ライフサイエンスコーパス: divergently

1 oward NAD and cADPR homeostasis have evolved divergently.

2 ted to a deuteriomethylated product, and can divergently access medicinally important motifs.

3 chondrial respiration in diabetic hearts was divergently activated following hypoxia compared with co

4 We now show that NIK binds to and divergently activates the plasma membrane Na(+)-H(+) exc

5 Thus, engagement of distinct FcgammaR can divergently affect cytokine production and susceptibilit

6 of EVI1 for efficient interaction, and they divergently affect the ability of EVI1 to regulate gene

7 The two groups of genes are transcribed divergently and separated by a regulatory region, which

8 This region, designated par, consists of two divergently arranged operons: parCBA and parDE.

9 euO promoter (pleuO) located between the two divergently arrayed ilvIH and leu-500 promoters.

10 sotocin (AVT) modulate fictive vocalizations divergently between three reproductive morphs.

11 These three product classes were accessed divergently by taking advantage of the electronic and st

12 Our work suggests that FlhG ATPases divergently evolved in each polarly flagellated species

13 point to a generic specificity mechanism in divergently evolved protein-protein interactions.

14 onserved residues in amino acid sequences of divergently evolved proteins are frequently observed; th

15 ved that proteins with promiscuous functions divergently evolved to acquire higher specificity and ac

16 es support the conclusion that all TGTs have divergently evolved to specifically recognize their cogn

17 l emergence of a new swine disease caused by divergently evolved viruses suggests that changes in swi

18 and dnaA genes contains five promoters that divergently express the ribosomal protein L34 and the pr

19 orting widespread functional compensation of divergently expressed duplicate genes by transcriptional

20 (AI) were used to identify 160 reliable and divergently fertile bulls for a dual strategy of targete

21 the protease (speB) and ropB are transcribed divergently from a 940-bp intergenic region.

22 ermobacter thermautotrophicus is transcribed divergently from a gene (designated trpY) that encodes a

23 ron, which we named arc, that is transcribed divergently from accR.

24 ahyR and asaR are transcribed divergently from ahyI and asaI, respectively, and in bot

25 500 base pairs in length and are transcribed divergently from cognate coding gene transcripts.

26 C genes form an operon and are cotranscribed divergently from ctrA.

27 Expression of the gltC gene, transcribed divergently from gltA from an overlapping promoter, was

28 ene located upstream of hmuR and transcribed divergently from it along with hmuTUV.

29 , a gene located upstream of and transcribed divergently from mexJK.

30 q detected short non-coding RNAs transcribed divergently from more than a thousand promoters in wild-

31 lthough RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive

32 t activator of the pdxST operon, transcribed divergently from pdxR and responsible for the de novo sy

33 bed another gene, ptxS, which is transcribed divergently from ptxR and interferes with the enhancemen

34 ng an Lrp-like protein was found transcribed divergently from putA.

35 ate kinase, is monocistronic and transcribed divergently from the idnD-idnO-idnT-idnR operon, which e

36 s have shown that mrpI, which is transcribed divergently from the mrp operon, encodes a recombinase c

37 terminal domain, and its gene is transcribed divergently from the operon that it regulates and is sub

38 pltR and pltM are transcribed divergently from the pltLABCDEFG gene cluster, and a seq

39 SMU.1349 is transcribed divergently from the rest of the genes encoded by the op

40 The gene encoding TamR is oriented divergently from the tam gene, which encodes trans-aconi

41 gene is located upstream and is transcribed divergently from the thrombospondin 3 (Thbs3) gene; 1352

42 The first three ORFs, oriented divergently from the traI-trb operon, are closely relate

43 Divergently grown dendrimers of the zero, first, second,

44 and black bream, express these old paralogs divergently in black- and clearwater habitats, while sti

45 ory nuclei may have evolved independently or divergently in phylogeny.

46 Two other RNAs encoded divergently in the yfhL-acpS intergenic region were simi

47 y is a distinctive individual trait that may divergently influence host biology.

48 trated that transcription of the operons was divergently initiated from adjacent start sites present

49 Upstream of tonB(Rl) and transcribed divergently is an operon, hmuPSTUV, whose products are h

50 a ketoreductase, and the four genes reading divergently, left to right, include two open reading fra

51 Among them, two genes, pkn5 and pkn6, are divergently located on the chromosome and share a 46 bp

52 ne expression were determined in mice having divergently low and high angiogenic responses.

53 of the molecule could be systematically and divergently modified.

54 receptors to phosphorylate and activate NHE1 divergently of its activation of JNK.

