ライフサイエンスコーパス: diversification

1 sses of macrolide antibiotics via late-stage diversification.

2 h can cause new genome structure and species diversification.

3 ork for mechanistic studies of architectural diversification.

4 nctional small molecules amenable to further diversification.

5 its spatiotemporal dynamics and evolutionary diversification.

6 acial maximum, which are possible centres of diversification.

7 that this variability drives TCR repertoire diversification.

8 nt is proposed to have primed branching form diversification.

9 ues showed evidence of both conservation and diversification.

10 highly versatile and rapidly undergo further diversification.

11 data for modelling environmental drivers of diversification.

12 titute a general principle of neuron subtype diversification.

13 role in determining broad-scale patterns of diversification.

14 escribe their potential for population-level diversification.

15 y individual strains, followed by subsequent diversification.

16 et is associated with increased net rates of diversification.

17 s, consistent with early steps in functional diversification.

18 very little is known about their origin and diversification.

19 and may have contributed to constrain their diversification.

20 if transitions and the facilitation of their diversification.

21 ant intraspecific variation and evolutionary diversification.

22 iphery of the heteroaryl ring for late-stage diversification.

23 play important roles in adaptive phenotypic diversification.

24 y, ecological interactions, and evolutionary diversification.

25 the developmental and genomic mechanisms of diversification.

26 volutionized our understanding of angiosperm diversification.

27 and somatic hypermutation (SHM) in antibody diversification.

28 an amino acid site implicated in structural diversification.

29 might have affected Diodora, preventing its diversification.

30 a result of gene duplication and subsequent diversification.

31 mitochondrial barcodes and their ecological diversification.

32 use of chance generation during preimmune Ig diversification.

33 e evolution on broad-scale patterns of trait diversification.

34 infectious diseases, and is a key process in diversification.

35 s introduced new dimensions of feather shape diversification.

36 vely rapidly and may cause strong functional diversification.

37 correlate highly with their population-level diversification.

38 tion we identify two stages of architectural diversification.

39 g subtle biogeographical trends in Espeletia diversification.

40 evolution, with evidence of lineage-specific diversification.

41 ture, maintenance of cooperation, and strain diversification.

42 t could be used as branch points for further diversification.

43 vel ecological niches and subsequent lineage diversification.

44 ective regimes, thus promoting morphological diversification.

45 ion (WGD) is thought to promote evolutionary diversification.

46 lection that drove soybean domestication and diversification.

47 ems, and have probably experienced explosive diversifications.

48 thought to have played a major role in bird diversification [4-8], whereas functional significance o

49 ggests that mountain uplift promotes species diversification across all elevational zones.

50 The paramo ecosystem has the highest rate of diversification across plant lineages on earth, of which

51 dual fishers and how year-to-year changes in diversification affect revenue and revenue variability.

52 The various approaches for diversification allowed one tetrasaccharide to be conver

53 tic explanations for geographic variation in diversification among clades.

54 l of conspicuous morphological and taxonomic diversification among ray-fins centred on the Devonian-C

55 es different pathways, suggesting ecological diversification among syntrophs.

56 dicate that certain forms of cropping system diversification and alternative weed management strategi

57 ork has addressed the apparent lag of animal diversification and atmospheric oxygenation during this

58 tionary models suggest that herbivores drive diversification and community composition in plants.

59 ccur after WGDs, it is difficult to consider diversification and duplication to be tightly correlated

60 In this review, we discuss the diversification and ecological roles of the fungi over t

61 recombination are critical in shaping genome diversification and evolution.

62 s for geography and biome/habitat, estimated diversification and extinction rates, and evaluated biom

63 influenza A viruses (IAVs) facilitates viral diversification and has a significant epidemiological im

64 ed important roles in soybean domestication, diversification and improvement.

65 To understand the diversification and key evolutionary transitions of Hyme

66 utate immunoglobulins, and contribute to the diversification and lethality of cancers.

67 rly-arriving lineages occupy niche space via diversification and preclude dominance of later arrivals

68 ine nitrate could have allowed for the rapid diversification and proliferation of nitrate-using cyano

69 as intercropping, crop rotations, farm-level diversification and reduced agrochemical use.

70 eatures uniquely contribute to enhancing GrC diversification and redundancy.

