ccz1), a Rab-GDP dissociation inhibitor (GDI) complex (prenylated Ypt7-GD

62 The Rho-GDP guanine nucleotide dissociation inhibitor (GDI) complexes with the GDP-boun

63 idue conserved domain that acts as a guanine dissociation inhibitor (GDI) for G(i/o)(alpha) subunits.

64 B1 is a calcium-dependent guanine nucleotide dissociation inhibitor (GDI) for Galpha(i1).

65 proteins; it serves as a guanine nucleotide dissociation inhibitor (GDI) for Galphas using the same

66 Gialpha and Goalphaand a guanine nucleotide dissociation inhibitor (GDI) for Gialpha.

67 th GTPase-accelerating protein (GAP) and GDP dissociation inhibitor (GDI) functions, and eIF2B is the

68 TrkBT1 interacted with Rho GDP dissociation inhibitor (GDI) in vivo, but Flag-TrkBT1Del

69 Guanine nucleotide dissociation inhibitor (GDI) is an essential protein req

70 Rab-GDP dissociation inhibitor (GDI) is an important modulator o

71 and GTP hydrolysis on Cdc42Hs by the Rho GDP-dissociation inhibitor (GDI) is extremely sensitive to c

72 on, was perturbed by modest increases in GDP dissociation inhibitor (GDI) levels.

73 hannels are subject to regulation by guanine dissociation inhibitor (GDI) proteins like LGN, a mammal

74 haromyces cerevisiae, the guanine nucleotide dissociation inhibitor (GDI) Rdi1 recycles Cdc42 through

75 Guanine nucleotide dissociation inhibitor (GDI) regulates the recycling of

76 The GDP dissociation inhibitor (GDI) solubilizes prenylated Rab

77 mediated by interaction with the protein GDP dissociation inhibitor (GDI) that binds to prenylated in

78 n signaling 3 (AGS3) is a guanine nucleotide dissociation inhibitor (GDI) that contains four G protei

79 h its RGS domain and as a guanine nucleotide dissociation inhibitor (GDI) through its GoLoco motif.

80 Guanine nucleotide dissociation inhibitor (GDI), a protein that extracts Ra

81 AGS3, a guanine nucleotide dissociation inhibitor (GDI), binds and stabilizes Galph

82 aS binding assays, AGS3 behaves as a guanine dissociation inhibitor (GDI), inhibiting the rate of exc

83 Rdi1, a guanine nucleotide dissociation inhibitor (GDI), mediates a fast recycling

84 itory exchange factor Rho-guanine nucleotide dissociation inhibitor (GDI), or Clostridium botulinum C

85 Membrane-bound GDP-Rabs interact with GDP dissociation inhibitor (GDI), resulting in the dissociat

86 cture of the bovine alpha-isoform of Rab GDP-dissociation inhibitor (GDI), which functions in vesicle

87 reported to function as a guanine nucleotide dissociation inhibitor (GDI), which inhibits Cdc42 activ

88 Rush also directly binds to Rab GDP dissociation inhibitor (Gdi), which is involved in the a

89 for Rab localization and function is Rab GDP dissociation inhibitor (GDI), which is proposed to recyc

90 Guanosine nucleotide dissociation inhibitor (GDI), which regulates the cycle

91 rane localization and the guanine-nucleotide dissociation inhibitor (GDI)-like domain of YopO coopera

92 ence variability in their guanine nucleotide dissociation inhibitor (GDI)-like domains, and demonstra

93 c Cdc42 recycling through Guanine nucleotide Dissociation Inhibitor (GDI)-mediated membrane extractio

94 complexed with its cytosolic chaperone, GDP dissociation inhibitor (GDI).

95 ions bound to a cytosolic protein termed GDP-dissociation inhibitor (GDI).

96 e a bi-functional protein that acts as a GDP dissociation inhibitor (GDI).

97 maintained in the cytosol by binding to GDP-dissociation inhibitor (GDI).

98 Galpha(i1) and acts as a guanine nucleotide dissociation inhibitor (GDI).

99 essed with or without Rho-guanine nucleotide dissociation inhibitor (GDI)alpha.

100 e each flanked by genes encoding Rho guanine-dissociation inhibitors (GDI), known regulators of RhoGT

101 heir function appears to be regulated by GDP-dissociation inhibitors (GDI), three of which have been

102 The GDP-dissociation-inhibitor (GDI) for Rho-like GTP-binding pr

103 requires the REP-related guanine-nucleotide-dissociation-inhibitor (GDI).

