ライフサイエンスコーパス: dog

1 whether a dog would be a successful service dog.

2 asthma did not live in a house with a cat or dog.

3 inciple and making the device "sniff" like a dog.

4 site in southern Russia, were identified as dogs.

5 e improved control of H3N8 CIV infections in dogs.

6 type immune response in mice, hamsters, and dogs.

7 Ust'-Polui skulls were clearly identified as dogs.

8 sh between naturally infected and vaccinated dogs.

9 ecessive congenital myopathies in humans and dogs.

10 good oral bioavailability in mice, rats, and dogs.

11 d golden retriever muscular dystrophy (GRMD) dogs.

12 harmacokinetic parameters in mice, rats, and dogs.

13 ) are available for the prevention of CIV in dogs.

14 an urban (P = 0.002) or suburban (P = 0.001) dogs.

15 tive, compared with 1.8% of the nondiarrheic dogs.

16 ring acute oral lipid challenges in rats and dogs.

17 lars and first molars were extracted in five dogs.

18 n innovative approach to mass vaccination of dogs.

19 ceramic rods implanted in the jaws of beagle dogs.

20 the epicardial surface of the left atrium in dogs.

21 inea pigs, rabbits, and hamsters; and female dogs.

22 ecessive congenital ichthyosis in humans and dogs.

23 an avian-origin virus that adapted to infect dogs.

24 ecifics, wolves should cooperate better than dogs.

25 ry open angle glaucoma and ectopia lentis in dogs.

26 ined in rodents, primates, humans, pigs, and dogs.

27 edles inserted into the left ventricles of 6 dogs.

28 uces SMOC2 gene expression in brachycephalic dogs.

29 n gene expression compared to control normal dogs.

30 mutation in BMP3 among small brachycephalic dogs.

31 ximately 99% of the cases are transmitted by dogs.

32 What predicts success as a guide dog?

33 -1.26; 2 dogs: 0.79; 95% CI, 0.54-1.15; >/=3 dogs: 0.50; 95% CI, 0.23-1.12; compared with nonexposed

34 dog: adjusted HR, 1.07; 95% CI, 0.91-1.26; 2 dogs: 0.79; 95% CI, 0.54-1.15; >/=3 dogs: 0.50; 95% CI,

35 1, EXO-1, SLX-1 and FAN-1 nucleases, and the DOG-1 (FANCJ) helicase in ICL resolution, influenced by

36 were positive for CD117 (c-kit) (Fig 1B) and DOG-1(Fig 1C).

37 ivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.

38 The prevalence in dogs (60 of 2,422) was 2.5%.

39 current chemical trace detection technology, dogs actively sniff to acquire an odor sample.

40 The size of the dog (adjusted HR per 10-cm increase in height, 0.96; 95%

41 No association was found between exposure to dogs (adjusted hazard ratio [HR], 1.00; 95% CI, 0.86-1.1

42 -1.06) or number of dogs in the household (1 dog: adjusted HR, 1.07; 95% CI, 0.91-1.26; 2 dogs: 0.79;

43 Dog allergen exposure did not show such interaction.

44 es, cat allergen in 420 samples (94.8%), and dog allergen in 366 samples (82.6%).

45 cat and dog ownership from birth and cat and dog allergen levels in bedding at age 1 year.

46 Mite, mouse, cat, and dog allergens were mostly higher in DCC than in homes.

47 High-titer IgE antibodies to cat and dog allergens were strongly associated with the diagnosi

48 s orally bioavailable in the mouse, rat, and dog and allows a sustained delivery of the biologically

49 Exposure to dog and cat allergens in DCC often reached levels of hou

50 rphometric study using ontogenetic series of dog and wolf crania, and samples of dogs with relatively

51 sis correctly classifies 99.5% of the modern dog and wolf mandibles.

52 prevalence of Salmonella in a population of dogs and cats in the United States visiting veterinary c

53 decline in prevalence of Salmonella-positive dogs and cats over the last decades and identifies consu

54 lonizes the nares and anal mucosa of healthy dogs and cats.

