ライフサイエンスコーパス: diverse

1 mic and genetic etiological bases of RLS are diverse.

2 p generated through genome sequencing of 117 diverse accessions.

3 3CA mutations or PTEN deletion to grow using diverse amino acid sources.

4 kely to have CVM dominated by L. iners or by diverse anaerobic bacteria, than by L. crispatus.

5 ion of tools has been developed that perform diverse analyses using VCF files.

6 hese various surfaces toward the analysis of diverse analytes.

7 or illuminating the molecular basis of their diverse and complex roles in a wide array of biological

8 These data describe the isolation of diverse and efficacious antitoxin mAbs.

9 Halogenated natural products constitute diverse and promising feedstock for molecular pharmaceut

10 been observational, that are larger and more diverse and that embrace larger spatial and temporal sca

11 ter of some phenomena and explain the highly diverse and unpredictable magnitude of the total errors.

12 ores based on BSA were derived from a large, diverse, and healthy North American population.

13 properties of these materials are, however, diverse, and the molecular characteristics that permit c

14 ted tomography of dehydrating leaves of four diverse angiosperm species showed that, at the turgor lo

15 confer multidrug resistance by transporting diverse antibiotics from the cell.

16 em, providing versatile scaffolds to display diverse antigen-binding surfaces.

17 of chemists for a long time in view of their diverse applications in catalysis; as anion, cation, and

18 This approach may find diverse applications in microbiology and in biomedical a

19 Despite its very diverse applications, the core of tomography remains the

20 rm emission from soil has been reported from diverse Arctic, temperate, and (sub)tropical ecosystems.

21 as transitioned to greater prominence across diverse areas of biology and medicine.

22 The realization of QIP would transform diverse areas of research including accurate simulation

23 mpor-tant for remote sensing applications in diverse ares, such as nuclear nonproliferation, environm

24 nd disubstituted malononitriles, providing a diverse array of beta-ketonitriles.

25 ing proteins such as protein kinases adopt a diverse array of conformations to respond to regulatory

26 Neural crest cells give rise to a diverse array of derivatives including neurons and glia

27 ction sequences to provide rapid access to a diverse array of different heterocyclic as well as carbo

28 pot, implicated in infections, but also in a diverse array of diseases such as systemic lupus erythem

29 Herein we show in a diverse array of human cancer cells that IMP2 overexpres

30 rategy to enhance nanoparticle delivery to a diverse array of molecularly distinct target cells.

31 These data have opened the window to a diverse array of novel targets whose potential efficacy

32 We discuss the diverse array of reactions available involving omega-TAm

33 Filamentous fungi produce a diverse array of secondary metabolites (SMs) critical fo

34 Bacteria produce a diverse array of secondary metabolites that have been in

35 gical processes through phosphorylation of a diverse array of substrates.

36 nanobodies have been evolved to recognize a diverse array of targets, including a short peptide.

37 amination and hydroxylation of structurally diverse aryl- and heteroarylmetals.

38 on because of its involvement in diseases as diverse as cancer and neurological disorders.

39 tion, and basis by which cytokinin regulates diverse aspects of growth and development as well as res

40 Adult height has shown directionally diverse associations with several age-related disorders,

41 Researchers from diverse backgrounds can easily visualize, query, and exp

42 this mode of proliferation is widespread in diverse bacterial lineages, the underlying mechanisms ar

43 presentative whole-genome data sets from six diverse bacterial species: Staphylococcus aureus, Strept

44 Cultural relativism fosters tolerance of diverse beliefs and behaviors by forbidding judgment on

45 To characterize diverse belowground strategies in relation to species co

46 ed by two chemically and pharmacodynamically diverse beta-adrenoceptor agonists, isoproterenol and sa

47 lycoside hydrolase family 3 (GH3) members on diverse beta-glucans.

