ライフサイエンスコーパス: dopaminergic

1 ittent ethanol exposure induces cellular and dopaminergic abnormalities in the adult prelimbic cortex

2 Dopaminergic activation increases expression of the heat

3 These findings suggest that song-triggered dopaminergic activation serves a dual function in social

4 Here we tested the idea that dopaminergic activity changes the pattern of connectivit

5 Dopaminergic activity limits this uncontrolled beta sync

6 sembly distribution is directed by tegmental dopaminergic activity.

7 atecholamine levels through interaction with dopaminergic, adrenergic and serotonergic system compone

8 presynaptic kappa-opioid receptors (KORs) on dopaminergic afferents and can negatively regulate dopam

9 aHCO3), NAC+NaHCO3, ascorbic acid, xanthine, dopaminergic agent, peripheral ischemic preconditioning,

10 controlled pharmacological fMRI study with a dopaminergic agonist (bromocriptine) and antagonist (sul

11 by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC).

12 of the inner plexiform layer (IPL) and from dopaminergic amacrine cells and GABAergic processes in t

13 Changing the relative number of dopaminergic and GABAergic AOB interneurons or locally i

14 they target Pax6 and Bcl11b to regulate the dopaminergic and GABAergic phenotypes.

15 uts across psychiatric disorders and engages dopaminergic and glutamatergic pathways that regulate mo

16 n show premotor neurochemical changes in the dopaminergic and non-dopaminergic systems.

17 finamide (an oral aminoamide derivative with dopaminergic and nondopaminergic actions) in levodopa-tr

18 ontribute to the particular vulnerability of dopaminergic and noradrenergic neurons to neurodegenerat

19 INTERPRETATION: Dopaminergic and serotonergic changes progress in a simi

20 Using PET, we assessed whether dopaminergic and serotonin transporter changes are simil

21 pharmacological manipulations targeting the dopaminergic and stress systems affect decision making i

22 standing of instrumental learning as well as dopaminergic and striatal network function across many m

23 molecular mechanisms that regulate midbrain dopaminergic axon growth and target innervation are less

24 represses Smad signalling to limit midbrain dopaminergic axon growth and target innervation.

25 new mechanism for the regulation of midbrain dopaminergic axon growth during central nervous system d

26 bryonic rodent midbrain during the period of dopaminergic axon growth, when BMP pathway components ar

27 erminal changes were selectively observed in dopaminergic axons in the dorsal striatum.

28 Cre-dependent genetic excision of KOR from dopaminergic, but not serotonergic neurons, also blocked

29 icity on D2R were not driven by variation in dopaminergic candidate genes.

30 mechanism links two cardinal features of PD: dopaminergic cell death and alpha-synuclein aggregation.

31 on vulnerability are hindered by the lack of dopaminergic cell death in alpha-synuclein transgenic mi

32 en exploited to recapitulate PD gene related dopaminergic cell loss.

33 rain and uncovered 16 candidates that modify dopaminergic cell loss.

34 brains, p11 mRNA expression was measured in dopaminergic cells from the substantia nigra.

35 evidence of morphologic abnormalities of the dopaminergic cells in mutant brains.

36 Dopaminergic cells were grafted in a manner designed to

37 then received intraputamenal grafts of fetal dopaminergic cells, control cerebellar cells, or vehicle

38 ed in mixed cerebrocortical cultures and N27 dopaminergic cells.

39 and synaptic-like vesicles in rat and human dopaminergic cells.

40 Lmx1a/b, Otx2, and Plxnc1 as determinants of dopaminergic circuit formation and should assist in engi

41 Until now, mechanisms involved in dopaminergic circuit formation remained largely unknown.

42 to avoid physical effort is independent from dopaminergic circuits and strengthen the general idea th

43 For CpG sites at genes of the dopaminergic (COMT, ANKK1) and the neurotrophic (BDNF, N

44 ession of optogenetic tools in neurons under dopaminergic control during a behavior of interest.

45 our procedure doesn't result in transfer of dopaminergic control from the ventral to dorsal striatum

46 tic features that are adapted to the dynamic dopaminergic control of pituitary prolactin secretion, a

47 ckout (Mapt(-/-)) mice develop age-dependent dopaminergic (DA) neuronal loss in the substantia nigra

48 Aldehyde dehydrogenase 1 (ALDH1A1)-positive dopaminergic (DA) neurons at the ventral substantia nigr

49 the development and maintenance of embryonic dopaminergic (DA) neurons in the midbrain.

