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2 spinal cord slice preparation with attached dorsal roots also demonstrated that CFA inflammation red
3 the sympathetic trunk or Remak fibers of the dorsal roots, although, in those structures, they wrappe
5 Expressed in somatosensory neurons of the dorsal root and trigeminal ganglion, the transient recep
9 ote recovery of sensorimotor functions after dorsal root avulsion, and that these effects are mediate
10 gdorferi antigen was detected in the DRG and dorsal roots by immunofluorescence staining and confocal
11 la zoster virus (VZV) establishes latency in dorsal root, cranial nerve, and enteric ganglia and can
12 regeneration in adult rat spinal cord after dorsal root crush and adeno-associated virus transgene e
13 f sensory axons into the spinal cord after a dorsal root crush as well as substantial axon regrowth i
16 ed its efficacy in enhancing regeneration of dorsal root (DR) axons, whose regenerative capacity is p
17 ion channel that is expressed in a subset of dorsal root (DRG) and trigeminal ganglia sensory neurons
18 glia regenerated through the tenascin-C-rich dorsal root entry zone into the dorsal column up to C1 l
22 mal and distal peripheral nerve segments and dorsal roots from mice and pigtail monkeys (Macaca nemes
23 e protease inhibitor, was upregulated in the dorsal root ganglia (DRG) after nerve injury, which was
24 cleared from plasma but all persisted in the dorsal root ganglia (DRG) and sciatic nerve (SN) for up
25 hese effects correlated with degeneration in dorsal root ganglia (DRG) and sciatic nerve and abundanc
28 g the C133W SPT mutant, we found that mutant dorsal root ganglia (DRG) during growth in vitro exhibit
29 ransducing peripheral sensory neurons of the dorsal root ganglia (DRG) express kainate receptors (KAR
30 N-nitrosourea (ENU)-induced mutation affects dorsal root ganglia (DRG) formation in ouchless mutant z
31 he cell bodies of primary nociceptors within dorsal root ganglia (DRG) has been found to make major c
32 mber of TRPV1(+) neurons is increased in the dorsal root ganglia (DRG) in paclitaxel-treated rats and
33 spartate receptors (NMDARs) expressed in the dorsal root ganglia (DRG) in the inflammatory sensitizat
34 ed in primary afferent neurons isolated from dorsal root ganglia (DRG) innervating the lower gastroin
38 itro and in patch-clamp electrophysiology in dorsal root ganglia (DRG) neurons and hippocampal slices
39 ECE-1 are expressed and colocalize in murine dorsal root ganglia (DRG) neurons and human skin nerves.
40 h lipid kinases generate PIP2 in nociceptive dorsal root ganglia (DRG) neurons and if these kinases r
41 Using recombinant systems, mouse-cultured dorsal root ganglia (DRG) neurons and in vivo experiment
42 acutely dissociated small diameter (<27 mum) dorsal root ganglia (DRG) neurons and on miniature (m)EP
43 rvous system revealed that Schwann cells and dorsal root ganglia (DRG) neurons developed abnormally i
45 axons.SIGNIFICANCE STATEMENT Small-diameter dorsal root ganglia (DRG) neurons mediating nociception
47 nels were examined in guinea-pig dissociated dorsal root ganglia (DRG) neurons using calcium imaging
48 performed on isolated naive and injured rat dorsal root ganglia (DRG) neurons, and the analgesic eff
49 hyperexcitability and spontaneous firing of dorsal root ganglia (DRG) neurons, whole-cell patch clam
53 rtantly, the trivalent vaccine protected the dorsal root ganglia (DRG) of 32/33 (97%) mice between da
54 e central nervous system, spinal nerves, and dorsal root ganglia (DRG) of rhesus macaques that were i
55 n with rAAV8 would result in transduction of dorsal root ganglia (DRG) or trigeminal ganglia (TG), re
56 verning the maintenance and proliferation of dorsal root ganglia (DRG) progenitors are largely unknow
59 used the up-regulation of Ran and RanGAP1 in dorsal root ganglia (DRG) under basal conditions and dur
62 from the sciatic nerve (SN), the lumbar 4/5 dorsal root ganglia (DRG), and the trigeminal ganglia (T
64 g COX-2, EP2, EP4) in endometriosis lesions, dorsal root ganglia (DRG), spinal cord, thalamus and for
65 urons, including some sensory neurons of the dorsal root ganglia (DRG), suggesting an extranuclear ro
66 spinal afferents is well known to reside in dorsal root ganglia (DRG), the morphology and location o
67 nt increased the number of T cells in lumbar dorsal root ganglia (DRG), where CD8(+) T cells were the
72 with neuropathic and/or inflammatory pain in dorsal root ganglia (DRGs) and spinal cord both during t
73 tes nerve injury and inflammatory markers in dorsal root ganglia (DRGs) and spinal cord up to 2 wk af
75 , starting with gene expression profiling of dorsal root ganglia (DRGs) combined with multi-level bio
76 Rapidly adapting (RA) mechanoreceptors in dorsal root ganglia (DRGs) express Ret and the co-recept
77 d range of optical stimulation parameters on dorsal root ganglia (DRGs) expressing channelrhodopsin 2
78 and sensitization responses to capsaicin in dorsal root ganglia (DRGs) following application of supe
79 ty on the regeneration of different types of dorsal root ganglia (DRGs) neurons after sciatic nerve i
80 -EpOME (9,10-epoxy-12Z-octadecenoic acid) in dorsal root ganglia (DRGs) of paclitaxel-treated mice as
81 pes, and its gene expression is increased in dorsal root ganglia (DRGs) of paclitaxel-treated rats.
