ライフサイエンスコーパス: divalent

1 e under-hydroxylation was shown to alter the divalent aldimine cross-link chemistry of mutant skin co

2 nic monovalent cation, ethidium, but not its divalent analog, propidium.

3 and indicated that affinity is increased for divalent analogues.

4 Divalent and tetravalent displays of M2pep ([M2pep]2-Bio

5 Surprisingly, both divalent and tetravalent M2pep, without conjugation of a

6 Through the use of organic branching points, divalent and trivalent DNA linkers were readily incorpor

7 DNA-based catalysts; they typically recruit divalent and trivalent metal ions for catalysis.

8 monovalent, divalent) and pH.

9 ed significant differences among monovalent, divalent, and trivalent cation distributions around DNA.

10 oximately 8 for Cx50), whereas permeation of divalent anion glutathione disulfide (GSSG) was undetect

11 Integral membrane proteins of the divalent anion/Na(+) symporter (DASS) family translocate

12 lar system is described, comprising a simple divalent bis(imidazolyl) molecule that is shown to "walk

13 stem from direct insertion of the carbene's divalent C atom into the alpha-bonds of the carbonyl com

14 Ion-surface interactions between divalent Ca(2+) and Mg(2+) ions and the nanochannel wall

15 ate how the adsorption of in nature abundant divalent Ca(2+) cations to solid-liquid interfaces induc

16 by ionically crosslinking in the presence of divalent Ca(2+) ions.

17 otein association and the bridging effect of divalent Ca(2+) ions.

18 m for hardness removal, that is, exchange of divalent Ca(2+) or Mg(2+) with trivalent Al(3+), is coun

19 isplaying only mild preference against other divalents (Ca(2+) > Mn(2+) > Co(2+) > Mg(2+) > Ni(2)(+))

20 udied under a wide range of mono- (NaCl) and divalent (CaCl2) electrolytes and using time-resolved dy

21 Interestingly, the presence of the divalent calcium cation facilitated multilayered SRHA ad

22 state at physiological temperatures and low divalent calcium ion concentrations.

23 f esterification, HG can form complexes with divalent calcium ions.

24 ng them as solid hydrogel matrices by adding divalent calcium ions.

25 and lysine with and without the addition of divalent calcium.

26 mplexes in which gold is bound to a formally divalent carbon atom, typically formulated as gold carbe

27 critical deposition concentration (CDC) for divalent cation (Ca(2+) and Mg(2+)) were more than 31-fo

28 Both structures reveal that the divalent cation and cholesterol binding sites are connec

29 n betaA domain of the beta-subunit through a divalent cation at the metal ion-dependent adhesion site

30 These results show that targeting a divalent cation binding residue can enable selective inh

31 inding cavity; the other is close to a known divalent cation binding site in other pentameric ligand-

32 roup concentration and resultant reduced NOM-divalent cation bridging.

33 otoxin, as well as Ca(2+) free solutions and divalent cation Cav channel blockers, eliminate the outw

34 riotoxin (10 mum), Ca(2+) free solutions and divalent cation Cav channel blockers.

35 Ligases react with ATP or NAD(+) and a divalent cation cofactor to form a covalent enzyme-(lysi

36 The LPS layer is rigid and stabilized by divalent cation cross-links between phosphate groups on

37 We investigated the role of reverse divalent cation diffusion in forward osmosis (FO) biofou

38 Third, divalent cation effects on the 5'-exonuclease and the en

39 riencing low cytosolic magnesium (Mg(2+)), a divalent cation essential for ribosome stabilization and

40 Magnesium (Mg(2+)), the most common divalent cation in living cells, plays crucial roles in

41 te linkage, monodentate or bidendate, to the divalent cation is a useful parameter for tuning the tra

42 is inhibited for activation by acidic pH and divalent cation limitation.

43 Zinc, a divalent cation packaged in synaptic vesicles along with

44 ulent in mice, indicating that acidic pH and divalent cation sensing by PhoQ are dispensable for viru

45 FrvA functions in vitro as a divalent cation specific ATPase most strongly activated

46 e only after the ES complex captures a third divalent cation that is not coordinated by the enzyme.

47 nexin SNX3, and a recycling signal from the divalent cation transporter DMT1-II.