55 -positive E. coli shared among farms, flies, dogs and farmers, providing direct evidence of carbapene

56 cally and financially devastating disease in dogs and further understanding of the ever-growing compl

57 he unique interspecific relationship between dogs and humans, two highly social but evolutionarily di

58 and large mammals, including rodents, pigs, dogs and humans.

59 ecanoate (C12) derivatives were evaluated in dogs and in minipigs, at a dose of 5mg-eq. nalmefene/kg

60 the hard palate is common to brachycephalic dogs and is a welfare concern, as the incidence of respi

61 ied from 250BCE to 150CE, were identified as dogs and none of the 20 Ivolgin mandibles, an Iron Age s

62 However, the potential for coinfection of dogs and possible reassortment of human and other animal

63 described the pivotal roles of domesticated dogs and Rhipicephalus sanguineus sensu lato (brown dog

64 o assess the association between exposure to dogs and risk of type 1 diabetes in childhood.

65 or the prevention and control of H3N8 CIV in dogs and suggest the need for a new LAIV for the control

66 ested in dose escalation studies in rats and dogs and was found to induce cholinergic AEs and convuls

67 o question, and rather support the idea that dogs' and wolves' different social ecologies played a ro

68 rgens, including rat, mouse, cockroach, cat, dog, and dust mites, measured in dust samples collected

69 d health of Snuppy, the world's first cloned dog, and its somatic cell donor, Tai, a male Afghan houn

70 d in obsessive-compulsive disorder in human, dog, and mouse.

71 s, others are apparently resistant (rabbits, dogs, and horses) to the same agent.

72 ficacious antitumor responses in mice, rats, dogs, and humans.

73 fluenza, a contagious respiratory disease in dogs, and include the equine-origin H3N8 and the avian-o

74 tudies after administration of 1 to rodents, dogs, and monkeys.

75 e transfer of H3N8 equine influenza virus to dogs; and the H3N2 CIV, which is an avian-origin virus t

76 Dogs are a a potential mixing vessel for avian and mamma

77 cordingly with our results, we conclude that dogs are a valuable animal model of adult neurogenesis i

78 it benefit of the canine is compelling since dogs are an important part of our culture.

79 Guide dogs are particularly suited to research on these questi

80 The current study is therefore evidence that dogs are sensitive to the human's attentional state when

81 review the importance of sheltered and stray dogs as reservoirs of zoonotic parasites in different pa

82 ucose clamp experiments conducted in healthy dogs, as plasma glucose was lowered stepwise from 280 mg

83 l face transplant in Amiens (France) after a dog attack had left her face severely disfigured.

84 e likely responsible for these results, with dogs' avoidance of potential competition over the appara

85 The genetic component of dog behavior is supported by between-breed differences a

86 ffects of environmental/human factors on the dogs' behaviour are hard to discern from their genetic h

87 al but arousing stimulus, did not affect the dogs' behaviour.

88 Dog biscuits were evaluated for palatability and ability

89 During the study period, 1478 dog bites were reported to HARSP for assessment.

90 remains and having been the centre of modern dog breed creation.

91 Each dog breed is normally treated as a homogeneous group, ho

92 OS is common in large dog breeds and is genetically inducible in mice, making

93 Hairless dog breeds show a form of ectodermal dysplasia character

94 hose of consistently younger wolves, even in dog breeds that do not exhibit a 'juvenilized' morpholog

95 r of studies have reported differences among dog breeds with respect to their genetic profile, cognit

96 verall similarity of the skull shape of some dog breeds with that of juvenile wolves begs the questio

97 e are largely similar in wolves and domestic dogs, but differ in two ways.

