ライフサイエンスコーパス: dividing cell

1 align the spindle along the long axis of the dividing cell.

2 I) in the interphasic cells neighbouring the dividing cell.

3 as an immortal, slow-cycling, asymmetrically dividing cell.

4 was evident, suggesting selective purging of dividing cells.

5 opment of gene-targeting applications in non-dividing cells.

6 s are resistant to chemotherapy that targets dividing cells.

7 termini that is recognized by a receptor on dividing cells.

8 vered based on their ability to kill rapidly dividing cells.

9 of motile cells, and the cleavage furrow of dividing cells.

10 h specific chemical structures accumulate in dividing cells.

11 ous accumulation of repeat expansions in non-dividing cells.

12 highly correlated with lipids accumulated in dividing cells.

13 ivation and subsequent F-actin remodeling in dividing cells.

14 parameters from large empirical datasets of dividing cells.

15 abscission even in apparently symmetrically dividing cells.

16 del organisms for studying aging in actively dividing cells.

17 tribution of the G protein RomR within these dividing cells.

18 stems from in vitro studies of continuously dividing cells.

19 d that ultimately affect Z-ring formation in dividing cells.

20 -the divisome--that assembles at mid-cell in dividing cells.

21 ressed genes when comparing to GFP(-) faster-dividing cells.

22 dGTP or GTP found in either dividing or non-dividing cells.

23 g intracellular redox homeostasis in rapidly dividing cells.

24 dscape to ensure the epigenomic integrity of dividing cells.

25 s in the SDN-POA displayed the morphology of dividing cells.

26 plus-end-tagging by PRC1 is also observed in dividing cells.

27 the leading edge of constriction furrows in dividing cells.

28 allow transcription in nondividing or slowly dividing cells.

29 the slow changes in impedance of growing and dividing cells.

30 tosis is probably the most iconic process of dividing cells.

31 es replication stress (RS) and DNA damage in dividing cells.

32 gulator of Notch signaling in asymmetrically dividing cells.

33 ecting cell fate decisions in asymmetrically dividing cells.

34 nt and reveal its essential role in actively dividing cells.

35 ls long-range chromosome movement into newly dividing cells.

36 bility, homeostasis and DNA synthesis in non-dividing cells.

37 iffusive path adopted by an inert protein in dividing cells.

38 ry cell fate determination in asymmetrically dividing cells.

39 emains essential for TAD organization in non-dividing cells.

40 of membranous filaments connecting pairs of dividing cells.

41 et poorly defined roles in proliferating and dividing cells.

42 ablishes order on the micron-length scale in dividing cells.

43 zed PcsB mainly to the septa and equators of dividing cells.

44 strate for this reaction to identify rapidly dividing cells.

45 s widely assumed that tumors arise only from dividing cells.

46 d is excluded from the apical cell cortex of dividing cells.

47 brain and localizes to the spindle poles of dividing cells.

48 ate poorly between cancer cells and normally dividing cells.

49 ith aberrant PPB formation in asymmetrically dividing cells.

50 hromosomes to mediate episome persistence in dividing cells.

51 FN stimulation, it was rapidly diminished in dividing cells.

52 romosomes are accurately partitioned between dividing cells.

53 BrdU; 200 mg/kg), to label one population of dividing cells.

54 erphase cells and to the cytokinetic ring in dividing cells.

55 active in regions with actively growing and dividing cells.

56 and duct cell markers as well as markers for dividing cells.

57 o productively replicate in distinct sets of dividing cells.

58 amily and is constitutively expressed in all dividing cells.

59 toxic than the GGT inhibitor acivicin toward dividing cells.

60 ient long-term infection of dividing and non-dividing cells.

61 abscission when chromatin is trapped between dividing cells.

62 mportant role in viral genome maintenance in dividing cells.

63 d an expression pattern confined to actively dividing cells.

64 l anticancer drugs, which compromise rapidly dividing cells.

