ライフサイエンスコーパス: diversify

1 continue to occur and the virus continues to diversify.

2 able information on this topic is scarce and diversified.

3 hat are subtler due to how the paralogs have diversified.

4 the central highlands where Mimosa spp. have diversified.

5 ion 2 was then carried out, and a library of diversified 2,3,6-tri(hetero)arylated imidazo[1,2-a]imid

6 t Papuan and Aboriginal Australian ancestors diversified 25-40 thousand years ago (kya), suggesting p

7 ories, with prasinophyte green phytoplankton diversifying 850-650 Mya.

8 Evolution often diversifies a peptide hormone family into multiple subfa

9 This method was used to diversify a heterologous beta-carotene biosynthetic path

10 Strain-release amination can diversify a range of substrates with a multitude of desi

11 ons, a new AlaRS architecture was created by diversifying a preexisting appended domain.

12 Haemosporida) of birds are believed to have diversified across the avian host phylogeny well after t

13 tosynthetic capacity (Amax), as these traits diversified across this lineage in tight coordination, w

14 ades in which species are more successful at diversifying across climatic gradients have greater pote

15 technologies, neuroscience might be ready to diversify again, if provided the appropriate support.

16 nd reactivation from latency are complex and diversified among virus families, species, and strains.

17 on accompanies sexual reproduction and helps diversify an organism's offspring, so that parasites can

18 As lineages diversify, an early and often rapid phase of species and

19 ated trait and niche evolution in a recently diversified and ecologically diverse plant clade.

20 Here we studied one of the most diversified and medically relevant RNA virus families, t

21 dy reveals how lasso peptides are chemically diversified and sets the foundation for rational enginee

22 part of a critical regulatory strategy that diversifies and modulates transcriptional regulation by

23 B cells diversify and affinity mature their antigen receptor rep

24 l a strategy employed in the wild to rapidly diversify and grant distinct, useful roles to cellular s

25 Cytosine modifications diversify and structure the genome thereby controlling p

26 ontrast, randomizing maternal effects (i.e., diversifying and conservative bet-hedging), are expected

27 cellular properties, plays a crucial role in diversifying and increasing the computational power of a

28 Class switch recombination (CSR) diversifies antibodies for productive immune responses w

29 recombination (CSR) alters the Ig isotype to diversify antibody effector functions.

30 s suggest that extant Hymenoptera started to diversify around 281 million years ago (mya).

31 ophage program initiated in pMacs is rapidly diversified as expression of transcriptional regulators

32 Archosauromorph reptiles flourished and diversified as they filled empty ecological niches, and

33 and single-cell analysis demonstrated highly diversified ASCs punctuated by clones expressing the var

34 The majority of the avifauna diversifies at a slow rate, without detectable ecologica

35 y broadens the understanding of how bacteria diversify at the genomic level over the course of a defi

36 The outcome is instead a diversified B cell response.

37 hree of these sites were located in the same diversified B-cell/Ab epitope regions as identified in t

38 -effective POC diagnostics, immunoassays and diversified bioanalytical applications.

39 d consistently, multiple coexisting lineages diversified both phenotypically and genotypically.

40 colleagues discovered that antibodies can be diversified by DNA sequences encoded outside of antibody

41 encoded in the germline but are extensively diversified by somatic recombination and hypermutations.

42 8 iGluR receptor subunits, many of which are diversified by splicing and RNA editing, localize to >20

43 gen-specific TCR repertoire is progressively diversified by staggered clonotypic expansion, according

44 We propose that IHCs diversify Ca(2+) channel properties among AZs and thereb

45 Caenorhabditis elegans embryos rapidly diversify cell fate using a modified Wnt/beta-catenin si

46 enzymes primarily responsible for chemically diversifying cellular microtubules.

47 This scenario is based on establishing a diversified chain of facilities for the distribution of

48 er remained a major cause of death providing diversified challenges in terms of treatment including n

49 tency of several types of hPSCs using a more diversified clade of mammals, the ungulates.