55 In summary, different alpha-Syn species act divergently on the axonal transport machinery.

56 at rlrA lies in a 12-kb pathogenicity islet, divergently opposed to three putative sortase-anchored s

57 nd -35 promoter elements of the overlapping, divergently orientated promoters of hifA and hifBCDE, wh

58 The genes (hagA and hagB) were adjacent and divergently oriented and had no orthologs in the genomes

59 um was shown to possess a closely linked and divergently oriented equivalents of the regulator of per

60 the AraC family was identified upstream and divergently oriented from bfeA.

61 in (GalR) encoded by the galR gene, which is divergently oriented from the structural genes of the ga

62 r xanthine dehydrogenase regulator (XdhR) is divergently oriented from xdhABC, which encodes xanthine

63 the intergenic regulatory region between the divergently oriented fucAO and fucPIK operons.

64 ified a regulatory gene (pvuIIC) between the divergently oriented genes for the restriction endonucle

65 e, DNGPs are significantly more likely to be divergently oriented on the chromosome; remarkably, appr

66 motifs within intergenic regions separating divergently oriented operons differs from the distributi

67 The transcriptional start sites for the divergently oriented phzA and phzR genes were mapped by

68 PIP-seq detected divergently oriented Pol II at both coding and noncoding

69 Two divergently oriented promoters, whiEP1 and whiEP2, were

70 ing a bidirectional promoter shared with the divergently oriented TADA2L, which encodes a component o

71 s are found together, closely juxtaposed and divergently oriented, at the locus of active transcripti

72 CDPGs, convergently-paired genes or CPGs and divergently-paired genes or DPGs) and three patterns (se

73 the C10-C11 diastereomers of cytostatin was divergently prepared (11 steps from key convergence step

74 ssion of PU.1, encoded by the Sfpi1 gene, is divergently regulated by Ikaros in distinct cell type-sp

75 In wild-type macrophages, TZD treatment divergently regulated CD36 and class A macrophage-scaven

76 Divergently regulated genes were associated with a large

77 Divergently regulated orthologues were enriched for gene

78 mice (24% of orthologues were identified as "divergently regulated").

79 myoblasts and find that their expression is divergently regulated.

80 iments revealed that decreasing Trpm4 levels divergently regulates nuclear localization of NFATc1.

81 Groups of divergently related enzymes whose members catalyze diffe

82 Other groups of divergently related enzymes whose members catalyze diffe

83 ) and V(L) complexity appears to be evolving divergently, retaining diversity in V(L) perhaps to comp

84 A long-established inbred strain of mice was divergently selected for body weight for 50 generations.

85 es of microsatellite marker alleles in lines divergently selected for body weight from a base populat

86 anges during seed development in populations divergently selected for large and small seed size from

87 d in lines of Large White pigs that had been divergently selected on the basis of lean growth efficie

88 used to discriminate between lines of pigs, divergently selected over seven generations for componen

89 pairs) and 2 from a California population (1 divergently selected pair).

90 luding 10 from a Massachusetts population (5 divergently selected pairs) and 2 from a California popu

91 at surprisingly large genomic regions around divergently selected quantitative trait loci can be prot

92 equence upstream of the leukotoxin operon is divergently shared by P(lapT), which transcribes an argi

93 ver, genotypes responded to the environments divergently so that two populations displayed similar di

94 mouse, maternally contributed methylation is divergently targeted to species-specific sets of CpG isl

95 hnAB and phnR operons, which are transcribed divergently; the resulting mRNAs overlapped by 29 nucleo

96 signals for the two Ti plasmids have evolved divergently through changes in the opine synthase enzyme

97 cturally homologous bacterial toxins evolved divergently to bind calmodulin, an evolutionarily conser

98 Adjacent but transcribed divergently to sarT is sarU, which encodes a 247-residue

99 a single gene at the left end is transcribed divergently towards the telomere, and a tRNA gene separa

100 h UL37 glycoprotein cleavage products, which divergently traffic either through the secretory apparat

101 UL37) is internally cleaved and its products divergently traffic to mitochondria or are retained in t

102 ix identifiable genes organized as two units divergently transcribable from a 258-bp inter-genic regi

103 dentified the ToxT binding sites between the divergently transcribed acfA and acfD genes, which encod

104 contrast to what we previously found for the divergently transcribed acfA and acfD genes, which share

105 rylation events, leading to induction of the divergently transcribed agrBDCA operon and the RNAIII ge

106 R binding site in the promoter region of the divergently transcribed ahpC gene.

107 lon genes such as nodABC, syrM and nodD3 are divergently transcribed and are separated by approximate

108 The omlA and fur genes were divergently transcribed and had overlapping promoter reg

109 ed at 53.0 min on the E. coli chromosome, is divergently transcribed and is separated by 206 bp from

110 man Surf-1 and Surf-2 housekeeping genes are divergently transcribed and share a bi-directional, TATA

111 ase PCR analyses show that hutA and tonB are divergently transcribed and that the remaining hut genes

112 tructure, within which dehI and dehR(I) were divergently transcribed and were flanked on either side

113 immediately upstream, phaR, -B, and -C were divergently transcribed as a tricistronic operon.

