ライフサイエンスコーパス: distinct

1 c systems were both spatially and temporally distinct.

2 mulations confirm that such bands arise from distinct acoustic phonons, connecting different valley s

3 Visual rating scales can be used to identify distinct AD subtypes.

4 this virus, an effective vaccine would have distinct advantages over current therapeutic options, ye

5 racts from behaviorally tested mice revealed distinct age-dependent patterns of accumulation in multi

6 tigen drives differentiation of cells with a distinct agonist-selected phenotype.

7 h also allowed us to study the properties of distinct AML subclones, including differential drug susc

8 The amino-terminal domain with a fold distinct among known TRP structures, together with the c

9 e bacterial communities are similar, but are distinct among lineages, which is consistent with our re

10 microtubules and intermediate filaments have distinct and complementary roles in integrating the nucl

11 esults of this study suggest mechanistically distinct and potentially nonredundant roles for high- an

12 gnatures of S1 and S2 proximal tubules to be distinct and resolvable at the subcellular level.

13 OTCH pathway activation were also clinically distinct and were associated with better overall surviva

14 that transmitted viruses are phenotypically distinct, and that increased IFN resistance represents t

15 We demonstrated marked though distinct anti-silencing activity in the pluripotent stat

16 the somatic diversification of structurally distinct antigen receptor genes evolved independently in

17 ure of macrophages, phagocytosis imprinted a distinct antiinflammatory profile.

18 come-specific conditioned inhibitors for two distinct appetitive outcomes.

19 We hypothesized that TOGs have distinct architectures and tubulin-binding properties th

20 On ICGA, quiescent CNV appeared as a distinct area of hyperfluorescence (vascular network) in

21 ing in wound healing and regeneration as two distinct aspects of cellular self-repair by examining a

22 Storms from different dust origins exhibited distinct bacterial communities, with signature bacterial

23 osition of the microbiota, the presence of 3 distinct bacterial taxa was correlated with protection a

24 s delineate a neural network that integrates distinct behavioral modules and suggest that central amy

25 mics of the extracellular loops of OprH show distinct behaviors in different LPS environments.

26 imulations revealed that these ligands adopt distinct binding poses and engage different subsets of r

27 f 2 isoforms, ERalpha and ERbeta, which have distinct biologic functions.

28 in-dependent cytosolic metabolic roles and a distinct biotin-independent nuclear coregulatory functio

29 evolution on land and different groups have distinct body shapes.

30 exual men, and provides initial evidence for distinct brain activity patterns in bisexual men.

31 We further find that effects of Tel1 are distinct but partially overlapping with previously descr

32 numerated the costs associated with two very distinct but representative DNA and RNA viruses, namely,

33 We tested the hypothesis that distinct Ca(2+) domains are maintained by Ca(2+) uptake

34 ises the ability of mitochondria to maintain distinct Ca(2+) domains.

35 ggested that different frequency bands index distinct canonical computations.

36 ant influence of mixing between isotopically distinct Cd end-members was confirmed by a Bayesian mode

37 networks, we observed and characterized two distinct Cdc8 cables loading and spreading cooperatively

38 Understanding the implications of distinct cell death pathways will help in the developmen

39 revealed primary and metastatic cells as two distinct cell populations defined by differential expres

40 VMP and adjacent mesenchyme were composed of distinct cell types and that each tissue contained two s

41 The resulting explosion in the number of distinct cell types being identified is challenging the

42 istent itch and inflammation are mediated by distinct cellular and molecular mechanisms in a mouse mo

43 Distinct cellular barriers that protect primary human bl

44 We demonstrate that two distinct chemical entities contribute to the temporal ev

45 used on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties.

