ライフサイエンスコーパス: distensibility

1 lated endothelial dysfunction and diminished distensibility.

2 ng human myocardium because of reduced titin distensibility.

3 assessed for diastolic and systolic area and distensibility.

4 wed strong graded inverse relationships with distensibility.

5 ents present, which had a graded relation to distensibility.

6 n adiposity; homocysteine had no relation to distensibility.

7 tly regulates the development of ventricular distensibility.

8 eutrophic inward remodeling and an increased distensibility.

9 basal NO production influences large-artery distensibility.

10 , consistent with increased left ventricular distensibility.

11 levels showed no consistent association with distensibility.

12 d to their pulse pressure to assess arterial distensibility.

13 us, and 0.90 (95% CI: 0.74, 1.10) for aortic distensibility.

14 V) was measured to determine arterial volume distensibility.

15 had more prominent effect on arterial volume distensibility.

16 ring pulse wave velocity, aortic strain, and distensibility.

17 ng of PAs, but not relaxin-induced increased distensibility.

18 tex, which may interact with PAs to increase distensibility.

19 myocytes were stretched to investigate titin distensibility.

20 rity, which is explained by resistive vessel distensibility.

21 ) on the whole arm to obtain arterial volume distensibility.

22 were concomitantly reduced, enhancing vessel distensibility.

23 aortic strain (23% versus 29%; P<0.0001) and distensibility (0.47 versus 0.64%/mm Hg; P=0.02).

24 .1% vs. -1.4 +/- 5.9%, p < 0.05), and aortic distensibility (0.69 +/- 0.86 x 10(-3) mm Hg vs. 0.04 +/

25 a decreased stress-induced measure of aortic distensibility (0.8 mm Hg(-3) [range 0.3 to 1.3 mm Hg(-3

26 or C2, 0.98 (95% CI: 0.86, 1.11) for carotid distensibility, 0.99 (95% CI: 0.90, 1.09) for Young's mo

27 FDRs and BAVs had significantly lower aortic distensibility (1.7 +/- 1.4 x 10(-3) mm Hg and 1.4 +/- 2

28 ers, intima-media thickness, compliance, and distensibility; 2) aortic pulse wave velocity; 3) corona

29 sociated metabolic disturbances, to arterial distensibility (a marker of early arterial disease) in 1

30 We related arterial distensibility, a marker of vascular function known to b

31 The predictive value of ascending aortic distensibility (AAD) for mortality and hard cardiovascul

32 ependent changes in thoracic aortic area and distensibility (above that which occurs with aging) coul

33 obesity, FFA levels are elevated and aortic distensibility (AD) reduced in a pattern that predominan

34 s, ejection fraction, LV mass/EDV, or aortic distensibility (AD).

35 PV distensibility also predicted cardiovascular mortality i

36 d large (LAE) arterial elasticity and aortic distensibility among 6,282 participants in the Multiethn

37 ntrations are associated with lower arterial distensibility, an index of circulatory function relevan

38 rvature), aortic arch function (local aortic distensibility and arch pulse wave velocity [PWV]), and

39 stemic vascular resistance, increased aortic distensibility and arterial compliance, and, notably, si

40 Worse distensibility and beta were significantly associated wi

41 with the lowest sex-specific tertiles of the distensibility and compliance coefficients (reversed) an

42 degrees of DA constriction decreased tissue distensibility and contractile capacity.

43 also show that VEGF increases microvascular distensibility and diameter.

44 ng the non-linearity between arterial volume distensibility and external pressure.

45 defines the unfamiliar terms of compliance, distensibility and modulus and indicates how they are me

46 tively with aortic root and ascending aortic distensibility and positively with pulse wave velocity (

47 IMT was measured, and distensibility and stiffness parameter (beta) were calcu

48 tima-media thickness (cIMT) was measured and distensibility and stiffness were calculated to assess c

49 ffect of initial and additional treatment on distensibility and symptoms was evaluated in 7 and 5 pat

50 to be responsible for the compromised aortic distensibility and systemic compliance.