114 sion of the Gng3 gene, but expression of the divergently transcribed Bscl2 gene is not affected.

115 . enterocolitica psp locus is made up of two divergently transcribed cistrons, pspF and pspABCDycjXF.

116 cond operon that is upstream of bssDCABE and divergently transcribed contains two genes, tdiS and tdi

117 We suggest that basic building blocks of divergently transcribed core promoter pairs, in combinat

118 er with the genomic region that includes the divergently transcribed D. grimshawi DgYp1 and DgYp2 gen

119 ctional promoters regulate expression of the divergently transcribed dihydrofolate reductase (dhfr) a

120 pt abundance is coregulated with that of the divergently transcribed DPB3 gene, which codes for a sub

121 vary gland polytene chromosomes contains the divergently transcribed E63-1 and E63-2 ecdysone-inducib

122 This R-M system comprises divergently transcribed endonuclease (llaKR2IR) and meth

123 ate that MsvR regulates transcription of the divergently transcribed fpaA-rlp-rub operon in Methanoth

124 The human GPAT and AIRC genes are divergently transcribed from a 558 bp intergenic promote

125 The potABCD operon is divergently transcribed from a promoter near pepT P2.

126 odes a LysR-type transcription factor and is divergently transcribed from a promoter overlapping that

127 a tested, including M. tuberculosis, oxyR is divergently transcribed from ahpC, a gene encoding a hom

128 In both species, oxyR is divergently transcribed from ahpC, which encodes a homol

129 ed as part of the lsrACDBFG operon, which is divergently transcribed from an adjacent lsrRK operon.

130 e clinical isolates by mecR1 and mecI, genes divergently transcribed from mecA that encode a signal t

131 criptional units (prpR and prpBCDE) that are divergently transcribed from one another.

132 e is closely linked to the psp operon and is divergently transcribed from one major and two minor sig

133 Divergently transcribed from pigS-pmpABC is a bicistroni

134 ly downstream of the prpBCDE operon; hemB is divergently transcribed from prpBCDE and is separated fr

135 d capsule biosynthesis (synABCD) operons are divergently transcribed from putative promoters located

136 Three open reading frames, divergently transcribed from the 4-hydroxybenzoate coenz

137 le of IcaR, encoded within the ica locus but divergently transcribed from the biosynthetic genes.

138 l activator, CbbR, encoded by cbbR, which is divergently transcribed from the cbbLS genes (encoding f

139 Divergently transcribed from the che3 promoter region is

140 1 gene, which is immediately adjacent to and divergently transcribed from the cif-containing, three-g

141 The fliX gene is located upstream and is divergently transcribed from the class III flagellar gen

142 An open reading frame just upstream and divergently transcribed from the fimA operon was identif

143 egulator (gene PA2082, here called kynR), is divergently transcribed from the kynBU operon and is hig

144 cl/GalR family of repressor proteins, and is divergently transcribed from the malEFG gene cluster, wh

145 le L-lactate dehydrogenase (ldh1, SACOL0222) divergently transcribed from the NO.-detoxifying flavohe

146 s and also that the LysR-type regulator AlsR divergently transcribed from the operon is required for

147 65c (designated Mce1R), lies upstream and is divergently transcribed from the operon.

148 CA0909) and hutX (ORF VCA0908), in an operon divergently transcribed from the tonB1 operon.

149 Divergently transcribed from this gene cluster is the ge

150 Divergently transcribed from yqjH is the yqjI gene, whic

151 he benM gene is immediately upstream of, and divergently transcribed from, benA, and a possible DNA b

152 ncoded in the frzA-F putative operon and the divergently transcribed frzZ gene.

153 a-aminobutyric acid (GABA) and represses the divergently transcribed gabR gene.

