ライフサイエンスコーパス: dodecylphosphocholine

1 cterized, particularly for the lipid mimetic dodecylphosphocholine.

2 ng LMPC micelles versus micelles composed of dodecylphosphocholine.

3 ane-mimicking detergent micelles composed of dodecylphosphocholine.

4 This was achieved after solubilization by dodecylphosphocholine and purification in the presence o

5 in the presence of monomeric and micellar n-dodecylphosphocholine (C12-PN), a phosphatidylcholine an

6 2) binding an inhibitor recently obtained in dodecylphosphocholine detergent micelles.

7 an the NMR model obtained in the presence of dodecylphosphocholine detergent micelles.

8 re 22-23 A in diameter, composed of 51 +/- 4 dodecylphosphocholine detergent molecules.

9 resence of aqueous solutions of zwitterionic dodecylphosphocholine (DPC) and anionic sodium dodecylsu

10 SERCA, co-reconstituting the two proteins in dodecylphosphocholine (DPC) detergent micelles, a system

11 mbinant JX domain in aqueous solution and in dodecylphosphocholine (DPC) detergent.

12 -4 and GLP-1 by NMR in both the solution and dodecylphosphocholine (DPC) micelle-associated states.

13 ocking and further biological behaviors, the dodecylphosphocholine (DPC) micelle-bound conformations

14 membranes, we have reconstituted LL-37 into dodecylphosphocholine (DPC) micelles and determined its

15 glycero-3-phosphocholine (DMPC) vesicles and dodecylphosphocholine (DPC) micelles as membrane mimetic

16 s at the feet were investigated in water and dodecylphosphocholine (DPC) micelles by NMR spectroscopy

17 structure of the construct was determined in dodecylphosphocholine (DPC) micelles by solution NMR spe

18 e structure of the protein when dissolved in dodecylphosphocholine (DPC) micelles consists of several

19 domain of ADAM10 (A10TmCp) reconstituted in dodecylphosphocholine (DPC) micelles exhibits much great

20 oism spectroscopy of synthetic M2 protein in dodecylphosphocholine (DPC) micelles indicated that appr

21 NMR studies in dodecylphosphocholine (DPC) micelles suggested that the

22 water and in sodium dodecylsulfate (SDS) and dodecylphosphocholine (DPC) micelles were studied by 2D

23 ylcholine spin-labels were incorporated into dodecylphosphocholine (DPC) micelles, and the reduction

24 experiments on these peptides solubilized in dodecylphosphocholine (DPC) micelles, we found that the

25 content in 30% trifluoroethanol (TFE) or in dodecylphosphocholine (DPC) micelles, which mimic hydrop

26 n two membrane-mimetic environments, SDS and dodecylphosphocholine (DPC) micelles.

27 M reconstituted in lipid bilayers as well as dodecylphosphocholine (DPC) micelles.

28 y NMR spectroscopy in an aqueous solution of dodecylphosphocholine (DPC) micelles.

29 n the presence of trifluoroethanol (TFE) and dodecylphosphocholine (DPC) micelles.

30 ly3 through Arg9 when bound to perdeuterated dodecylphosphocholine (DPC) micelles.

31 A high selectivity for DOPC over dodecylphosphocholine (DPC) was also observed, and compu

32 The propensity of dodecylphosphocholine (DPC), a detergent widely utilized

33 the presence of the zwitterionic detergent n-dodecylphosphocholine (DPC).

34 Titration of dodecylphosphocholine into a solution of PrP110-136 reve

35 Calcium titrations, together with dodecylphosphocholine micelle experiments, confirmed tha

36 ubsequent docking of an EqtII monomer onto a dodecylphosphocholine micelle, followed by 400 ns of all

37 MPERp structures solved in dodecylphosphocholine micelles and 25% 1,1,1,3,3,3-hexaf

38 inin fusion peptide in two differently sized dodecylphosphocholine micelles and a palmitoyl oleoyl ph

39 ta B1 and kalata B2 (and various mutants) to dodecylphosphocholine micelles and phosphoethanolamine-c

40 dopt an alpha-helical secondary structure in dodecylphosphocholine micelles and small unilamellar ves

41 ally active phospholamban in lipid-mimicking dodecylphosphocholine micelles as determined by multidim

42 a peptide comprising the LD anchor bound to dodecylphosphocholine micelles as LD mimic reveals that

43 -sn-glycero-3-[phospho-rac-(1-glycerol)] and dodecylphosphocholine micelles at concentrations (200-50

44 tructure of 1 or CCK-8(s) in the presence of dodecylphosphocholine micelles at pH 5.0 and 35 degrees

45 NMR structures in dodecylphosphocholine micelles at pH 7.0 and 5.5 reveale

46 studied the dynamics of this domain bound to dodecylphosphocholine micelles by homo- and heteronuclea

47 he structure of the transmembrane segment in dodecylphosphocholine micelles by liquid-state NMR and f

48 n, has been determined at high resolution in dodecylphosphocholine micelles by NMR.