50 ace plasmon resonance (SPR), we present this diversified collection to collagen and quantify the kine

51 and North America, we show that disturbance diversifies communities when dispersal is limited, but h

52 This diversified compensatory profile was associated with lar

53 an efficient method for the construction of diversified complexants through multi-Suzuki-Miyaura cro

54 as systematically integrated with chemically diversified cores, peripheries, and generations.

55 embers of the avian crown group) explosively diversified, culminating in more than 10,000 species dis

56 T cell repertoire in neonatal-infected mice diversified during persistent infection in both the brai

57 Angiosperms evolved and diversified during the Cretaceous period.

58 t the least because they evolved and rapidly diversified during the late Cambrian, a time interval be

59 Bacterial populations diversify during infection into distinct subpopulations

60 ct cystic fibrosis (CF) patients genetically diversify during infection.

61 Since opsins diversified early during metazoan evolution in the marin

62 ms, whose life cycles are characterized by a diversified ecology and epidemiology.

63 Storage had a diversified effect on GLS breakdown products (indole-3-a

64 ons include repurposing existing proteins to diversify endocytosis and trafficking, as well as prefer

65 rgetic functionalities, thereby resulting in diversified energetic compounds.

66 ete actions for the U.S. EPA to increase and diversify engagement with the scientific research commun

67 opaque, to undergo filamentation to adapt to diversified environments.

68 oocyte has a unique, dynamic and remarkably diversified epigenome characterized by the presence of b

69 We predicted that these diversified epitope regions would be the targets of muta

70 , representing an ancient plant lineage with diversified evergreen leaves.

71 y theoretical assumption made to explain the diversified evolution of isogamy and anisogamy in marine

72 usceptible host genotypes indicated possible diversifying evolution of PVY in the less-susceptible ho

73 uisition of new functions and can augment or diversify existing functions.

74 ound that circRNA and its parental gene have diversified expression patterns in gliomas and control b

75 g the expression of multiple genes that show diversified expression profiles.

76 a originated in the Northern Andes, where it diversified extensively.

77 ge-bodied, slow-breeding survivors failed to diversify, facing extinction despite earlier evolutionar

78 Here, we report the discovery of a diversified family of fish viruses, designated nackednav

79 sed on how pigment intensity and composition diversify, few, if any, have explored how a pattern elem

80 uate two axes by which fishers in Alaska can diversify fishing activities.

81 distributive mechanism responsible for both diversifying flux delivery to the shoreline and dampenin

82 reasingly generalized access to abundant and diversified food sources.

83 e of microscopic animals, have persisted and diversified for more than 60 Myr in an ameiotic fashion.

84 d to retain conserved hairpin structures but diversified for unique structures and functions in speci

85 These two diversifying forces promote genetic variation at differe

86 The cluster diversified from a common ancestor in the mid-twentieth

87 ata indicate that extant Pocillopora species diversified from a common ancestral lineage within the l

88 During the mid-Cretaceous, angiosperms diversified from several nondiverse lineages to their cu

89 Rainforest clades have diversified from the Late Oligocene or Early Miocene onw

90 x eukaryotic ubiquitylation system arose and diversified from these prokaryotic antecedents.

91 eisseriaceae have the fascinating ability to diversify functional sequences and yet retain the haemog

92 increasingly homogeneous phenotypes, and of diversified functionalities that combine to confer a CD8

93 hus, heterodimerization provides a means for diversifying functionality through an expansion of the c

94 riptional activity, and thus underscores the diversified functions of this regulatory complex.

95 new genes that can acquire similar but often diversified functions.

96 The findings suggest that community and diversified funding structures exhibit 40-100% higher so

97 trends arising from corporate, community and diversified funding structures.

98 ubunits, and variety in subunit combinations diversifies GABAAR functions to tune brain activity.

99 components and gene regulatory networks that diversifies gene expression spatially across developing

100 mechanism by which cancer subpopulations can diversify gene expression states, which may allow for en

101 nucleotide changes to RNA, thus potentially diversifying gene expression.