48 2] annulation tactic for the construction of diverse bicyclic compounds possessing highly functionali

49 messengers and cofactors that help regulate diverse biochemical processes such as transcription and

50 These findings suggest that diverse biologic exposures, including allergens and endo

51 ial for understanding the molecular basis of diverse biological events and important in drug developm

52 RNAs and RNAi pathways in the regulation of diverse biological functions.

53 G protein-coupled receptors (GPCRs) control diverse biological processes and are of great clinical r

54 ns have been implicated in the regulation of diverse biological processes by phosphorylation-dependen

55 These targets regulated diverse biological processes including nutrient sensing

56 regulation of actin cytoskeleton dynamics in diverse biological processes.

57 genetic modifications play critical roles in diverse biological processes.

58 Continued refinement to the model to reflect diverse biological systems and tissue types will further

59 ls, specifically: partition coefficients for diverse biotic media and passive sampler phases; aquatic

60 in small and unique subsets of neurons from diverse brain regions.

61 mode MS, included 44 authentic whiskies from diverse brands and batches and 44 counterfeit samples of

62 lysaccharides collected from 331 genetically diverse Brassica napus cultivars and used them to obtain

63 Our results show how NFkappaB sustains diverse cancer phenotypes via distinct classical and alt

64 Future directions are imagined, where the diverse capabilities laid out are combined and advances

65 scovery of N-confused porphyrins, remarkably diverse carbaporphyrinoid systems have been synthesized

66 s amine catalysis to promote mechanistically diverse carboligations.

67 enome mutation landscape of melanoma reveals diverse carcinogenic processes across its subtypes, some

68 rs affords multivariate correlations for two diverse catalytic systems with unique non-covalent inter

69 eyes form through coordinated integration of diverse cell fates across developmental space and time,

70 be used for fast phenotyping of functionally diverse cell populations with reasonable accuracy and wi

71 act that previous work has not distinguished diverse cell types in the neocortex, even though differe

72 toolkit to study MT dynamics and function in diverse cells.

73 tions, and responses of immune cells produce diverse cellular ecosystems composed of multiple cell ty

74 uitous intracellular messenger that controls diverse cellular functions but can become toxic and caus

75 Proteins have evolved to perform diverse cellular functions, from serving as reaction cat

76 that different gene mutations induce DCM via diverse cellular pathways.

77 Our analysis revealed diverse cellular processes, including the unfolded prote

78 dence for the versatility of CCPs to control diverse cellular processes.

79 nd to have a broad role in gene induction in diverse cellular responses, particularly throughout the

80 ionally diverse chimeras from three sequence-diverse channelrhodopsins (ChRs).

81 l (PO) and canola oil (CO), and compared for diverse chemical components and sensorial attributes, ai

82 analogs, thereby enabling screens in a much diverse chemical space.

83 synthesize past DNA adducts that result from diverse chemicals, reactive oxygen species or UV light.

84 86 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age range, 9.4-1

85 nation to create a large set of functionally diverse chimeras from three sequence-diverse channelrhod

86 R/Cas9 genome editing of promoters generates diverse cis-regulatory alleles that provide beneficial q

87 we demonstrate effectiveness of Hetero-RP in diverse clustering and classification applications.

88 ffort employed novel strategies to recruit a diverse cohort, and collected biological and environment

89 roughput DNA sequencing of microbiota from a diverse collection of fecal samples obtained from 11 typ

90 Using a conformationally diverse collection of natively folded and mutation-induc

91 In the past, this diverse collection of sequences from human as well as mo

92 Here we show that very diverse communities could persist thanks to the stabiliz

93 Among 3 diverse community-based cohorts, CKD was associated with

94 Single units coded for diverse conjunctions of variables, with different dimens

95 Recent studies have shown diverse connectivity patterns across the thalamus, but w

96 2002 to provide the largest, most population-diverse consideration of this hypothesis to date.

97 Picornaviridae and Parvoviridae were highly diverse, consisting of multiple genera, species, and gen

98 sses on networks is of prime significance in diverse contexts, ranging from the identification of "in

99 Herein, we address the diverse contributions of several recombination/repair pr

100 Muller glia play diverse, critical roles in retinal homeostasis, which ar

101 lar physiological platforms that incorporate diverse cues from the myocardial microenvironment are ex

102 cture in situ and integrate information from diverse data streams [1].