104 hat regulate the Rab GTPase cycle-Gdi1p (GDP-dissociation inhibitor [GDI]) or Gyp1p/Gyp7p (GTPase-act

105 Guanosine diphosphate (GDP)-dissociation inhibitors (GDIs) belong to one of three cl

106 Guanine nucleotide dissociation inhibitors (GDIs) bind and sequester GTPase

107 present a novel family of guanine nucleotide dissociation inhibitors (GDIs) for G(alpha) subunits fro

108 SESN proteins function as guanine nucleotide dissociation inhibitors (GDIs) for RAGA/B, and interact

109 GTPases, and function as guanine nucleotide dissociation inhibitors (GDIs) for RagA/B.

110 The Rho GDP-dissociation inhibitors (GDIs) negatively regulate Rho-f

111 domain that mimics host guanidine nucleotide dissociation inhibitors (GDIs) of the Rho GTPases.

112 GDP-dissociation inhibitors (GDIs) play a primary role in mo

113 GDP-dissociation inhibitors (GDIs) play a primary role in mo

114 The GDP dissociation inhibitors (GDIs) represent an important cl

115 gulators of Rho proteins, guanine nucleotide dissociation inhibitors (GDIs), form a complex with the

116 s, Gbetagamma, effectors, guanine nucleotide dissociation inhibitors (GDIs), GTPase-activating protei

117 Guanosine diphosphate (GDP) dissociation inhibitors (GDIs), such as activators of G

118 aled a motif conserved in guanine nucleotide dissociation inhibitors (GDIs), which suggested a novel

119 fails to form detectable complexes with GDP-dissociation inhibitors (GDIs).

120 ity to regulatory proteins including Rab GDP dissociation inhibitors (GDIs).

121 ting proteins (GAPs), and guanine nucleotide dissociation inhibitors (GDIs).

122 rred by binding of Rac to guanine-nucleotide dissociation inhibitors (GDIs).

123 Moreover, a Rab guanine nucleotide dissociation inhibitor has been shown to cause Rab3A to

124 uclein on synaptic vesicles and that the GDP dissociation inhibitor.Hsp90 complex that controls Rab3a

125 o demonstrated modulatory roles for Rac1/GDP dissociation inhibitor in glucose-stimulated insulin sec

126 maleimide and recombinant bovine Rab-guanine dissociation inhibitor inhibited beta-lactamase secretio

127 Purified GDP-dissociation inhibitor inhibited homotypic lysosome fusi

128 hat this occurs through enhanced Rho guanine-dissociation inhibitor interaction rather than direct pe

129 Like Rab guanine nucleotide dissociation inhibitor, it forms a 1:1 complex with Rab3

130 otein binding region of Cavce possesses "GDP dissociation inhibitor-like activity" with the same pote

131 ere, we report that FeoB harbors a novel GDP dissociation inhibitor-like domain that specifically sta

132 CARD9 associated with the GDP-dissociation inhibitor LyGDI in phagosomes after bacteri

133 complex I, or of gdi-1, a guanine nucleotide dissociation inhibitor, may act in combination with defe

134 the capacity of Rab9 for guanine nucleotide dissociation inhibitor-mediated extraction from Niemann-

135 from the PM, in a process reminiscent of GDP dissociation inhibitor-mediated membrane recycling of Ra

136 hat does not depend on GTP hydrolysis or GDP dissociation inhibitor-mediated recycling.

137 ent Rab3a mutant, by a dominant-negative GDP dissociation inhibitor mutant unable to recycle Rab3a of

138 rmally analogous to the action of nucleotide dissociation inhibitors (NDI or GDI) for regulatory GTPa

139 differs from that of Rab guanine nucleotide dissociation inhibitor not only in being Ca2+-dependent

140 c42-guanosine diphosphate (GDP) from Rho GDP dissociation inhibitor or for the membrane recruitment o

141 ed by deletion of Rdi1, a guanine nucleotide dissociation inhibitor, or Bnr1, a formin, but was compl

142 asma membrane and were suppressed by guanine dissociation inhibitor overexpression, which removed ect

143 us Cdc42 from Golgi membranes by the Rho-GDP dissociation inhibitor protein fails to solubilize IQGAP