102 s Review describes some of the tools used to diversify genes, as well as informative examples of scre

103 (=Ectognatha), comprise the largest and most diversified group of living organisms, accounting for ro

104 t.IMPORTANCE Enteroviruses comprise a highly diversified group of viruses.

105 dysbiosis with an oxidized, acid, and poorly diversified gut microbiota.

106 abling escape from constraints of predation, diversified habitat use, and subsequently speciation.

107 The ability of fishers to diversify has become increasingly constrained in the las

108 finds the best restriction enzyme to further diversify HRM or FLP signatures.

109 ny of a single B cell responding to Ag, with diversified Ig receptors.

110 IGCR1 also diversifies IgH repertoires by balancing proximal and di

111 The enzymes RAG1-RAG2 and AID, which diversify immunoglobulin-encoding genes, are strictly se

112 These findings suggest that UCYN-A diversified in a co-evolutionary process, wherein their

113 multicellular organisms and are extensively diversified in animals.

114 ar, mitochondrial, and gut bacterial genomes diversified in concert during hominid evolution.

115 rent genotypes play disparate roles and have diversified in concert with their hosts.

116 Levels of Cut expression are diversified in distinct sensory neurons by selective exp

117 wo related tetraploids are indicated to have diversified in eastern Central Asia at approximately 5.8

118 how tRNA, and possibly the genetic code, is diversified in nature.

119 ave been disputed, particularly whether they diversified in response to events in plant evolution.

120 entalization of lymphoid tissues in mammals, diversified in salmonids leading to the presence of six

121 on related proteins (DRPs), which are highly diversified in T. gelatinosa, whereas Late Embryogenesis

122 mokines and chemokine receptors have rapidly diversified in teleost fish but their immune functions r

123 Marchantia polymorpha diversified in the Late Miocene, giving a minimum age es

124 e context, we determined that FXYDs markedly diversified in the lineages leading to cartilaginous fis

125 lacanth and tetrapods, and have expanded and diversified in the mammalian lineage.

126 Viburnum probably diversified in tropical forests of Southeast Asia in the

127 ow that YopJ family T3Es are not only highly diversified in virulence function but also appear to pos

128 plant pathogens, and its members are highly diversified in virulence functions.

129 The major lineages rapidly diversified in warm and wet habits during the Late Creta

130 es its role in development with pressures to diversify in response to viral attack.

131 tically unique adaptive NK cell subsets that diversify in response to viral infection and have distin

132 ctive constraints on DCL4 and allowing it to diversify in response to viral suppressors.

133 ve transitioned between habitats repeatedly, diversifying in rivers, lakes and oceans over evolutiona

134 in sex workers needs to be strengthened and diversified, including its role in aiding access to, and

135 y buffering alley crops to weather extremes, diversifying income to hedge financial risk, increasing

136 ole in protostome-deuterostome ancestors and diversified independently into several neuron types in a

137 ESA) gene families of mosses and seed plants diversified independently, CESA knockout analysis in the

138 In the recently diversified indigobird radiation (Vidua spp.), following

139 The diversified interactions between snowfall and temperatur

140 UCYN-A is widely distributed, and has diversified into a number of sublineages that could be e

141 e monoclonal in origin, and the CRCs further diversified into different subclones with heterogeneous

142 ectious gastroenteritis worldwide, and it is diversified into eight genetic assemblages (A to H), whi

143 wo mature fetal dopaminergic neuron subtypes diversified into five adult classes during postnatal dev

144 Thus, spidroins have diversified into glues in addition to task-specific, hig

145 Smooth muscle precursors further diversified into lamina propria cells directly adjacent

146 A key C24 ancestor diversified into major classes of longer and shorter cha

147 parallel during the Cenozoic, when army ants diversified into modern genera [12] and rose to ecologic

148 Lemurs have diversified into species with diverse daily activity pat

149 to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka

150 xperiments, during which an ancestral strain diversified into two coexisting ecotypes.