50 ressful oscillations of Ca(2+) levels within dopaminergic (DA) neurons in the substantia nigra (SN),

51 Loss of dopaminergic (DA) neurons in the substantia nigra pars c

52 reward system involves increased activity of dopaminergic (DA) neurons in the ventral tegmental area

53 Dopaminergic (DA) neurons in the ventral tegmental area

54 Loss of dopaminergic (DA) neurons leads to Parkinson's disease;

55 Understanding how dopaminergic (DA) neurons of the substantia nigra pars c

56 ketamine elicits similar molecular events in dopaminergic (DA) neurons, known to be affected in mood

57 show that the En1 microdomain gives rise to dopaminergic (DA) neurons, whereas the Dbx1 microdomain

58 ate the expression of RGMa in midbrain human dopaminergic (DA) neurons.

59 be differentiated into mature and functional dopaminergic (DA) neurons.

60 bnormal development of ventral midbrain (VM) dopaminergic (DA) pathways, essential for motor and cogn

61 IGNIFICANCE STATEMENT Understanding midbrain dopaminergic (DAergic) neuron-selective vulnerability in

62 rative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra a

63 The Drosophila dopaminergic (DAergic) system consists of a relatively s

64 eptor availability together with presynaptic dopaminergic defects.

65 ks later, after behavioral and nigrostriatal dopaminergic deficits had developed, rats underwent STN-

66 arkinson-like phenotype associated with full dopaminergic depletion.

67 Thus, a dopaminergic disturbance may underpin drug-biased choice

68 Tourette syndrome (TS) prominently involves dopaminergic disturbances, but the precise nature of tho

69 bserved time-delineated dorsal raphe nucleus dopaminergic (DRN(DA)) activity upon exposure to arousal

70 se receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded

71 rch implicating the default mode network and dopaminergic dysfunction in ADHD.

72 nding of clinical conditions associated with dopaminergic dysfunction, such as psychosis.

73 EDS was also associated with presynaptic dopaminergic dysfunction, whereas biofluid markers at ye

74 que feature of PD that likely contributes to dopaminergic dysfunction.

75 Though dopaminergic dysregulation characterizes a number of neu

76 hese findings yield a new topography for the dopaminergic dysregulation in schizophrenia.

77 alretinin-positive neurons while suppressing dopaminergic fate in the postnatal dorsal lineage.

78 rter levels, but changes in other aspects of dopaminergic function are inconsistent.

79 Thus, we aimed to test whether dopaminergic function is altered in patients with a hist

80 riatum) in line with the hypothesis that the dopaminergic function is linked to treatment response.

81 nd childhood trauma, also affect presynaptic dopaminergic function.

82 nes, and the scarcity of imaging evidence on dopaminergic function.

83 f the physiological role of GDNF on striatal dopaminergic function.

84 genes involved in serotonergic, cholinergic, dopaminergic, GABAergic, and glutamergic synapse respons

85 orrelates of ADHD symptomatology and maps of dopaminergic gene expression.

86 erences in allele frequencies of variants in dopaminergic genes associated with dopamine D2/D3 recept

87 multiple neuronal systems, specifically the dopaminergic, glutamatergic, and gamma-aminobutyric acid

88 IG-1 [PAR-1(I)-like Gene], leads to abnormal dopaminergic head neuron numbers.

89 creen for C. elegans mutants with defects in dopaminergic head neuron specification or differentiatio

90 ham-1, pig-1 and apoptosis pathway genes in dopaminergic head neurons.

91 d in schizophrenia, including glutamatergic, dopaminergic, immune and antioxidant signaling.

92 evidence implicates disruptions of striatal dopaminergic indices in suicide and major depression.

93 docrine dopamine cells may contribute to the dopaminergic inhibition of prolactin secretion diurnally

94 We discuss the dopaminergic innervation within the individual projectio

95 anglia regions that receive sparse or no VTA dopaminergic innervation, including the dorsal striatum

96 primate orbitofrontal cortex (OFC) receives dopaminergic input from midbrain nuclei, but the role of

97 e substantia nigra (SN) provides the largest dopaminergic input to the brain, projects to the striatu

98 Dopaminergic input to the prefrontal cortex (PFC) increa

99 e-reward associations.SIGNIFICANCE STATEMENT Dopaminergic inputs from ventral tegmental area (VTA) to

100 Cholinergic regulation of dopaminergic inputs into the striatum is critical for no

101 ns; however, it is currently unknown whether dopaminergic inputs to prefrontal cortex (PFC) play simi

102 ey may exhibit similar patterns of activity, dopaminergic inputs to striatum and PFC can elicit diver

103 t-mortem tissue, and histological markers of dopaminergic integrity.