48 these vesicles are a distributed system for divalent cation uptake and release, but in this case the

49 In contrast, in the presence of a divalent cation, GTPgammaS adopts an extended conformati

50 Upon complexation with a divalent cation, the accessible conformational space shr

51 pproximately 16 muM), using an extracellular divalent cation, zinc (Zn(++)), as a nonspecific positiv

52 eals the molecular details of three distinct divalent cation-binding sites identified through electro

53 us-ms time scale and deactivates both of the divalent cation-binding sites of the cTnC C-domain.

54 ate at position Asp-50 was indispensable for divalent cation-dependent gating of Cx30 hemichannels, s

55 Cell interactions were divalent cation-dependent, indicating integrin dependenc

56 The sensitivity toward divalent cation-mediated gating differed between small a

57 fic properties in mind, we characterized the divalent cation-sensitive permeation pathway in primary

58 ed by the gate electrode are impacted by the divalent cation-surface interactions, limiting modulatio

59 ed in binding of the catalytically essential divalent cation.

60 roup was the microcapsules cross-linked with divalent cationic CaCl2 salt (MCS), and the third group

61 Divalent cations (both ion channel and intracage binding

62 , the NSP4 VPD showed similar conductance of divalent cations (Ca(2+) and Ba(2+)) as monovalent catio

63 cs in the presence of monovalent (Na(+)) and divalent cations (Ca(2+)) show that attachment efficienc

64 In the presence NOM and divalent cations (Ca(2+), Mg(2+)), GO aggregates settle

65 ters can destabilize the nanoparticles, with divalent cations (e.g., Ca(2+), Mg(2+)) being more influ

66 Three divalent cations (M(++)=Zn(++), Co(++), Ni(++)) were eva

67 In this study, we investigate the effects of divalent cations (Mg(2+) and Ca(2+)) on RED and demonstr

68 On an aqueous subphase containing divalent cations (Mg(2+), Ca(2+), Zn(2+), Sr(2+), or Cd(

69 identified the fractional surface density of divalent cations (n(s2))as the parameter which best expl

70 ene family known to import Mn, Zn, and other divalent cations across the plasma membrane.

71 Divalent cations and heavy chain 2 are essential co-fact

72 PhoQ activity is repressed by divalent cations and induced in environments of acidic p

73 steric sites on CHRMs respond differently to divalent cations and the effects of allosteric modulatio

74 Like other 5'-nucleotidases, S5nA requires divalent cations and was active in the presence of Mg(2+

75 The role of different divalent cations are discussed in relation to these two

76 pproximately 1.5 mm Our results suggest that divalent cations are not SLO2 pore blockers, but rather

77 of the ion atmosphere content indicates that divalent cations are preferentially lost over monovalent

78 inate can form gel particles in contact with divalent cations as found in seawater.

79 ange County Groundwater Basin sediments, the divalent cations Ca(2+) and Mg(2+) are critical for limi

80 dipeptides, and their interactions with the divalent cations Ca(2+), Ba(2+), Sr(2+), Cd(2+), Pb(2+),

81 we found that ranolazine and elevated serum divalent cations eliminate myotonia by inhibiting AfD an

82 Divalent cations have long been known to neutralize and

83 the present study, we have investigated how divalent cations in concert with the chondroitin sulfate

84 250) in spacegroup I41 and the other without divalent cations in spacegroup P6122.

85 al of the Mg(2+) found in plasma and because divalent cations influence the conformation and affect f

86 , POPC only interacts weakly with Ca(2+); 5) divalent cations interact with lipids in a lipid- and io

87 To investigate whether inhibition by divalent cations is conserved in an invertebrate SLO2 ch

88 significantly lower binding affinity for the divalent cations magnesium and strontium.

89 en the influent water was at pH 5, contained divalent cations or 50 mM NaNO3, silver concentrations w

90 er able to self-associate in the presence of divalent cations or under heat shock.

91 ulated by the intracellular concentration of divalent cations sensed by a large structure in the BK c

92 spatially distinct site for reabsorption of divalent cations such as Ca(2+) and Mg(2).

93 In immune cells, divalent cations such as calcium, magnesium, and zinc ha

94 Electrochemical storage systems that utilize divalent cations such as Mg2+ can improve the volumetric

95 gh, we found that SLO2.2 is inhibited by all divalent cations that activate SLO1, with Zn(2+)being th

96 of SLO2 channels in mammals andDrosophilaby divalent cations that have second messenger functions ma

97 e for radial shear assays in the presence of divalent cations that increase integrin-ECM affinity.

