ライフサイエンスコーパス: dorsal mesoderm

1 ecifically affected neurogenesis but not the dorsal mesoderm.

2 ting that oep acts downstream of inducers of dorsal mesoderm.

3 signaling pathway than the induction of the dorsal mesoderm.

4 gland can be induced by neural plate and by dorsal mesoderm.

5 eta-catenin-deficient marginal zones to form dorsal mesoderm.

6 quired for formation of the neural plate and dorsal mesoderm.

7 ocious mediolateral intercalation of caudal, dorsal mesoderm.

8 and can account for extension throughout the dorsal mesoderm.

9 mal cap explant assays and in the endogenous dorsal mesoderm.

10 definitive amnioserosa, dorsal ectoderm and dorsal mesoderm.

11 to prevent ectopic enhancer activity in the dorsal mesoderm.

12 even-skipped (eve) to a small region of the dorsal mesoderm.

13 ensive AP brain patterning in the absence of dorsal mesoderm.

14 ultiple anteroposterior locations within the dorsal mesoderm.

15 n, as well as cell autonomous suppression of dorsal mesoderm.

16 nsduces activin/TGF-beta signals, generating dorsal mesoderm.

17 ndicating an early role for FGF signaling in dorsal mesoderm.

18 xtension movements normally undergone by the dorsal mesoderm.

19 , activated by activin-like ligands, induces dorsal mesoderm.

20 cally in the YSL induces expanded or ectopic dorsal mesoderm.

21 s directed extension in cultured explants of dorsal mesoderm.

22 ative differences in their ability to induce dorsal mesoderm.

23 in response to inductive signals from normal dorsal mesoderm.

24 d that the expression of NckK229 ventralized dorsal mesoderm.

25 like, like loss of wnt8, causes expansion of dorsal mesoderm, (4) sp5-like knockdown reduces the defe

26 that boz and sqt act in parallel to specify dorsal mesoderm and anterior neuroectoderm.

27 g sites and is responsible for repression in dorsal mesoderm and ectoderm at mid-gastrula stages.

28 tions of activin above those known to induce dorsal mesoderm and heart, in an FGF-independent manner.

29 events, inhibits convergent extension in the dorsal mesoderm and in the posterior neural ectoderm.

30 elevated C-cadherin adhesion activity in the dorsal mesoderm and interferes with the normal blastopor

31 that is required for the development of the dorsal mesoderm and its derivatives in the Drosophila em

32 yos, BMP-11 acts more like activin, inducing dorsal mesoderm and neural tissue, and less like other f

33 bm can regulate convergent extension in both dorsal mesoderm and neural tissue.

34 embryonic explants consisting of presumptive dorsal mesoderm and neurectoderm (Keller explants), and

35 Xenopus, convergent extension occurs in the dorsal mesoderm and posterior neural ectoderm, and is me

36 at the GATA gene pannier is expressed in the dorsal mesoderm and required for cardial cell formation

37 bers of the TGFbeta Nodal subfamily, pattern dorsal mesoderm and the embryonic axes.

38 ive in the early mesoderm, the second in the dorsal mesoderm and the third in cardioblasts.

39 is a wave of Xombi expression, beginning in dorsal mesoderm and then extending to lateral and ventra

40 t uniquely, as specification tests show that dorsal mesoderm arises in fragments of the embryo which

41 Arg is expressed in the dorsal mesoderm at the onset of gastrulation, and both g

42 Suppression of dorsal mesoderm by Hex is accompanied by the down-regula

43 of Goosecoid and Chordin, while induction of dorsal mesoderm by Hex-(lambda)VP2 results in activation

44 sing fluorescent fusion proteins that during dorsal mesoderm C&E, the noncanonical Wnt component Pric

45 We also demonstrate that the dorsal mesoderm can be induced independently of signals

46 gnals regulate the polarity of intercalating dorsal mesoderm cells during convergent extension.

47 qt function to induce high levels of ectopic dorsal mesoderm, consistent with sqt acting either downs

48 regulator of the Nodal pathway in zebrafish dorsal mesoderm development and establish a broadly cons

49 A transcription factor pannier acts early in dorsal mesoderm development to promote the development o

50 indicated that boz and sqt are required for dorsal mesoderm development.

51 the broad phase 2 expression pattern in the dorsal mesoderm does not restrict to the constrained pha

52 Cell division is also absent in involuting dorsal mesoderm during gastrulation in Xenopus, and to a

53 During Xenopus gastrulation, the dorsal mesoderm exhibits two different cell behaviors in

54 n of eng2, normally restricted to first arch dorsal mesoderm, expands ventrally in hand2 and edn1 mut

55 rm identity requires continual repression of dorsal mesoderm factors, including repressors of ventral

56 scriptional regulator Foxd3 is essential for dorsal mesoderm formation in zebrafish, and that this fu

57 Second, a gene associated with dorsal mesoderm formation, brachyury, is expressed norma

58 g growth factor-beta superfamily that induce dorsal mesoderm formation.

59 organizer and this function is essential for dorsal mesoderm formation.

60 ructures by suppressing signals that promote dorsal mesoderm formation.

61 we show GSK-3 is also required for zebrafish dorsal mesoderm formation.

62 hila tinman gene, which is essential for the dorsal mesoderm formation.