98 atched, diabetic (n = 6) and healthy (n = 6) dogs by liquid chromatography-mass spectrometry (LC-MS)

99 New research suggests that dogs can imitate recently encountered actions using epis

100 mestication: the cranial morphology of adult dogs cannot simply be explained as either neomorphic or

101 (Perissodactyla), cow (Cetartiodactyla), and dog (Carnivora), and extracted among 162,000 preselected

102 rns in the COPSAC2000 birth cohort data: (1) dog/cat/horse, (2) timothy grass/birch, (3) molds, (4) h

103 helicidins, including human, mouse, pig, and dog cathelicidins, which lack antimicrobial activity und

104 Toxocara canis, T. cati, and T. vitulorum of dogs, cats and ruminants respectively, is recognized as

105 characteristics of the disease in humans vs dogs, cats, and horses are most often caused by similar,

106 Canine influenza is a respiratory disease of dogs caused by canine influenza virus (CIV).

107 Canine influenza is a respiratory disease of dogs caused by two CIV subtypes, the H3N8 and H3N2 virus

108 Of note, the current assemblies of the dog, CF 3.1 and the sheep, OA 3.1, genomes contain 264 a

109 33 dogs completed service training and were matched with a

110 Much of the fossil record for dogs consists of mandibles.

111 Adult-young dogs contained migratory cells capable to expand and dif

112 Thus, dogs continue to represent an important reservoir for zo

113 minantly share ancestry with modern European dogs, contradicting a previously suggested Late Neolithi

114 gene fusion partners and mechanisms in human-dog corresponding tumors and allows for selection of tar

115 f predation mitigation strategies for foxes, dogs, coyotes, wolves, bobcats, mountain lions, bears, a

116 and serum chemistries remained normal in all dogs (cumulative 6.4 years).

117 to filter gene signatures between human and dog datasets based on strong co-expression patterns.

118 ogic link with these disorders, confirm that dogs deficient in HACD1 are relevant models, and strengt

119 of high ambient temperatures on African wild dog demography, indicating that this species, which is a

120 Both dogs demonstrate continuity with each other and predomin

121 Diabetic dogs demonstrated significant upregulation of glycolysis

122 specifics and found that wolves outperformed dogs, despite comparable levels of interest in the task.

123 ly link thioesterase domains in a double hot dog dimer.

124 Secondly, do dogs display similar facial movements to humans when rea

125 sought to answer two questions: Firstly, do dogs display specific discriminatory facial movements in

126 We found that dogs displayed distinctive facial actions depending on t

127 Twelve rectal-swab specimens from dogs displaying clinical signs consistent with parvovira

128 f emotional expression across mammals, since dogs do not display human-like facial expressions.

129 the classification of the UP6571 skull as a dog (Dog Posterior Probability = 1.0) was not supported

130 The key to our understanding of dog domestication may lie in a closer comparative examin

131 sing our oldest dog, we narrow the timing of dog domestication to 20,000-40,000 years ago.

132 in patterns of development and growth during dog domestication.

133 recent hypothesis proposing dual origins of dog domestication.

134 omplex nature of evolutionary changes during dog domestication: the cranial morphology of adult dogs

135 nure pooled samples of cats, chickens, cows, dogs, ducks, pigs, and pigeons.

136 To determine whether exposure to dogs during the first year of life is associated with th

137 Indeed in dog dyads it was also less likely that both members simu

138 he training and imaging were performed in 49 dogs entering service training at 17-21 months of age.

139 Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeol

140 those domestication hypotheses that suggest dogs evolved greater cooperative inclinations into quest

141 Second, at any given age, juvenile dogs exhibit skull shapes that resemble those of consist

142 Sheltered and stray dogs, exposed to zoonotic parasites, including protozoa,

143 We investigated whether domestic dog exposure affected the risk of atopic dermatitis in c

144 We investigated interactions between cat and dog exposure and single nucleotide polymorphism rs721638

145 ), demonstrating interaction between cat and dog exposure and the rs7216389 genotype (adjusted P = .0

146 Cat and/or dog exposure from birth was associated with a lower prev

147 The effect of dog exposure on the risk of children developing allergic

148 Dog exposure was identified in 102 035 children (12.1%).

149 association of register-derived measures of dog exposure with childhood type 1 diabetes was identifi

150 adjusted HR of 0.71 (95% CI, 0.43-1.17) for dog exposure.

151 ent study, we aimed to test whether domestic dog facial expressions are subject to audience effects a

152 , to quantify and compare human and domestic dog facial expressions in response to emotionally-compet

153 In dogs, facial form is stunningly diverse.

154 t blaNDM quickly contaminates flocks through dogs, flies and wild birds.

