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1 )Lu-lilotomab satetraxetan were included for dosimetry.
2 e assessment of safety, biodistribution, and dosimetry.
3 potential interest for medical and personal dosimetry.
4 ssess pharmacokinetics, biodistribution, and dosimetry.
5 n vitro-to-in vivo extrapolation and reverse dosimetry.
6 8 administration to estimate human radiation dosimetry.
7 lementation is therefore highly dependent on dosimetry.
8 PEB, we performed studies of human radiation dosimetry.
9 ssess pharmacokinetics, biodistribution, and dosimetry.
10 gs relates directly to effective therapeutic dosimetry.
11 ve with improved image quality and radiation dosimetry.
12 remsstrahlung SPECT to improve posttreatment dosimetry.
13 ir comparative biodistribution and radiation dosimetry.
14 valuating (123)I-MNI-420 biodistribution and dosimetry.
15 l (normal organs, lesions) and 3-dimensional dosimetry.
16 l overview of quantitative SPECT imaging for dosimetry.
17 antification-based guidance for radionuclide dosimetry.
18 iNOS levels, and calculated human radiation dosimetry.
19 ondisplaceable binding potential (BPND); and dosimetry.
20 cytometry and in vivo by PET/CT imaging and dosimetry.
21 ll non-Hodgkin lymphoma were included for RM dosimetry.
22 were used to determine pharmacokinetics and dosimetry.
23 y of quantitative imaging for internal renal dosimetry.
24 of long-term toxicity studies and microscale dosimetry.
26 2) 10 days of personal ultraviolet radiation dosimetry; 3) a sun exposure and physical activity diary
29 90)Y radioembolization planned by predictive dosimetry achieved index tumor regression in 8 of 8 pati
30 ilable data demonstrate that posttherapeutic dosimetry after a first treatment cycle predicts the abs
31 ed to evaluate biodistribution and radiation dosimetry after intravenous injection of (18)F-MCL-524.
34 nzyme, Cambridge, Massachusetts, USA) primed dosimetry also provides an easy way to stimulate the upt
37 intake, together with 10 days of personal UV dosimetry and an associated sun-exposure and physical-ac
38 studies: in the first study, human radiation dosimetry and biodistribution of (11)C-metformin were es
39 review is to summarize available data on the dosimetry and dose-response relationships of several the
40 valent uniform dose cannot handle microscale dosimetry and fails to solve the discordance between the
41 ver 48 h for calculation of tissue radiation dosimetry and for evaluation of clinical safety and effi
42 ose Assessment Resource) method for internal dosimetry and in general concordance with the methodolog
43 acroaggregated albumin SPECT/CT personalized dosimetry and intensification concept with (90)Y-loaded
46 Twenty-one tumors were included for voxel dosimetry and parameters describing dose-volume coverage
48 hat such NIRS methods can be used to improve dosimetry and to minimize variations of clinical outcome
49 minimization of long-term toxicity, through dosimetry, and adapted to each individual, including rel
50 n these promising findings, biodistribution, dosimetry, and brain kinetic modeling of (11)C-JNJ-42491
52 is study evaluated the distribution, safety, dosimetry, and efficacy of (111)In-ABY-025 for determini
53 med to assess the feasibility, tolerability, dosimetry, and efficacy of yttrium-90-labelled anti-CD22
55 rement of effective radical doses by radical dosimetry, and proper normalization of the inherent reac
58 Male Sprague-Dawley rats were used to assess dosimetry, antagonistic efficacy via blood pressure meas
59 work, the 3-dimensional Voxel-Based Internal Dosimetry Application (VIDA) and 4D Extended Cardiac Tor
62 e simplified 3-time-point (1, 48, and 144 h) dosimetry approach deviated by at most 4% in both organ-
70 substantial toxicity was consistent with the dosimetry assessments (mean equivalent dose to marrow, 0
71 determine the biodistribution and whole-body dosimetry assessments by positron emission tomography (P
73 based on whole-body/-blood clearance (WB/BC) dosimetry at Memorial Sloan Kettering Cancer Center (MSK
74 based on whole-body/-blood clearance (WB/BC) dosimetry at Memorial Sloan Kettering Cancer Center (MSK
75 ry of (99m)Tc-MAA SPECT/CT and posttreatment dosimetry based on (90)Y time-of-flight (TOF) PET/CT.
77 n (90)Y radioembolization of HCC, predictive dosimetry based on (99m)Tc-MAA SPECT/CT provided good es
79 8 min, Ebeta(+)av = 830 keV) for imaging and dosimetry before (177)Lu-based radionuclide therapy.