154 sence, in the flanking upstream region, of a divergently transcribed gene (phhR) encoding an activato

155 found that OxyR2 is required to activate its divergently transcribed gene ahpC, encoding an alkylhydr

156 The divergently transcribed gene gxyR encodes a repressor of

157 by Ape1, an AraC-type regulator encoded by a divergently transcribed gene immediately upstream of PI-

158 of kayak (kay) and fos intron gene (fig), a divergently transcribed gene located in a kay intron, ut

159 tween 23,752 genes, we identified a class of divergently transcribed gene pairs, representing more th

160 genes (L71 genes) that are organized as five divergently transcribed gene pairs.

161 e H2A and two for histone H2B located in two divergently transcribed gene pairs: HTA1-HTB1 and HTA2-H

162 ted genetic evidence that SgrR activates the divergently transcribed gene sgrS, which encodes a small

163 We also identified a divergently transcribed gene that regulates cdsH express

164 The function of the upstream, divergently transcribed gene yhcS, encoding a regulatory

165 The product of the divergently transcribed gene, b1013, is a tetracycline r

166 lor A3(2) and was found to lie adjacent to a divergently transcribed gene, scbR, which encodes a gamm

167 GltC, a LysR-family protein, encoded by the divergently transcribed gene.

168 One region in the promoter of the divergently transcribed genes aflR/aflJ bound weakly to

169 gion encompasses the upstream regions of two divergently transcribed genes and contains a sequence mo

170 We show that these divergently transcribed genes are regulated by LexA prot

171 core Mga regulon and Mga is able to activate divergently transcribed genes from a single site.

172 ts performed in L. brevis confirmed that the divergently transcribed genes LVIS1988, LVIS1987 and LVI

173 acfA and acfD are divergently transcribed genes required for efficient col

174 aldA and tagA are divergently transcribed genes that also have unknown rol

175 dE2F2/dREAM binding sites are enriched at divergently transcribed genes, and the majority of genes

176 rk from regulatory sites located between the divergently transcribed genes, are weak.

177 e simocyclinone biosynthetic cluster are two divergently transcribed genes, simR and simX, encoding p

178 H3K36me2 is scarce in regions upstream of divergently transcribed genes, telomeres, silenced matin

179 evealed that this DNA fragment contained two divergently transcribed genes, tetA and tetR, encoding p

180 ying CpG islands that overlap the 5' ends of divergently transcribed genes.

181 The adjacent, divergently transcribed glpACB and glpTQ operons of Esch

182 located between, and transcription from, the divergently transcribed H3-H4 genes nucleates HLB format

183 chromosome 12q13.13, 589 bp upstream of the divergently transcribed hnRNPA1 gene.

184 operon, which is negatively regulated by the divergently transcribed icaR gene.

185 nstrate transcriptional coupling between the divergently transcribed ilvY and ilvC promoters of the i

186 Eukaryotic promoter regions are frequently divergently transcribed in vivo, but it is unknown wheth

187 Upstream of the sitABC operon and divergently transcribed lies a 645-bp open reading frame

188 We propose that the RNA exosome protects divergently transcribed lncRNA expressing enhancers by r

189 The divergently transcribed lncRNA/mRNA gene pairs exhibit c

190 Moreover, we see that divergently transcribed lncRNAs do not always correlate

191 The additional presence of an adjacent divergently transcribed locus, rorA (rlrA override), whi

192 ogt; these genes may be regulated by AbgR, a divergently transcribed LysR-type protein.

193 and possibly ogt and might be regulated by a divergently transcribed LysR-type regulator encoded by a

194 mined the behavior of two promoters from the divergently transcribed M. tuberculosis genes acr/hspX/R

195 ned the initiation point of a less abundant, divergently transcribed message (from prgX).

196 se Thbs3 is located just downstream from the divergently transcribed metaxin gene (Mtx), which encode

197 Previous work has shown that the divergently transcribed Mycobacterium tuberculosis genes

198 II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA.

199 S. Typhimurium-encoded orthologues of two divergently transcribed OmpR-regulated operons (SL1068-7

200 esults reveal differential regulation of the divergently transcribed ooc transcriptional units, highl

201 on revealed a 282-bp intergenic region and a divergently transcribed open reading frame, designated p

202 the isolation of mutations in two adjacent, divergently transcribed open reading frames (eri-6 and e

203 onal coupling between the promoters of other divergently transcribed operons is investigated, additio

204 gment encoding five genes, parCBA/DE, in two divergently transcribed operons promotes stable maintena

205 anized as two subclusters, consisting of two divergently transcribed operons, rbr-fprA-hrb and rbo-ru

206 he catabolic activities are localized to two divergently transcribed operons, the siaPT operon and th

207 more distal 5' sites that also regulate the divergently transcribed ORF45-ORF46-ORF47 gene cluster.

