ライフサイエンスコーパス: double-stranded

1 to which (single-strand) oligos rather than (double-stranded) adaptors are ligated.

2 tag containing a combination of alternating double-stranded and single-stranded DNA (dsDNA and ssDNA

3 ust uracil DNA glycosylase that only acts on double-stranded and single-stranded uracil-containing DN

4 ple DNA into circular vectors, which contain double-stranded barcodes for computational error correct

5 e a method, termed CypherSeq, which combines double-stranded barcoding error correction and rolling c

6 s enhanced, and the complex was recruited to double-stranded break (DSB) sites in response to etoposi

7 It has been reported that double-stranded break (DSB)-induced small RNAs (diRNAs)

8 te ICL removal and repair of the ensuing DNA double-stranded break by homology-dependent repair (HDR)

9 structure, thereby hiding telomere ends from double-stranded break repair and ATM signaling, whereas

10 on human chromosome 2, in which synchronized double stranded breaks (DSB) within the echinoderm micro

11 s ATM and DNA-PKcs through the generation of double stranded breaks (DSBs) in murine macrophage genom

12 egulate DNA topology by generating transient double stranded breaks during replication and transcript

13 frequently during healing of induced nuclear double-stranded breaks (DSB) but the resulting nuclear i

14 k radiation showed a significant increase in double-stranded breaks (DSB) in the DNA of parotid saliv

15 -resistant cells regain RAD51 loading to DNA double-stranded breaks (DSBs) and stalled replication fo

16 rly remarkable in the examination of how DNA double-stranded breaks (DSBs) are repaired, with many co

17 A DNA-damaging agent that induces DNA double-stranded breaks (DSBs) does not affect the intera

18 Cas9 creates targeted double-stranded breaks (DSBs) in the genome.

19 emplate-driven repair pathway that mends DNA double-stranded breaks (DSBs), and thus helps to maintai

20 deaminases to introduce changes (rather than double-stranded breaks and donor templates) and offers p

21 ed for only certain types of damage, such as double-stranded breaks and interstrand crosslinks.

22 These genome-editing nucleases make double-stranded breaks at specified loci, and desired ch

23 x BRCA1-BARD1 functions in the repair of DNA double-stranded breaks by homologous recombination.

24 evidence of ATR inhibition and enhanced DNA double-stranded breaks in response to the combination.

25 gative plasmids by introducing site-specific double-stranded breaks in target DNA.

26 (CPT), PIAS3 contributes to formation of DNA double-stranded breaks.

27 ortion of S/G2-phase cells transduced by the double-stranded but not the single-stranded recombinant

28 tion is required for repairing lesions using double-stranded, but not single-stranded DNA as a templa

29 triggered by self-RNAs possessing regions of double-stranded character.

30 Double-stranded chopping products are selectively loaded

31 separate the Watson and Crick strands of the double-stranded chromosomal DNA in a single cell and to

32 t during homologous recombination, repair of double stranded DNA breaks, and integron recombination.

33 spired by homology dependent pairing between double stranded DNA in bacteria.

34 rus (ASFV), is a highly structurally complex double stranded DNA virus.

35 robe (single stranded DNA-ssDNA) and hybrid (double stranded DNA-dsDNA) both via 3-NT reduction and g

36 e of introducing sequence specific breaks in double stranded DNA.

37 hematosus (SLE), IgE antibodies specific for double-stranded DNA (dsDNA) activated plasmacytoid dendr

38 ently repressed to prevent the generation of double-stranded DNA (dsDNA) breaks in cycling large pre-

39 ing via homology-directed repair (HDR) after double-stranded DNA (dsDNA) cleavage facilitates functio

40 We demonstrate that, unlike double-stranded DNA (dsDNA) donors with central heterolo

41 cant correlation between the release of host double-stranded DNA (dsDNA) following rhinovirus infecti

42 Each strain encodes a 9.8- to 9.9-kb linear double-stranded DNA (dsDNA) genome with large inverted t

43 d to bind RNA in addition to their canonical double-stranded DNA (dsDNA) ligand.

44 rategies that enable recognition of specific double-stranded DNA (dsDNA) regions has been a longstand

45 olves direct interactions between homologous double-stranded DNA (dsDNA) segments.