71 ng communities over 34 years to test whether diversification and turnover in the composition of fishi

72 We tested whether diversification and variation in fishing revenues change

73 l subtle biogeographical trends in Espeletia diversification, and metabolomic evidence for allopatric

74 glands, evolutionary mechanisms for spidroin diversification, and non-spidroin genes with expression

75 s the best model describing follicular gland diversification, and revealed high rates of disparity.

76 timing and geography of a major Neotropical diversification, and suggests that mountain uplift promo

77 nt and understudied role in the maintenance, diversification, and transmission of IAVs in the wild-bi

78 nt and understudied role in the maintenance, diversification, and transmission of IAVs in the wild-bi

79 aminobutyric acid (GABA), various late-stage diversifications, and by mimicking enzymatic transformat

80 Whether species demography and diversification are driven primarily by extrinsic enviro

81 Organic farming and plant diversification are farm management schemes that may mit

82 The detailed patterns of neuronal diversification are lineage-specific and can differ dras

83 d reveal retrotransposition-mediated genomic diversification as a fundamental property of pluripotent

84 nd catch share programs could further reduce diversification as a result of consolidation.

85 origin, but because of high rates of lineage diversification associated with high rates of evolution

86 r results demonstrate how in situ ecological diversification at the micro-evolutionary level might fu

87 Both intra- and interpatient diversification at the plasmid and transposon level was

88 of the broader implications of intraspecific diversification because comparative analyses have focuse

89 -related antibody repertoire development and diversification before and during acute malaria in infan

90 ible, however, that latitudinal variation in diversification begins when divergence occurs within spe

91 Our studies thus suggest functional diversification between mCOMT and mTOMT, where mTOMT is

92 tion of NHC compounds, undergoing continuous diversification, broadens their range of applications an

93 iation is an important stage of evolutionary diversification, but its significance as a rate-limiting

94 e angiosperm phylogeny may also be linked to diversification by increasing reproductive isolation and

95 egions have likely contributed to Pteronymia diversification by providing compartmentalized habitats

96 Signatures of HIV gene diversification can allow precise cross-sectional survei

97 iversifies its sequence and that the rate of diversification can be controlled in cultured cells.

98 cial system, that is, market integration and diversification, can actually drive it towards instabili

99 secondary metabolites according to the main diversification centers of Espeletia are also identified

100 hat tropical ecosystems have higher rates of diversification, clade origination, and clade dispersal.

101 Callitris diversification coincides with the onset of aridity in A

102 s a powerful approach toward natural product diversification, combining the best of both worlds: expe

103 eased rate of vertebral column and body form diversification compared to lineages with a complex, aqu

104 eficial mutations during lysis from sequence diversification during lysogeny, allowing rapid adaptati

105 for the anatomical evolution and ecological diversification during the earliest mammalian history.

106 simultaneously estimate correlations between diversification dynamics and multiple environmental traj

107 by inferring the biogeographical history and diversification dynamics of the two largest Neotropical

108 es, consistent with a history of more stable diversification dynamics through time in the Tropics.

109 s paves an expressway to extensive subclonal diversification, elevated intratumoral heterogeneity, an

110 the Late Cretaceous with evidence for rapid diversification events during several geological periods

111 te Cambrian, a time interval between the two diversification events of the Early Palaeozoic.

112 all, both organic farming and in-field plant diversification exerted the strongest effects on pollina

113 Specifically, it is likely that animal diversification expanded not only temporally but also sp

114 We found that diversification for both groups was nearly always reduce

115 udies in Gerbera hybrida indicate functional diversification for SEPALLATA (SEP)-like MADS box genes

116 lower meristem maintenance, while functional diversification for three SEP1/2/4 clade genes in regula

117 ion of the association between seed mass and diversification has not been assessed across the angiosp

118 potato use, leading to its domestication and diversification, has been well-documented in, and confin

119 echanisms regulating VSG gene expression and diversification have been examined extensively, the dyna

120 reconstructions using RADseq loci recovered diversification histories consistent with a previous stu

121 into deep phylogenetic relationships and the diversification history of Rosaceae.

122 or through a process of gene duplication and diversification; however molecular evidence has so far r

123 gradients to identify mechanisms underlying diversification; (ii) performing spatially explicit land

124 phytes, but the trajectory of branching form diversification in bryophytes is unclear.

125 ed phylogeny demonstrates sympatric parallel diversification in climatic niche, leaf habit, and diver

126 ghlight the potential of antibody repertoire diversification in infants and toddlers.Somatic hypermut

127 (K/Pg) boundary, strongly supporting bounded diversification in Mesozoic tetrapods.