65 ies of two closely related MAP65 proteins in dividing cells.

66 ing in both symmetrically and asymmetrically dividing cells.

67 a, and a large class with high expression in dividing cells.

68 tenation also formed the contractile ring in dividing cells.

69 protein aggregates in otherwise unperturbed dividing cells.

70 equently linked to cell cycle transitions in dividing cells.

71 -2'-deoxyuridine (EdU) to profile individual dividing cells.

72 in filaments that facilitates cytokinesis in dividing cells.

73 se 1 expression, which is higher in actively dividing cells.

74 macromolecular synthesis demands of rapidly dividing cells.

75 itate stable propagation of tau pathology in dividing cells.

76 those prevailing either in cycling or in non-dividing cells.

77 ected cells and by maintaining its genome in dividing cells.

78 DNA damage supports the genomic integrity of dividing cells.

79 elivering the viral genome to the nucleus of dividing cells.

80 inding to SAMHD1 expression and stability in dividing cells.

81 replacement histone genes in long-lived non-dividing cells.

82 ssing the effects of small molecule drugs in dividing cells.

83 bryos generate a cap in other asymmetrically dividing cells.

84 bolic and energetic demands of these rapidly dividing cells.

85 d stability of kinetochore-MT attachments in dividing cells.

86 duced mitochondrial length characteristic of dividing cells.

87 ric segregation of fate determinants between dividing cells.

88 ation of labels incorporated into the DNA of dividing cells.

89 le F-actin for contractile ring formation in dividing cells.

90 ts can be unified by a model in which slowly dividing cells accumulate replication-associated DNA bre

91 Thus, our findings demonstrate that, in dividing cells, aggresomes are detrimental over the long

92 ensitive BrdU antibody (BD) was specific for dividing cells; all BrdU-labeled cells stained for Ki67,

93 The retention of GFP labeling in slowly dividing cells allowed for localization of these cells t

94 Dividing cells almost always adopt a spherical shape.

95 racterize the progression of a population of dividing cells along a branching process.

96 n causes DNA double-strand breaks in rapidly dividing cells, although whether it also affects general

97 r actin networks, and the cleavage furrow of dividing cells--always together with myosin-II.

98 g of adhesive cell-cell contacts between the dividing cell and its neighbours has profound implicatio

99 o monitor the location of the spindle in the dividing cell and, in the event of positioning errors, r

100 mistry helped to distinguish the subtypes of dividing cells and delineate their locations in the vent

101 the MDM1 protein localizes to centrioles of dividing cells and differentiating multiciliated cells.

102 e repeats during DNA replication in actively dividing cells and during transcription initiation in no

103 have revolutionized our ability to identify dividing cells and follow their fate in various tissues,

104 ajor microtubule organizing center (MTOC) in dividing cells and in many postmitotic, differentiated c

105 nt parvovirus DNA replication that occurs in dividing cells and is independent of cell cycle arrest.

106 stinctions between cytokinetic structures in dividing cells and muscle sarcomeres.

107 omodeoxyuridine (BrdU) was injected to label dividing cells and positive cells were quantified in the

108 ll-to-cell transmission of tau aggregates in dividing cells and possibly neurons.

109 icate that the SAC-RNA CircPVT1, elevated in dividing cells and reduced in senescent cells, sequester

110 to the classic view, most mutations arise in dividing cells and result from uncorrected errors of S-p

111 adult dentate gyrus were derived from early-dividing cells and retained BrdU, suggesting that a subp

112 aphy to image the native structure of intact dividing cells and show that constriction in a variety o

113 opy in samples up to 20 mum thick, including dividing cells and the neuromast organ of a zebrafish em

114 erences in the mechanical properties of live dividing cells and their isolated lipids relative to non

115 ities necessary for [PSI(+) ] propagation in dividing cells and they get diluted out as cells multipl

116 er lentiviruses are capable of infecting non-dividing cells and, therefore, need to be imported into

117 vels of antiapoptotic Bcl-2 expression, some dividing cells, and clear alkaline phosphatase activity

118 and VPS4 were recruited to the midbodies of dividing cells, and depleting either IST1 or CHMP1 prote

119 ion of chromosomes during metaphase of 2,572 dividing cells, and developed a software package called

120 ctors produced high-titer stocks, transduced dividing cells, and did not integrate.