84 e surgical procedure for extraction of human dorsal root ganglia (hDRG) and the necessary modificatio
85 from the 4th lumbar (L4) and 5th lumbar (L5) dorsal root ganglia after L5 spinal nerve ligation (SNL)
88 show that memory CD4 T cells migrate to the dorsal root ganglia and spinal cord in response to infec
89 inhibit mammalian NaV channels expressed in dorsal root ganglia at concentrations up to 100 microM.
90 the vagina and reduced latent viral loads in dorsal root ganglia but induced lower serum neutralizing
91 ta opioid receptor-Ca(2+)channel coupling in dorsal root ganglia desensitized by ARM390 and the rate
98 een functional subtypes of sensory neuron in dorsal root ganglia is distorted by Gars mutations, lead
100 NP)]Ts1, we were able to optically stimulate dorsal root ganglia neurons and generate action potentia
101 model as well as in vitro effects of HOCl on dorsal root ganglia neurons and mouse bone marrow-derive
103 that in small-diameter, capsaicin-sensitive dorsal root ganglia neurons corresponding to nociceptors
104 impaired response to several pruritogens in dorsal root ganglia neurons excised from NC/Nga mice aft
108 Transcriptional profiling of IL-31-activated dorsal root ganglia neurons revealed enrichment for gene
109 , the growth cones of primary small-diameter dorsal root ganglia neurons showed abundant IL-31 recept
110 detected both KCNQ2 and KCNQ3 in a subset of dorsal root ganglia neurons that correspond to D-hair Ad
111 s; (iii) suppresses proinflammatory state of dorsal root ganglia neurons to decrease pelvic pain; (iv
112 els, we determined that the treatment of rat dorsal root ganglia neurons with E2 increased mRNA conce
113 d sensory neurons, which account for >40% of dorsal root ganglia neurons, display resistance to rabie
114 previous reports of ASIC3 mRNA expression in dorsal root ganglia neurons, we found that the ASIC3 ant
120 10 transduces neurons in the spinal cord and dorsal root ganglia of immunodeficient mice with higher
123 ncreased activity of the Epac target Rap1 in dorsal root ganglia of WT, but not of Epac1(-/-), mice.
124 gated Na(+), K(+) and Ca(2+) channels in rat dorsal root ganglia or VGSC forms individually expressed
126 ochemistry was used to detect TRPV4 in human dorsal root ganglia samples (from the National Disease R
127 NCSC-derived human Schwann cells with rodent dorsal root ganglia showed interaction of the Schwann ce
128 ession G-protein-coupled receptors in murine dorsal root ganglia showed that both receptors were amon
129 f thrombospondin-4 (TSP4) in spinal cord and dorsal root ganglia that contributes to neuropathic pain
134 anscription factor to sensory neurons of the dorsal root ganglia using a gene therapy approach and fo
135 from SNE-injured and contralateral L4 and L5 dorsal root ganglia were cultured in a compartmentalized
137 r treatment alone when dissociated embryonic dorsal root ganglia were seeded onto inhibitory substrat
139 ecapitulates the selective death of sensory (dorsal root ganglia) and autonomic neurons observed in F
141 muscle cells, and neurons in trigeminal and dorsal root ganglia, as detected by light and electron m
142 bpopulation of neurons in the trigeminal and dorsal root ganglia, but was absent in sympathetic neuro
143 ll lines and in nociceptive neurons of mouse dorsal root ganglia, Cat-S and a decapeptide mimicking t
145 neuronal and non-neuronal tissues, including dorsal root ganglia, spinal cord, and keratinocytes.