103 Co-expressing ectopic SoxN with svb rescued diverse denticle morphologies.

104 PIbalpha is required for injury responses in diverse disease models.

105 enhances the misreplication of structurally diverse DNA lesions.

106 ATEMENT Cerebellar systems are implicated in diverse domains of sex-biased behavior and pathology, bu

107 efficiency, low costs, and applicability for diverse downstream microbiological and molecular analyse

108 he use of this framework through a series of diverse ecological examples.

109 bioactive derivative of vitamin A, exhibits diverse effects on gene transcription and non-genomic re

110 to neuronal death in hippocampal neurons via diverse effects on NADPH oxidase activity and dendritic

111 Then, we cluster these diverse ensembles to identify the most diverse partition

112 al regulator of cell growth that responds to diverse environmental signals and is deregulated in many

113 al signatures in DCs in vivo, reflecting the diverse environments in which Th2 immune responses are i

114 Longitudinal follow up of birth cohorts in diverse environments worldwide will continue to provide

115 d Verstraetearchaeota are distributed across diverse environments.

116 Insight regarding how diverse enzymatic functions and reactions have evolved f

117 Although the NHS workforce is very diverse, ethnic minorities are unevenly spread across oc

118 Thus, proteomic profiling of cilia from diverse eukaryotes defines a conserved ciliary proteome,

119 yet rigorous and reproducible assays against diverse examples of this variable virus.

120 ding cell lines to organize and describe the diverse experimental variables and data resided in the E

121 methylamine-N-oxide), thus in effect linking diverse exposures such as those from dietary intake and

122 g network states in response to multiple and diverse external demands.

123 L) was recurrently found in three ethnically diverse families with an autosomal dominant mode of inhe

124 Tomography has made a radical impact on diverse fields ranging from the study of 3D atomic arran

125 nature of bioinformatics, many students from diverse fields struggle with grasping bioinformatic conc

126 Using research and QI projects allowed diverse findings to expand each other and identify gaps

127 lity is to participate in additional or more diverse fisheries.

128 tercept uncooperative targets is key to many diverse flight behaviors, from courtship to predation.

129 A cross-site analysis was conducted on seven diverse, forested watersheds in the northeastern United

130 hreonine kinases play a pathological role in diverse forms of malignancies, including multiple myelom

131 The evolutionary history of the old, diverse freshwater shrimp genus Caridina is still poorly

132 inally important heterocyclic scaffolds with diverse functional group tolerance.

133 at the majority of multi-exon genes generate diverse functional products, it is important to evaluate

134 P, orthophosphate, and pyruvate and provides diverse functions in plants.

135 PK and Stau1, further supports the protein's diverse functions in RNA metabolism and DNA maintenance,

136 ire ABC transporter superfamily and the many diverse functions it supports.

137 TrkC diverse functions might be attributed to the hypothetica

138 Different MAbs showed diverse functions that did not correlate with each other

139 re familiar, conspicuous and morphologically diverse Fungi.

140 biology is the stability of phenotype under diverse genetic and/or environmental perturbations.

141 We adopt the design to diverse GPCRs that sense a broad spectrum of ligands, in

142 The zauPzapA operon is present in diverse Gram-negative bacteria, indicating a common mech

143 st, inflammatory cardiomyopathies refer to a diverse group of disorders in which inflammation of the

144 i/o protein family transduces signals from a diverse group of G protein-coupled receptors (GPCRs).

145 Attendees were a diverse group of internationally recognized leaders in b

146 In May 2017, a diverse group of scientists assembled at the EMBO/EMBL S

147 tralization profiles of 12 human NAbs across diverse HCV strains, assigning the NAbs to two functiona

148 idation and glycoxidation protein targets in diverse heated milks.

149 he course of evolution by the recruitment of diverse host proteins that became major virion component

150 nd optimize humoral responses in genetically diverse human populations, with immediate implications f

151 ines and animal models representative of the diverse human STS subtypes critical.