121 function, with fewer satellite cells, fewer dividing cells, and increased apoptotic cells in Mtm1del

122 phosphorylation is low in interphase versus dividing cells, and its levels rise with states of nucle

123 identify FoxM1 as a key regulator of ROS in dividing cells, and provide insights into the mechanism

124 rically dividing cells than in symmetrically dividing cells, and that DCD1/ADD1 may have other roles

125 R1) and histone deacetylase 2 in these early dividing cells; and (3) is required for neuronal maturat

126 Mitotically dividing cells appear to be less dependent on translatio

127 labeling and cell sorting, we show that the dividing cells are more susceptible to killing by tobram

128 To this end, researchers monitor changes in dividing cells as they traverse the cell cycle, with the

129 ergetics and biosynthetic demands of rapidly dividing cells as well as to counter a shift in cellular

130 of cells corralling a population of rapidly dividing cells at its center.

131 trically into a population of asynchronously dividing cells at the anterior end of the embryo.

132 d CeGrip-1 that are centrosome components in dividing cells become localized to the apical membrane,

133 termined that LSD1 (1) is expressed in early dividing cells before OR expression and neuronal maturat

134 These studies reveal how symmetrically dividing cells both exploit and conform to tissue organi

135 onfined RhoA-GTP at the equatorial cortex of dividing cells, both the target specificity of Mgc's GAP

136 ust alter not only proteins intrinsic to the dividing cell but also their interacting partners on nei

137 death via mitotic arrest applies to rapidly dividing cells but cannot explain MTA activity in slowly

138 erentially taken up by arrested and actively dividing cells, but PET measures only aggregate uptake b

139 merases are essential for DNA replication in dividing cells, but their genomic targets and function i

140 g bipolarization, it ultimately benefits the dividing cell by promoting robust kinetochore attachment

141 dividing cells to be distinguished from non-dividing cells by a greater than two-fold increase in ce

142 Cytokinesis physically separates dividing cells by forming a contractile actomyosin ring.

143 ivision and directly results in the death of dividing cells by reducing the levels of an essential re

144 tivation is co-ordinated to cell division in dividing cells by specific interactions that occur withi

145 Dividing cells called neoblasts contain pluripotent stem

146 ive tissue turnover because of the action of dividing cells called neoblasts.

147 nce of myosin activity on the two sides of a dividing cell can govern the size and fate of the daught

148 Even symmetrically dividing cells can then by chance produce daughters with

149 fore, SAMHD1 expression, particularly in non-dividing cells, can restrict retroviral infections such

150 ty leading to incorrect chromosome number in dividing cells-can arise from defects in centrosome dupl

151 In actively dividing cells, centrioles establish the bipolar mitotic

152 In dividing cells, chromosome duplication once per generati

153 During development, dividing cells control the position of the spindle to de

154 The majority of dividing cells corresponded to biciliated Ecc cells.

155 d it is not clear how a drug that only kills dividing cells could promote tumor regression.

156 In dividing cells, cytoplasmic dilution is the dominant rou

157 th in Arabidopsis thaliana by defining where dividing cells, derived from stem cells of the root meri

158 Dividing cells detach from the surrounding matrix and in

159 In dividing cells, DNA replication occurs in a precise orde

160 Here we identify long-lived proteins in dividing cells during aging using the budding yeast, Sac

161 ribes the orientation of the mitotic axes of dividing cells during development with respect to the lu

162 vivo tracking and cell fate analyses of all dividing cells during lateral line hair cell regeneratio

163 Dividing cells embedded in fibrous matrices remained anc

164 s localized to cell plates in all classes of dividing cells examined.