151 RNA viruses rapidly diversify into quasispecies of related genotypes.

152 is to evolve extreme embolism resistance and diversify into xeric environments.

153 globe at the end of the nineteenth century, diversifying into distinct lineages associated with the

154 4) Puf3 also expanded and diversified its targets in filamentous fungi, gaining in

155 em acts as an expressed genetic barcode that diversifies its sequence and that the rate of diversific

156 endent of the cerebellar cortex, potentially diversifying its roles in motor control.SIGNIFICANCE STA

157 d the increasing permeability of natural and diversified landscape.

158 from multi-copy clades containing especially diversified loci.

159 cene fossils shows that Solanaceae were well diversified long before final Gondwanan breakup.

160 ess frequent adaptation in genomes of slowly diversifying lupins and all other plant genera analysed.

161 protein-modifying enzymes that functionally diversify mammalian ribosomes.

162 timulates an already primed immune system to diversify memory B cells to recognize closely related, b

163 rait that may help clarify why some lineages diversify more than others because it confers adaptation

164 nt and pest management programs that utilize diversify mortality factors must be implemented to ensur

165 Alternative splicing diversifies mRNA transcripts in human cells.

166 uestion is whether temporal information that diversifies neuronal progeny within a single lineage als

167 -evolving MHC class I polymorphism serves to diversify NK cell and CD8 T cell responses in individual

168 ntheses of functionally and stereochemically diversified, novel spiropyrazolone fused 2-iminothiophen

169 The group is comparably young, starting to diversify only about 100 million years ago (mya), with a

170 and endosymbiotic gene transfer events have diversified oomycete metabolism, resulting in biochemica

171 rase domains of other family members produce diversified OPS structures.

172 mutations, mutations displaying evidence of diversifying or directional selection, or mutations with

173 forms of activation likely enhances but not diversifies outcomes of RET signaling.

174 Because pathogenic mechanisms can diversify over time or even differ based on the injury t

175 Because the functionally diversifying paralogues are still closely related to and

176 m are: dedicate a coordinator, offer credit, diversify participation, create a tiered structure, and

177 Identification of such diversified pathways, or modules, is needed to expand ou

178 a reliable proxy for rates after an initial diversifying phase.

179 nted a CRISPR/Cas9-based method to deplete a diversified population of a wild-type allele, allowing u

180 o evolve virus-like properties by generating diversified populations using Escherichia coli as an exp

181 cance of the overlap between heterogeneously diversified portfolios, which we use to build a validate

182 ners with different transcription factors to diversify postmitotic olfactory cell types.

183 that all local communities exhibit a highly diversified potential for the realization of key ecologi

184 (Idi1~NudB) along with a reductase (NemA) to diversify production to 3-methyl-2-buten-1-ol and 3-meth

185 dernourished people are smallholder farmers, diversifying production on these smallholder farms is wi

186 nd provide an overall access to structurally diversified products.

187 at permits quantitative assessment of highly diversified protein families.

188 importance of RNA recoding as a strategy for diversifying proteins, particularly those associated wit

189 of different geographical origin, suggesting diversified proteolytic activities.

190 his might explain how the GPCR-Galpha system diversified rapidly, while conserving the allosteric act

191 Predator and prey populations diversify rapidly leading to higher prey diversity when

192 Diversifying regulatory sequences and using native micro

193 Crown teleost fishes diversified relatively recently, during the Late Cretace

194 Cs yielded T-cell progenitors with a broadly diversified repertoire.

195 species more dependent on the larger or more diversified resource pool that natural habitats offer.

196 iod, the organs that give rise to roots have diversified, resulting in the evolution of numerous nove

197 tific research community by a) expanding and diversifying scientific input into the development and a

198 ows examination of microbial motion within a diversified, secluded and yet microscopically tractable

199 A scan for diversifying selection across taxa identifies strong and

200 re elevational generalists being sundered by diversifying selection along the gradient?