46 This study reveals distinct cingulo-insular alterations for FND and PTSD sy

47 hic distributions of multiple, antigenically distinct clades of HPAI A(H5) viruses in Vietnam, the va

48 FRAL), a distant relative of receptors for a distinct class of the TGF-beta superfamily ligands.

49 n as the key computational signatures of two distinct classes of RL models-namely, "actor/critic" mod

50 and distribution of five beta2 agonists with distinct clinical durations and onsets of action (indaca

51 Principal components analysis revealed distinct clustering of cell types across samples, while

52 The presence of Halomonas spp. in three distinct co-occurrence networks of bacterial interaction

53 We observed intense fluorescence in distinct compartments of the protozoa, but not in the ba

54 ntion, reducing CH4 emissions is an entirely distinct concept from biological C sequestration project

55 ligand and an amino ligand to zinc occurs in distinct confined environments, reminiscent of substrate

56 The Axl crystal structure revealed two distinct conformational states of the enzyme, providing

57 the on-pathway, suggesting the generation of distinct conformeric strains of Abeta, which may have pr

58 ion differed between AtPMEI4 and AtPMEI9 had distinct consequences on pollen tube elongation.

59 cating that the HTLV-1 CA subdomains provide distinct contributions to Gag-Gag oligomerization, parti

60 Canonical IN types conserved across distinct cortical regions have been defined by their mor

61 As an example, three distinct D-versus-sigma "signatures" are calculated, cor

62 Price increases for SSBs in two distinct data sources, their timing, and the patterns of

63 We validate DAMACY by using three distinct datasets: in vivo response of neutrophils evoke

64 Distinct daughter identities can result from the physica

65 sits bury relic intertidal deposits at three distinct depths.

66 ironment with extreme climate conditions and distinct dietary resources.

67 pins, Stella, Sweetheart and Staccato), with distinct differences in anthocyanins and vitamin C conte

68 n of differentially expressed genes revealed distinct differences in biological functions and pathway

69 -39), revealing both similarities as well as distinct differences in the mode of interaction.

70 genetically cross two lethal parasites with distinct disease phenotypes, and identify 43 genetically

71 nies juvenile psoriatic arthritis might be a distinct disease that is particularly severe when its on

72 In conclusion, there are distinct distribution patterns of circumferential and lo

73 ified five tags that react orthogonally with distinct DNA sequences.

74 to its ability to bind to CdGAP and Rac1 via distinct domains and influence the activation status of

75 only 1 of these patients (0.9%) developed a distinct ductal adenocarcinoma.

76 Phase 2 started with the distinct elongation of a single sarcomere, the so-called

77 this reaction deletion constraint becomes a distinct EM.

78 Exposure to 13 physicochemically distinct ENMs caused a range of mast degranulation respo

79 MAbs 5B4 and 6H4 recognize structurally distinct epitopes present in the vast majority of Bet v

80 in functional studies, for the modulation of distinct facets of homeostasis.

81 elf, as well as the subsequent activation of distinct fate programmes in each daughter.

82 cificity of the H15 hemagglutinin, revealing distinct features and specificities that can aid in glob

83 of steroid hormone signaling in the brain on distinct features of birdsong using adult male canaries

84 ause of the nature of the ARG, there are two distinct features related to the waveguide: i) It is not

85 roperties of KaiB, a protein that adopts two distinct folds, and the post-adenosine triphosphate hydr

86 lso predict the adhesion force profile to be distinct for CaCl2 compared with the other electrolytes.

87 and assess the techniques used to determine distinct forms of spider silk chemical and physical prop

88 Using 3'RACE, we confirmed expression of two distinct forms of the HLA-A 3'UTR based on use of either

89 MMP9 highly efficiently cleaved DSP into distinct fragments in vitro, and the deletion of Mmp9 ca

90 hologic and calcification patterns that were distinct from archetypical physeal endochondral ossifica

91 er, we demonstrate that contact frequency is distinct from average spatial distance, both in polymer

92 onal profiles of individual cell populations distinct from bulk skin, most strikingly in the least ab

93 have been identified in the thymus that are distinct from conventional Th17 and Th1 cells.

94 sport defects observed in actr10 mutants are distinct from dynein and dynactin mutant axonal phenotyp

95 lapsed conformations via a mechanism that is distinct from glycine and betaine.

