ライフサイエンスコーパス: dopamine D4 receptor

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1 s designed through the modification of known dopamine D4 receptor agonist PD 168077.

2 A new series of dopamine D4 receptor agonists, 1-aryl-3-(4-pyridinepiper

3 New dopamine D4 receptor agonists, exemplified by (E)-1-(4-c

4 develop a new class of potent and selective dopamine D4 receptor agonists.

5 616 acts through antagonism of the host cell dopamine D4 receptor and subsequent repression of the ER

6 is a novel, highly selective radioligand for dopamine D4 receptors and may be used to investigate the

7 ridones and piperidines, including potential dopamine D4 receptor antagonists 2 and 3, that have been

8 ave reported that polymorphisms of the human dopamine D4 receptor (D4R) gene are associated with pers

9 Recently, retinal dopamine D4 receptors (D4Rs) have been implicated in mod

10 ric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently imp

11 In particular, the dopamine D4 receptor (DRD4) has been shown to moderate t

12 of L-750,667 bound specifically to the human dopamine D4 receptor expressed in HEK cells and saturati

13 d D3 receptors expressed in HEK293 cells and dopamine D4 receptors expressed in CHO cells.

14 The dopamine D4 receptor garnered a great deal of interest i

15 gnitive endophenotypes, and variation in the dopamine D4 receptor gene (DRD4) explains at least a por

16 th polymorphisms in some dopamine genes (the dopamine D4 receptor gene and the dopamine transporter g

17 lism in mice with targeted disruption of the dopamine D4 receptor gene.

18 How an optimal level of human dopamine D4 receptor (hD4R) is maintained in synaptic me

19 The dopamine D4 receptor in prefrontal cortex (PFC) plays a

20 and [3H]raclopride has been used to quantify dopamine D4 receptors in postmortem schizophrenic brain

21 One of the important targets of dopamine D4 receptors in prefrontal cortex (PFC) is the

22 )alkylamines with selective affinity for the dopamine D4 receptor is described.

23 ridin-5-ones with selective affinity for the dopamine D4 receptor is described.

24 These findings indicate that dopamine D4 receptors normally play a major role in regu

25 Activation of dopamine D4 receptors on photoreceptor cells reduces a l

26 of NMDA-type glutamate receptors by the PFC dopamine D4 receptor (one of the principal targets of an

27 icant nor consistent observation of striatal dopamine D4 receptors or D4-like binding sites was obser

28 receptors and may be used to investigate the dopamine D4 receptor population in the central nervous s

29 dicate that the decrease of cAMP elicited by dopamine D4 receptor stimulation may be secondary to dec

30 Dopamine and agonists of dopamine D4 receptors suppressed K(+)-stimulated uptake

31 Photoreceptor cells express dopamine D4 receptors that regulate cAMP metabolism.

32 ell death are, at least in part, mediated by dopamine D4 receptors via the regulation of cGMP-operate

33 The dopamine D4 receptor, which is enriched in PFC, has been

34 The dopamine D4 receptor, which is highly enriched in the PF

35 zole (36) is a nanomolar antagonist at human dopamine D4 receptors with > 500-fold selectivity over h

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