128 developmental change priming branching form diversification in mosses and provide a framework for me

129 t implications for understanding patterns of diversification in other lineages, including insects and

130 tion for the reported high rates of sequence diversification in retrotransposons.

131 e of their weak structural signals and rapid diversification in sequences.

132 of new inner ear organs and their functional diversification in the course of evolution.

133 Our results show how rapid diversification in the immune repertoire immediately aft

134 Sympatric parallel diversification in the oaks has shaped the diversity of

135 gence, and subcellular markers of functional diversification in the Rab GTPase gene family in three P

136 terestingly, we also discovered preferential diversification in the structure and expression of root

137 number of clones, ipilimumab induced greater diversification in the T-cell repertoire in IRAE patient

138 udy hybridization, introgression and lineage diversification in the widely distributed canyon live oa

139 uted to the genome downsizing and phenotypic diversification in this group, we performed comparative

140 zed lowlands and adjacent montane areas, but diversification in those areas remained scarce.

141 eographic data capture this initial stage of diversification in which populations become geographical

142 ocene, followed by subsequent Miocene tribal diversifications in central/southwestern Asia.

143 for differential functional specificity and diversification, including genes for the production of a

144 itudinal distribution that is underpinned by diversification into temperature ecotypes.

145 onary history, we find that targeted protein diversification is a pronounced trait of CPR and DPANN p

146 esults indicate the early history of crinoid diversification is characterized by early burst dynamics

147 Species diversification is correlated with Andean orogeny, and m

148 These results suggest phenotypic diversification is far more complex than models commonly

149 Retroelement-guided diversification is further shown to be active in current

150 a specialist herbivore and infer that their diversification is likely shaped by the functional inter

151 This functional diversification is reflected by differences in gene expr

152 Secondary diversification is thought to only ripen the antigen-bin

153 Thus, the net effect on diversification is uncertain.

154 Explosive diversification is widespread in eukaryotes, making it d

155 volutionary innovation that enabled metazoan diversification, leading to the formation of distinct ge

156 ever, in the course of evolution, functional diversification led to the acquisition of novel, plant-s

157 r each of these fisheries, we tested whether diversification levels, trends, and variation in fishing

158 ortant biological processes such as antibody diversification/maturation, restriction of viral infecti

159 e regulatory principle for neuronal subclass diversification may be conserved from nematodes to mice.

160 This diversification mechanism may provide CPR and DPANN orga

161 Two immunoglobulin (Ig) diversification mechanisms collaborate to provide protec

162 plexity is enabled by the variety of protein diversification mechanisms that exist at every step of t

163 ed viral lineages, which suggest that strain diversification occurred during host dispersal and assoc

164 The debate concerns whether diversification occurs primarily through geographic part

165 Secondary diversification occurs when Ig V regions undergo somatic

166 Resolving the early diversification of animal lineages has proven difficult,

167 DSBs to S sequences is critical for allowing diversification of antibody functions, while minimizing

168 nt auxin transport routes contributed to the diversification of branching forms in distinct land plan

169 s to eukaryotes and the subsequent explosive diversification of cellular and organismal complexity.

170 tor (GDNF) in the development and subsequent diversification of chemosensory neurons within the genic

171 Our results reveal a compelling functional diversification of cleavage factors in archaea, and prov

172 mate, and the leading role of aridity in the diversification of conifers.

173 stigating the developmental and evolutionary diversification of different organs and cell types.

174 e, while maintaining the capacity for facile diversification of displayed functionality.

175 geny, biogeographic history, and patterns of diversification of Elsholtzieae.

176 Middle Miocene onwards in promoting species diversification of Elsholtzieae.

177 c analyses, we provide evidence of metabolic diversification of enteric microbiota involved in the de

178 end of morphologies and contributions to the diversification of eudicots.

179 damental in the evolutionary maintenance and diversification of family living in these lizards.

180 and molecular processes that facilitate the diversification of flower structure.