96 an adhesion macromolecule expression pattern distinct from Hodgkin and Reed-Sternberg cells of classi

97 and the antigen-presenting molecule CD1d is distinct from interactions between the TCR and major his

98 Metabolite patterns were distinct from nitrogen starvation and other abiotic stre

99 h a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus,

100 the initiation mechanism in mitochondria is distinct from that in the well-studied nuclear, bacteria

101 tching characteristics are observed that are distinct from that in thicker medium due to the profound

102 raphic symmetry axis, a conformation clearly distinct from that of actin subunits in the helical fila

103 olecular pattern of children with EoE is (i) distinct from that of healthy children; and (ii) differe

104 This mechanism is distinct from the BRCA2-dependent fork protection pathwa

105 malian RNAs can harbor a 5' end modification distinct from the classical m(7)G cap that promotes rath

106 stromal extracellular matrix (ECM), which is distinct from the ECM within the normal epithelial micro

107 hages, hepatocytes, and adipocytes, which is distinct from the effect of STING activation by DMXAA on

108 irway SM contraction that is independent and distinct from the function of SM myosin.

109 This phenotype was distinct from the Golgi fragmentation observed in apopto

110 s were isolated from forests, and these were distinct from the ocean sediment isolates.

111 an be ligands of human CYP2C8, making CYP2C8 distinct from the other CYP isoforms.

112 ure of these networks with a unique topology distinct from the parent PPIN.

113 bind sialic acid via a separate binding site distinct from the sialidase active site.

114 we find that the HIV-1 Vif-A3H interface is distinct from the Vif-A3G and Vif-A3F interfaces, with a

115 gap spectrum and density of states, clearly distinct from the widely known, bulk-like sigma- and pi-

116 riggering signaling and functional responses distinct from those activated by the endogenous cytokine

117 ngly, the adaptive changes in RBF206 Vpu are distinct from those found in M-Vpus and mediate efficien

118 t injury responses in this species are quite distinct from those in other mammalian species.

119 synthesize acylsugars that are structurally distinct from those of tomato.

120 und that the inputs that activate sna-DP are distinct from those that activate Distalless, a marker f

121 LHb afferents to the pVTA are distinct from those to the RMTg, given that the RMTg is

122 Multiple memory CD8(+) T-cell subsets with distinct functional and homing characteristics exist, bu

123 sists of many different cell types that have distinct functional roles and are subject to different e

124 groups when functional site features suggest distinct functionally-relevant clusters.

125 linical presentations, indicating shared and distinct functions for each complex member.

126 tory effects could allow PMd and PMv to play distinct functions for the control of hand movements and

127 es share subunits and that RPA subunits have distinct functions in different heterotrimer assemblies.

128 is an important subcortical area involved in distinct functions such as multimodal integration, movem

129 spectively, suggesting that each complex has distinct functions that are perturbed upon BAF47 loss.

130 ssical, intermediate, and nonclassical) with distinct functions, however, the recruitment order of th

131 eep, reveal at least two phylogeographically distinct genepools of fat-tail sheep in Africa that diff

132 ct in glomerular refinement, suggesting that distinct genes or sets of genes underlie visual and olfa

133 ene-centric dependencies across multiple and distinct genomic platforms.

134 ese diseases, it is not fully understood how distinct GJB2 mutations result in hearing loss alone or

135 alacturonan-II, cleaving all but 1 of its 21 distinct glycosidic linkages.

136 with psychogenic memory loss fell into four distinct groups, which we categorized as: (i) fugue stat

137 measures form structurally and functionally distinct groups.

138 snitzii) were associated with geographically distinct human populations, whereas few strains occurred

139 dataset comprising measurements of up to 168 distinct hydrocarbon analytes in 2,980 sediment samples

140 nded clones from two T1D subjects recognized distinct IGRP peptides, implicating this molecule as a t

141 Trial designs should consider the distinct immunological features of each transplanted org

142 CD26 identifies three T helper subsets with distinct immunological properties in both healthy indivi

143 ributions of P. simiae genes to growth in 90 distinct in vitro conditions by RB-TnSeq, highlighting s

144 controlled by a glutamate-binding site and a distinct, independently regulated, co-agonist-binding si

145 ral models of the perfluoroarylated product, distinct interactions at 4.7 A between Phe1 side chain a

146 rechallenge with the homologous as well as a distinct isolate with only minute amounts of circulating

147 However, we observe distinct kinetic profiles, even for proximal sites, and

148 ncements are likely required for visualizing distinct kinetic steps of transcription on a single-copy

149 hereas p-ERK associates predominantly with a distinct KSR1-positive endosomal population.

150 ions, suggesting that the two peptides adopt distinct lateral packing of the diffracting units.