51 m obtained by tonometry (n = 6,336); carotid distensibility and Young's elastic modulus at the caroti

52 onstrated hypertrophy, a further increase in distensibility, and a highly significant loss of myogeni

53 to derive aortic stiffness measures (strain, distensibility, and beta-stiffness index) at the aortic

54 rrent study reveals changes in artery sizes, distensibility, and blood flow pattern in young adult IU

55 ent is associated with decreased ventricular distensibility, and it may provide a causal mechanism li

56 arotid intima-media thickness (CIMT), aortic distensibility, and large and small arterial elasticity

57 ures of pulse wave velocity (PWV) and aortic distensibility (AoD) in the thoracic aorta at baseline,

58 Aortic function measures (distensibility, aortic strain, and pulse wave velocity)

59 changes in proximal thoracic aortic area and distensibility are associated with exercise intolerance

60 FMD and arterial distensibility are critical components of the exercise r

61 cle (eg, aortic arch pulse wave velocity and distensibility) as well as the various early and late ma

62 thelin-1, acting locally, regulates arterial distensibility, assessed by measuring pulse-wave velocit

63 tolic dysfunction, and an increase in aortic distensibility at all levels of the aorta, most pronounc

64 ess (pulse pressure/LVSV(index)), and aortic distensibility at rest and during intravenous dobutamine

65 etecting significant differences in coronary distensibility between patients with DM and healthy agin

66 of external cuff pressure on arterial volume distensibility between peripheral arteries with differen

67 changes in proximal thoracic aortic area and distensibility (beyond that which occurs with normal agi

68 eveal a novel mechanism whereby loss of wall distensibility blunts endothelial cell protection to oxi

69 ccurred after T3-SCI with a 40% reduction in distensibility (both P < 0.05), and a 33% reduction in v

70 sterol levels were also inversely related to distensibility, but less strongly than adiposity; homocy

71 , all antihypertensive agents improve aortic distensibility, but no agents do so directly; the nitrat

72 Assessment of EGJ distensibility by EndoFLIP is a better parameter than LE

73 in response to cuff ischemia, carotid artery distensibility by high-resolution ultrasound, left ventr

74 NP would increase left ventricular diastolic distensibility by phosphorylating titin.

75 e significant differences in arterial volume distensibility changes were observed between the two arm

76 t demonstrated a modest increase in arterial distensibility compared with those fed the depleted diet

77 Aortic distensibility correlated negatively with the aortic are

78 contrast to controls pulse wave velocity and distensibility correlated with age in patients (P=0.04 t

79 In patients with achalasia, EGJ distensibility correlated with esophageal emptying (r =

80 Even when LES pressure was low, EGJ distensibility could be reduced, which was associated wi

81 The esophageal distensibility (CSA vs pressure) was reduced in EoE pati

82 s in late-stage cardiomyopathy, when chamber distensibility declines.

83 dal alveolar pressure/area curve (reflecting distensibility) decreased with increasing positive end-e

84 Pulmonary vascular (PV) distensibility, defined as the percent increase in pulmo

85 Esophageal distensibility, defined by the change in the narrowest m

86 These data suggest that decreased carotid distensibility does reduce baroreflex function with age,

87 t HA is not essential for increased cervical distensibility during late pregnancy.