46 onjugate accumulation was dependent upon the double-stranded DNA (dsDNA) sensor cyclic GMP-AMP syntha

47 e can form a nucleoprotein filament (NPF) on double-stranded DNA (dsDNA) that is capable of unwrappin

48 cryo-EM), we show that the binding of target double-stranded DNA (dsDNA) to a type I-F CRISPR system

49 tion releases granule proteins together with double-stranded DNA (dsDNA) to form extracellular fibers

50 ies to prevent active infection with certain double-stranded DNA (dsDNA) viruses after allogeneic hem

51 Human adenoviruses (Ad) are double-stranded DNA (dsDNA) viruses associated with infe

52 Ascoviruses are double-stranded DNA (dsDNA) viruses that attack caterpil

53 The ability to directly detect double-stranded DNA (dsDNA) without sequence-preference

54 u magnetic nanoparticles functionalized with double-stranded DNA (dsDNA), a sequence of the breast ca

55 dynamics, the division between the rates of double-stranded DNA (dsDNA), single-stranded RNA (ssRNA)

56 nsible for pairing the ssDNA with homologous double-stranded DNA (dsDNA), which serves as the templat

57 red by host defenses that detect cytoplasmic double-stranded DNA (dsDNA).

58 are studied as models for viruses containing double-stranded DNA (polymer) and condensing proteins (p

59 oprotein C1/C2 (hnRNPC1/C2) can also bind to double-stranded DNA and function in trans as a vitamin D

60 e CTM domain) that binds efficiently to both double-stranded DNA and G-quadruplex (G4) DNA.

61 dro-2'-deoxyguanine (8-oxoG) often occurs in double-stranded DNA and poses a threat to genomic integr

62 psid shell, must be reverse transcribed into double-stranded DNA and released from the capsid (in a p

63 Double-stranded DNA and RNA adopt different helical conf

64 ting such models have been reported that use double-stranded DNA as donors, but their efficiency is t

65 assembly of head-to-head CMGs that encircle double-stranded DNA at the origin, the two CMGs must pas

66 hermore, our data indicate that the entry of double-stranded DNA beyond a short threshold distance fr

67 recombination (HR) is a crucial pathway for double-stranded DNA break (DSB) repair.

68 al chromatin organization before and after a double-stranded DNA break (DSB), to estimate the level o

69 ast DNAs insert into nuclear genomes through double-stranded DNA break repair.

70 is a DNA helicase/nuclease that functions in double-stranded DNA break repair.

71 nce with either event protects bacteria from double-stranded DNA breakage and TLD.

72 Recognition and repair of double-stranded DNA breaks (DSB) involves the targeted r

73 Unrepaired DNA lesions, such as single- and double-stranded DNA breaks (SSBs and DSBs), and single-s

74 pyogenes (SpCas9) is more active in creating double-stranded DNA breaks at 37 degrees C than at 22 de

75 gous recombination compete for the repair of double-stranded DNA breaks during the cell cycle.

76 Here we introduced double-stranded DNA breaks into the nuclear genome of to

77 In bacteria, the repair of double-stranded DNA breaks is modulated by Chi sequences

78 cycle progression through mitosis following double-stranded DNA breaks leads to the formation of mic

79 antage that it does not require formation of double-stranded DNA breaks or provision of a donor DNA t

80 ed replication forks, insufficient repair of double-stranded DNA breaks, and improper segregation of

81 et (UV)-C radiation and reagents that induce double-stranded DNA breaks, but exhibit normal responses

82 BRCA1 has no equivalent role at chromosomal double-stranded DNA breaks, indicating that tandem dupli

83 Although fluoroquinolones stabilize double-stranded DNA breaks, the antibacterial thiophenes

84 Mre11 and Rad50 to coordinate the repair of double-stranded DNA breaks.

85 ls by inhibiting topoisomerases and inducing double-stranded DNA breaks.

86 converting single-stranded DNA lesions into double-stranded DNA breaks.

87 n a large set of 438 GQ forming sequences in double-stranded DNA by integrating fluorescence measurem

88 g specific sequences along the backbone of a double-stranded DNA carrier.

89 sembly and utilization of a surface-attached double-stranded DNA catenane composed of two intact inte

90 ersion of one base pair into another without double-stranded DNA cleavage, excess stochastic insertio

91 ion of all four transition mutations without double-stranded DNA cleavage.

92 e complex for telomeric quadruplex DNA and a double-stranded DNA control.

93 At these double-stranded DNA ends, RarA couples the energy of ATP

94 genetic transfer by producing recombinogenic double-stranded DNA ends.

95 s stimulated by single-stranded DNA gaps and double-stranded DNA ends.

96 ctions, the viral genome is established as a double-stranded DNA episome.

97 nthetic DNA, through the in vivo excision of double-stranded DNA from an episomal replicon by CRISPR/

98 ination events are associated with repair of double-stranded DNA gaps and/or involve Mlh1-independent

99 illus subtilis phage whose uracil-containing double-stranded DNA genome encodes distant homologs of b

100 phage, the DNA packaging nanomotor packs its double-stranded DNA genome into the virus capsid.