151 density functional theory calculations, show distinct layer-dependent semiconductor-to-semimetal evol

152 ensity gradients results in the formation of distinct layered patterns, such as those observed in the

153 rior colliculus similarly consisted of seven distinct layers.

154 and (3) multifocal disease with genetically distinct lesions.

155 ted the effects of agents designed to target distinct levels of the IL23 and Th17 cell pathways, and

156 coexisting across continental Europe, while distinct lineages exist in isolation throughout the UK.

157 mantle lithosphere leads to the formation of distinct margin domains.

158 vealed the co-occurrence of approximately 50 distinct mass spectrometry (MS) signals.

159 termine whether synchronous spikes possess a distinct meaning for the encoding of time-dependent sign

160 impact on microtubule dynamics suggesting a distinct mechanism of action.

161 xpressing HPV E6 and E7 hinders HR through a distinct mechanism.

162 lase, lipase, and sulfatase), relying on two distinct mechanisms for coupling droplet morphology to e

163 ociated T cells might promote malignancy via distinct mechanisms used by T cells in nonlymphoid organ

164 Treg cell metabolism and IL-4 production via distinct mechanisms, as IL-4 deficiency does not prevent

165 gulates HAV IRES-mediated translation by two distinct mechanisms.

166 ause migraine-like photophobia by apparently distinct mechanisms.

167 ce between excitation and inhibition through distinct mechanisms.

168 the control structures by which signals from distinct mechano-sensors are integrated to modulate hype

169 differentially dysregulated genes uncovered distinct MEF2A co-regulators for the atrial and ventricu

170 uch needed drugs that selectively target the distinct members of the NOX family and interfere with RO

171 d three sessions occurring during hormonally distinct menstrual cycle phases.

172 t, which invokes homeotic shifts in multiple distinct meristem identities, obscures a recurring theme

173 s) rely on glycolysis for proliferation, the distinct metabolic features of regulatory T cells (Tregs

174 e in vitro enzyme assays indicate that these distinct metabolic phenotypes reflect the divergence of

175 the same cemeteries harbouring taxonomically distinct microbial communities.

176 e a wide range of nucleic acid analytes into distinct microchannel outlets.

177 lar expression profiling tools to define the distinct miRNA expression of MNs, which is likely to enr

178 Moreover, the domains disappear above a distinct miscibility transition temperature (Tmix) and r

179 rst, we find that across three etiologically distinct models-in utero valproic acid (VPA) exposure, C

180 vation of different type I BMP receptors and distinct modulations of the cell cycle.

181 reveals that the protein is a fusion of two distinct modules: an N-terminal sugar phosphate isomeras

182 or posterior fossa) and further divided into distinct molecular subgroups that reflect differences in

183 g regions of the TRs were labeled with three distinct monolayer double-stranded (ds) DNA-gold nanopar

184 LFAO-seeded fibrils possess distinct morphology made of repeating LFAO units that co

185 2) Est1 employs two separate pockets to bind distinct motifs of Cdc13.

186 e demonstrate differential regulation by two distinct mSWI/SNF assemblies, BAF and PBAF complexes, en

187 Two distinct nearly full-length Rhizobiales genomes were ide

188 le immunoglobulin (Ig) domain, instructs the distinct, neuron-type-specific elaboration of ciliated e

189 rve function at the wrist by somatotopically distinct neuroplasticity in the primary somatosensory co

190 that vaccine induction of multiple NAbs with distinct neutralization profiles is likely to enhance th

191 Fungal cells colonize and proliferate in distinct niches, from soil and plants to diverse tissues

192 e properties may contribute to inhibition of distinct NMDAR subpopulations by memantine and ketamine

193 more, we identified splice variants encoding distinct nuclear and cytoplasmic isoforms of fusilli, th

194 Although there are distinct ocular advantages to anti-VEGF pharmacotherapy

195 Distinct oligomeric states of the Marburg and Ebola viru

196 ternal pH is above the threshold, triggering distinct OmpR-related pathways.

197 GMF induced two distinct open conformations of Arp2/3 complex, which cor

198 ow velocity zones validate a compositionally distinct origin for most ultralow velocity zones.Ultralo

199 terial communities in dust storms from three distinct origins (North Africa, Syria and Saudi Arabia)

200 ems, wherein specific input sequences create distinct outputs.