201 Taken together, these results suggest that diversifying selection analysis can identify key immune

202 expression, suggesting a correlation between diversifying selection and allelic differentiation.

203 They illustrate how diversifying selection can allow cells to adapt the nucl

204 identified 16 amino acid sites experiencing diversifying selection during the evolution of prepandem

205 question concerning possible involvement of diversifying selection in the bindin intron evolution mo

206 likelihood approaches suggest the action of diversifying selection in the bindin intron.

207 We document evidence of diversifying selection in three of six PLVA genomes from

208 of all the GALV strains and demonstrate that diversifying selection is acting on them, particularly i

209 predicts that both stabilising selection and diversifying selection jointly contribute to the evoluti

210 On the other hand, a possible case of diversifying selection of the virus was observed in less

211 morphological divergence, suggesting strong diversifying selection on body proportions across the c.

212 othesis that RNA interference (RNAi) imposes diversifying selection on RNA virus genomes, we quantifi

213 n, recombination, latent reservoir dynamics, diversifying selection pressure driven by the immune res

214 ility among prochlorosins is the result of a diversifying selection process that favors large, rather

215 Genomic signatures of episodic diversifying selection were detected among the gammaretr

216 escribed here, which combines an analysis of diversifying selection with an integration of immune epi

217 ng genetic variation that accumulated due to diversifying selection within the native range.

218 led by clusters of R genes that evolve under diversifying selection, by dispersed, pathogen-specific

219 of class II were under positive or episodic diversifying selection, compared with only 10% at class

220 Structural mimicry and diversifying selection-hallmarks of host-pathogen intera

221 d sites exhibiting signal for directional or diversifying selection.

222 ilizing selection, directional selection, or diversifying selection.

223 ha variants have been the target of positive diversifying selection.

224 thesis pathways and will help develop a more diversified set of tea flavors that would eventually sat

225 , one can obtain colloidal nanocrystals with diversified shapes by adjusting various thermodynamic or

226 and show that RppH-dependent degradation has diversified significantly during the course of evolution

227 multiplex social networks in an era of ever-diversifying social interaction layers.

228 me resistant to inhibition as compounds were diversified stepwise.

229 The diversified structures provide the possibility to achiev

230 s species complex, and across the entire and diversified subphylum of Saccharomycotina.

231 cular glands, which therefore originated and diversified subsequently during their evolutionary histo

232 ong costimulatory signals for augmenting and diversifying T-cell responses.

233 the killing efficiency of NK cells with the diversified target recognition of TCRs.

234 pathogen recognition were expanded and more diversified than genes associated with intracellular sig

235 ent developments in conjugated polymers have diversified the backbones to become elaborate heterocylc

236 receptor usage spatiotemporally controls and diversifies the effects of guidance cues in the adult br

237 g the intergranular exchange coupling, which diversifies the magnetic patterning process and extends

238 onal mechanism mediated by ADAR enzymes that diversifies the transcriptome by altering selected nucle

239 minase (AID) initiates mutagenic pathways to diversify the antibody genes during immune responses.

240 tself and upon the determination cascades to diversify the castor window.

241 B cells clonotypically diversify the CD4(+) T-cell response also to vaccination

242 chanism by which activated amino acids could diversify the chemical functionality of fatty acid membr

243 ation reaction as a plug and play toolkit to diversify the complexity of naturally occurring ketones.

244 ecombination (CSR) increase the affinity and diversify the effector functions of antibodies during im

245 While alternative splicing is known to diversify the functional characteristics of some genes,

246 y factors may provide a general mechanism to diversify the functional repertoire of clathrin adaptor

247 thium resources to meet rising demand and to diversify the global lithium supply chain.

248 as part of a stochastic mechanism to further diversify the Ig repertoire.

249 easure in a parallel fashion is important to diversify the questions that can be addressed.

250 used to modulate the range of expression and diversify the response to morphogen gradients.

251 ights into how cannabinoid receptor subtypes diversify the roles of cannabinoids in the brain.