146 Despite on-target activity in small-diameter dorsal root ganglia, spinal slices, and in a mouse model
147 97%) animals had no evidence of infection of dorsal root ganglia, suggesting that the vaccine may pre
162 hat CXCL12 and CXCR4 were upregulated in the dorsal root ganglion (DRG) after chronic compression of
163 injury causes down-regulation of MORs in the dorsal root ganglion (DRG) and diminishes the opioid eff
164 titutive autophagosome biogenesis in primary dorsal root ganglion (DRG) and hippocampal cultures.
165 KChIP2, KChIP3, DPP6, and DPP10 in adult rat dorsal root ganglion (DRG) and spinal cord by immunohist
166 ncreases in osmolality excite isolated mouse dorsal root ganglion (DRG) and trigeminal ganglion (TG)
168 port that stimulated membrane enlargement in dorsal root ganglion (DRG) axons is triggered by intra-a
169 tigate mRNA expression in colonic tissue and dorsal root ganglion (DRG) cells isolated from 3- and 24
170 at a dose of 100 mpk PO due to insufficient dorsal root ganglion (DRG) exposure attributed to poor m
171 pression and functional role of Panx1 in the dorsal root ganglion (DRG) in the development of chronic
172 ion of HIV infection and is characterized by dorsal root ganglion (DRG) inflammation and intraepiderm
173 gated potassium channel subunit Kcna2 in the dorsal root ganglion (DRG) is critical for DRG neuronal
174 nsgenic mice lacking Merkel cells had normal dorsal root ganglion (DRG) neuron numbers, but fewer DRG
176 hondrial trafficking plays a central role in dorsal root ganglion (DRG) neuronal cell survival and ne
178 nduced spontaneous pain and axonal injury of dorsal root ganglion (DRG) neurons and inhibited CCI-evo
179 fast-inactivating Kv3.4 potassium current in dorsal root ganglion (DRG) neurons contributes to the hy
180 s axon growth from neurons; adult miR-155 KO dorsal root ganglion (DRG) neurons extend 44% longer neu
181 en implicated in the hyperexcitable state of dorsal root ganglion (DRG) neurons following direct inju
183 GKIalpha) that regulates axon bifurcation of dorsal root ganglion (DRG) neurons in the spinal cord.
184 -expression network analysis, we categorized dorsal root ganglion (DRG) neurons into different subtyp
185 hat the activity of TRPM3 expressed in mouse dorsal root ganglion (DRG) neurons is inhibited by agoni
186 rophysiological characterization of isolated dorsal root ganglion (DRG) neurons revealed that RPRFami
189 Nociceptors are a particular subtype of dorsal root ganglion (DRG) neurons that detect noxious s
190 ciatic nerve allows the central processes of dorsal root ganglion (DRG) neurons to spontaneously rege
191 4-well format axon degeneration assay in rat dorsal root ganglion (DRG) neurons using a trophic facto
192 hat voltage-gated sodium channels (VGSCs) in dorsal root ganglion (DRG) neurons were sensitized in a
194 thereby producing hyperexcitability of small dorsal root ganglion (DRG) neurons, which include nocice
195 ury induces changes in gene transcription in dorsal root ganglion (DRG) neurons, which may contribute
203 with microglia BV-2 cells exposed to G-CSF, dorsal root ganglion (DRG) nociceptors become hyperexcit
204 melanoma and normal neural tissues including dorsal root ganglion (DRG) produce PD-L1 that can potent
205 ort functional expression of SHANK3 in mouse dorsal root ganglion (DRG) sensory neurons and spinal co
209 set of nonpeptidergic nociceptors within the dorsal root ganglion (DRG), and knockdown of Kv4.3 selec
210 reduction in K(+) channel expression in the dorsal root ganglion (DRG), but little is known about th
211 icular pain model, local inflammation of the dorsal root ganglion (DRG), we observed marked increases
212 in nociceptor (pain-sensing) neurons of the dorsal root ganglion (DRG), where they transmit the larg
216 vivo forepaw muscles/median and ulnar nerves/dorsal root ganglion (DRG)/spinal cord (SC) recording pr
217 at the Ascl1 promoter, isolated from murine dorsal root ganglion (hypermethylated) and striated cell
218 ressed in a subset of sensory neurons of the dorsal root ganglion and in cutaneous mechanoreceptors k
222 y of glial cells and reduced spinal cord and dorsal root ganglion cytokine levels without affecting p
225 permeant cAMP analog, 8-bromo cAMP, into the dorsal root ganglion induced mechanical hyperalgesia and
226 imulated oligodendrocytes was validated in a dorsal root ganglion microfluidics chamber platform.