165 AID protein was functional because AID(+) dividing cells exhibited more double-stranded DNA breaks

166 rt long-term expression of transgenes in non-dividing cells, exhibiting a decreased risk of insertion

167 Growing and dividing cells expand their PG layer by using membrane-a

168 ce intensities in subpopulations of live and dividing cells exposed or not exposed to different dosag

169 Using time-lapse microscopy of growing and dividing cells expressing a gfp-minD fusion, we show tha

170 Embryos and tumors are both masses of dividing cells expressing foreign Ags, but they are not

171 h H3.3-YFP deposition stably remained in non-dividing cells for days after IFN stimulation, it was ra

172 driven by Adr protects the peptidoglycan of dividing cells from cleavage by the major autolysin LytA

173 As the number of slow-dividing cells grows, their cycling-rate increases, even

174 somatic cell nuclei appeared normal, whereas dividing cells had abnormal nuclear envelope and chromat

175 However, the dividing cells had high mRNA levels for genes regulated

176 of organelle partitioning in asymmetrically dividing cells has provided insights into the mechanisms

177 Previous studies in dividing cells have shown that mTORC1 blocks autophagy t

178 To maintain a constant cell size, dividing cells have to coordinate cell-cycle events with

179 In rapidly dividing cells, IL-12 programmed T(EM) through induction

180 tituent cell types, including progenitor and dividing cells, immature granule cells, astrocytes, olig

181 e duration of leaf elongation by maintaining dividing cells in a proliferative, undifferentiated stat

182 ation indicated an increase in the number of dividing cells in male diencephalon (p < 0.05, Kruskal-W

183 zed to the centrosome and mitotic spindle of dividing cells in multiple cell lines, including MDCK, m

184 is lost at a steady, quantifiable rate from dividing cells in the absence of antibiotic selection.

185 e also found that substantial numbers of the dividing cells in the adult dentate gyrus were derived f

186 afferentation did not immediately affect the dividing cells in the bulb but did affect the number of

187 micentins assemble at the cleavage furrow of dividing cells in the C. elegans germline and in preimpl

188 suggests that the vast majority of postnatal dividing cells in the central canal are Ecc cells and th

189 Clonal analysis of L3 Tr2 revealed that dividing cells in the dorsal trunk, dorsal branch and tr

190 Cilia are found on most non-dividing cells in the human body and, when faulty, cause

191 most of which was unbound) were found within dividing cells in the root tip cell proliferation zone.

192 ctions in microvascular density and actively dividing cells in the tumor sections after treatment in

193 LeuCAG3'tsRNA, induces apoptosis in rapidly dividing cells in vitro and in a patient-derived orthoto

194 robust DNA knock-in in both dividing and non-dividing cells in vitro and, more importantly, in vivo (

195 riod, is well suited to the study of rapidly dividing cells, in contrast to the longer term labeling

196 n to repress early meiosis-specific genes in dividing cells, in mitotic repression of meiosis-specifi

197 hich results in an increase in the number of dividing cells including transit-amplifying cells and ne

198 sequences to the chromosome ends in actively dividing cells, including 90% of all cancer cells.

199 In rapidly dividing cells, including the majority of human cancers,

200 ing in both asymmetrically and symmetrically dividing cells, independent of its function in spindle p

201 nce correlation spectroscopy measurements in dividing cells indicated that a slow-diffusing, possibly

202 lves efficient and accurate splitting of the dividing cell into two separate entities.