155 aled that each protein subunit harbors a hot dog-fold and that the TE6 enzyme forms a hexamer with D3

156 dors, we are more sensitive than rodents and dogs for some odors, we are capable of tracking odor tra

157 ndible is not reliable for identifying early dog fossils.

158 ce the genomes of an Early and End Neolithic dog from Germany, including a sample associated with an

159 nine high-density (cHD) SNP genotyping of 28 dogs from 3 breeds to compare the SNP and linkage disequ

160 Three dogs from each group were euthanized and tissue collecte

161 ation analyses in GSDs combined with control dogs from five breeds with low-risk for CAD revealed the

162 discriminate samples from homes with cats or dogs from those without were calculated using receiver-o

163 exed by caudate activity, successful service dogs generalize associations to hand signals regardless

164 0-240 min, 2 groups of conscious dogs (n = 9 dogs/group) received a duodenal infusion of glucose (GLC

165 hypothesis that muscle from HACD1-deficient dogs has membrane abnormalities in common with CNMs with

166 Early-life exposure to cats and dogs has shown diverging associations with childhood ast

167 ber of domestication hypotheses suggest that dogs have acquired a more tolerant temperament than wolv

168 ition and two domains of social cognition of dogs have been affected by domestication and ontogeny.

169 Dogs have been demonstrated to seroconvert in response t

170 To test the hypothesis that diabetic dogs have similar metabolomic perturbations to humans wi

171 unique serovars were identified, with three dogs having two serovars present.

172 Expression of hNTCP in mouse, rat, and dog hepatocytes permits HDV infection but does not allow

173 breed comparing DM-affected and -unaffected dogs homozygous for the SOD1 mutation.

174 Diarrhea was present in only 55% of positive dogs; however, 3.8% of the all diarrheic dogs were posit

175 he differences among different beings (e.g., dogs, humans, robots, God) but not how people parse ment

176 e whether associations between living with a dog in the first year of life and allergic outcomes vary

177 Whether the child lived with an indoor dog in the first year of life was assessed through inter

178 Here we tested similarly raised wolves and dogs in a cooperative string-pulling task with conspecif

179 is CIV has caused thousands of infections in dogs in multiple states.

180 eight, 0.96; 95% CI, 0.86-1.06) or number of dogs in the household (1 dog: adjusted HR, 1.07; 95% CI,

181 luenza A virus subtypes has been reported in dogs in the last 16 years: the canine influenza viruses

182 We observed that wolves outperformed dogs in their ability to follow causal cues, suggesting

183 CIV subtypes responsible for influenza in dogs include H3N8, which originated from the transfer of

184 To succeed as a guide dog, individuals must accomplish complex navigation and

185 e total GLC infusion rate was 14% greater in dogs infused with GLC than in those receiving SAL (AUC36

186 In particular, the experiment of Pavlov's dog is successfully demonstrated.

187 Long bone length in dogs is a unique example of multiple disease-causing ret

188 Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and

189 and ocular trauma observed in this class of dogs is highly correlated with their skull form.

190 genetic architecture of behavioral traits in dogs is of great interest to owners, breeders, and profe

191 Dog keeping was not significantly inversely associated w

192 Cone morphology of the dogs lacking cone ERG are truncated with shortened outer

193 The African wild dog (Lycaon pictus), a tropical species, exhibits few of

194 he present study, donor/recipient pairs were dog lymphocyte antigen DR-B incompatible (88% of the pai

195 n canine and human V-SVZ indicating that the dog may be better representative of neurogenic events in

196 Dogs may be beneficial in reducing cardiovascular risk i

197 demonstrated that successful methods in our dog model are transferable to man.

198 augmentation therapy in a CNGbeta1-deficient dog model to evaluate potential translation to patients.

199 relative to control in a diet-induced obese dog model, suggesting the importance of systemic inhibit

200 ction and preserved retinal structure in the dog model.

201 CNGB1-deficient RP patients and mouse and dog models had a similar phenotype characterized by earl

202 e effects of MSC administration in mouse and dog models of chronic infections associated with biofilm

203 red human phenotypes with those of mouse and dog models of the disease.