152 ortant roles in directing the development of diverse immune cells and controlling the dynamic transcr

153 simultaneously in living tumors and across a diverse immunocompetent patient population may provide a

154 By contrast, the Detarioideae is much more diverse in Africa than in South America and Asia.

155 eive input from a variety of sources and are diverse in their physiology, structure, and gene express

156 a "dirty" mouse model that better mimics the diverse infectious history that is typical of most human

157 -reactive T cells in children to genetically diverse influenza A virus (IAV) strains to which the chi

158 wasps, ants, and bees) are one of four mega-diverse insect orders, comprising more than 153,000 desc

159 Diverse interpretations of Ediacaran organisms arise not

160 er results in the linear sorting of a set of diverse isogenic female lines, unambiguously demonstrati

161 structural homology with other sequentially diverse KA1 domains.

162 cts (60%), and cereals (56%) are produced in diverse landscapes (H>1.5).

163 Diverse late transition metal catalysts convert terminal

164 h structurally, chemically, and functionally diverse ligands modulate GPCR function.

165 ommon ancestor of humans and chimpanzees had diverse lineage III KIR that passed on to chimpanzees bu

166 r distribution with LDs may be linked to the diverse lipid storage in muscle between trained and sede

167 Among this cohort of racially diverse low-income patients hospitalized with HF, an app

168 resulted in identifying the epitope maps of diverse mAbs and the disulfide connectivity underlying E

169 s may perturb the regulatory network through diverse mechanisms including chromatin looping.

170 ew opportunities for applications built upon diverse membrane protein functions, or involved with dru

171 In addition, the diverse microbes that associate with corals have the cap

172 while interacting with a dense and extremely diverse microbial population.

173 al colonic inflammation, which led to a less-diverse microbiome and loss of protective gut commensal

174 side hydrolases can exhibit activity against diverse microorganisms and may be useful as therapeutic

175 well above 10 mum in diameter and contains a diverse mixture of potentially hazardous constituents an

176 opulations and recombination events in these diverse mixtures.

177 These findings suggest that signals from diverse modes of injury converge on p38alpha mitogen-act

178 Diverse molecular mechanisms regulate synaptic compositi

179 rtical inhibitory neurons exhibit remarkably diverse morphology, physiological properties and connect

180 imate marginalization by taking advantage of diverse multisensory representations.

181 The diverse nAChRs represent distinguishable drug targets wi

182 e relevant to the aetiology and treatment of diverse neurological and psychiatric diseases that are c

183 dance and escape in patients presenting with diverse neurological problems.

184 The mammalian brain contains diverse neuronal types, yet we lack single-cell epigenom

185 e state of the art of the field by showing a diverse number of recent highlights, including out-of-eq

186 Diverse online transformations, in which the substrate a

187 sense single-stranded, were classified into diverse orders/families.

188 Diverse organisms secrete redox-active antibiotics, whic

189 milarities, together with a dispersed set of diverse 'outlier' sequences.

190 ectins were able to mediate the binding of a diverse panel of gp120 proteins to alpha4beta7 in an in

191 des in the dauer-like infective juveniles of diverse parasitic nematodes, suggesting the antiparasiti

192 these diverse ensembles to identify the most diverse partition functions for Boltzmann stochastic sam

193 universal immune defense mechanism targeting diverse pathogens replicating in cytosolic membrane stru

194 of MEI production from source elements, (2) diverse patterns of MEI inheritance, and (3) the introgr

195 We detected diverse patterns of MEI stratification across these popu

196 nducible cell line, contain cell clones with diverse permissiveness to HBV replication.

197 This group of molecules, having diverse pharmacological activities, may be the basis for

198 Litchi seed extracts have diverse pharmacological effects, including anticancer.

199 e expressed fluorescent fusions of FtsZ from diverse photosynthetic organisms in a heterologous syste

200 udied systems lack a complete picture of how diverse physical and chemical cues act upon individual c

201 e, and further envision its universality for diverse physical systems.

