ライフサイエンスコーパス: dopachrome

1 ct against proteasomal inhibition induced by dopachrome.

2 and (p-hydroxyphenyl)pyruvate and converts D-dopachrome, a stereoisomer of naturally occurring L-dopa

3 catalyzed oxidation to generate aminochrome, dopachrome, and furanoquinone, respectively.

4 rwent tyrosinase-catalyzed oxidation to form dopachrome, and similar to aminochrome, proteasomal inhi

5 en shown that formation of (HO)2IndCOOH from dopachrome is catalyzed by dopachrome tautomerase, that

6 eceptors, OR) and phenylpyruvate tautomerase/dopachrome isomerase activity (MIF and DDT genes).

7 oxidase, phenol oxidase, and interleukin 1, dopachrome isomerase and other, as of yet unidentified,

8 note, molecular modeling of the substrate L-dopachrome methyl ester into the active site of MIF sugg

9 monitoring the tautomerase activity using l-dopachrome methyl ester or 4-hydroxyphenyl pyruvic acid

10 n of the non-naturally occurring D-isomer of dopachrome, phenylpyruvate, and certain catecholamines,

11 be the protein encoded by the homologous, D-dopachrome tautomerase (D-DT) gene.

12 ation inhibitory factor (MIF), its homolog D-dopachrome tautomerase (D-DT), and their common receptor

13 y factor (MIF) and its functional homolog, d-dopachrome tautomerase (d-DT), have protumorigenic funct

14 rine MIF and its only known family member, D-dopachrome tautomerase (D-DT), promote the expression of

15 ew inflammatory activity for extracellular d-dopachrome tautomerase (D-DT), the recruitment of neutro

16 Tyrosinase and dopachrome tautomerase (DCT) activities were found exclu

17 DOPAchrome tautomerase (Dct) functions downstream of tyr

18 The melanin synthesis enzyme dopachrome tautomerase (DCT) is involved in intracellula

19 carrying a tyrosinase minigene driven by the dopachrome tautomerase (Dct) promoter region.

20 cell development in transgenic mice from the dopachrome tautomerase (Dct) promoter.

21 inase, tyrosinase-related protein-1 (Tyrp1), dopachrome tautomerase (Dct), and LAMP1 and 3 localizati

22 essing neural precursor cells (line Ntva) or dopachrome tautomerase (DCT)-expressing melanoblasts (li

23 yrosinase-related protein-1 (TYRP1/gp75) and dopachrome tautomerase (DCT/TYRP2) belong to a family of

24 Recent work by others has described D-dopachrome tautomerase (DDT) as a functional homologue o

25 D-dopachrome tautomerase (DDT) is an enzyme that lacks phy

26 l-Dopachrome tautomerase (l-DCT), also called tyrosinase-r

27 yrosinase, melanocortin receptor (MC1R), and dopachrome tautomerase (TRP-2).

28 melanocytes, Tyr, Tyr-related protein 1, and dopachrome tautomerase accumulated in enlarged granules

29 also has been described recently to exhibit dopachrome tautomerase activity and to be structurally h

30 yphenylalanine oxidation drop rapidly, while DOPAchrome tautomerase activity increases and dihydroxyi

31 ne is the same as the catalytic site for the dopachrome tautomerase activity of MIF.

32 methyl ester (ISO-1), an inhibitor of MIF d-dopachrome tautomerase activity, reveals that ISO-1 bind

33 igens gp100 and tyrosinase-related protein 2/dopachrome tautomerase and increased protection from a l

34 cell development and pigmentation, including dopachrome tautomerase and tyrosinase.

35 The expression of the dopachrome tautomerase gene (Dct) and its protein produc

36 lite resident within an intron of the bovine dopachrome tautomerase gene.

37 s and for physiological investigations (e.g. dopachrome tautomerase in melanogenesis).

38 nder the regulation of a melanocyte-specific dopachrome tautomerase promoter.

39 enic line with Grm1 expression driven by the dopachrome tautomerase promoter.

40 nd of the melanogenic enzymes tyrosinase and dopachrome tautomerase, all major players in melanogenes

41 cy of an enhancer required for expression of dopachrome tautomerase, an enzyme that functions in mela

42 as tyrosinase, tyrosinase-related protein-1, dopachrome tautomerase, and Pmel17, are known, the funct

43 rophthalmia-associated transcription factor, dopachrome tautomerase, and tyrosinase promoters, leadin

44 osinase or on the mRNA levels of tyrosinase, dopachrome tautomerase, Pmel17, or MITF mRNA levels.

45 (HO)2IndCOOH from dopachrome is catalyzed by dopachrome tautomerase, that the melanogenic protein tyr

46 on of an early zebrafish melanoblast marker, dopachrome tautomerase.

47 tyrosinase, tyrosinase-related protein-1 and dopachrome tautomerase/tyrosinase-related protein-2 and

48 hat these basic residues are not involved in dopachrome tautomerization.

49 of eumelanin by catalyzing the conversion of dopachrome to 5,5-dihydroxyindole-2-carboxylic acid (DHI

50 ome, a stereoisomer of naturally occurring L-dopachrome, to 5,6-dihydroxyindole-2-carboxylic acid.

51 inhibition correlated with the presence of a dopachrome UV-visible spectrum.