88 .3 +/- 3.5%, p = 0.88), and carotid arterial distensibility (ET: 0.97 +/- 0.56 vs. CT: 1.07 +/- 0.34

89 onstrictor responses were lower and vascular distensibility greater in arteries from spaceflight grou

90 he lowest, compared with the highest, aortic distensibility had an increased risk of hypertension (IR

91 nd LDL cholesterol and diastolic pressure to distensibility had been present at 9 to 11 years of age,

92 Peripheral arterial distensibility has been shown to be significantly lower

93 udies of one of these determinants, arterial distensibility, have led to results that now have clinic

94 .51 (95% CI: 1.11 to 2.06) for lower carotid distensibility; HR: 1.19 (95% CI: 1.00 to 1.41) and 1.28

95 .27 (95% CI: 0.90 to 1.79) for lower femoral distensibility; HR: 1.25 (95% CI: 0.96 to 1.63) and 1.47

96 her ex vivo tests including decreased tissue distensibility, hydration, and elevated progesterone lev

97 sed CV risk is associated with lower carotid distensibility, impaired baroreflex function and reduced

98 sal of both diastolic dysfunction and aortic distensibility impairment.

99 trasound was used to measure brachial artery distensibility in 294 healthy adolescents (aged 13 to 16

100 c phases permit measurements of large-vessel distensibility in a phantom model and that vessel disten

101 wider understanding of the role of arterial distensibility in hypertension.

102 regional blood flow, blood vessel sizes, and distensibility in IUGR baboons (8 males, 8 females, 8.8

103 This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occl

104 contractility and enhances left ventricular distensibility in patients with DCM, but not in subjects

105 Relaxin also increased PA distensibility in SHRs (34+/-2 vs. 10+/-2% in SHRs, P<0.

106 in all regions of the ECs and an increase in distensibility in the central regions when measured usin

107 cholesterol levels had an impact on arterial distensibility in the first decade of life.

108 Mild decrease in distensibility in the IUGR group was seen in the iliac b

109 and BNP improves left ventricular diastolic distensibility in vivo, in part by phosphorylating titin

110 cantly related to decreased ascending aortic distensibility, increased aortic arch PWV (p < 0.001), a

111 To assess diastolic distensibility independently of load/extrinsic forces, t

112 n vena cava diameter measured by ultrasound (distensibility index >15%) predicted fluid responsivenes

113 essure (ePAD) of 16+/-9 mm Hg, and diastolic distensibility index (ratio of ePAD to end-diastolic vol

114 /-11 mm, ePAD of 18+/-7 mm Hg, and diastolic distensibility index of 0.06+/-0.04 mm Hg/mL (P<0.05 ver

115 nt effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechan

116 We hypothesized that PV distensibility is abnormally low in patients with heart

117 EGJ distensibility is impaired in patients with achalasia an

118 Furthermore, PV distensibility is modifiable with selective pulmonary va

119 PV distensibility is reduced in patients with HF and pulmon

120 subject in the normal group had an arterial distensibility lower than 0.04% per mmHg, in comparison

121 ng decreased left ventricular compliance and distensibility (LVCD).

122 Measuring esophageal distensibility may be an important adjunct to the manage

123 an carotid wall area and no effect on aortic distensibility, measured at 3 separate anatomic sites.

124 sonography (n = 6,531 and 6,528); and aortic distensibility, measured using cardiac magnetic resonanc

125 nsibility in a phantom model and that vessel distensibility measurement in humans may be possible.

126 is study was to prospectively examine vessel distensibility measurements by using electrocardiographi

127 Arterial distensibility measures, generally from pulse-wave veloc

128 Vessel distensibilities (mm Hg(-1)) were similar for elite rowe

129 do not prevent the decreased compliance and distensibility observed with healthy, sedentary aging.

130 /+) mice on control diet, an indication that distensibility of cerebral arterioles was increased in m

131 sociated with hypertrophy and an increase in distensibility of cerebral arterioles.