203 ing the levels of telomerase in continuously dividing cells is important for understanding how much t

204 The data indicate that YycG activity in non-dividing cells is suppressed by its interaction with Yyc

205 es of Xenopus laevis, as an example of a non-dividing cell, is exclusive to the nuclear pore complex

206 hich leads to the physical separation of two dividing cells, is normally restrained until after nucle

207 quired for Notch signaling in asymmetrically dividing cells, is sequestered from the plasma membrane

208 In dividing cells, its complex architecture not only influe

209 itotic behavior in ureteric bud tips whereby dividing cells leave the epithelium for the lumen, retai

210 the thymidine analog BrdU into the genes of dividing cells makes the fate of postmitotic neurons mor

211 been considered to be largely restricted to dividing cells, making it challenging to apply the techn

212 The mechanism of targeting stable dividing cells may have implications for the treatment o

213 omosomal episome, with stable maintenance in dividing cells mediated by the viral proteins Epstein-Ba

214 How dividing cells monitor the effective transmission of gen

215 repair of DNA lesions is a crucial task that dividing cells must actively perform to maintain genome

216 Continuously dividing cells must be protected from telomeric and nont

217 They surround a group of slowly dividing cells named the quiescent center (QC), and, tog

218 inal step of cytokinesis, termed abscission, dividing cells need to ensure that the cleavage plane is

219 In dividing cells, nuclear pore complexes (NPCs) disassembl

220 In dividing cells of the mammalian skin, planar cell polari

221 -dependent cell death pathway in the rapidly dividing cells of the mouse embryo.

222 depending on whether the cell affected is a dividing cell or a post-mitotic neuron, responses to the

223 Dividing cells or CD45-staining cells were not detected

224 long-lived proteins exist in asymmetrically dividing cells or whether they are involved in aging.

225 In dividing cells, Pbl promotes Rho1 activation at the cell

226 The presence of dividing cells peaks in the CC lining on postnatal day 8

227 Actively dividing cells perform robust and accurate DNA replicati

228 lows HVS-based vectors to stably transduce a dividing cell population and provide sustained transgene

229 asymmetrically in an otherwise symmetrically dividing cell population just upstream of cell fate dete

230 T cells (T(reg) cells) represent an actively dividing cell population with critical function in suppr

231 ble, and became progressively diluted in the dividing cell population.

232 s may reduce cancer risk by partitioning the dividing cell populations into lineages comprising infre

233 ystem but maintain replication competence in dividing cell populations, such as those found in brain

234 ynthesis enzyme uniquely enriched in rapidly dividing cell populations.

235 ke reflect changes in the number of actively dividing cells, provided other parameters remain the sam

236 r simulations predict that the location of a dividing cell, rather than the orientation of the divisi

237 Dividing cells rely on the "conditionally essential" ami

238 e in trans, Vangl2 proteins intrinsic to the dividing cell remain associated with the plasma membrane

239 nted mitosis may help maintain morphology as dividing cells replace those that have been lost.

240 How do plants determine the number of dividing cells required to optimise root growth and ensu

241 n of the overall sterol composition of young dividing cells reversibly impaired the PD localization o

242 In dividing cells, ribosomes accumulate on both sides of th

243 ii) the increased metabolic needs of rapidly dividing cells serve as an evolutionary pressure for the

244 ated MreCD(Spn) to the equators and septa of dividing cells, similarly to the PBPs and PG pentapeptid

245 V-1) contributes to viral replication in non-dividing cells, specifically those of the myeloid lineag

246 low dNTP concentrations, but not in rapidly dividing cells such as cancer cells, which contain high

247 prolonged absence of telomerase activity in dividing cells, telomeres eventually become critically s

248 HEK293 cells are the only dividing cells tested that fully support the replication

249 function is more critical in asymmetrically dividing cells than in symmetrically dividing cells, and

250 rgrowth by increasing the number of actively dividing cells that accumulate high levels of phosphoryl

251 st time a GEF controlling Rac1 activation in dividing cells that counteracts MgcRacGAP function in cy

252 repeated initiation of meristems, regions of dividing cells that give rise to new organs.

253 neration requires neoblasts, a population of dividing cells that has been studied for over a century.

