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1 antly a monomer and the activated state is a dodecamer.
2 binding does not require its assembly into a dodecamer.
3 osine on the structure of the Dickerson-Drew dodecamer.
4 out 20% of the trimer is incompetent to form dodecamer.
5 lU(DeltaI) hexamer binds one end of the HslV dodecamer.
6 base pairing remained intact throughout the dodecamer.
7 paired C and G bases in the CCATGCGCTGAC DNA dodecamer.
8 erminus of each subunit in the centre of the dodecamer.
9 sociated off center with a single layer of a dodecamer.
10 ystallographic 2-fold symmetry form the SpeG dodecamer.
11 al arrangement about a central cavity form a dodecamer.
12 uciform tetramers assemble into a triangular dodecamer.
13 crystal structure of a substrate-bound DegP dodecamer.
14 binding site on the interior surface of the dodecamer.
15 y synthesizing a homologous series up to the dodecamer.
16 Abeta42 alone produces oligomers as large as dodecamers.
17 group in rF:G pairs of the investigated RNA dodecamers.
18 are thought to do so only as fully assembled dodecamers.
19 do-tridecamer, and spermidine for the pseudo-dodecamers.
20 er oligopeptides to simulate the spectra for dodecamers.
21 for the assembly and secretion of functional dodecamers.
22 isulfide-cross-linked, trimeric subunits and dodecamers.
23 culture as trimeric subunits rather than as dodecamers.
24 l oligomers, including dimers, hexamers, and dodecamers.
25 nstead of an excess of HOCl, as observed for dodecamers.
26 re both 750-kilodalton (kDa) alpha(6)beta(6) dodecamers.
27 y could be the most stable species for Abeta dodecamers.
28 to three distinct oligomers: nonamer (9mer), dodecamer (12mer), and the previously characterized octa
29 ynamics trajectories of two solvated A-tract dodecamers: 1D89, d(CGCGA(6)CG), and 1D98, d(CGCA(6)GCG)
30 ics of opening of AT/TA basepairs in the DNA dodecamer 5'-d(GCTATAAAAGGG)-3'/5'-d(CCCTTTTATAGC)-3'.
32 Z3dU) and 7-deaza-dG into the Dickerson-Drew dodecamers 5'-d(C (1)G (2)C (3)G (4)A (5)A (6)T (7)T (8)
33 structure and dynamics of the Dickerson DNA dodecamer [5'd(CGCGAATTCGCG)2] in solution have been inv
34 els of insoluble amyloid-beta (Abeta), Abeta dodecamers (Abeta*56), prefibrillar soluble oligomers, a
36 minal arms are located on the outside of the dodecamer, accessible for interaction with client protei
37 structure into a 19-A cryo-EM map of a VacA dodecamer allows us to propose a model for how VacA mono
40 ntal observation, for (i) the Dickerson-Drew dodecamer and (ii) three oligomers containing A-tracts.