181 opose a new plausible scenario for the early diversification of flowers, leading to new testable hypo

182 NA function, emphasizing how they facilitate diversification of gene programming during development.

183 ts during the Late Cretaceous, and the rapid diversification of genera from the early Oligocene onwar

184 Most research investigating evolutionary diversification of glands responsible for the production

185 on, mutant spectrum dynamics, and phenotypic diversification of hepatitis C virus (HCV) in the course

186 orted strains and is evidence that the local diversification of HIV in the DRC continues to outpace t

187 Speciation appears to parallel the diversification of hosts, including the rapid emergence

188 A major mechanism underlying the genetic diversification of influenza A virus is reassortment of

189 ected tropical diseases but knowledge on the diversification of its vectors, Triatominae (Hemiptera:

190 We show that the functional diversification of key gene families such as DCL and AGO

191 ant with the terrestrialization of Earth and diversification of land fungi and plants.

192 cies that originated successively during the diversification of land plants, predominantly via gene d

193 ploidization had a significant impact on the diversification of land plants.

194 s, which nevertheless could support temporal diversification of like combinations, suitable for learn

195 sterol biosynthesis existed well before the diversification of living eukaryotes, substantially pred

196 historic role of wild Solanum species in the diversification of long-day-adapted tetraploid potatoes,

197 We show that evolutionary diversification of major Marinimicrobia clades appears t

198 Complete mitochondrial genomes documented a diversification of maternal lineages over time.

199 , is associated with genome streamlining and diversification of membrane proteins.

200 age provides insight into the complexity and diversification of modern human culture during a key per

201 e duplications have driven the expansion and diversification of most PP2A gene families, members of f

202 Diversification of motor neurons into different classes,

203 tion of small molecules as catalysts for the diversification of natural product scaffolds is reviewed

204 y was successfully applied to the late-stage diversification of natural products and a marketed drug

205 stand the impact of the Andean uplift on the diversification of Neotropical lowland plant lineages.

206 nciple of nervous system organization is the diversification of neuron classes into subclasses that s

207 ting that modest changes in TraA can lead to diversification of new recognition groups in nature.

208 housand y ago and preceded the morphological diversification of North American bison, and the second

209 New World and has impacted considerably the diversification of numerous Neotropical lineages.

210 lymerase, suggesting a plausible pathway for diversification of NusG paralogs.

211 irst global-scale analysis investigating the diversification of one of the main forms of communicatio

212 have increased our knowledge of the initial diversification of osteichthyans while also highlighting

213 ht into the steps that led to the functional diversification of paralogues, we tracked duplicate rete

214 The diversification of phenotypic traits suggests that diseq

215 Understanding the diversification of polyploid crops in the circum-Mediter

216 To gain insight into the diversification of PP2A subunits, we used phylogenetic a

217 ong purifying selection, indicating that the diversification of prochlorosins is not constrained by c

218 is function and elucidate their role for the diversification of protein-protein interactions during e

219 , a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprin

220 Shifts in pollination may drive adaptive diversification of reproductive systems within plant lin

221 tic pollination is clearly implicated in the diversification of reproductive systems within Schiedea.

222 Diversification of SERCA regulators was much less extens

223 duplication event resulting from the ongoing diversification of sHsps in the Volvocales.

224 The early diversification of Solanaceae is thought to have occurre

225 nges in multiple pathway enzymes can lead to diversification of specialized metabolites in plants.

226 pstream primary metabolic regulation for the diversification of specialized plant metabolism.

227 ral vertebrate features, whereas the somatic diversification of structurally distinct antigen recepto

228 ety of diagnostic applications, with further diversification of synthesis match bio-applications whil

229 rmaceutical drug discovery is illustrated by diversification of Telmisartan (an antagonist for the an

230 ortant trait associated with the spectacular diversification of terrestrial insects.

231 al microbiome, which could further drive the diversification of the bacterial community.

232 s from Vegard's law are observed, due to the diversification of the bulk properties of Si and Ge, in

233 e, concomitant with weaning and accompanying diversification of the intestinal microbiota.

234 parental care may have played a role in the diversification of the lineage during this period.

235 ted insight into how sequence and structural diversification of the motor domain gives rise to specia

236 the primordial code expansion driven by the diversification of the repertoire of protein amino acids

237 s, trajectories and phylogenetic patterns of diversification of their follicular glands for chemical

238 mmals across geographic space influences the diversification of their gut bacteria.

239 t any 'Precambrian prelude' to the explosive diversification of these phyla in the Cambrian, c. 540-5

240 traits variation linked with climate and the diversification of this clade using a time-calibrated ph

241 truct deep relationships and reveal temporal diversification of this family.

