ライフサイエンスコーパス: domoic acid

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1 status epilepticus when naturally exposed to domoic acid.

2 , but not in animals treated with 0.75 mg/kg domoic acid.

3 not 24 or 48 h after injection of 3.0 mg/kg domoic acid.

4 chronic clinical signs of toxic exposure to domoic acid.

5 d receptor levels after sub-seizure doses of domoic acid (0-3.0 mg/kg) in rats using [3H]PK-11195 aut

6 n slices following short-term treatment with domoic acid (10 microM).

7 Domoic acid, 2.25 mg/kg i.p., caused stereotyped behavio

8 iverse neurotoxicants including kainic acid, domoic acid, 3-nitropropionic acid, Fluoro-Gold and ison

9 lides can increase photodegradation rates of domoic acid, a marine algal toxin, and dimethyl sulfide,

10 Parenterally administered domoic acid, a structural analog of the excitatory amino

11 Here we report effects of domoic acid administration on quantitative indicators of

12 glc decreased in entorhinal cortex following domoic acid administration with or without convulsions.

13 classic excitotoxic neurotoxins kainic acid, domoic acid, and NMDA; the therapeutic glutamate analog

14 ronal death following neuronal damage due to domoic acid are not completely defined.

15 lifornianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabilitation cen

16 onfirm that during excitotoxicity induced by domoic acid, calcineurin-Bcl-2 and calcineurin-1,4,5-ino

17 A food toxin (domoic acid) calibration curve was produced, with %CVs r

18 h selective enhanced MIP-based RTP probe for domoic acid (DA) detection.

19 Domoic acid (DA) is a naturally occurring neurotoxin kno

20 Domoic acid (DA) or vehicle were bilaterally injected wi

21 The amount of domoic acid (DA) present in the growth media and in the

22 was present and low levels of the neurotoxin domoic acid (DA) were detected in nearly all tested anim

23 This bloom was associated with production of domoic acid (DA), a neurotoxin that was also detected in

24 Domoic acid (DA), an excitatory amino acid produced by d

25 Ocean (66 degrees S) contain the neurotoxin domoic acid (DA), associated with the diatom Pseudo-nitz

26 ups: saxitoxin (STX), okadaic acid (OA), and domoic acid (DA), for PSP, DSP, and ASP, respectively.

27 ckish, and freshwater environments including domoic acid (DA), okadaic acid (OA, and analogues), saxi

28 echanisms in modulating the neurotoxicity of domoic acid (DomA), by using cerebellar granule neurons

29 Specifically, the effects of domoic acid excitotoxicity can be alleviated only with c

30 These results suggest that acute domoic acid exposure affects discrete brain circuits by

31 However, in rats that convulsed after domoic acid GFAP was significantly increased throughout

32 ence of regional- to basin-scale controls on domoic acid has not previously been presented.

33 Evidence of climatic regulation of domoic acid in shellfish over the past 20 y in the North

34 Domoic acid, in the absence of convulsions, decreased re

35 Domoic acid increased GFAP in the anterior portion of ce

36 Domoic acid induced late neuronal death and caspase-3-li

37 Domoic acid-induced convulsions affects limbic structure

38 n circuits by inducing convulsions, and that domoic acid-induced convulsions cause chronic effects on

39 Domoic acid is a potent neurotoxin produced by certain m

40 The timing of elevated domoic acid is strongly related to warm phases of the Pa

41 ]quinoxaline-7-sulfonamide and reproduced by domoic acid microinjection, suggesting that the inductio

42 or interference from other shellfish toxins (domoic acid, okadaic acid group).

43 Six to eight days after domoic acid or vehicle administration, the animals were

44 We present an applied domoic acid risk assessment model for the US West Coast

45 y: other common marine toxins (okadaic acid, domoic acid, saxitoxin, brevetoxin-3, and yessotoxin) do

46 In animals diagnosed with chronic domoic acid toxicosis, the fornix showed signs of altere

47 d with 1.5 and 3.0 mg/kg, but not 0.75 mg/kg domoic acid were significantly impaired in water maze pe

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