ライフサイエンスコーパス: distamycin A

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します

1 the minor groove DNA-binding natural product distamycin A.

2 ubsequent incorporation into conjugates with distamycin A (1) are described.

3 cognate DNA than either the parent analogue, distamycin A (10-fold), or the structural isomer, f-PyIm

4 ST-NP6 protein competes for DNA binding with distamycin A, an antibiotic that chelates DNA within the

5 rmed that f-ImPyIm is a stronger binder than distamycin A and f-PyImIm and that f-ImPyIm preferential

6 Both distamycin A and Hoechst 33258 can inhibit, to a similar

7 fferently by two minor groove-binding drugs, distamycin A and Hoechst 33258.

8 nor groove-binding drugs such as netropesin, distamycin A and Hoechst33258 and may be a reflection of

9 ove-binders, chromomycin A(3) (GC-specific), distamycin A and netropsin (both AT-specific), have been

10 he structurally related minor groove binders distamycin A and netropsin (K(i) </=1 microM).

11 stoichiometry, and mode of binding of Tel01, distamycin A, and diethylthiocarbocyanine iodide (DTC) t

12 Tel01, distamycin A, and DTC all form complexes with quadruplex

13 T(pS)TT GCG) (A3T2) upon binding of the drug distamycin A at different stoichiometries.

14 Minor groove binding compounds related to distamycin A bind DNA with high sequence selectivity, re

15 y, it is shifted by 1 bp with respect to the distamycin A binding site on this DNA sequence.

16 groove-binding drug chromomycin A3, but not distamycin A, disrupted Tax-enhanced CREB binding to the

17 An AT minor groove-binding drug, distamycin A, disrupted the TBP.TFIIA.DNA complex and re

18 Distamycin A (Dist A) belongs to a class of drugs termed

19 This binding mode is similar to that of distamycin A, even though the dye lacks the hydrogen-bon

20 we found that the GST-Cdc6 can compete with distamycin A for binding to the DNA molecule.

21 Distamycin A has been described as an inhibitor of the c

22 has a 10-fold greater affinity for CGCG than distamycin A has for its cognate, AATT.

23 quence appears to be weaker than that of the distamycin A homodimer to A/T sequences, most likely due

24 ith guanine tetrads of quadruplex DNA, while distamycin A interacts by binding to quadruplex grooves.

25 As distamycin A is a specific reagent that binds noncovalen

26 Distamycin A is a well known polyamide antibiotic that c

27 AT-binding Distamycin A largely blocks nuclear pore assembly, where

28 Distamycin, a minor groove binding drug, is very effecti

29 ing selectivity for several agents including distamycin A, netropsin, DAPI, Hoechst 33258, and bereni

30 erminations of the binding mode of Tel01 and distamycin A to quadruplex oligonucleotides indicate tha

31 aled that binding of f-ImPyIm, f-PyImIm, and distamycin A to their respective hairpin cognate sequenc

32 ies of these agents were compared to that of distamycin A, using a fluorescence intercalator displace

WebLSDに未収録の専門用語（用法）は "新規対訳" から投稿できます。