201 eneities as a function of size or chemically distinct particle surfaces can determine the hygroscopic

202 is not through redundancy, but regulation of distinct pathways.

203 First, distinct patterns of activation occur in response to dif

204 ysiological subtypes ('biotypes') defined by distinct patterns of dysfunctional connectivity in limbi

205 d 3'ss usage and exon skipping are marked by distinct patterns of ordered intron removal.

206 We therefore propose that distinct perceptual features of odors are encoded in ind

207 DSM-5 describes "a distinct period of abnormally and persistently elevated,

208 nd beta-cellular clocks are oscillating with distinct phases in vivo and in vitro.

209 tral olfactory stimuli, designed to separate distinct phases of reward processing.

210 loss of S100A4 produces two mechanistically distinct phenotypes with regard to macrophage invasion:

211 light responses in each strain gives rise to distinct photophysiological phenotypes that may affect S

212 cells closer to the surface and can display distinct photophysiological status.

213 ous work suggests that MLCK and ROCK control distinct pools of cellular SFs, it remains unclear how t

214 ivIVA-like protein Cdv3, indicating that two distinct pools of MinC are coordinated in S. elongatus.

215 iterranean fin whales comprise a genetically distinct population, listed as Vulnerable (VU) in the IU

216 sing 2Phatal, we achieve precise ablation of distinct populations of neurons, glia and pericytes in t

217 rst analysis of OCRs and TF-binding sites in distinct populations of postmortem human brain cells and

218 al circuits and synaptic mechanisms by which distinct populations of RVM neurons facilitate or dimini

219 Six distinct postoperative inpatient patient-reported pain t

220 amorphous states are distinguished by their distinct pressure derivatives of the bulk and shear modu

221 Cases 1 and 4 were verified as genetically distinct primary tumors and did not harbor similar copy

222 for membrane perforation represents another distinct process that contributes to the molecular basis

223 r increase or decrease fear response through distinct processes known, respectively, as reconsolidati

224 genization of chemical species, yielding two distinct processes that are seemingly opposed yet synerg

225 lysis of synovial fluid showed significantly distinct profiles between groups with 125 differentially

226 s indicate that metabolic heterogeneity is a distinct property of activated beige/brite adipocytes th

227 the coding sequences lead to mRNAs encoding distinct proteins.

228 Thus two distinct proteotoxic stress responses control phospholip

229 erated in previous studies using various and distinct protocols.

230 between the nervous and immune systems using distinct receptors.

231 ons also showed preferential processing in 2 distinct regimes, with the alpha range again yielding di

232 ustering was then used to select images from distinct regions of this feature space.

233 -electrode array in vivo recordings from two distinct regions: olfactory bulb (OB) and anterior pirif

234 resulting in the formation of a structurally distinct replacement.

235 gulatory mechanisms of seed vigor and reveal distinct requirement for RFOs in modulating seed vigor i

236 aspases, with phosphorylation of at least 11 distinct residues in all three caspase-9 domains by nine

237 ors, supported by the common appearance of a distinct resonance in the spin susceptibility across the

238 However, identifying distinct responses will enable novel routes for PTP-sele

239 omote lumen formation, hence demonstrating a distinct role for the R-Ras-Akt axis.

240 retromer component with CSC and also plays a distinct role in the regulation of endosome dynamics dur

241 nteracting proteins, BB0238 and BB0323, play distinct roles in pathogen biology and infectivity altho

242 This difference defines their distinct roles in the regulation of macrophage migration

243 mutation and overexpression that Doc2B plays distinct roles in two sequential priming steps in mouse

244 modulation and mutual inhibition, which have distinct selectivity (feature vs. eye of origin) and dyn

245 The mechanisms of formation of the distinct sensory organs of the inner ear and the non-sen

246 ferent locations of gene are surrounded with distinct sequences in both species and are often associa

247 -selective ON-OFF RGC types that represent a distinct set of feature detectors in the mouse retina.

248 ltransferase for H3K79, forms complexes with distinct sets of co-factors.