41 trates that the dimeric interface within the dodecamer and a Lys-Trp-Lys triad at the center of the r
42 In this study, we used two forms of SP-D, a dodecamer and a shorter fragment containing the trimeric
44 entify the enzyme(s) that cross-links the 7S dodecamer and characterize its expression in the kidney
47 ing the tetramer, conjugates of the octamer, dodecamer and hexadecamer elicited IgG LPS antibodies af
48 ose-deoxyribose mutations in a single-strand dodecamer and in trinucleotide models suggest that in th
49 multiple subunit contacts between the CaMKII dodecamer and the F-actin cytoskeleton that stabilize th
50 with natural SP-D (10 micro g/ml) containing dodecamers and higher-order forms exhibited aggregation
51 e the different lengths of DNA in the pseudo-dodecamers and pseudo-tridecamer, all three structures f
52 metry to investigate glutamate dehydrogenase dodecamers and serum amyloid P decamers as a function of
53 mers, trimers, and homomultimers as large as dodecamers and that CsmA directly interacts with the Fen
54 n that this family of proteins assemble into dodecamers and their quaternary structure is entirely cr
55 a DNA segment with 12 base pairs (Dickerson dodecamer) and a (8,8) SWNT in water, with counterions t
56 ling model that active Vps4 is a double-ring dodecamer, and argue that, like other type I AAA ATPases
57 emble in a tetrahedral arrangement to form a dodecamer, and five dodecamers pack together to form an
58 metal site is necessary for formation of the dodecamer, and metal binding at this site facilitates ol
60 atomic models for the T4 portal monomer and dodecamer, and we fit the dodecamer into the cryo-electr
62 he CD spectra of analogous peptoid hexamers, dodecamers, and pentadecamers, composed entirely of eith
63 erminal disulfides are required to stabilize dodecamers, and support our hypothesis that the oligomer
64 d that the two HslV(6) rings in the protease dodecamer are activated independently rather than cooper
72 hemoglobin chains that are assembled into 12 dodecamers arranged at the periphery of the complex arou
74 MR to follow the secondary structure of this dodecamer as the solution composition was changed stepwi
76 nt species, pea, wheat, and Arabidopsis, are dodecamers as determined by nano-electrospray mass spect
78 .X hydrogen bonds must be weakened to effect dodecamer assembly and that the molecular mechanism invo
80 R indicate that this photoinduced hexamer-to-dodecamer association occurs through intermolecular beta
83 th the sodium and the potassium forms of the dodecamer at high resolution indicate that the original
86 versatile enzyme is known to form functional dodecamers at its optimal pH and is thought to work in c
87 shown that AT can homooligomerize to form a dodecamer, AT(12), composed of a tetramer of trimers, AT
90 , does not significantly form the hexamer or dodecamer but instead produces a mixture of smaller olig
92 K not only inhibits the formation of Abeta42 dodecamers, but also removes preformed Abeta42 dodecamer
93 6M34A and Cx26V84L are stable as hexamers or dodecamers, but Cx26T135A and Cx26P87L oligomers are not
95 ifferent molecular forms of SP-D showed that dodecamers-but not trimeric subunits-mediate optimal agg
96 duct, G[8,5-Me]T, embedded in a solvated DNA dodecamer by means of quantum mechanics/molecular mechan
97 e we report fibril propagation of an Abeta42 dodecamer called large fatty acid-derived oligomers (LFA
98 ted complexes demonstrated that each HSP18.1 dodecamer can bind the equivalent of 12 MDH monomers, in
102 ost active compounds bound to an AT-rich DNA dodecamer (CGCGAATTCGCG)2 and using DSC were found to in
103 tion structure of the self-complementary DNA dodecamer (CGT_GACGT_TACG above GCAT_TGCAG_TGC] which co
105 otein D (SP-D) is preferentially secreted as dodecamers consisting of four collagenous trimers cross-
107 he octamers are tetramers of dimers; and the dodecamers contain two trimer subunits surrounded by thr
108 The solution structures of a duplex DNA dodecamer containing a cis-syn cyclobutane thymine dimer
109 herefore, the structure of a double-stranded dodecamer containing a tetrahydrofuran apurinic lesion a