202 are auxin-sensitive repressors that mediate diverse physiological and developmental processes in pla

203 Phylogenetic analysis of SNAP genes from 22 diverse plant species showed that SNAPs were distributed

204 ney is generated by various bee species from diverse plants, and because the value of different types

205 ct the cancer type in non-TCGA datasets from diverse platforms.

206 the biological functions supported by these diverse polypeptides require them to have an amphipathic

207 Monocytes are a diverse population of cells (classical, intermediate, an

208 sity with residential density in a large and diverse population sample drawn from the UK Biobank to i

209 ithin their hosts, they exist as genetically diverse populations (i.e., viral mutant swarms), which a

210 ut structural and molecular profiling of the diverse populations of synapses that compose those netwo

211 h excellent efficacy across genotypes and in diverse populations.

212 50 000 trees sourced from 116 geographically diverse populations.

213 ts highlight the importance of maintaining a diverse portfolio of urban green spaces and plant commun

214 y thymic progenitors (ETPs) are endowed with diverse potencies and can give rise to myeloid and lymph

215 changes in clinical practice as well as the diverse presentation of intestinal melanoma metastases a

216 IDO has been implicated in diverse processes in health and disease but its role in

217 ll-defined cell surface markers specific for diverse progenitor populations.

218 ease phenotypes, and identify 43 genetically diverse progeny by typing with microsatellites and 9230

219 a key component of the respiratory chain of diverse prokaryotic species, including pathogenic bacter

220 teins is a commonly conserved feature across diverse protein families (reviewed in [2]), including th

221 Diverse protein import pathways into mitochondria use tr

222 ed by immunoglobulin (IG) genes are the most diverse proteins expressed in humans.

223 mprovements have been assessed over a set of diverse proteins.

224 f 5172-mcP1P3 were designed by incorporating diverse quinoxalines at the P2 position that predominant

225 oinformatics training for individuals from a diverse range of academic backgrounds.

226 a membranes and endomembranes, and mediate a diverse range of biological processes.

227 elivered a number of novel findings across a diverse range of diseases, including age-related macular

228 Recombinant MpnEf-Tu bound strongly to a diverse range of host molecules, and when bound to plasm

229 Insects exhibit a fascinating and diverse range of micro- and nanoarchitectures on their c

230 mphipathic nature, and this is achieved by a diverse range of molecular structures, with some protein

231 clathrin-mediated endocytosis (CME) across a diverse range of organisms and mechanical environments s

232 ctivity becomes increasingly optimized for a diverse range of predicted dynamics in development.

233 replicate efficiently in a phylogenetically diverse range of species.

234 e populations that likely were caused by (1) diverse rates of MEI production from source elements, (2

235 enzymes are widely distributed and catalyze diverse reactions.

236 erall, the Midas cichlid has one of the most diverse repertoires of MHC class IIB genes known, which

237 adly fungal metabolism, has implications for diverse research disciplines ranging from plant patholog

238 te structures and G-rich sequences, ahead of diverse reverse transcriptases can be strong stimulators

239 of inhibitory interneuron are known to shape diverse rhythmic activities in the cortex, but how they

240 rotein that recognizes U/AU-rich elements in diverse RNAs through two RNA-recognition motifs, RRM1 an

241 ndings reveal that PDGFRalpha+ cells perform diverse roles in CNS repair, as multipotential progenito

242 methylation may vary in specific RE and play diverse roles in disease development, thus averaging met

243 Sema3 subfamily of signaling molecules plays diverse roles in the regulation of cell proliferation, m

244 n containing 1) was previously shown to have diverse roles in X-chromosome inactivation, imprinting a

245 prion-seeded amyloid formation highlight the diverse roles lipid constituents may play in the prion c

246 orary review first strives to understand the diverse roles of immune cells implicated in atherogenesi

247 lecules have been reported, highlighting the diverse roles that proteinaceous solvents play in dictat

248 t study provided data from a demographically diverse sample of 3523 New Zealand men who completed int

249 pact of surgeon recommendations, in a large, diverse sample of patients who underwent recent treatmen

250 gnostically interrogate nucleic acids within diverse sample types, but in the clinical setting are li

251 Geographically diverse samples from strawberry exhibiting symptoms of S

252 y, capable of interrogating high quality and diverse scaffold libraries with verifiable folding and s

253 Quick Guide, Votier and Sherley explain how diverse seabirds play important roles in ecosystem funct

254 stable and replicable ensemble responses to diverse sensory stimuli under various external condition

255 ial-geographical analysis indicated that the diverse sequences identified here did not expand globall

256 r haplotype assembly applicable to data from diverse sequencing technologies.