98 Our results imply that it is the removal of divalent cations that makes reservoir rocks more hydroph

99 can be induced by the addition of mono- and divalent cations to aqueous U60 solutions.

100 ent-selective Neosepta CMS is known to block divalent cations transport and can therefore mitigate re

101 permeation properties to both monovalent and divalent cations under perfused two-electrode voltage cl

102 Manganese (Mn) and zinc (Zn) are essential divalent cations used by cells as protein cofactors; var

103 To enable dynamic sensing of divalent cations via PAI, we have engineered a new rever

104 Upon addition of EDTA and EGTA, the divalent cations were sequestered from the stabilized ap

105 organelles rich in polyphosphate chains and divalent cations whose significance in these parasites r

106 f this state is influenced by interaction of divalent cations with both activating and inhibitory cyt

107 alent-permeable Fuji T1 is able to transport divalent cations without a major increase in resistance.

108 KO mice are more sensitive to inhibition by divalent cations, although they respond normally to cyto

109 nduced in environments of acidic pH, limited divalent cations, and cationic antimicrobial peptides (C

110 t, channel activations by capsaicin, low pH, divalent cations, and even heat are mostly intact in mut

111 Overall, pH, divalent cations, and NOM can play complex roles in the

112 In addition, NMCCs do not permeate divalent cations, are inhibited by calcium ions, and dem

113 ve electrostatic trap, with a preference for divalent cations, at the luminal entrance.

114 els, with few showing the ability to conduct divalent cations, like calcium (Ca(2+)).

115 Aided by divalent cations, P4 is poised to act as a "screw cap" o

116 that surprisingly, MdfA catalyses efflux of divalent cations, provided that they have a unique archi

117 0.03 and -0.52 +/- 0.01 with monovalent and divalent cations, respectively, and these results help c

118 ore sensitive to the inactivating effects of divalent cations, thus, in the presence of Mg(2+) , ATP

119 ced Gla residues allow binding of functional divalent cations, which induces end-to-end alpha-helices

120 owever, SLO1 is activated by Ca(2+)and other divalent cations, while SLO2 (Slack or SLO2.2 from rat)

121 .7 muM), and selective for Fe(2+) over other divalent cations.

122 -347) downstream of S6 reduces inhibition by divalent cations.

123 was also activated by Na(+)and inhibited by divalent cations.

124 ly important for cell adhesion in niche with divalent cations.

125 f this mode of detachment in the presence of divalent cations.

126 s ) with to near-zero contact angles without divalent cations.

127 out the effects of environmentally important divalent cations.

128 when performing RED using streams containing divalent cations.

129 erved CAP tetrad and is incapable of binding divalent cations.

130 lent cations up to 5 times more rapidly than divalent cations.

131 e, neighbor sequence of (Si/Al)N4 around the divalent centers were observed through solid-state nucle

132 demonstrate the advantageous effects of the divalent charge on sensitivity.

133 The system relaxes to the lowest manifold of divalent cobalt ((4) T 1) in 150-200 fs.

134 l reactivity of the nitride 2, the resulting divalent cobalt complex 3 is a rare example of a trigona

135 It is theoretically demonstrated that the divalent cobalt ion reaches 90% of the [Formula: see tex

136 t (Ka) was positive and greater than Keq for divalent complex formation.

137 Divalent copper ions when fully exchanged into high-sili

138 The IR spectrum of NO adsorbed to divalent copper sites are modeled using ab initio molecu

139 essence of this strategy involves the use of divalent counterions to temporarily perturb the packing

140 volved in ethylene polymerization are mainly divalent Cr ions in a 6-fold coordination, in interactio

141 cross-linked species involving alpha1/2-87, divalent cross-links were glycosylated with both mono- a

142 y, and low cost due to the ability to employ divalent, dendrite-free, and earth-abundant magnesium me

143 idate competitive sorption processes between divalent Fe and Zn at the clay mineral-water interface.

