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1 Most of these initial changes were dose dependent.
2 embrane, and the kinetics of regression were dose dependent.
3 influence of dopaminergic therapy on EDS is dose dependent.
4 c toward many different chemoattractants and dose-dependent.
5 nd immune responses to cAd3-EBO vaccine were dose-dependent.
6 he duration of CP inhibition (2-14 days) was dose-dependent.
7 apy with (211)At-MX35-F(ab')2 was strong and dose-dependent.
8 ects on outflow physiology are location- and dose-dependent.
12 n-albicans species, and it exhibited potent, dose-dependent activity in a mouse model of invasive can
13 effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals w
18 -Abeta40 or BRI-Abeta42 together resulted in dose-dependent and cumulative changes reminiscent of AMD
21 : Pro-inflammatory cytokine production had a dose-dependent and temporal association with penile HIV
27 dministration of ALN-GO1 resulted in potent, dose-dependent, and durable silencing of the mRNA encodi
28 ol clearance in macrophages in constitutive, dose-dependent, and reversible fashion but did not affec
29 hemotherapeutics is limited by irreversible, dose-dependent, and sometimes life-threatening cardiotox
31 0 = 1.8 nM) selective for the periphery with dose-dependent anti-inflammatory activity in acute and c
32 overactive in ccRCC and that MLN4924 induces dose-dependent anti-proliferation, anti-migration, anti-
33 pain and found that acetaminophen exerted a dose-dependent antihyperalgesic action, which was mimick
35 ered in organic solvent (isopropanol) showed dose-dependent antimicrobial activity against the tested
36 to bleach a nucleic acid-binding dye causing dose-dependent apoptosis of individual cells without col
37 ce interval [95% CI], 1.05 to 1.46), but the dose-dependent association across the quartiles was not
38 f a polymorphism of CELF4 (rs1786814) on the dose-dependent association between anthracyclines and ca
40 ncow milk consumption and height.There was a dose-dependent association between higher noncow milk co
45 ek) were not associated with HFpEF risk, and dose-dependent associations with lower HFpEF risk were o
46 d larger vessels (>10 microm), overlain by a dose-dependent astroglial scar-like formation and recrui
49 -HT1BR partial agonist AZ10419369 elicited a dose-dependent biphasic hemodynamic response that was re
51 in treatment showed responses that were drug-dose dependent but unaffected by the H9e hydrogel concen
52 inds PKM2 and inhibits BC cell survival in a dose-dependent but pyruvate kinase activity-independent
54 ompatibility with alveolar Type I cells, and dose-dependent caveolae-mediated in vitro uptake by lung
57 more, we observed that 1B6 displayed a rapid dose-dependent clearance (t(1/2) 10-60 h) in contrast to
58 psychoactive component of cannabis, produced dose-dependent conditioned place aversion and a reductio
60 e donor motifs, we also demonstrate the H2O2 dose-dependent COS/H2S release from each donor core, est
62 reatment of NSCLC cells with CMLD-2 produced dose-dependent cytotoxicity, caused a G1 phase cell-cycl
63 retinal phenotype characterized by time- and dose-dependent declines in rod and cone photoreceptor fu
64 ble peptides that demonstrated a significant dose-dependent decrease in blood glucose in chronic stud
69 erm treatments with compound 8 resulted in a dose-dependent decrease of Notch signaling activity, hal
71 and overload in cultured cardiomyocytes with dose-dependent detrimental effects on intracellular calc
72 Exposure to APDs early in development causes dose-dependent developmental delay and lethality in Caen
75 screens was demonstrated by quantifying the dose-dependent drop in proliferation and increase in dif
79 itro assay), HRMAS NMR identified robust and dose-dependent effect of BMAA on several relevant metabo
82 data indicate that there is a cumulative and dose-dependent effect of repetitive head impacts that in
83 ificantly affect survival of C. dubia, but a dose-dependent effect on growth and reproduction was obs
85 e of ischemia, a consistently favorable cell dose-dependent effect was observed in the change in left
89 hyl]pyridin-3-amine, VA012), which exhibited dose-dependent enhancement of serotonin efficacy, no sig
90 duces apoptosis in VHL-HB stromal cells in a dose-dependent fashion by BAX - caspase-3 pathway unrela
91 ural product, selectively depletes CSCs in a dose-dependent fashion in human triple-negative breast c
92 intracellular Angpt-2 protein in a time- and dose-dependent fashion thereby indirectly reducing the r
93 oblast-to-myofibroblast differentiation in a dose-dependent fashion, and breast cancer clusters recru