81 is first-in-human study demonstrated safety, dosimetry, biodistribution, and successful HER2-targeted
82 ings by a first-in-human (11)C-metformin PET dosimetry, biodistribution, and tissue kinetics study.
83 rience with (18)F-FEOBV, including radiation dosimetry, biodistribution, tolerability and safety in h
85 luded and the male model was applied for the dosimetry calculation, and the mean effective dose was e
99 e group, pretherapeutic (124)I PET/CT lesion dosimetry can be used as a prognostic tool to predict le
103 dination of benzamides and report on initial dosimetry data and the first therapeutic application of
107 moral uptake, biodistribution, and radiation dosimetry data provide strong preclinical evidence that
109 brolizumab in vivo, while providing detailed dosimetry data that may lead to better dosing strategies
110 A-617 therapies were cautiously derived from dosimetry data, but their practical appropriateness has
118 r the study derives from the need to perform dosimetry estimates for the corresponding (90)Y-labeled
123 kinetic properties, test-retest results, and dosimetry estimates of (123)I-MNI-420, a SPECT radiotrac
124 number of disintegrations, and production of dosimetry estimates were performed using the RADAR (RAdi
126 pecific VIDA implementation enables tailored dosimetry estimation for regions most relevant in intrat
127 slation of (64)Cu-FBP8, we performed a human dosimetry estimation using time-dependent biodistributio
128 al formulations, and the predicted radiation dosimetry estimations for some organs varied significant
129 %IDs) corrected for radioactive decay in all dosimetry-evaluable subjects at 15 min and 4 h were 1.9%
130 Similarly in the lungs, the %ID for all dosimetry-evaluable subjects was 4.9% at 15 min after in
135 and tumors determined by (124)I PET/CT-based dosimetry for (131)I therapy of metastatic DTC when the
137 herein assess the cytotoxicity and radiation dosimetry for (68)Ga-NOTA-UBI and a first-in-human evalu
138 s study was to derive PET/CT-based radiation dosimetry for (89)Zr-cetuximab, with special emphasis on
140 d to the development of new, simple chemical dosimetry for low dose detection of gamma radiation.
145 ies for differentiated thyroid cancer, blood dosimetry has been developed to estimate the maximum tol
148 describe the clinical application of (124)I dosimetry in a patient who had radioiodine-refractory th
149 particle transport, and thus attain accurate dosimetry in cell culture systems, which will greatly ad
150 ing provides a better assessment of lesional dosimetry in contrast to traditional I-131 whole body sc
151 ssess safety, biodistribution, and radiation dosimetry in humans for the highly selective sigma-1 rec
153 planned tumor dose [T(plan) D]) and nontumor dosimetry in patients treated by (90)Y-loaded glass micr
155 ticular, we discuss the role of (124)I-based dosimetry in targeting of the sodium-iodine symporter an
156 t optimization of a personalized Monte Carlo dosimetry in the context of SIRT was confirmed in this s
157 was to evaluate SPECT- and MR imaging-based dosimetry in the first patients treated with (166)Ho rad
158 ow of the importance of in vitro and in vivo dosimetry in the hazard assessment and ranking of engine
159 7 of 8 patients, including 2 by sublesional dosimetry, in 1 of whom there was radioembolization lobe
160 ety, biodistribution, and internal radiation dosimetry, in humans with thyroid cancer, of (18)F-tetra
161 col based on such a methodology for in vitro dosimetry, including detailed standardized procedures fo
162 rom MgO:Li,Ce,Sm has suitable properties for dosimetry, including high sensitivity to ionizing radiat
165 ith the use of (166)Ho-microspheres, in vivo dosimetry is feasible on the basis of both SPECT and MR
166 la: see text] demonstrates that pretreatment dosimetry is particularly suitable for minimizing radiat
168 Bq/kg dose was not feasible because of organ dosimetry limits; however, 3 assigned patients were eval
169 ssed the feasibility of generating radiation dosimetry maps in liver regions with high and low (90)Y
175 biodistribution, pharmacokinetics, estimated dosimetry, nano-SPECT/CT, and bioluminescent imaging sug
176 will significantly alter in vitro behavior (dosimetry, NP uptake, cytotoxicity), as well as in vivo
177 ET/CT was used to characterize the radiation dosimetry of (11)C-DPA-713, a specific PET ligand for th
178 e use of (11)C-laniquidar by determining the dosimetry of (11)C-laniquidar using whole-body PET studi
180 he initial clinical experience and radiation dosimetry of (18)F-DCFBC in men with metastatic PCa.
181 tudy was to evaluate the biodistribution and dosimetry of (18)F-FAZA in non-small cell lung cancer pa
183 e safety, feasibility, pharmacokinetics, and dosimetry of (18)F-MFBG in neuroendocrine tumors (NETs).