144 CP coordinates a variety of divalent first-row transition metal ions, which is impli

145 ching from a Ca(2+)-containing solution to a divalent-free Na(+) one, and fast Ca(2+)-dependent inact

146 Finally, pharmacokinetic investigations of a divalent GLP-1 analogue demonstrated a promising gain in

147 Importantly, divalent GLP-1 analogues showed efficacy comparable to l

148 In lean mice, the divalent GLP-1 analogues were superior to monovalent ana

149 scattering measurements, we postulated that divalent guest molecules 4/5 cover the curved vesicular

150 The resulting divalent inhibitor exhibits an in vitro inhibition const

151 , suggesting a greater reducible fraction of divalent inorganic Hg.

152 We find that divalent interaction of SAv with biotinylated surfaces i

153 Using a gating mutant at the divalent ion binding site, we were able to characterize

154 ely charged residues in the loop regions for divalent ion binding.

155 receptor potential melastatin 7 (TRPM7) is a divalent ion channel with a C-terminally located alpha-k

156 ikely to apply to other structurally similar divalent ion channels.

157 onformation as a function of either mono- or divalent ion concentration.

158 Changes in monovalent and divalent ion concentrations drive an abrupt switch betwe

159 ripping voltammetric current response to the divalent ion is enhanced to achieve a subnanomolar detec

160 ke and release, but in this case the primary divalent ion is Zn(2+) rather than Ca(2).

161 carried out a series of experiments to test divalent ion usage and preferences.

162 e resultant peak potentials of the secondary divalent ion vary with its sample activity to yield an a

163 lular Ca(2+) , suggesting that influx of the divalent ion via more Ca(2+) -permeable normal MT channe

164 binding to simple dsRNAs is not regulated by divalent ion, analysis of the interaction of the isolate

165 nnel of the trimeric Dut where it chelates a divalent ion.

166 als that the binding affinity is enhanced by divalent ion.

167 ity of Gfh proteins depends on the nature of divalent ions (Mg(2+) or Mn(2+)) present in the reaction

168 er selenide nanocrystals using two different divalent ions as guest cations (Zn(2+) and Cd(2+)) and c

169 Conversely, interactions with divalent ions can be used to tether headgroups in-plane,

170 Divalent ions counteract this decondensation effect by m

171 However, RED using feed streams containing divalent ions experiences lower power densities because

172 Divalent ions fulfill essential cellular roles and are r

173 nism, separate from fast adaptation, whereby divalent ions interacting with the local lipid environme

174 Divalent ions Mg(+2), Zn(+2), Co(+2), Hg(+2) and Cd(+2)

175 The specificity of this effect for different divalent ions suggests binding sites that are not an EF-

176 Necessity of the divalent ions to retain the suspension signified the ele

177 emerge from the binding energies of the six divalent ions with amino acids and dipeptides.

178 endence emphasizes the strong interaction of divalent ions with the membrane and its effect on the me

179 in and critically depends on the presence of divalent ions, consistent with results from small-angle

180 We found that extracellular divalent ions, including Ca(2+), inhibit the permeation

181 In the absence of divalent ions, NCS-1 unfolds and refolds reversibly in a

182 The presence of divalent ions, particularly calcium, appears to be an im

183 ch contain not only monovalent ions but also divalent ions.

184 to GO functional group bridging with NOM and divalent ions.

185 the presence of Mg(2+) and in the absence of divalent ions.

186 this transition was found to be enhanced by divalent ions.

187 ree of esterification and in the presence of divalent ions.

188 hysiological manganese substrate and similar divalents iron and cobalt, with several small amino acid

189 nthesized divalent M2pep with monovalent and divalent KLA ([M2pep]2-[KLA] and [M2pep]2-[KLA]2) to eva

190 The recently reported series of divalent lanthanide complex salts, namely [K(2.2.2-crypt

191 The reactions of the divalent lanthanide metallocenes [Cp*2Ln(thf)2] (Cp* = e

192 transport in the presence of high-abundance divalents like calcium and magnesium.

193 Here, we show that a divalent lupus anti-DNA autoantibody fragment with enhan

194 hatic endothelium by surface clustering with divalent LYVE-1 mAbs.

195 ation used was either monovalent (sodium) or divalent (M(2+)).

196 We next synthesized divalent M2pep with monovalent and divalent KLA ([M2pep]

197 agnesium-chloride bond and slow diffusion of divalent magnesium cations in cathodes.

198 presence of a lipid bilayer environment and divalent manganese cations.

199 d diacylglycerol, and full activity required divalent manganese.