228 adapting, mechanically activated currents in dorsal root ganglion neuronal cultures are absent in Pie
231 , PKCdelta, and PKC was also observed in the dorsal root ganglion neurons after chronic treatment wit
233 ase ion transporter in both cultured primary dorsal root ganglion neurons and injured peripheral nerv
234 f3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR.
235 that in small PLCdelta4(-/-) TRPM8-positive dorsal root ganglion neurons cold, menthol and WS-12, a
236 n; and (5) electrophysiology recordings from dorsal root ganglion neurons collected during remission
237 tion of the alpha2delta-1 subunit in sensory dorsal root ganglion neurons contributes to the generati
239 pic screen, we find that CAST/Ei mouse adult dorsal root ganglion neurons extend axons more on CNS my
242 c or optogenetic depolarization of GABAergic dorsal root ganglion neurons in vivo reduced acute and c
244 K-2 channels was also demonstrated in native dorsal root ganglion neurons indicating that heterodimer
248 teers, sensitized TRPV1 in mouse nociceptive dorsal root ganglion neurons via HRH1; this effect could
249 ratching behavior and activation of cultured dorsal root ganglion neurons was dependent on Mrgprs rat
250 two distinct types of cutaneous nociceptive dorsal root ganglion neurons were identified as respondi
252 n prostate cells, PC3 prostate cancer cells, dorsal root ganglion neurons, and hippocampal neurons.
253 1 x 10(12) vg of AAV-PHP.S transduced 82% of dorsal root ganglion neurons, as well as cardiac and ent
254 age-gated K(+) channel robustly expressed in dorsal root ganglion neurons, becomes dysfunctional upon
255 el, depolarize resting membrane potential of dorsal root ganglion neurons, enhance spontaneous firing
258 ed sustained ASIC currents in both groups of dorsal root ganglion neurons, independent of mu opioid r
260 physiology and Ca(2+) imaging experiments on dorsal root ganglion neurons, NGF- and IL-6-induced incr
261 nic spinal commissural neurons, motoneurons, dorsal root ganglion neurons, retinal ganglion cells, an
262 ppressed spontaneous activity in dissociated dorsal root ganglion neurons, reversed hypersensitivity
263 g calcium imaging in cultured primary murine dorsal root ganglion neurons, the response of neurons af
264 een TLR4 and TRPV1 is shown in rat and human dorsal root ganglion neurons, TLR4/TRPV1-coexpressing HE
266 tion in both male and female embryonic mouse dorsal root ganglion neurons, we show that MAP4K4, MINK1
275 y processes characterized by spinal cord and dorsal root ganglion production of proinflammatory cytok
276 fer elevated intracellular calcium levels in dorsal root ganglion pruriceptors, and (iii) injection o
278 P that binds and regulates multiple mRNAs in dorsal root ganglion sensory neurons and thereby promote
279 ated virus (AAV) has been shown to transduce dorsal root ganglion sensory neurons following direct in
281 ta from an in vitro preparation of small rat dorsal root ganglion somata showing a reduction in the m
282 ore variable across cultures than in primary dorsal root ganglion, particularly for genes related to
283 peripheral immune cell infiltration into the dorsal root ganglion, suggesting that adaptive immune re
287 d there were no differences in viral load at dorsal root ganglionic (DRG) neurons at day 4 postinfect
288 We show here that synaptic contacts from dorsal root ganglions to a small number of dorsal column
289 eripheral nerves, but not proximal nerves or dorsal roots, is resistant to tetrodotoxin and that, in
290 , compound action potentials were made, from dorsal roots isolated from rats with or without complete
291 eys (n = 6) received either a unilateral (1) dorsal root lesion (DRL), (2) or a combined DRL/dorsal c
293 ut; they can generate signals in the form of dorsal root reflexes that are transmitted antidromically
294 nts (EPSCs) of dorsal horn neurons evoked by dorsal root stimulation in spinal cord slices from wild-
295 ral root potentials evoked by long and short dorsal root stimulation lengths, to maximize and minimiz
298 "natural" locomotor output was evoked using dorsal-root stimulation, ouabain increased burst frequen
300 B2 markedly enhances regeneration of damaged dorsal roots, while evoking little change in intact root
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