94 nted Prdx6, catalase and GSTpi expression in dose-dependent fashion, and halted Nrf2 dysregulation of
95 N rescued cells from UVB-induced toxicity in dose-dependent fashion, which was consistent with SFN's
104 ti-keyhole limpet hemocyanin Ab response was dose-dependent in FR104 recipients and was already appar
105 is CAR-switch combination results in potent, dose-dependent in vivo antitumor activity in xenograft m
109 it compound revealed its ability to induce a dose-dependent inactivation of BU-1 expression in two st
110 cretion; however, CO2 exposure resulted in a dose dependent increase in acid excretion during the ini
113 SH2 overexpression results in a significant, dose-dependent increase in EGFR tyrosine phosphorylation
114 meric ILEI was subsequently found to cause a dose-dependent increase in EpRas cell invasiveness compa
118 imilar for all doses tested, yet there was a dose-dependent increase in insulin secretion and plasma
119 tro, MIOX-siRNA or NAC treatment reduced the dose-dependent increase in p53 expression induced by cis
120 ersistently low pain trajectory, there was a dose-dependent increase in postdischarge ED visits and r
121 gressive hyperinsulinemia, however, caused a dose-dependent increase in the estimated rates of Rd, wh
123 ts: the addition of RPC led to a significant dose-dependent increase of HMF in the cookies and to an
124 rment at 4.5 years but was associated with a dose-dependent increased risk of poor executive function
126 II studies have shown relatively stable and dose-dependent increases in transgene-derived wild-type
127 is well tolerated and results in a profound dose-dependent inhibition of hepatic DNL in overweight a
128 the identification of five drugs that showed dose-dependent inhibition of SOCE in cell-based assay, p
130 r, at human-equivalence (therapeutic) doses, dose-dependent loss of intercellular hepatic TJ-associat
132 eous administration of fitusiran resulted in dose-dependent lowering of the antithrombin level and in
133 directly bind TNFalpha as well as RANKL in a dose dependent manner and that despite expressing higher
134 nd H2S regulate CBS and CSE expressions in a dose dependent manner in cardiomyocytes, and CBS deficie
135 CQA significantly reduced PPAA activity in a dose dependent manner with an IC50 value of about 2mgmL(
136 by both the NLRP3 and AIM2 inflammasome in a dose dependent manner, but not the NLRC4 inflammasome.
144 take strongly associated with ESRD risk in a dose-dependent manner (hazard ratio for highest quartile
145 k of decompensation, mortality, and HCC in a dose-dependent manner (P for trend <0.0001, <0.0001, and
146 ity (MOI = 0.1 PFU/cell) inhibited HCMV in a dose-dependent manner and further induced phosphorylatio
147 roliferation in vitro was reduced by T3 in a dose-dependent manner and increased by insulin at high c
148 Plasma levels of fitusiran increased in a dose-dependent manner and showed no accumulation with re
149 The PRRSV-mediated STAT3 reduction was in a dose-dependent manner as the STAT3 level decreased, alon
150 reversed M3G-induced tactile allodynia in a dose-dependent manner but did not affect motor activity,
151 8 significantly suppressed tumor growth in a dose-dependent manner by inhibiting acquisition of the C
154 d the transcription of its target genes in a dose-dependent manner in the synovial membrane of TMJ.
155 S-phase arrest and cellular senescence in a dose-dependent manner in U2OS and A549 cancer cells as w
156 ell viability of breast cancer cells in a CL dose-dependent manner in vitro using CL photoactivation
157 DII-based marker responded rapidly and in a dose-dependent manner to exogenous auxin via proteasome-
158 cted in mice, mambaquaretin-1 increases in a dose-dependent manner urine outflow with concomitant red
159 of Steinernema glaseri and S. riobrave in a dose-dependent manner when applied on an agar substrate.
160 y, telomerase activity is affected in a gene dose-dependent manner when comparing heterozygote RMRP c
161 ltispecies broth cultures was inhibited in a dose-dependent manner while that of S. gordonii was unaf
162 3.68; P < .001), and the risk increased in a dose-dependent manner with additional weight gain in exc
165 elicase activities are inhibited by Rev in a dose-dependent manner, although ATP-independent helicase
166 vidence that bnMAbs can block infection in a dose-dependent manner, and the more potent bnMAbs will a
167 els of P-407 induced mice were elevated in a dose-dependent manner, and the pancreatic and pulmonary
168 inhibits breast cancer lung metastasis in a dose-dependent manner, associated with blockade of MMP-2
169 ited proliferation of endothelial cells in a dose-dependent manner, but had no effect on EOC cells.