200 be affected by the availability of inorganic divalent mercury (Hg(II)) and by the activities of Hg(II

201 Understanding the speciation of divalent mercury (Hg(II)) in aquatic systems containing

202 dentified as environments in which inorganic divalent mercury (Hg(II)) is transformed to methylmercur

203 Divalent mercury ion (Hg(2+)) is one of the most common

204 primarily because it is a highly competitive divalent metal and will displace more weakly bound trans

205 upper and lower recognition arm lengths, and divalent metal cation species and concentration.

206 BpsB can use a variety of divalent metal cations for deacetylase activity and show

207 Replicative DNA polymerases (DNAPs) require divalent metal cations for phosphodiester bond formation

208 encodes the ZIP8 protein which co-transports divalent metal cations, including heavy metal cadmium, t

209 two-step process: primary extraction using a divalent metal chelation disk followed by anion-exchange

210 that they exhibit a unique requirement for a divalent metal cofactor for enzymatic activity.

211 Additionally, essential and non-essential divalent metal content of human islets under normal envi

212 alyte, a peptide, and/or an amino acid and a divalent metal ion (for 16 different monosaccharide isom

213 1 is observed to directly chelate a hydrated divalent metal ion and Arg124, on the putative substrate

214 xperiment provides evidence for inner-sphere divalent metal ion coordination with a nucleobase.

215 efine the role of the newly discovered third divalent metal ion for DNA polymerase-catalyzed nucleoti

216 SLC39A8 encodes ZIP8, a divalent metal ion transporter best known for zinc trans

217 This is an enzyme with divalent metal ion(s) (Mg(2+) or Mn(2+)) in its catalyti

218 Two closely spaced divalent metal ions (catalytic and nucleotide-binding me

219 HNH nuclease domain, and identifying how the divalent metal ions affect the HNH domain conformational

220 ombinant hTPSTs are active in the absence of divalent metal ions and that optimal activity is at pH 6

221 Divalent metal ions are essential components of DNA poly

222 Moreover, divalent metal ions are required for the formation of te

223 We previously reported that divalent metal ions dictate the conformation of the extr

224 ions and the presence of other monovalent or divalent metal ions do not affect its detection ability.

225 lyze phosphoryl transfer reactions using two divalent metal ions in the active site.

226 entails chemotypes capable of chelating two divalent metal ions in the RNase H active site.

227 Other divalent metal ions including Ca(2+), Cd(2+), Zn(2+), Ni

228 When a large excess of divalent metal ions is absent, the charge is largely bal

229 When a large excess of divalent metal ions is present, the charge is predominan

230 Unlike the binding of other divalent metal ions such as Ca(2+) and Mg(2+) to PS, Cu(

231 rmed more stable duplexes in the presence of divalent metal ions than in the absence thereof, but wit

232 ngle-molecule junctions (M=Co, Ni, Cu, or Zn divalent metal ions), in which the current flows perpend

233 MOSCs), are constructed from the assembly of divalent metal ions, 1,4-benzenedicarboxylate (BDC) link

234 in the active site required the presence of divalent metal ions, a free 5'-flap (if present), a Wats

235 also exhibits high selectivity against other divalent metal ions, and the application of the sensor f

236 Synthetic supercontainers constructed from divalent metal ions, carboxylate linkers, and sulfonylca

237 an organic solid, is highly amenable to host divalent metal ions, i.e., Mg(2+) and Ca(2+), in aqueous

238 Among the other divalent metal ions, only Hg(2+) can cleave the substrat

239 is highly active at low pH in the absence of divalent metal ions, similar to eukaryotic DNase II.

240 l formation within 30 min in the presence of divalent metal ions.

241 a compact conformation in the absence of any divalent metal ions.

242 designing fluorescent sensors or probes for divalent metal ions.

243 d in the presence of Cu(II) but not by other divalent metal ions.

244 reaction without catalytic participation of divalent metal ions.

245 into insoluble spherical nanoparticles with divalent metal ions.

246 ivity of aqueous silver nanoparticles toward divalent metal ions.

247 led on a membrane surface in the presence of divalent metal ions.