254 erentiation, nonhuman origins, or the use of dividing cells that have neuropotential but lack neurona

255 In symmetrically dividing cells the nascent transcription rate increases

256 In a population of dividing cells, the competition between viral genomes pr

257 In many asymmetrically dividing cells, the microtubule-organizing centers (MTOC

258 vo and in vitro data reveals that in rapidly dividing cells there are vastly fewer structured mRNA re

259 ition is the short-range elimination of slow-dividing cells through apoptosis when confronted with a

260 idine (BrdU) was given systemically to label dividing cells throughout the experiment.

261 1 more potently in nondividing cells than in dividing cells, thus rendering HIV-1 infection dependent

262 Cak1 is constitutively active and expressed, dividing cells tightly regulate Cak1 protein levels to e

263 ee, focus-free information rich images allow dividing cells to be distinguished from non-dividing cel

264 on the ends of chromosomes, allowing rapidly dividing cells to proliferate while avoiding senescence

265 Genomes are transmitted faithfully from dividing cells to their offspring.

266 the desiccation sensitivity of exponentially dividing cells to understand the stresses imposed by des

267 roblem-positioning of the cleavage furrow in dividing cells-to explain how and why DE and AB models a

268 n protein complex holds sister chromatids in dividing cells together and is essential for chromosome

269 In actively dividing cells, translational repression was followed by

270 ortin(+) A cells were the second-most common dividing cell type in the V-SVZ and had a T(C) of 18 h a

271 at might be in place in other asymmetrically dividing cell types.

272 cancers to meet the folate demand of rapidly dividing cells under low folate conditions.

273 However, the aging process also occurs in dividing cells undergoing repeated asymmetric divisions.

274 B-GFP expressed at E9.5 to become diluted in dividing cells until the young adult stage, we determine

275 Mitotically dividing cells use a surveillance mechanism, the spindle

276 eplication defect of a virus lacking UL97 in dividing cells, validating this explanation.

277 n by stabilizing the mitotic spindle in fast-dividing cells via Misu and NuSAP.

278 plants instead synthesize and assemble a new dividing cell wall to separate newly formed daughter cel

279 The identity of dividing cells was determined by 3D ultrastructural reco

280 The number of dividing cells was higher in male rNPCs compared to fema

281 cal cell division, the proportion of apical (dividing) cells was quantified and telomere length, telo

282 Although expansions can accrue in non-dividing cells, we also show that cell cycle arrest is n

283 hich MLL perpetuates active transcription in dividing cells, we investigated its role during M phase

284 Importantly, the rates of expansion in non-dividing cells were at least as high as those of prolife

285 Dividing cells were found at the base of neuronal column

286 Dividing cells were primarily associated with affected i

287 roxide, an effect that was enhanced when the dividing cells were treated with salicylic acid.

288 udes access of the pDNA to the nuclei of non-dividing cells where the presence of an intact nuclear m

289 s is in contrast to previous observations in dividing cells, where P-TEFb can be regulated by its seq

290 for the de novo establishment of H3K27me3 in dividing cells, whereas PRC2-Ezh1 is required for its ma

291 ponsible for Acm2 targeting to the septum of dividing cells, whereas the AST domain and its O-glycosy

292 e studies of heterogeneity among growing and dividing cells, whether in microbes or in differentiatin

293 nt tools are inefficient, especially for non-dividing cells, which compose most adult tissues.

294 therapeutics nonselectively kill all rapidly dividing cells, which produces numerous side effects.

295 Whether dividing cells, which temporarily reduce their attachmen

296 resent in poorly differentiated and actively dividing cells, while Ezh1 associates with PRC2 in all c

297 endent fashion, allowing isolation of slowly dividing cells with retained nuclear GFP signal.

298 tatic cell numbers by matching the number of dividing cells with the number of dying cells.

299 intercellular Celsr1 complexes that connect dividing cells with their neighbors remain intact during

300 Treatment of dividing cells with these compounds induced DNA damage a