110 on of the NMR measurements collected on four dodecamers containing a substantial set of dinucleotide
112 t for antiviral and anticancer drugs, pseudo-dodecamer crystals were soaked with one such antiviral a
113 d the three-dimensional structure of the DNA dodecamer d(CGC[iG]AATTTGCG) (denoted iG-DODE) by X-ray
115 rystal structure refinement of the synthetic dodecamer d(CGCGAASSCGCG), where S = 4'-thio-2'-deoxythy
116 son of its structure with that of the native dodecamer d(CGCGAATTCGCG) has revealed that the major di
118 f the complex between furamidine and the DNA dodecamer d(CGCGAATTCGCG)2 and compared it with the same
120 The approach is demonstrated for the DNA dodecamer d(CGCGAATTCGCG)2, where direct interactions ar
124 ons were carried out for the double-stranded dodecamer d(GGTATATAAAAC), in which a transition from A-
126 simulations were performed on the duplex DNA dodecamers d(CGCGAA TT CGCG): d(CGCGAATTCGCG) and d(GCAC
129 ution solution structure of the cross-linked dodecamer [d(GCATCCGGATGC)]2 (the cross-linked guanines
131 tential to the structure refinement of a DNA dodecamer, d(CGCGAATTCGCG)(2), for which NOE and dipolar
132 e 1.7 A X-ray crystal structure of the B-DNA dodecamer, [d(CGCGAATTCGCG)] (DDD)-bound non-covalently
133 The structure of the modified Dickerson-Drew dodecamer (DDD) in which guanine at position G(4) has be
134 th sequence CGCGAATTCGCG, the Dickerson-Drew dodecamer (DDD), established a unique geometry of the ce
135 ong-timescale dynamics of the Drew-Dickerson dodecamer (DDD: d(CGCGAATTGCGC)2) a prototypical B-DNA d
136 uble-stranded B-DNA dodecamer (the Dickerson Dodecamer, DDD, [d(CGCGAATTCGCG)]2) associated with a cy
137 uits a hexamer-forming peptide to form mixed dodecamers demonstrates that one species can dictate the
138 ds to predict the structure of two new B-DNA dodecamers, determined herein by means of 1H nuclear mag
139 with North-locked sugars (RNA-like) into the dodecamer did not greatly affect duplex formation or mel
142 simulations were performed on models of the dodecamer DNA double-stranded segment, [d(CGCGAATTCGCG)]
143 stal structure of the non-self-complementary dodecamer DNA duplex formed by d(CG[5BrC]ATAT-TTGCG) and
144 irs were attached to selected positions of a dodecamer DNA duplex with a known NMR structure, and eig
147 n structure of the nitrous acid cross-linked dodecamer duplex [d(GCATCCGGATGC)]2 (the cross-linked gu
148 t the two independent iG.T base pairs in the dodecamer duplex adopt different (one in Watson-Crick an
150 he 5'-CpG-3' sequence was monitored within a dodecamer duplex by NMR spectroscopy, in situ, using a s
152 ined four crystal structures of a B-form DNA dodecamer duplex containing ClU:A or ClU:G base pairs.
156 hotoproducts formed in a TATA box-containing dodecamer duplex sequence in the presence or absence of
157 tosecond resolution, at the surface of a DNA dodecamer duplex whose native structure remains unpertur
158 e at atomic resolution determined for an RNA dodecamer duplex with rF opposite G manifests only minor
159 solution structure of a second cross-linked dodecamer duplex, [d(CGCTACGTAGCG)]2, which shows that t
160 onformations of these ANA analogues in a DNA dodecamer duplex, we have modeled a duplex of an all-C3'
163 five examples of A-tract DNA oligonucleotide dodecamer duplexes for which crystal structures are avai
164 their behavior in the context of hexamer and dodecamer duplexes were carried out, with comparison to
165 CD spectroscopic studies of two related DNA dodecamer duplexes, d(CGCAAATTTGCG)(2) (A(3)T(3)) and d(
166 nm) clearly detects two transitions for this dodecamer, each giving a pronounced change in ellipitici
167 ain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been dete
169 analysis of the pH dependence of the trimer-dodecamer equilibrium revealed a near physiological pK(a
171 tationally investigate four classes of Abeta dodecamers: fibril, fibril oligomer, prefibril/preglobul
172 hways and provide a candidate in the Abeta42 dodecamer for the primary toxic species in Alzheimer's d
173 ls that tightly spooled DNA about the portal dodecamer forces a conformation that is significantly di