170 proportion of daily breast milk intake in a dose-dependent manner, even after the introduction of so
171 inhibitors blocked telomere elongation, in a dose-dependent manner, in mouse cells overexpressing tel
172 2O3 inhibited de novo dTMP biosynthesis in a dose-dependent manner, increased uracil levels in nuclea
173 associated invariant T cell populations in a dose-dependent manner, resulting in an altered compositi
174 ans and altered biofilm 3D-architecture in a dose-dependent manner, resulting in enlarged and densely
175 ented amphetamine-induced hyperactivity in a dose-dependent manner, similar to the atypical antipsych
176 d, ML-2, that inhibited parasite growth in a dose-dependent manner, thus paving the way for testing i
177 ific DNA damage in a real-time fashion and a dose-dependent manner, we found that the damage response
178 -2, cyto-c, cleaved caspase-3, and PARP in a dose-dependent manner, which indicates AMC induces apopt
179 mones inhibited beta cell proliferation in a dose-dependent manner, while high concentrations of insu
180 ssenger RNA (mRNA) and protein in HMOBs in a dose-dependent manner, while OPG protein remained simila
181 lue light lead to negative phototropism in a dose-dependent manner, with blue light being most effect
182 one, and caffeine maintained responding in a dose-dependent manner, with MDPV being the most potent a
183 early initiation of liver regeneration in a dose-dependent manner, without modifying the peak regene
234 t, cVNS synchronously activates the GSN in a dose-dependent manner; (ii) efferent cVNS enabled by com
237 n knockdown in vivo, with persistent and SNA dose-dependent MGMT silencing confirmed by Western blott
241 ons of 125-500 ng of Diap1 dsRNA resulted in dose-dependent mortality which was shown to be attributa
242 t microinjection of VSV particles leads to a dose-dependent, muscle tissue-tropic, lethal infection i
244 nfirmed SPG5 cases from 28 families, studied dose-dependent neurotoxicity of oxysterols in human cort
245 e gold nanoparticles (GS-AuNPs) are strongly dose-dependent once injection doses are above 15 mg kg(-
248 low Wave Oscillations (SWO, 0.1-1.5 Hz), and dose-dependent phase-amplitude coupling (PAC) between al
249 urthermore, while the strength of priming is dose dependent, plants respond even to very low concentr
251 mpedance biosensing verified in vitro early, dose-dependent quantitative decreases in TJ and cell-sub
252 ptors and used it to investigate in rats the dose-dependent receptor occupancy of eliprodil, a GluN2B
253 es, the protein-polymer conjugates induced a dose dependent reduction in the trans-epithelial electri
254 howed that blocking with octreotide caused a dose-dependent reduction in (64)Cu-MMC(IR800)-TOC uptake
255 tween miR-423-5p and HCN4 was confirmed by a dose-dependent reduction in HCN4 3'-untranslated region
256 ays revealed a highly significant (P < .001) dose-dependent reduction in IgE allergen binding across
257 ence of chronic OXT treatment resulting in a dose-dependent reduction in OXT receptor availability an
259 binant Gal-3 to wild-type mice resulted in a dose-dependent reduction in rolling velocity associated
260 ed antihyperglycemic sitagliptin, produces a dose-dependent reduction in seizures in a mouse model of
261 Male and female mice showed a long-term dose-dependent reduction in thymic cKit(+) lymphoid prog
262 of PrP(Sc) with recombinant GRP78 led to the dose-dependent reduction of protease-resistant PrP(Sc) i
263 ith placebo, canakinumab was associated with dose-dependent reductions in concentrations of hsCRP of
266 tment resulted in statistically significant, dose-dependent reductions in serum phosphate concentrati
268 ken together, our findings indicate that the dose-dependent regulation of tumor metabolism and possib
270 ram of tissue in a statistically significant dose-dependent relationship (globus pallidus: rho = 0.90
271 eriments have unequivocally proven a causal, dose-dependent relationship between the foraging gene an
272 with SMP (ArPPLN1b) revealed that it causes dose-dependent relaxation of apical muscle, tube foot an
274 mutants were assessed against wild-type for dose-dependent resistance to a range of auxins and analo
275 7N9 and H5N1 infection in mice, with a clear dose-dependent response and treatment with MEDI8852 24,
276 ass spectrometric features showed a positive dose-dependent response to meat or fish intake in the in
277 meric network shrinkage responses as well as dose-dependent responses of the UPSS are validated using
279 reverse engineering method and uncovered the dose-dependent rewiring of gene regulatory network durin
280 transplantation assay demonstrated the cell-dose-dependent role of PAR-1 in MLL-AF9 leukemia: PAR-1
281 cefepime MICs is codified in new susceptible dose-dependent (SDD) breakpoints promulgated by the Clin
283 hallenges arising in phase I trials from the dose-dependent side effects of this class of epigenetic
285 73), a selective PI3Kdelta inhibitor, caused dose-dependent suppression of PI3Kdelta pathway hyperact
289 lusion A small but statistically significant dose-dependent T1-weighted signal enhancement was observ
292 Duplications, in contrast, caused not only dose-dependent upregulation but also misexpression of Ih
293 re models revealed that Pals1 functions as a dose-dependent upstream regulator of the crosstalk betwe
296 calixarenes were active in inhibiting, in a dose-dependent way, the LPS-stimulated TLR4 activation a
298 tic stem cells (HSCs) in the bone marrow was dose dependent, with as little as 0.5 Gy causing a signi
299 s on allergen-induced histamine release were dose dependent, with IC50 values ranging between 0.001 a
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