208 entified a second histone H4 gene (hH4-2), a divergently transcribed pair of genes that encode H2A an

209 epressed half of a differentially expressed, divergently transcribed pair of genes.

210 20-nucleotide intercistronic region with the divergently transcribed pbp4 gene, which encodes the tra

211 moter and regulatory regions of fimA and the divergently transcribed pepO gene, which encodes a zinc

212 BP 1, while repressing the expression of the divergently transcribed pilM gene, the first gene in the

213 ch zone was in the CpG island containing the divergently transcribed promoter separating the DHFR and

214 nerated in the region between closely spaced divergently transcribed promoters could serve to couple

215 thylation-free CpG islands spanning the dual divergently transcribed promoters from the human TATA bi

216 transcriptional coupling that occurs between divergently transcribed promoters is likely to serve a p

217 ation-free CpG islands associated with dual, divergently transcribed promoters possess an independent

218 NA supercoiling can be generated between two divergently transcribed promoters.

219 s, exosome is also significantly enriched at divergently transcribed promoters.

220 or, PigZ, which represses transcription of a divergently transcribed putative resistance-nodulation-c

221 r extension analysis to demonstrate that the divergently transcribed regB and senC-regA-hvrA transcri

222 carboxylase oxygenase (RubisCO) along with a divergently transcribed regulator gene, cbbR.

223 , was cloned and shown to be adjacent to and divergently transcribed relative to the putative ABC-typ

224 d between defined enhancers and placed among divergently transcribed reporter genes (white and lacZ)

225 e complexes containing modular promoters and divergently transcribed reporter genes.

226 ading frames, arranged in three measured and divergently transcribed RNAs.

227 ate the raffinose-dependent stimulation of a divergently transcribed second promoter (P(A)) directing

228 ified, one of which was shown to contain the divergently transcribed solR and solI genes, the luxR an

229 promoters for the spuABCDEFGH operon and the divergently transcribed spuI gene of unknown function.

230 ively regulates the transcription of its own divergently transcribed structural gene in an inducer-in

231 tream Egr2 binding sites lie proximal to the divergently transcribed succinate dehydrogenase C gene,

232 contains the oriT site and the two flanking, divergently transcribed tra operons that encode the DNA

233 esignated cbbRRS, are juxtaposed between the divergently transcribed transcription activator gene, cb

234 r, we report the nucleotide sequences of two divergently transcribed transcriptional units.

235 within open reading frames (33%) and between divergently transcribed transcripts (5%).

236 into a plasmid-borne target site between two divergently transcribed tRNA genes.

237 dicated that this region is expressed as two divergently transcribed units.

238 pe transcriptional regulatory gene, ceoR, is divergently transcribed upstream of the structural gene

239 ral and accessory genes (ureDABCEFG) and the divergently transcribed ureR, which codes for an AraC-li

240 e operon, and increases transcription of the divergently transcribed ureR.

241 1.2-kb Fab-7 DNA fragment was placed between divergently transcribed white and lacZ test promoters an

242 show that SET domain-containing 5 (Setd5) is divergently transcribed with Gt(ROSA26)Sor, is necessary

243 The LEE2 and LEE3 operons are divergently transcribed with overlapping -10 promoter re

244 Null mutations in gabT, gabD or the divergently transcribed ycnF (gabR) gene blocked the uti

245 The fimB gene is separated from the divergently transcribed yjhATS operon by a large (1.4 kb

246 Both the ytmI operon and the divergently transcribed ytlI, encoding a LysR-type regul

247 NLVCF and HIRA are divergently transcribed, and their start codons lie appr

248 B and tagDEF operons, which are adjacent and divergently transcribed, encode genes responsible for ce

249 oxyR and dps were found to be divergently transcribed, with an overlap in their respec

250 and Mkbp/HspB2 genes are closely linked and divergently transcribed.

251 III flagellar genes, fliL-flgF, that is also divergently transcribed.

252 eron, with the potABCD operon and cobB being divergently transcribed.

253 egions of the ospC and guaA genes, which are divergently transcribed.

254 (zif) are adjacent on the chromosome and are divergently transcribed.

255 ontain documented promoters or occur between divergently transcribing coding regions, and hence may b

256 which all three family members were accessed divergently via palladium-catalyzed reactions.

257 uctural platform from which proteins evolved divergently, with some losing inhibitory functions.

258 n initiation point analysis and found to map divergently within and near an AT-rich element flanked b