174 tution d-Pro36-l-Pro37 abolished hexamer and dodecamer formation by Abeta42 and produced an oligomer
176 A cocrystallization experiment in which a dodecamer-forming peptide recruits a hexamer-forming pep
180 rotection (hydroxyl radical) for Dps protein dodecamers from Bacillus anthracis (Ba) since crystal st
186 onformational features of the Dickerson-Drew dodecamer in both the solid state and the aqueous liquid
187 w of the conformational space sampled by the dodecamer in solution and permit one to analyze fluctuat
188 solution structure of an oxaliplatin-GG DNA dodecamer in the AGGC sequence context by 2D NMR studies
189 The precursor form of API assembles into a dodecamer in the cytosol and maintains this oligomeric f
190 eaved recombinant rat and natural human SP-D dodecamers in a time- and dose-dependent manner, which w
192 on distribution around (5'-CGCGCGCGCGCG-3')2 dodecamers in solution in B-DNA, A-RNA, Z-DNA and Z-RNA
193 tructures for cisplatin-GG and undamaged DNA dodecamers in the AGGC sequence context and have compare
194 re, six DHO and six ATC chains form a hollow dodecamer, in which the 12 active sites face an internal
195 stabilize the bend direction in the A-tract dodecamers include propeller twisting of AT base-pairs,
196 , and activation, we aimed to dissociate the dodecamers independently of DNA and to analyze HOCl-depe
197 cromolecules attached to both ends of an mPE dodecamer induce the foldamer to collapse into a presume
198 portal monomer and dodecamer, and we fit the dodecamer into the cryo-electron microscopy density of t
199 g of HypT to DNA induces dissociation of the dodecamers into dimers and tetramers, thus forming the D
205 sequence, and crystal form as the "Dickerson dodecamer", is refined against a complete, low-temperatu
206 simulations, when compared with those of the dodecamer itself, show that incorporation of the analog
209 activation of HSP16.9 occurs by shifting the dodecamer <--> dimer equilibrium in favor of free dimers
211 determined for double helix formation by DNA dodecamers near 25 degrees C are in the range of 0.72-0.
213 surface, suggesting that the assembly of the dodecamer occurs through head-to-tail interactions of th
214 iana, the overall architecture of which is a dodecamer of (beta/alpha)8 barrels, similar to the major
215 Lumbricus terrestris hemoglobin is a 213 kDa dodecamer of four chemically distinct globin chains, con
216 10.5, 6.3, 5.0, and 4.2 nm, identified as a dodecamer of globin chains ([a+b+c]3d3, 213 kDa), the di
217 t be due to the oligomeric nature of EmrE, a dodecamer of helices was constructed based on the result
218 G4T4G4-Lys-NH2 (G-PNA) hybridizes with a DNA dodecamer of homologous sequence to form a four-stranded
219 x contains the portal protein, a gear-shaped dodecamer of radially disposed subunits with a central c
221 2-A crystal structure, PdxS is a cylindrical dodecamer of subunits having the classic (beta/alpha)8 b
224 virus type 1 (HSV-1) portal is composed of a dodecamer of UL6 protein molecules whose incorporation i
226 ligomers ranging in size from dimers through dodecamers of 4 kDa monomeric Abeta have been resolved i
227 Higher resolution mapping using a set of dodecamers of overlapping sequences from the C-terminal
228 o three modifications were incorporated into dodecamers of RNA [AAGA GGG AUGAC] resulting in thermal
231 denaturation, and spectroscopic studies with dodecamers of the form d(ATTA-XGCX-TAAT) and their self-
232 rmation of a set of 30 octamer, decamer, and dodecamer oligomers for which high-resolution crystal st
233 roscopy using a series of self-complementary dodecamer oligonucleotides that contain the sequence mot
235 tions on lectin activity, incubation of SP-D dodecamers or murine lavage with peroxynitrite decreased
236 0-50 nm diameter, consisting of eight hetero-dodecamers) or three small rings (10-20 nm diameter, eac
238 ndividuals responded to the atypically large dodecamer peptide (169)EECDSELEIKRY(180), which encompas
240 n and yellow fluorescent proteins fused by a dodecamer peptide encompassing a natural cleavage site.