252 articles have been incorporated to widen and diversify the scope of the light-driven liquid crystalli

253 of the final two steps provided a handle to diversify the stereochemical outcomes at C6 as well as C

254 s produced intricate machinery to covalently diversify the structure of proteins after their synthesi

255 placement has the potential to significantly diversify the substrates that can be hyperpolarized by P

256 se the chance of evading turbulent layers by diversifying the direction of migration within the popul

257 hin parasite populations and a mechanism for diversifying the genome-encoded VSG repertoire.

258 on-occluded OF and IF states can account for diversifying the ion-release dynamics and apparent affin

259 The complexity inherent in diversifying the research workforce underscores the need

260 Thus, these genes likely play vital roles in diversifying the useable nucleic acid components availab

261 nstitutional level--the leading universities diversified their collaborations and increasingly became

262 Results also proved that TAG1 and TAGL1 have diversified their functions in fruit development: while

263 evolutionarily distinct fungal lineages have diversified their metabolic capacities as they have evol

264 Closely related RPP1 homologs have diversified their recognition spectra through LRR expans

265 Many fishers diversify their income by participating in multiple fish

266 hidophytes and dinoflagellates, can actively diversify their migratory strategy in response to hydrod

267 ises when uniform fields of progenitor cells diversify their molecular fate while adopting higher-ord

268 ically express stress response mechanisms to diversify their population and hedge against stress.

269 utilize extensive chemical modifications to diversify their structures and functions.

270 Our data demonstrate that by diversifying their responsivity to growth cues, distinct

271 hromes P450 (CYPs), which modify and further diversify these scaffolds, so paving the way for further

272 nucleophiles or hetero-dinucleophiles in the diversified thiazolylidene ring assembly.

273 acts to suppress alternative morphologies to diversify three distinct types of somatosensory neurons.

274 morphology of Drosophila sensory neurons is diversified through a series of suppressive transcriptio

275 Like other herpesviruses, EBV has diversified through both coevolution with its host and g

276 ions suggest that IR1-and, by extension, EBV-diversifies through both recombination and breakpoint re

277 s, do not show elevated turnover but instead diversify through protein-sequence changes.

278 Interstitial progenitor cells diversify through the acquisition of HES1, an indication

279 Using this, we demonstrate that dynamins diversify through the punctuated transformation of seque

280 d whether the range of novel fuel types that diversified throughout the Cretaceous also altered fire

281 Early birds diversified throughout the Jurassic and Cretaceous, beco

282 In addition, the program has diversified to address measles and rubella elimination,

283 nes, but also pathways can be multiplied and diversified to perform related functions in different pa

284 The TOC receptor systems have diversified to recognize distinct sets of preproteins, t

285 n activator and also shows that MAPKs can be diversified to recognize unique phosphorylation motifs.

286 ability to bind to host receptors while also diversifying to aid immune evasion.

287 nstrate that RDD is a conserved process that diversifies transcriptomes and proteomes and provide a m

288 ns represent cost-effective opportunities to diversify urban water supplies.

289 te the detailed mechanisms that regulate and diversify vertebral patterning.

290 inish the potential for small-island taxa to diversify via dispersal.

291 ammal species globally and discovered highly diversified viruses in bats, rodents, hedgehogs, and shr

292 re most suitable for intensifying as well as diversifying wheat-rice rotations, but less so for rice-

293 From this state, some features diversified whereas others remained conserved across the

294 t to which such a surface protein family can diversify while maintaining ligand-binding capacity and

295 iota structure and function had expanded and diversified with demonstrable body site specificity (P <

296 a way that, in plants, some components have diversified with respect to their animal counterparts, w

297 er, recently this investment has become less diversified, with a larger fraction of grant dollars in

298 In parallel, gut microbiota rapidly diversified, with durable engraftment of spores and no o

299 and function had substantially expanded and diversified, with the body site serving as the primary d

300 Despite negative selection, mycobacteria diversified within individuals to form sublineages that