49 e transmembrane domain of human LAMP-2A in n-dodecylphosphocholine micelles by nuclear magnetic reson

50 ture of CCK(A)-R(329-357) in the presence of dodecylphosphocholine micelles consists of three alpha-h

51 Monodispersed preparations of alphaT68M1 in dodecylphosphocholine micelles demonstrate high-affinity

52 ally reconstituted SERCA with labeled PLN in dodecylphosphocholine micelles for high-resolution NMR s

53 hormone receptor (PTH1R) in the presence of dodecylphosphocholine micelles have been determined usin

54 ssociation free energy of glycophorin A in N-dodecylphosphocholine micelles is in good agreement with

55 NMR data for full-length synaptobrevin in dodecylphosphocholine micelles reveals two transient hel

56 We show that in dodecylphosphocholine micelles the structure of the BNIP

57 kbone dynamics of monomeric phospholamban in dodecylphosphocholine micelles using (1)H/(15)N heteronu

58 fatide-binding motifs has been determined in dodecylphosphocholine micelles using NMR spectroscopy.

59 The NMR solution structure of TriA1 in dodecylphosphocholine micelles with lipid II has been de

60 ement of the FYVE domain with PtdIns(3)P and dodecylphosphocholine micelles yields a 6-fold enhanceme

61 tructure of synthetic pardaxin Pa4 in sodium dodecylphosphocholine micelles, as determined by (1)H so

62 mately 1.3 kcal/mol more favorable than in N-dodecylphosphocholine micelles, consistent with availabl

63 ublished solution NMR structure of OmpG in n-dodecylphosphocholine micelles, presumably due to confor

64 three-dimensional structures of in H(2)O and dodecylphosphocholine micelles, showing the detailed con

65 th the known NMR structure of the peptide in dodecylphosphocholine micelles, the N-terminal helical s

66 Under conditions in which it is monomeric in dodecylphosphocholine micelles, the protein consists mai

67 After transfer into dodecylphosphocholine micelles, the solution structure o

68 In the presence of dodecylphosphocholine micelles, the structure of the rec

69 but underwent high affinity association with dodecylphosphocholine micelles, where it adopted an orde

70 f caveolin-1 (Cav1(62-178)) was a monomer in dodecylphosphocholine micelles.

71 2 (R284-G346) binds to the membrane mimetic, dodecylphosphocholine micelles.

72 ide exists in a monomer-dimer equilibrium in dodecylphosphocholine micelles.

73 s-PtdIns(3)P analogues into membrane-mimetic dodecylphosphocholine micelles.

74 cture of an unphosphorylated PLN pentamer in dodecylphosphocholine micelles.

75 at pH 6.0 and 37 degrees C in perdeuterated dodecylphosphocholine micelles.

76 died by (1)H and (15)N solution-state NMR in dodecylphosphocholine micelles.

77 s were included and structures determined in dodecylphosphocholine micelles.

78 pe tachyplesin I and TPY4 in the presence of dodecylphosphocholine micelles.

79 representing the M2 transmembrane segment in dodecylphosphocholine micelles.

80 of in a membrane-mimicking environment using dodecylphosphocholine micelles.

81 oth the cis and trans isoforms of 1 bound to dodecylphosphocholine micelles.

82 d in both aqueous solution and when bound to dodecylphosphocholine micelles.

83 ng 1H NMR and CD, in trifluoroethanol and in dodecylphosphocholine micelles.

84 With the protein in DPC (dodecylphosphocholine) micelles, we used manganous ion a

85 In the presence of dodecylphosphocholine, MIR-WaaG was observed to adopt a

86 Iodine-125-12-[m-iodophenyl]-dodecylphosphocholine (NM-324) has been shown to accumul

87 micelles of the bolaamphiphiles with either dodecylphosphocholine or beta-n-decyl maltoside were mor

88 The detergent dodecylphosphocholine, or DPC, proved especially effecti

89 lar POPC vesicles by dialyzing the detergent dodecylphosphocholine out of mixed micellar mixtures.

90 he present investigation, we demonstrate how dodecylphosphocholine severely alters the structure as w

91 or solubilizing membrane proteins, including dodecylphosphocholine, the lysolipid 1-palmitoyl-2-hydro

92 8-198], determined in a micellar solution of dodecylphosphocholine to mimic the membrane environment,

93 and saline solutions and in the presence of dodecylphosphocholine), we observe no evidence for a U-s

94 tII at the critical micelle concentration of dodecylphosphocholine, we have mapped the lipid-binding