185 the biodistribution, kinetics, and radiation dosimetry of (64)CuCl2 in humans and to assess the abili
187 e biodistribution and estimate the radiation dosimetry of (68)Ga-ABY-025 for 2 different peptide mass
188 macokinetics, biodistribution, and radiation dosimetry of (68)Ga-bombesin antagonist (68)Ga-DOTA-4-am
192 -in-human study, we evaluated the safety and dosimetry of (89)Zr-pertuzumab PET/CT for human epiderma
193 to evaluate agreement between the predictive dosimetry of (99m)Tc-MAA SPECT/CT and posttreatment dosi
194 usly reported pharmacokinetic properties and dosimetry of 8, make it a potential agent for both PET i
195 mans was designed to evaluate the safety and dosimetry of a cellular proliferative marker, N-(4-(6,7-
197 , whole-organ biodistribution, and radiation dosimetry of LMI1195 were evaluated in a phase 1 clinica
199 d the pharmacokinetics, biodistribution, and dosimetry of pembrolizumab in vivo, accomplished through
207 antitative SPECT/CT imaging, a set of kidney dosimetry phantoms and their spherical counterparts was
209 e study was conducted to calculate the tumor dosimetry (planned tumor dose [T(plan) D]) and nontumor
210 osimetry technique--personalized Monte Carlo dosimetry (PMCD)-based on patient-specific data and Mont
217 18)F-D4-FCH is a safe PET radiotracer with a dosimetry profile comparable to other common (18)F PET t
218 (18)F-ICMT-11 is a safe PET tracer with a dosimetry profile comparable to other common (18)F PET t
219 lects PARP expression and that its radiation dosimetry profile is compatible with those of agents cur
220 ety, biodistribution, and internal radiation dosimetry profiles of (18)F-D4-FCH in 8 healthy human vo
221 ety, biodistribution, and internal radiation dosimetry profiles of (18)F-ICMT-11 in 8 healthy human v
222 bes was conducted that included internal BPA dosimetry, progression to adenocarcinoma with aging and
225 gamma-camera imaging as part of the clinical dosimetry protocol, determination of the whole-body acti
226 ry techniques conventionally used in hepatic dosimetry provide a first-order estimate of absorbed dos
227 tine use of WB/BC dosimetry without lesional dosimetry provided no OS advantage when compared with em
228 tine use of WB/BC dosimetry without lesional dosimetry provided no OS advantage when compared with em
229 e addressed in clinical trials incorporating dosimetry-related concepts for determining the amount of
233 ne, although the impact of reducing lesional dosimetry requires attention and further investigation.
234 After encouraging preclinical and human dosimetry results for the novel estrogen receptor (ER) P
236 sionate use, describing the biodistribution, dosimetry, safety, and clinical activity of radretumab.
237 To evaluate radiotracer biodistribution and dosimetry, serial whole-body images were acquired immedi
238 and AOP approaches and suggest that internal dosimetry should be monitored to advance an understandin
241 of a proven 3-dimensional (3D) personalized dosimetry software, 3D-RD, and applied to the myeloablat
242 cted to improve the relevance of small-scale dosimetry studies and thus to accelerate the optimizatio
244 istribution, pharmacokinetics, SPECT/CT, and dosimetry studies were performed to assess the bioequiva
252 n that context, a 3-dimensional personalized dosimetry technique--personalized Monte Carlo dosimetry
253 icrosphere distribution confirmed that (90)Y dosimetry techniques conventionally used in hepatic dosi
255 mics-based approaches to forward and reverse dosimetry, there is currently a lack of user-friendly, f
257 quantitation of SPECT imaging and its use in dosimetry to guide therapies, it is desirable to underst
259 Radiobiologic and quantitative imaging-based dosimetry tools are now available that enable rational i
261 within +/-9% of that measured by using film dosimetry under the condition of matched-phantom geometr
262 otracers, preclinical (i.e., animal-derived) dosimetry underestimates the ED to humans, in the curren
263 s should be done to enhance the precision of dosimetry, validate the maximum tolerable dose, and eval
264 ent communication offers a revision of fetal dosimetry values calculated from recently published huma
280 n as a function of time were determined, and dosimetry was performed for a range of organs including
295 t of tissue density heterogeneities (TDH) on dosimetry when using a DK method and to propose a simple
297 (11)C-sarcosine showed a favorable radiation dosimetry with an effective dose estimate of 0.0045 mSv/
298 After stimulation with thyrotropin alfa, dosimetry with iodine-124 positron-emission tomography (
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