144 Ran also interacts with a guanine nucleotide dissociation inhibitor, RanBP1.

145 rphogenesis, we overexpressed bovine Rho GDP dissociation inhibitor (Rho GDI alpha), which serves as

146 nd identified RDI1, a Rho guanine nucleotide dissociation inhibitor (Rho GDI), as a positive regulato

147 ase 5 and consequent dissociation of Rho GDP dissociation inhibitor (Rho-GDI) from an ezrin/Rho-GDI c

148 Pases activity, by overexpression of Rho GDP dissociation inhibitor (Rho-GDI), inhibited the strain-i

149 Rho-GDP dissociation inhibitors (Rho-GDI) are repressors of Rho-

150 The guanine nucleotide dissociation inhibitor RhoGDI co-precipitates with RhoA,

151 The guanine dissociation inhibitor RhoGDI consists of a folded C-ter

152 ily in the cytoplasm, bound to the guanosine dissociation inhibitor RhoGDI.

153 The guanine dissociation inhibitors RhoGDI and D4GDI inhibit guanosi

154 Rac1 and two known binding partners, Rho GDP dissociation inhibitor (RhoGDI) and p21-activated kinase

155 we found that Rac1 dissociates from Rho GDP dissociation inhibitor (RhoGDI) and translocates to the

156 f both RhoA and Rac1; an increase in Rho GDP-dissociation inhibitor (RhoGDI) binding in the absence o

157 The Rho GDP dissociation inhibitor (RhoGDI) can bind to small GTPase

158 We have investigated the effects of Rho GDP dissociation inhibitor (RhoGDI) on exocytosis induced by

159 The Rho guanine nucleotide dissociation inhibitor (RhoGDI) plays a key regulatory r

160 Rho GDP dissociation inhibitor (RhoGDI) plays an essential role

161 SCN1 and showed that SCN1 is a RhoGTPase GDP dissociation inhibitor (RhoGDI) that spatially restricts

162 anisms underlying the ability of the Rho-GDP dissociation inhibitor (RhoGDI) to elicit the release of

163 depends on its interaction with the Rho GDP dissociation inhibitor (RhoGDI) via the XIAP RING domain

164 Using this screen, Rho guanine dissociation inhibitor (RhoGDI) was identified as a pote

165 egative regulator the Rho guanine nucleotide dissociation inhibitor (RhoGDI), an interaction that is

166 ng of the Rho GTPases is mediated by Rho GDP dissociation inhibitor (RhoGDI), which forms a stable co

167 e a common inhibitor, Rho guanine nucleotide dissociation inhibitor (RhoGDI), which regulates their e

168 in the interaction of Cdc42 with the Rho-GDP dissociation inhibitor (RhoGDI).

169 1 with its inhibitor, Rho guanine nucleotide dissociation inhibitor (RhoGDI).

170 tly shown that reduced expression of the GDP dissociation inhibitor, RhoGDI2, is associated with decr

171 the transgenic overexpression of the Rho GDP dissociation inhibitor RhoGDIalpha.

172 tile anesthetic, halothane, with the Rho GDP dissociation inhibitor (RhoGDIalpha), which binds the ge

173 into the cells was shown to bind to rab GDP dissociation inhibitor, suggesting that this pool of VP2

174 Thus, eRF1 acts as a GTP dissociation inhibitor (TDI) for eRF3, promoting efficie

175 f Ca2+/calmodulin and Rab guanine nucleotide dissociation inhibitor that are available for binding to

176 D4-GDI is a Rho GDP dissociation inhibitor that is widely expressed in hemat

177 Rho-GDIs are a family of Rho GDP-dissociation inhibitors that are critical in modulating

178 complex of Rab5 and GDI (guanine-nucleotide dissociation inhibitor), that was previously demonstrate

179 Fs), GTPase activating proteins, and guanine dissociation inhibitors to achieve the coordinated activ

180 Pases (by preincubation of vesicles with GDP dissociation inhibitor), together with cytosol immunodep

181 We then used immunodepleted cytosol and GDP dissociation inhibitor-treated vesicles to determine whe

182 extraction of rab4 (but not rab11) with GDP dissociation inhibitor was severely attenuated in NPF en

183 the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in their in

184 a), a Rho-family-specific guanine nucleotide dissociation inhibitor, which is involved in important c

185 n Rab5a and phosphorylated EEA-1 and Rab GDP dissociation inhibitor, with the latter causing Rab5a ac