242 ound more stably to HLA-B*18:01 than did the dodecamer peptide, whereas, conversely, HLA-B*44:03 boun
244 otif demonstrated that nonamer, decamer, and dodecamer peptides containing the sequence KCDICTDEY (re
247 We discovered that Abeta42 hexamers and dodecamers quickly become the dominant oligomers after p
249 y element in Vbeta6.7 should be considered a dodecamer rather than a decamer and that it confers stro
250 rmamidopyrimidine lesions reduce the T(M) of dodecamers relative to their unmodified nucleotide count
251 s identified to date contain expansions of a dodecamer repeat located upstream of the transcription s
252 genotyping assay capable of detecting single dodecamer repeat unit differences on an automated DNA se
253 We furthermore suggest that expansion of a dodecamer repeat, which we predict to have very high fle
256 tudies show that the minor groove in an AATT dodecamer responds to local sodium ion positions and is
257 spectroscopy of the modified Dickerson-Drew dodecamer revealed that the conformation of the duplexes
258 and of a single dU(8) in the Dickerson-Drew dodecamer revealed that the modifications are essentiall
261 xpectedly we found that recombinant rat SP-D dodecamers selectively induce the biosynthesis of collag
262 e synthetic ODNs based on the Dickerson Drew dodecamer sequence (CGCGAAT*T*CGCG) were examined where
264 arcin and ricin, requires a nearly universal dodecamer sequence that folds into a G-bulged cross-stra
265 terminal His-tag on PrxIII markedly enhances dodecamer stability, particularly apparent in its oxidis
266 In the presence of divalent metal ions, the dodecamers "stack" along their six-fold axis of symmetry
270 limits would include the outermost repeated dodecamers suggested as arm recognition sites by S. J. S
271 similar to the outer surface of the soluble dodecamer, suggesting that the VacA surface in contact w
272 nits are required to form an alpha(6)beta(6) dodecamer that specifically catalyzes the decarboxylatio
273 Z3dU was >5 A, which indicated that in this dodecamer the Z3dU amino group did not participate in a
274 A X-ray structure of a double-stranded B-DNA dodecamer (the Dickerson Dodecamer, DDD, [d(CGCGAATTCGCG
275 rther associate into hexamers, octamers, and dodecamers: the hexamers are trimers of dimers; the octa
276 indings indicate that API is maintained as a dodecamer throughout its import and will be useful to st
279 e TnrA dimer and causing an unprecedented GS dodecamer-to-tetradecamer conversion, which concomitantl
280 dynamics study of 21 Casiopeinas with a DNA dodecamer using 10 mus of simulation time for each compo
281 en [Pt(ammine)(cyclohexylamine)]2+ and a DNA dodecamer, using the same sequence as previously reporte
283 The adenine in each A.T basepair of the dodecamer was labeled with 15N at the N6 position, and t
284 stribution of conserved surfaces in the PdxS dodecamer was used to predict a docking site for the glu
285 ion crystal structures of the Dickerson-Drew dodecamer was used to re-evaluate the deoxyribose pseudo
286 cent crystal and NMR structures of the EcoRI dodecamer, where an overall bend of seven degrees is dis
288 A X-ray structure of the DDD (Dickerson-Drew dodecamer), which has been covalently modified by the te
289 ecules within the hydration shell of a B-DNA dodecamer, which are of interest for many of its biochem
291 a reversible equilibrium between trimer and dodecamer with an equilibrium constant of approximately
292 r in solution, upon binding DNA, BAF forms a dodecamer with DNA bound at multiple discrete sites in t
293 ther known proteasome activator, PafE formed dodecamers with 12-fold symmetry, which required a glyci
294 rivatives yielded oligoadenylates as long as dodecamers with a regioselectivity for 3',5'-phosphodies
295 r dynamics simulations of double-helical DNA dodecamers with and without a single abasic (tetrahydrof
296 s to laterally aggregate and intertwine into dodecamers with elongated, twisted conformations contain
298 21-25 A revealed that all four isoforms were dodecamers with similar but highly unusual architecture.
300 The macrocycles range from a trimer to a dodecamer, with ring sizes from 24 to 114 atoms, and are
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