104 etwork-level mechanisms for this cholinergic-dopaminergic interplay.

105 crine cell markers, suggesting that they are dopaminergic ipRGCs.

106 ine unit led to balanced or G protein-biased dopaminergic ligands depending on the stereochemistry of

107 A dopaminergic marker (TH), serotonin (5-HT) or GABA do no

108 ecent advances in the generation of midbrain dopaminergic (mDA) neurons from stem cells for Parkinson

109 turbed dopamine in healthy individuals using dopaminergic medication and asked them to predict variab

110 In contrast to previous studies, however, dopaminergic medication during learning and testing did

111 but they too failed to reproduce effects of dopaminergic medication on reinforcement learning.

112 trodes, for an average of 7.5 hours in 'off' dopaminergic medication state.

113 show enhanced reinforcing effects of chronic dopaminergic medication, and a potential role for indivi

114 Parkinson's disease and can be suppressed by dopaminergic medication, with the degree of suppression

115 rticipants were scanned while on their usual dopaminergic medication.

116 Dopaminergic medications used in the treatment of patien

117 e behaviours reflect the interactions of the dopaminergic medications with the individual's susceptib

118 However, clinical studies of dopaminergic medications, including the DA partial agoni

119 The striatum is a central part of the dopaminergic mesolimbic system and contributes both to t

120 t in overlapping, but spatially dissociable, dopaminergic midbrain regions expressing both types of P

121 and in reactivity to reward feedback in the dopaminergic midbrain-predicted reward-elicited variance

122 analysis of the same data set revealed that dopaminergic modulation activates several additional ana

123 Dopaminergic modulation from the A11 nucleus of the hypo

124 human speech that is due to left-lateralized dopaminergic modulation of brain activity and functional

125 Dopaminergic modulation of prefrontal cortex (PFC) is th

126 Dopaminergic modulation of spinal cord plasticity has lo

127 lse ratio of inputs to the EP suggested that dopaminergic modulation of striatal inputs is mediated b

128 elopment, in particular regionally selective dopaminergic modulation, and the potential of genetic fa

129 Our data indicate that alpha-SYN, present in dopaminergic nerve terminals supplying the subependymal

130 gene, and in a p62-knock-down (p62 KD) human dopaminergic neuroblastoma cell line (SH-SY5Y).

131 The lack of Parkin promoted earlier onset of dopaminergic neurodegeneration and motor defects in the

132 ion have been implicated in substantia nigra dopaminergic neurodegeneration in Parkinson's disease (P

133 ne metabolism abnormalities, and no signs of dopaminergic neurodegeneration.

134 on against cell loss in a zebrafish model of dopaminergic neurodegeneration.

135 BON synapses receive a direct synapse from a dopaminergic neuron (DAN).

136 activity is one of the major hypotheses for dopaminergic neuron death in Parkinson's disease.

137 the mitochondrial complex I, does not cause dopaminergic neuron death or motor impairment.

138 ls, suggesting a role for ErbB4 signaling in dopaminergic neuron function.

139 ization requires odor-evoked activity in the dopaminergic neuron innervating this compartment.

140 ent synaptic disruption, occur in absence of dopaminergic neuron loss in PD.

141 In vivo dopaminergic neuron reprogramming by EMF stimulation of

142 ractors also modified hLRRK2(I2020T) induced dopaminergic neuronal loss in the fly brain and uncovere

143 chondrial dysfunction associates with nigral dopaminergic neuronal loss.

144 tory reaction and degeneration of the nigral-dopaminergic neuronal system exacerbates motor deficit.

145 differentiation of neuronal precursors into dopaminergic neurons (Engrailed 1) and for the oligodend

146 tau in maintaining the survival of midbrain dopaminergic neurons (mDANs) during aging.

147 priate connections for cell therapy.Midbrain dopaminergic neurons (mDAs) in the VTA and SNpc project

148 e in which Ndufs4 was selectively deleted in dopaminergic neurons (Ndufs4 cKO).