132 The shear moduli and distensibility of ECs were greater when using small inde

133 es in the compliance of the vessel wall, the distensibility of microvessels was measured before and 2

134 r findings demonstrated that arterial volume distensibility of peripheral arm arteries increased with

135 , carotid intimal-medial wall thickness, and distensibility of the carotid arteries using ultrasonogr

136 of the breast duct orifices, determining the distensibility of the duct, and developing a reliable te

137 We investigated whether assessment of the distensibility of the EGJ is a better and more integrate

138 Fundoplication restores distensibility of the EGJ to a level similar to normal s

139 We measured distensibility of the EGJ using an endoscopic functional

140 Distensibility of the esophagogastric junction (EGJ) lar

141 o have a significant role in the support and distensibility of the juxtacanalicular region under coll

142 s 356.8+/-113.4 mm(2)/m; P<0.01) and reduced distensibility of the thoracic aorta most pronounced at

143 FG do not exhibit abnormal proximal thoracic distensibility or LV hypertrophy relative to individuals

144 was associated with decreased carotid artery distensibility (P < .01) and increased Young's modulus (

145 ac cycle-dependent change in aortic area and distensibility (p < 0.0001) that correlated with diminis

146 albuminuria were not associated with aortic distensibility (P = 0.26, 0.48, 0.45).

147 r IMT (P=0.03) and beta (P<0.0001) and lower distensibility (P<0.001).

148 6.0; P<0.01) and correlated with aortic root distensibility (P=0.004).

149 fil or placebo led to a 24.6% increase in PV distensibility (P=0.015) in the sildenafil group only.

150 velocity (P=0.0098), strain (P=0.0099), and distensibility (P=0.015).

151 The carotid distensibility/pressure and elastic modulus/wall stress

152 Aortic dimensions, distensibility, pulse wave velocity, aortic arch angle,

153 medications independently predicted abnormal distensibility (R2=0.38, P=0.002) and beta (R2=0.25, P=0

154 ular diastolic function impaired, and aortic distensibility reduced in the obese.

155 mmHg, the overall changes in arterial volume distensibility referred to those without external pressu

156 tions were associated with impaired arterial distensibility (regression coefficient, -1.3% change in

157 icular relaxation and can impair ventricular distensibility resulting in diastolic dysfunction appare

158 Decreased proximal aorta distensibility significantly predicted all-cause mortali

159 alculated values included CCA compliance and distensibility, systemic compliance, stroke volume and p

160 d glyceryl trinitrate both increase arterial distensibility, the former mainly through NO production.

161 in a multivariate analysis, thoracic aortic distensibility was a significant predictor of peak exerc

162 PV distensibility was associated with change in right ventr

163 PV distensibility was derived from 1257 matched measurement

164 At baseline, LV distensibility was greater in committed (21%) and compet

165 The distensibility was increased 45 +/- 15% by VEGF but this

166 PV distensibility was lowest in the pulmonary arterial hype

167 Brachial artery distensibility was measured by a noninvasive ultrasound

168 alloproteinase 9 (MMP-9) activity and tissue distensibility was observed in the cervix in both models

169 <18 years of age; 60% male), ascending aorta distensibility was reduced in comparison with published

170 EGJ distensibility was significantly higher in patients succ

171 ly higher by 2.3 m/s (P < 0.01) and arterial distensibility was significantly lower by 0.015% per mmH

172 EGJ distensibility was significantly reduced in untreated pa

173 Arterial distensibility was significantly related to systolic and

174 Inverse associations with distensibility were also observed for insulin resistance

175 ions and mechanisms underlying loss of titin distensibility were assessed in failing human hearts.

176 Patients with less vena cava distensibility were not as likely to be fluid responsive

177 ffness (pulse wave velocity/analysis, aortic distensibility) were measured before run in and after 40

178 rial wall properties, such as CCA and aortic distensibility, were the same.

179 Specifically, decreased carotid distensibility with age may blunt the arterial barorefle

180 4 mg/kg/d, 14 d) had no effect on increased distensibility with relaxin, but caused outward hypertro

181 es were shifted leftward, toward a decreased distensibility, with increasing age.

182 l because any therapeutic increase in aortic distensibility would decrease systolic pressure without

183 rtery intima-media thickness, carotid artery distensibility, Young's elastic modulus, and blood press