249 ple intricate neural networks assembled from distinct sets of input and output neurons as well as reg

250 Bifunctionality is associated with two distinct sets of loop conformations, each essential for

251 imply that electrically coupled neurons have distinct sets of mechanisms for adjusting coupling accor

252 We generated distinct sets of rules for each age group to capture the

253 not known if they are mediated by shared or distinct signaling pathways.

254 We illustrate how distinct signalling mechanisms direct stress-dependent v

255 At the same time, distinct similarities with chiral supramolecular and bio

256 and Sr isotopic measurements suggest that a distinct source may have been present before 10 ka.

257 investigations and review articles) from 15 distinct specialties each year for your review.

258 nalyzed 95 specimens from 11 morphologically distinct species of benthic ctenophores from the Red Sea

259 Notably, more than 42 280 distinct splicing isoforms were derived from 128 667 int

260 iol (E2beta; 2 ng/L and 50 ng/L) during four distinct stages of development: gonad development, gonad

261 In this distinct state, tantalum flows like a viscous fluid whil

262 umors exhibit merged chromatin profiles from distinct stem cell lineages.

263 om supersaturated aqueous solutions in three distinct steps: spinodal decomposition into solute-rich

264 the spacing effect and led neurons to decode distinct stimulation patterns as massed stimulation.

265 s and voltage-gated conductances can extract distinct stimulus features into parallel channels.

266 These distinct structural changes occurring in both Abeta(1-40

267 ors target the same general region, but in a distinct sub-pocket at the interface between helices V a

268 C compartment in mice and humans consists of distinct subpopulations with differing effector function

269 cells promote cancer by remotely supplying a distinct subset of tumor-infiltrating SiglecF(high) neut

270 These neurons are heterogeneous, and distinct subsets are thought to regulate different behav

271 lling on selectins facilitates adhesion to a distinct substrate-bound protein with different kinetic

272 with metastatic CRC and define a clinically distinct subtype of CRC with an excellent prognosis.

273 Distinct subtypes of inhibitory interneuron are known to

274 These functions are served by distinct subtypes of mesodiencephalic dopamine neurons l

275 e activities of these processes define three distinct subtypes of PDAC, which demonstrate differences

276 ester and alcohol compounds associated with distinct 'sulfur-cabbage', 'fruity', 'rosy', and 'boiled

277 mall subunits, PBP1 and PBP2, associate with distinct surfaces of the larger catalytic subunit and in

278 EVS activation engages several kinetically distinct synaptic processes that profoundly alter the di

279 The metabolic programs of functionally distinct T cell subsets are tailored to their immunologi

280 variety of clinical phenotypes that involve distinct T cell-driven inflammatory processes.

281 addressed here, integrates the activities of distinct T-cell subsets and by definition is dynamic and

282 to migratory species, such as salmon, where distinct temporal changes in growth and physiology durin

283 This 3' UTR heterogeneity directs distinct temporal patterns of translational activation o

284 quently, the two pathways diverge to produce distinct thermodynamically stable species (parallel and

285 responses to gravity and water are driven by distinct tissue-based mechanisms.

286 Thus CAPN14 is a unique protease with distinct tissue-specific expression and function in pati

287 essitating a deeper understanding of how the distinct transcriptional programs controlled by these is

288 The simulations revealed a distinct transition between energetically sustainable an

289 These findings suggest that multiple distinct tumor immune microenvironments co-exist within

290 tic vascular disease is often triggered by a distinct type of atherosclerotic lesion that displays fe

291 atest tractions at the cell periphery, where distinct types of actin-based membrane protrusions forme

292 groups, which are differentially enriched in distinct types of protrusions, and are additionally diff

293 endritic endings of sensory neurons organize distinct types of sensory machinery [1].

294 y using radiolabeled verinurad revealed that distinct URAT1 inhibitors benzbromarone, sulfinpyrazone

295 virulence have associated the expression of distinct variants of the major surface antigen of the bl

296 anti-viral effects of methyl-6-adenosine in distinct viral life cycles, the role of 2' O-methyl modi

297 at endocrine-committed cells are molecularly distinct, whereas multipotent and bipotent progenitors d

298 with skins have been developed for obtaining distinct white wines.

299 Our strategy establishes a distinct yet complementary set of imaging probes for und

300 Ku specifically binds to telomerase RNA in a distinct, yet related, manner to how it binds DNA; and (