149 is effect is triggered by a specific pair of dopaminergic neurons afferent to the mushroom bodies, vi

150 Finally, we find that JH acts through dopaminergic neurons and conclude that an ETH-JH-dopamin

151 lar and anatomical heterogeneity of midbrain dopaminergic neurons and contribute to a better understa

152 evoked abnormal plasticity in nigrostriatal dopaminergic neurons and DMS D1-neurons, contributing to

153 DAT delivery to the presynaptic terminals of dopaminergic neurons and restored sleep to normal length

154 lpha-synuclein pathology, persistent loss of dopaminergic neurons and striatal neurotransmitters, and

155 ncluding the mechanosensory TRP-4 channel in dopaminergic neurons and the D2-like dopamine receptor D

156 Midbrain dopaminergic neurons are highly heterogeneous.

157 tion.SIGNIFICANCE STATEMENT Substantia nigra dopaminergic neurons can be divided into two populations

158 mHTTx1) modulates the expression of IL-34 in dopaminergic neurons derived from a human embryonic stem

159 Here we studied dopaminergic neurons derived from patients with idiopath

160 ity between mushroom body output neurons and dopaminergic neurons enables memory re-evaluation driven

161 Here we report that NCEH-1 protects dopaminergic neurons from alpha-synuclein-dependent neur

162 l redox status and membrane potential of SNc dopaminergic neurons from Sirt3 knockouts.

163 ronal morphology and firing rate showed that dopaminergic neurons function as a coupled oscillator wh

164 n of GDNF in the CNS affects the function of dopaminergic neurons has remained unknown.

165 at CIB1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson's dis

166 gene enhances MPTP-induced neurotoxicity in dopaminergic neurons in CIB1(-/-) mice.

167 hrough DAT in heterologous cells and primary dopaminergic neurons in culture.

168 tier and calbindin-negative ventral tier SNc dopaminergic neurons in mice comprise functionally disti

169 loss of substantia nigra pars compacta (SNc) dopaminergic neurons in Parkinson's disease (PD).

170 , accompanied by progressive degeneration of dopaminergic neurons in SN, neuritic swelling, reduced s

171 stem to decipher the roles of two classes of dopaminergic neurons in the mouse nucleus accumbens in a

172 this, RGMa induced selective degeneration of dopaminergic neurons in the substantia nigra (SN) and af

173 son's disease (PD) is defined by the loss of dopaminergic neurons in the substantia nigra and the for

174 Progressive degeneration of dopaminergic neurons in the substantia nigra pars compac

175 terized by slow, progressive degeneration of dopaminergic neurons in the substantia nigra.

176 motor symptoms due to the selective loss of dopaminergic neurons in the substantia nigra.

177 ecific marker for a novel subset of midbrain dopaminergic neurons in the ventral midbrain that projec

178 (CB1Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral tegmental area (VTA)

179 u haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and r

180 Thus, PPN-evoked burst spiking of SNc dopaminergic neurons in vivo may not only be extrinsical

181 fic dysregulation, exacerbates disruption of dopaminergic neurons in vivo, resulting in the neurodege

182 fects on the survival and function of nigral dopaminergic neurons in which the chronic expression of

183 This pathway recruits negatively reinforcing dopaminergic neurons innervating the same compartment an

184 king in substantia nigra pars compacta (SNc) dopaminergic neurons is a key signaling event in the cir

185 ation of human pluripotent stem cell-derived dopaminergic neurons is a promising approach to treating

186 These results suggest that CB2Rs in dopaminergic neurons may play important roles in the mod

187 riments demonstrate that Neurod6(+) midbrain dopaminergic neurons neurons project to two distinct sep

188 studies reporting mtDNA depletion in nigral dopaminergic neurons of PD patients.

189 as via the projections from reward-sensitive dopaminergic neurons of the midbrain ventral tegmental a

190 rable in Parkinson's disease (PD), including dopaminergic neurons of the substantia nigra (SN) and ch

191 us deep brain stimulation (STN DBS) protects dopaminergic neurons of the substantia nigra pars compac

192 d is associated with the progressive loss of dopaminergic neurons over the course of aging.

193 , RNAi-mediated depletion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrin

194 Midbrain dopaminergic neurons project via the nigrostriatal pathw

195 Stereological counts of nigral dopaminergic neurons revealed a significantly greater ce

196 Reconstructions of sampled AIS of dopaminergic neurons revealed variable lengths (12-60 mu

197 oom body, which drive negatively reinforcing dopaminergic neurons that innervate neighbouring zones.