242 graphy and past climatic fluctuations on the diversification of this genus.

243 However, the macroevolutionary diversification of traits responsible for chemical signa

244 sheds light on the structural and functional diversification of TTLL enzymes, and constitutes an init

245 The deepest diversifications of African lineages were complex, invol

246 ied the effects of organic farming and plant diversification on abundance, local diversity (communiti

247 Diversification on these islands may follow neutral mode

248 ional movement cause these species to resist diversification or specialization?

249 mate the impact of different factors on fern diversification over the past 400 million years by analy

250 he evolution of xylem hydraulic function and diversification patterns in Australia's most successful

251 c study of biogeography, niche evolution and diversification patterns in Quercus was performed using

252 e to infer spatial, elevational and temporal diversification patterns.

253 ify "clues" to predict the observed historic diversification patterns.

254 at smaller-seeded plants had higher rates of diversification, possibly due to improved colonisation p

255 process obscures the transmission tree, the diversification process and infectivity dynamics also ad

256 ating in the population and their continuing diversification process limit the efficacy of AIDS vacci

257 elucidate the mechanistic basis of neuronal diversification processes in the context of C.elegans ve

258 Here we evaluate these contrasting diversification processes using two AF social wasp speci

259 sults suggest that organic farming and plant diversification promote diverse arthropod metacommunitie

260 r core eudicot lineages and temporal mode of diversifications, providing new insights into the evolut

261 Two diversification pulses can be recognized in the early hi

262 Two identified increases of diversification rate are located in the stems leading to

263 ect reproduction success, it could influence diversification rate as compared with lineages that have

264 ent a highly supported eudicot phylogeny and diversification rate shifts using 31 newly generated tra

265 of clades, usually by correlating changes in diversification rate with environmental or trait shifts.

266 may often occur along with shifts in either diversification rate, climatic occupancy, or rate of evo

267 ith shifts in climatic occupancy and lineage diversification rate.

268 We show that differences in diversification rates (speciation minus extinction) betw

269 ther gains of ESD are associated with higher diversification rates compared to lineages with alternat

270 Bayesian analyses showed increased diversification rates in Fissurella possibly promoted by

271 additional traits known to positively affect diversification rates in orchids.

272 was used for molecular dating and estimating diversification rates in the genus.

273 Lineages with ESD have consistently higher diversification rates than related lineages with other s

274 Accelerated net diversification rates within Theaceae were also detected

275 proxy for sexual selection) does not predict diversification rates, but instead explains the rate at

276 d size are both associated with variation in diversification rates.

277 ification in climatic niche, leaf habit, and diversification rates.

278 the potential association of WGDs and higher diversification rates.

279 family (B56/PPP2R5) was driven by functional diversification rather than by the maintenance of gene d

280 nthionine synthetase suggests that structure diversification, rather than structure refinement, is th

281 AF) biota, and consequently two processes of diversification (refugia and barriers) have been propose

282 illions of years, promoting lineage-specific diversification regimes under prevailing ecological pres

283 Isotopes and diversification results suggest that the evolution of th

284 Diversification shifts associated with Laccaria's disper

285 Thirteen putative WGDs and 27 diversification shifts could be mapped onto the phylogen

286 While we find that many diversification shifts occur after WGDs, it is difficult

287 naive repertoire and diminished intralineage diversification, signifying a reduced substrate for moun

288 ly known which environmental factors promote diversification (speciation minus extinction) in clades.

289 c transformation represents a major skeletal diversification step in the biosynthesis of secondary me

290 etween Africa and South America prior to its diversification, supported by finding ancestral recombin

291 rst of post-Paleozoic echinoid morphological diversification that began in the Early Jurassic.

292 presents an additional mechanism of antibody diversification that can be selected in the immune respo

293 a, and the other reflecting a large shift in diversification that resulted in the remainder of Laccar

294 n and reduction of the mouthparts and insect diversification through development of new habits by flu

295 those obtainable with simple null models of diversification under stochastic lineage birth and death

296 graphic and climatic variables should affect diversification using a large dataset of bird sister gen

297 transform its climate-related benefits: (i) diversification via woody polyculture and (ii) expanded

298 of ocean chemistry and Early Cambrian animal diversification was not a simple cause-and-effect relati

299 nting a survivor from the earliest stages of diversification within Homo.

300 nt and temperature changes, and accommodates diversification without requiring postsynthetic manipula