63 Madr2 induces dorsal mesoderm from Xenopus ectoderm and can mimic the

64 As a consequence of the suppression of dorsal mesoderm gene expression, bone morphogenetic fact

65 n: lower levels of Smad7 block activation of dorsal mesoderm genes and higher levels block all mesode

66 ain occur normally in wnt8; swr mutants, but dorsal mesoderm genes eventually come to be expressed th

67 in specification and differentiation of the dorsal mesoderm have been studied, the role of these gen

68 ich patterns the ectoderm such that it forms dorsal mesoderm in response to ventral inductive signals

69 The dorsal mesoderm in the frog Hymenochirus forms by a mech

70 endodermal development and the induction of dorsal mesoderm in vivo.

71 al and lung cancer, has been shown to induce dorsal mesoderm in Xenopus laevis in response to transfo

72 tical roles in the formation of endoderm and dorsal mesoderm in zebrafish.

73 s required for development of the Drosophila dorsal mesoderm, including heart.

74 protein processing controls production of a dorsal mesoderm inducer in these two species.

75 aps results in the conversion of Xnr2 from a dorsal mesoderm inducer to a ventral mesoderm inducer, s

76 In Xenopus the activins and Vg1 are potent dorsal mesoderm inducers while members of the bone morph

77 beta family members, such as Vg1, are potent dorsal mesoderm inducers, the TGF-beta pathway only weak

78 the dorsal yolk syncytial layer, a source of dorsal mesoderm inducing signals, and mutational analysi

79 tralising signals from ALK-2* antagonise the dorsal mesoderm-inducing signal derived from ALK-4*, sug

80 f the early VegT- and beta-catenin-regulated dorsal-mesoderm-inducing gene Xnr5.

81 nvergent extension movements associated with dorsal mesoderm induction and the expression of goosecoi

82 Dorsal mesoderm induction in arthropods and ventral meso

83 Dorsal mesoderm is itself subdivided into posterior and

84 ochord domain is specified in the vertebrate dorsal mesoderm, it undergoes dramatic morphogenesis.

85 xplants of deep neural plate with underlying dorsal mesoderm, lateral neural plate cells show a monop

86 nal for BMP2 and BMP4, whereas Xmad2 induces dorsal mesoderm like Vg1, activin, and nodal.

87 Loss of the dorsal mesoderm lineages is due to a high incidence of a

88 retarded by 8.5 d.p.c. and they fail to form dorsal mesoderm lineages, including chordamesoderm and p

89 In Xenopus, Smad2 can induce dorsal mesoderm, mimicking Vg-1, activin and nodal.

90 and somatic muscle progenitors in the early dorsal mesoderm of Drosophila.

91 ulate the gonad after transplantation to the dorsal mesoderm of host embryos following germ-band exte

92 play spatial regulation and are found in the dorsal mesoderm of the organizer.

93 al determinant, ladybird, is absent from the dorsal mesoderm of Tribolium embryos.

94 ession when the ectoderm was recombined with dorsal mesoderm or treated with fibroblast growth factor

95 le that can directly induce ectoderm to form dorsal mesoderm, or a member of the Wnt family, which pa

96 NS) is induced by signals emanating from the dorsal mesoderm, or organizer, that divert the ectoderm

97 lation of organizer signaling might regulate dorsal mesoderm patterning and axial morphogenesis.

98 ntagonist Chordin and other signals from the dorsal mesoderm play important roles in this process.

99 a embryo, cardioblasts emerge from bilateral dorsal mesoderm primordia, followed by alignment as rows

100 d2 mRNA also synergized to induce ventral or dorsal mesoderm, respectively.

101 The subsequent dorsal mesoderm-restricted mef2 expression is mediated t

102 neural plate explants lacking the underlying dorsal mesoderm show a bipolar, mediolaterally directed

103 on, followed by restricted expression in the dorsal mesoderm, specific expression in muscle progenito

104 U 2 suppresses the expression of a number of dorsal mesoderm-specific genes, including gsc, Xlim-1, X

105 This frizzled -mediated wnt pathway for dorsal mesoderm specification provides the first evidenc

106 t only pyr mutants exhibit severe defects in dorsal mesoderm specification.

107 Drosophila tinman, which is required for the dorsal mesoderm specification.

108 led function is necessary and sufficient for dorsal mesoderm specification.

109 re induced within the segmental areas of the dorsal mesoderm that receive intersecting Dpp and Wg inp

110 ent of most cell types deriving from the non-dorsal mesoderm - the fat body, somatic cells of the gon

111 rom Xenopus embryos induced both ventral and dorsal mesoderm, thereby mimicking the effects of TGF-be

112 formation in the whole embryo and transforms dorsal mesoderm to a ventral fate.

113 erminant(s) functions as a direct inducer of dorsal mesoderm (Vg1-like) or whether it acts to pattern

114 en the development and cell behaviors of the dorsal mesoderm, we have examined these behaviors in dis

115 the homeobox gene tinman is expressed in the dorsal mesoderm where it functions in the specification

116 ate in spt mutants almost exclusive from the dorsal mesoderm whereas, pronephros and tail originate f

117 entifies one specific subset of cells in the dorsal mesoderm, which give rise to particular pericardi

118 Signals from a region of dorsal mesoderm, which is termed the organizer, pattern