198 rtment and re-engages positively reinforcing dopaminergic neurons to reconsolidate the original rewar

199 vidence that glutamatergic transmission onto dopaminergic neurons underlies incentive motivation, a w

200 in mouse, we targeted RGMa to adult midbrain dopaminergic neurons using adeno-associated viral vector

201 ex I activity in all cells or selectively in dopaminergic neurons via conditional deletion of the Ndu

202 The degeneration of dopaminergic neurons was accompanied by a strong microgl

203 at mutant primary cortical and mesencephalic dopaminergic neurons were more susceptible to rotenone-i

204 cases of synaptic innervation of the AIS of dopaminergic neurons were observed.

205 D) is characterized by a progressive loss of dopaminergic neurons with limited treatment options.

206 s occurred selectively in calbindin-negative dopaminergic neurons within the SNc.

207 kin mutant phenotypes, in particular loss of dopaminergic neurons, mitochondrial network structure, r

208 e somatodendritic domain of adult male mouse dopaminergic neurons, previously recorded in vivo We obs

209 nction, plasticity, and survival of midbrain dopaminergic neurons, the dysfunction of which contribut

210 red branch-specific plastic changes in these dopaminergic neurons, thus enabling sustained protein co

211 ring of substantia nigra pars compacta (SNc) dopaminergic neurons, we identified and characterized th

212 acetylation, decreased MnSOD activity in SNc dopaminergic neurons, whereas mutagenesis of lysine 68 t

213 ted into reduced microglial toxicity towards dopaminergic neurons.

214 of PPN axons reliably evoked spiking in SNc dopaminergic neurons.

215 in which the mitochondrial DNA is damaged in dopaminergic neurons.

216 network and distinct subsets of reinforcing dopaminergic neurons.

217 tDNA) undergoes double-strand breaks only in dopaminergic neurons.

218 n-G (Ank-G) was used to visualize the AIS of dopaminergic neurons.

219 s, and induced pluripotent stem cell-derived dopaminergic neurons.

220 mice led to a clear age-related loss of SNc dopaminergic neurons.

221 ene function in specific subsets of midbrain dopaminergic neurons.

222 TA), subsequently increasing SP release onto dopaminergic neurons.

223 ns in TRP-4 reduce the mechanosensitivity of dopaminergic neurons.

224 maintenance of mitochondrial homeostasis in dopaminergic neurons.

225 he membrane potential of mitochondria in SNc dopaminergic neurons.

226 coupling it results in a greater loss of SNc dopaminergic neurons.

227 on of the UPR(MT) synergistically potentiate dopaminergic neurotoxicity.

228 Because of the evolutionary conservation in dopaminergic neurotransmission between Drosophila and pe

229 with Se-induced oxidative stress and altered dopaminergic neurotransmission in the brain.

230 kers and the expression of genes involved in dopaminergic neurotransmission in the zebrafish brain.

231 thology, synaptic disruption, dysfunction of dopaminergic neurotransmission, motor impairment, and me

232 e for the protein alpha-synuclein present in dopaminergic nigral afferents in the regulation of adult

233 Here, we report that alpha-SYN present in dopaminergic nigral afferents is essential for the norma

234 processes in general and how it affects the dopaminergic nigrostriatal pathway, in particular.

235 ning" (RL) have repeatedly been found within dopaminergic nuclei of the midbrain and dopaminoceptive

236 groups were detected and, in particular, the dopaminergic nucleus of the periventricular organ was ev

237 2 neuronal subtypes producing glutamatergic, dopaminergic or GABAergic markers for synaptic neurotran

238 ms for brain region-dependent alterations in dopaminergic parameters.

239 Rodent studies have suggested that dopaminergic pathway projecting to the medial prefrontal

240 sessment of the integrity of the presynaptic dopaminergic pathway.

241 In TH::Cre rats, the dopaminergic pathways from the ventral tegmental area to

242 nt stimulus features are learned in parallel dopaminergic pathways, with formation of an integrated u

243 segregation of nigrostriatal and mesolimbic dopaminergic pathways.

244 Here, we sought to investigate the effect of dopaminergic perturbations on adaptive prediction error

245 of the influence of a genetic biomarker, the dopaminergic polymorphism DRD2 C957T.