248 The effect of this variant on the divalent metal profile in human islets is unknown.

249 For 8-oxo-dGTP(anti) insertion, a novel divalent metal relieves repulsive interactions between t

250 range of coordination environments, and the divalent metal site is crystallographically identified a

251 ot HIF-1alpha) or the downstream target gene divalent metal transporter (DMT)-1 in lactating mothers

252 opsis thaliana member of the NRAMP family of divalent metal transporters, NRAMP2, which functions in

253 jor iron transporters in the small intestine divalent metal-ion transporter 1 (DMT1) and ferroportin

254 cal membrane of the intestinal enterocyte by divalent metal-ion transporter 1 (DMT1) and is exported

255 Divalent metal-ion transporter 1 (DMT1) has been found t

256 vided by three isozymes known to rely upon a divalent metal.

257 her showed that both cleavage activities are divalent-metal-dependent and reside in the GGDD motif of

258 ile over-expression upregulates ferritin and divalent-metal-transporter-1 (DMT-1), indicating PrP(C)-

259 Cu (CTR1 and ATP7A), Na (NHE-2), Ca (ECaC), divalent metals (DMT1), and Zn (ZIP8) were also compared

260 e examined the correlation of zinc and other divalent metals in human islets with rs13266634 genotype

261 NMR measurements and MR imaging of multiple divalent metals in opaque biological samples.

262 In addition to divalent metals such as Ca(2+), Mg(2+), and Zn(2+), mono

263 tron-rich moieties are to be anticipated for divalent metals such as Ca(2+).

264 hat identify multiple biologically important divalent metals via metal-specific chemical shifts.

265 DNAzymes have been previously used to detect divalent metals, while no analytical work was carried ou

266 esence of zinc and cobalt but not with other divalent metals.

267 Divalent Mg(2+) showed no observable effect on anthocyan

268 permit efficient and reversible exchange of divalent Mg2+ cations to preserve charge storage capacit

269 During digestion, high concentrations of divalent minerals (DMs) can lead to insoluble lipid-soap

270 Furthermore, we found that a divalent model of antibody binding gives accurate K(d) a

271 ly improved using a tetravalent instead of a divalent molecule, since the tetravalent molecule can fo

272 Usually divalent molecules show enhanced biological activities t

273 a neutral state (L --> N-R) and the explicit divalent N(I) character (L --> N <-- L)(+) in the proton

274 se systems suggested the existence of hidden divalent N(I) character in a neutral state (L --> N-R) a

275 Donor-stabilized divalent N(I) systems have recently gained attention in

276 We observe that the divalent nature of Mg(2+) causes unique squeezing deform

277 The unique combination of a divalent organolanthanide fragment, Cp*2Yb, with bipyrim

278 in part, because of the stabilization of the divalent oxidation state.

279 d of urinary pigment uroerythrin coordinates divalent palladium as a planar tridentate ligand.

280 port cycle requires three Na(+) ions and one divalent Pi to bind before a conformational change enabl

281 rcury (GEM, Hg) emissions are transformed to divalent reactive Hg (RM) forms throughout the troposphe

282 extremely high salt concentrations and in a divalent salt environment.

283 At pH 7.0, the divalent salts resulted in weaker gels formed by agglome

284 modest (30-40%) retention of monovalent and divalent salts.

285 amine (DOPE), with the addition of mono- and divalent salts.

286 e cellulosome, whereby ScaG interacts with a divalent scaffodin (ScaA) that bears the enzymes either

287 tivated channels, eliminated the voltage and divalent sensitivity with minimal effects on adaptation.

288 rein, we investigated the effect of mono- or divalent small-molecule albumin binders for half-life ex

289 r than those elicited by Ca(2+) By combining divalent species interacting with unique sites, we demon

290 ehavior created by the onset of a metastable divalent state that starts at californium.

291 lly added to the suspensions remained in the divalent state, likely in the form of beta-HgS-like clus

292 these issues by analyzing the effects of the divalent strontium ion (Sr(2+)) on the voltage dependenc

293 can likely be generalized to other bioactive divalent trace metals.

294 n this motif serve as the binding site for a divalent transition metal cofactor [e.g., Fe(II) or Zn(I

295 ly transporters catalyze uptake of essential divalent transition metals like iron and manganese.

296 ent with previous measurements made on other divalent transition metals.

297 try determined solely by the identity of the divalent transition-metal ion (Fe(2+) or Ni(2+)) in the

298 While we previously only considered divalent ureidopyrimidinone monomers we now present a mo

299 y sensitive and selective sensing systems of divalent zinc ion (Zn(2+)) in organisms has been a growi

300 Chelatable, mobile forms of divalent zinc, Zn(II), play essential signaling roles in