257 view studies that tackle this problem from a diverse set of approaches, from anatomy to electrophysio

258 l environments as stimuli, the other using a diverse set of complex, natural scenes.

259 ructure reflect complex interactions among a diverse set of processes that may vary temporally, limit

260 RBM10 recognizes a diverse set of RNA motifs in introns and exons and regul

261 s an essential second messenger required for diverse signaling processes in immune cells.

262 ent of more than 50 resequenced genomes from diverse sorghum genotypes to the reference genome identi

263 e increasing support that FDOM can have many diverse sources not consistently captured by common clas

264 arger group sizes in general but also to the diverse species composition in the groups.

265 ty, potentially complex, and hemodynamically diverse state of end-organ hypoperfusion that is frequen

266 K2P) channel ion conductance is regulated by diverse stimuli that directly or indirectly gate the cha

267 conditions, different cells often experience diverse stimulus time courses, which is a situation like

268 Therefore, the low level of adaptation in diverse streams cannot be explained by an increased reco

269 In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding prot

270 The diverse structure and regulated deformation of lipid bil

271 functions and cellular processes, and showed diverse subcellular localizations.

272 te an array of electronically and sterically diverse substituents and generate high yield and stereos

273 Two diverse superstructures of nanoscopic CdSe were prepared

274 tablished the existence of these patterns in diverse systems, rigorous testing, intensive time-series

275 orescence techniques are commonly applied to diverse systems, these results provide increasing suppor

276 ing cells that are functionally analogous to diverse T cell subsets.

277 contribute precise object motion signals to diverse targets without distorting target-specific contr

278 spond to climate variability, we analyzed 73 diverse taxa off the southeast US coast in 26 years of s

279 Soil communities are diverse taxonomically and functionally.

280 How the diverse TCRs interact with a multitude of MHC molecules

281 derlying the development and organization of diverse thalamic nuclei remain largely unknown.

282 le to simple peptide-based catalysts is more diverse than precedent might suggest.

283 /D1 West population that is genetically more diverse than the entire A1/D1 East cluster caused the su

284 e the priming effects are more confusing and diverse than their theory would suggest.

285 ntestinal viromes of case subjects were less diverse than those of controls.

286 Researchers from diverse theoretical backgrounds have studied workplace i

287 n clusters are structurally and functionally diverse, they are enriched in functions associated with

288 ltiple RAS-mutant human cancer cell lines of diverse tissue origin by blockade of nuclear FOXO4 degra

289 dsx knockdown, high-throughput sequencing of diverse tissues and a genome-wide analysis of Dsx-bindin

290 in distinct niches, from soil and plants to diverse tissues in human hosts.

291 PP2B-anchoring determinant sustaining these diverse topologies.

292 factor FOXO has been shown to interact with diverse transcription co-factors and integrate signals f

293 ative computational methods to analyze these diverse types of data provides new opportunities to impa

294 ctivation of Treg cells in the prevention of diverse types of inflammatory responses.

295 generating cells in the correct numbers and diverse types, and thus dictate proper brain development

296 duces intestinal colonization of genetically diverse UPEC isolates, while simultaneously treating UTI

297 They have been observed in diverse vertebrate groups, yet their roles in vision rem

298 he lack of evolutionary conservation amongst diverse viruses, it is not feasible to build a viral tre

299 genomes of 147 cotton accessions, including diverse wild relatives, landraces, and modern cultivars,

300 l T cells, the CDR3 sequences were extremely diverse, without any clonotype representing more than 2%