246 Most models of RL assume that the dopaminergic prediction error signal drives plasticity i

247 (2017) identify specific markers of midbrain dopaminergic progenitors to improve their derivation and

248 itional source of neurotransmitter acting on dopaminergic receptors in the hippocampus.

249 HIV-LMX1A-AA carriers who might have greater dopaminergic reserve.

250 We found that the dopaminergic reward circuitry of zebra finches can simul

251 tal area (VTA), the origin of the mesolimbic dopaminergic reward system.

252 w that these other players interact with the dopaminergic RL system, interfering with its key computa

253 he model predicts that the interplay between dopaminergic signal and cortical activity contributes to

254 ircuits and strengthen the general idea that dopaminergic signaling amplifies the effects of reward e

255 Here we asked whether dopaminergic signaling supports a TD learning framework

256 llular respiration, serves as a modulator of dopaminergic signaling, and its presence can indicate th

257 trate phenotypes consistent with exaggerated dopaminergic signaling, including alterations in dopamin

258 dopamine neurons plays a fundamental role in dopaminergic signaling.

259 rd learning, putatively reflecting decreased dopaminergic signaling.

260 We hypothesize that dopaminergic signalling contributes to differential cuta

261 Dopaminergic signalling is established as playing an imp

262 nism of sensory modulation through cutaneous dopaminergic signalling.

263 s by which EAAC1 can shape glutamatergic and dopaminergic signals and control repeated movement execu

264 er colocalization was observed in male mouse dopaminergic somatodendritic and terminal regions.

265 Our work demonstrates that dopaminergic spinal projections are necessary for the ma

266 racteristics of beta bursts are dependent on dopaminergic state.

267 those involved in the upstream regulation of dopaminergic synthesis, through glutamatergic and gamma-

268 The dopaminergic system emanating from the ventral tegmental

269 contributed to the theory of a desensitized dopaminergic system in bulimia nervosa.

270 vidence in support for a similar role of the dopaminergic system in humans is emerging from fMRI data

271 uggest that asymmetrical degeneration of the dopaminergic system induces an increased drive from the

272 our work provides new insights into how the dopaminergic system interacts with spinal circuits to pr

273 oid receptors, which modulate the mesolimbic dopaminergic system, and provides a neurobiological basi

274 been used to examine multiple aspects of the dopaminergic system.

275 AR1 has been indicated as a modulator of the dopaminergic system.

276 elopment and maintenance of the mesostriatal dopaminergic system.

277 demonstrate that enhancing noradrenergic and dopaminergic systems does not systematically improve vis

278 cerebello-rubro-spinal, and hypothalamic A11 dopaminergic systems in the development of restless legs

279 owed a significant effect on cholinergic and dopaminergic systems.

280 chemical changes in the dopaminergic and non-dopaminergic systems.

281 ressive forelimb asymmetry, loss of striatal dopaminergic terminal density and modest loss of SNpc do

282 Our results showed selective degeneration of dopaminergic terminals throughout the striatum in indivi

283 regulated activity of ventral tegmental area dopaminergic (TH(VTA)) neurons, as well as from more glo

284 The influence of dopaminergic therapy on EDS is dose dependent.

285 Dopaminergic therapy was associated with EDS at years 2

286 was no association with the dose or class of dopaminergic therapy.

287 triatal circuitry that vary as a function of dopaminergic tone and may have relevance to aspects of t

288 n tobacco smokers, suggesting an increase in dopaminergic tone.

289 tudies have shown that resveratrol regulates dopaminergic transmission and behavioral effects of drug

290 macological challenge designed to facilitate dopaminergic transmission can enhance striatal responses

291 ypotheses put forth regarding alterations in dopaminergic transmission in this disease, molecular ima

292 To investigate the effects of increased dopaminergic transmission on reward-related striatal fun

293 Acute enhancement of dopaminergic transmission potentiated reward-related str

294 by Queen Square Brain Bank criteria, were on dopaminergic treatment with wearing-off effects, and wer

295 iate the reinforcing effects of cocaine, the dopaminergic variations underlying individual difference

296 signals arising from excitatory habenula and dopaminergic ventral tegmentum inputs, which activate an

297 Rather, dopaminergic VTA-PFC activity can control whether mice m

298 Neither phasic nor tonic stimulation of dopaminergic VTA-PFC projections elicited place preferen

299 In summary, despite the fact that dopaminergic VTA-PFC projections exhibit phasic increase

300 the caudal midbrain that correlate with high dopaminergic yield after transplantation in vivo.