204 roductive success, drawing on long-term wild dog monitoring data from sites in Botswana (20 degrees S

205 asma membranes of nucleated cells of rodent, dog, monkey, and human origin; increase ion permeability

206 creased morbidity and mortality occurring at dog mushing kennels in the area.

207 ental effects, we compared these dogs to pet dogs (n = 12) living in human families.

208 ion, we compared captive wolves (n = 12) and dogs (n = 14) living in packs under the same conditions.

209 ed from humans (n = 49), mice (n = 103), and dogs (n = 34) were generated using RNA sequencing.

210 From 0-240 min, 2 groups of conscious dogs (n = 9 dogs/group) received a duodenal infusion of

211 In both mice and dogs, no-observed-adverse effect level (NOAEL) was obser

212 ing, fMRI responses were measured while each dog observed hand signals indicating either reward or no

213 imal sources we considered chicken, pig, pet dog or cat, cattle, and poultry other than chicken.

214 il canid mandibles be reliably identified as dogs or wolves?

215 nd failure of early inhibitor discovery have dogged our standing with the pharmaceutical industry and

216 Having a parent who was registered as a dog owner during the child's first year of life.

217 In single- and multiple-person households, dog ownership (13.1%) was associated with lower risk of

218 In conclusion, dog ownership appears to be associated with lower risk o

219 Exposures included cat and dog ownership from birth and cat and dog allergen levels

220 In single-person households, dog ownership was inversely associated with cardiovascul

221 We aimed to investigate the association of dog ownership with incident cardiovascular disease (CVD)

222 gnificantly lower in diabetic versus healthy dogs (P < 0.05) with the exception of the branched chain

223 Random forest classification identified 5/6 dogs per group correctly with overall out of bag error r

224 Dogs performed multiple short, high-speed, mostly unsucc

225 In both experimental preparations of normal dogs, pericardiotomy blunted the increase in LV end-dias

226 te that genetic variance can be detected for dog personality traits assessed using questionnaire data

227 Primary hepatocytes from mice, rats, dogs, pigs, rhesus macaques, and cynomolgus macaques wer

228 In a dog platelet transfusion model, we have evaluated other

229 Nevertheless, we predicted that wild dog populations might be sensitive to weather conditions

230 devastating effect in communities with dense dog populations.

231 classification of the UP6571 skull as a dog (Dog Posterior Probability = 1.0) was not supported by th

232 in preclinical and clinical trials with pet dogs prior to human trials, within the framework of pers

233 However, dogs produced different facial movements to humans in co

234 Dogs produced significantly more facial movements when t

235 astatic tumor extract given intravenously in dogs, produced significantly increased pancreatic and bi

236 erve a unique chromatin signature typical of DoG-producing regions, suggesting that readthrough trans

237 in phenotype and behaviour has developed in dogs, providing a model for understanding the developmen

238 usly pull the rope ends, leading to success, dogs pulled the ropes in alternate moments, thereby neve

239 nscriptome of two non-allelic forms of RP in dogs, rcd1 and xlpra2, at clinically relevant advanced s

240 compatible (88% of the pairs), and recipient dogs received up to 8 weekly treated transfusions from a

241 wer, indicating activation of the enzyme, in dogs receiving GLC compared with those receiving SAL.

242 )) during the clamp were markedly greater in dogs receiving GLC compared with those receiving SAL.

243 d) Botswana site coincided with falling wild dog recruitment.

244 cted increases in polymerase II occupancy in DoG regions after heat shock, supporting our findings.

245 The domestic dog represents one of the most dramatic long-term evolut

246 y sensitive to detect subclinically infected dogs, resulting in the vaccination of infected animals,

247 In mutant dogs, rod and cone photoreceptors have a sensory cilium,

248 provided for control practices based on the dog's risk of infection.

249 mcr-1 as marker genes), we sampled poultry, dogs, sewage, wild birds and flies.

250 abolomic profiles in diabetic versus healthy dogs shared similarities with those reported in human T1

251 storical museum sample of pedigreed hairless dog skulls by using ancient DNA extraction and present t

252 First, dog skulls show unique (neomorphic) features already sho

253 rtex, we developed a classifier based on the dogs' subsequent training outcomes.

254 on and temperament are associated with guide dog success.

255 Interestingly, DoGs tend to be produced in the vicinity of neighboring

256 ved to be considerably wider in primates and dog than in rodents, whereas rodents show evidence of a

257 abeled in same-language sentences ("Find the dog!") than in switched-language sentences ("Find the ch

258 iated with phenotypic traits in the domestic dog that has emerged as a model for Mendelian and comple

259 als, which may lead to disease in vaccinated dogs that are also infectious to sand flies.

260 rigorous demands, only approximately 70% of dogs that enter training ultimately achieve success.

261 n of the AMY2B gene characteristic of modern dogs that has previously been proposed as an adaptation

262 Unlike in the coated wild type dogs, the hairless dogs were characterised in both the m

263 the same materials in mouse subcutaneous and dog tibia implant models, we demonstrate that the in vit

264 Dog tick saliva contains polyvalent CC-chemokine binding

265 d Rhipicephalus sanguineus sensu lato (brown dog ticks) as drivers of epidemic levels of Rocky Mounta

266 es derived from 374 pedigree and mixed-breed dogs to dissect the genetics of skull form.

267 ited the knowledge that owners have of their dogs to generate a large dataset of personality traits i

268 ore developmental effects, we compared these dogs to pet dogs (n = 12) living in human families.

269 ee, gorilla, rhesus macaque, mouse, rat, and dog-to investigate epigenomic evolution.

270 lumbricoides, and the parasitic nematode of dogs, Toxocara canis.

271 ine (LAIV), which was attenuated in mice and dog tracheal, explants compared to CIV H3N8 wild type.

272 In rodents (mouse, rat) and dogs, transfer of hNTCP supports viral entry but additio

273 The dog tumor is not necessarily lethal, while the devil tum

274 From 360-600 min, the remaining dogs underwent a hyperinsulinemic (4x basal) hyperglycem

275 Living with a dog was associated with decreased odds of having >/= 1 p

276 e longevity of both the donor and the cloned dog was close to the median lifespan of Afghan hounds wh

277 The threshold level for homes with dogs was 75 ng/m(2) Can f 1 (96.8% sensitivity, 96% spec

278 Ownership of hunting breed dogs was associated with lowest risk of CVD.

279 d downstream of gene-containing transcripts (DoGs), was reported to result from transcriptional readt

280 ng for 36% of facial length variation in the dogs we tested.

281 librating the mutation rate using our oldest dog, we narrow the timing of dog domestication to 20,000

282 s from a Golden Retriever muscular dystrophy dog were transfected with the large-size PB transposon r

283 Rural dogs were also more likely to be Salmonella positive tha

284 e in the coated wild type dogs, the hairless dogs were characterised in both the mandibular and maxil

285 Dogs were euthanized after a 4-month healing period.

286 Atrioventricular blocked dogs were immunosuppressed, instrumented with VVI pacema

287 ive dogs; however, 3.8% of the all diarrheic dogs were positive, compared with 1.8% of the nondiarrhe

288 Salmonella-positive dogs were significantly more likely to have consumed raw

289 Dogs were trained to discriminate between 40 odours; the

290 Eleven male beagle dogs were used in the study.

291 rsonality focused on the evaluation of adult dogs where the potential effects of environmental/human

292 We presented dogs with an experimental situation in which a human dem

293 first isolation of L. (L.) amazonensis from dogs with clinical manifestations of visceral leishmania

294 Fourteen dogs with microembolization-induced HF were randomized t

295 In vivo testing was performed in 19 dogs with NFUS catheters positioned in 4 chambers.

296 eries of dog and wolf crania, and samples of dogs with relatively ancestral morphology and from diffe

297 Studies in pet dogs with spontaneous chronic multi drug-resistant wound

298 Dogs with X-linked hereditary nephropathy (XLHN) have a

299 However, the socioecology of wolves and dogs, with the former relying more heavily on cooperativ

300 he efficacy of fMRI for predicting whether a dog would be a successful service dog.