101 The double-stranded DNA genome is covalently circularized at

102 ith T=13 icosahedral geometry and encloses a double-stranded DNA genome that measures 121kbp.

103 enovirus (HAdV), a medium-sized virus with a double-stranded DNA genome, needs to be identified.

104 ruses, which we denote magroviruses, possess double-stranded DNA genomes of 65 to 100 kilobases in si

105 inner cavity, large enough to accommodate a double-stranded DNA helix, as well as a protruding Tower

106 bulins (especially IgM, P < .0001), and anti-double-stranded DNA IgG (P < .05).

107 on) to analyze the differential stability of double-stranded DNA in complex with either cisplatin or

108 We demonstrate that RarA binds to double-stranded DNA in its ATP-bound state and single-st

109 TRIM29 is also highly induced by cytosolic double-stranded DNA in myeloid dendritic cells.

110 The double-stranded DNA is tightly packed in the capsid as a

111 finely designing the curvature and torsion, double-stranded DNA knots were accessed by hybridizing a

112 The final produced long nicked double-stranded DNA loses the ability to protect AgNPs f

113 tes DNA topology by transiently breaking one double-stranded DNA molecule (cleavage), allowing a seco

114 s (Cas) that utilize RNA to find and cut the double-stranded DNA molecules at specific locations.

115 ombination, in which the repair of breaks in double-stranded DNA molecules is taking place with a hel

116 l plastid (chloroplast) genomes are circular double-stranded DNA molecules, typically between 100 and

117 Hop1-promoted intermolecular pairing between double-stranded DNA molecules.

118 bridging, condensation, and pairing between double-stranded DNA molecules.

119 linear HCR is a hairpin-free system in which double-stranded DNA monomers could dendritically assembl

120 Due to the linear double-stranded DNA nature of the adenovirus genome, the

121 and chromosomal gene conversion with either double-stranded DNA or single-stranded oligonucleotide d

122 y transferred in trans from ssNucs to either double-stranded DNA or ssDNA.

123 action of cauliflower mosaic virus (CaMV), a double-stranded DNA pararetrovirus, with the model plant

124 s for T4, we show how the energetic costs of double-stranded DNA phages scale with the capsid size, r

125 ages from all three major families of tailed double-stranded DNA phages.

126 As scaffold, we employed a double-stranded DNA rotaxane for its ability to undergo

127 Here, we show that mice deficient in the double-stranded DNA sensor AIM2 are protected from both

128 ize the replication origin (oriC) by binding double-stranded DNA sequences (DnaA-boxes); subsequently

129 PR)-associated 9 (Cas9) endonuclease cleaves double-stranded DNA sequences specified by guide RNA mol

130 We find that double-stranded DNA stimulates ATP hydrolysis by hMRN ov

131 es with a CRISPR RNA (crRNA) and cleaves the double-stranded DNA target complementary to the crRNA gu

132 Escherichia coli Cascade bound to a foreign double-stranded DNA target.

133 iosensor platform starting from an initially double-stranded DNA target.

134 The RNA-guided Cpf1 nuclease cleaves double-stranded DNA targets complementary to the CRISPR

135 nuclease active sites in the degradation of double-stranded DNA targets.

136 t single-stranded RNA of the viral genome to double-stranded DNA that is then integrated into the DNA

137 genome of HIV-1 is reverse transcribed into double-stranded DNA that ultimately integrates into the

138 unreported conductance states that occur as double-stranded DNA translocates through a 2.4 nm solid-

139 V E2.IMPORTANCE The papillomavirus (PV) is a double-stranded DNA tumor virus infecting cervix, mouth,

140 Human cytomegalovirus (HCMV) is an enveloped double-stranded DNA virus that causes severe disease in

141 Human cytomegalovirus (HCMV) is a large, double-stranded DNA virus that causes significant human

142 African swine fever virus, a double-stranded DNA virus that infects pigs, is the only

143 acmanvirus is a newly discovered icosahedral double-stranded DNA virus that was isolated from an envi

144 e fever virus (ASFV) is a highly pathogenic, double-stranded DNA virus with a marked tropism for cell

145 dataset to present a global map of abundant, double-stranded DNA viruses complete with genomic and ec

146 and complex genomes make evolution in these double-stranded DNA viruses more efficient than that in

147 f small viruses than in the context of large double-stranded DNA viruses such as herpesviruses.

148 Papillomaviruses (PVs) are small, double-stranded DNA viruses that are responsible for cer

149 simplex virus 1 (HSV-1) and HSV-2 are large, double-stranded DNA viruses that cause lifelong persiste

150 Papillomaviruses are small, double-stranded DNA viruses that encode the E2 protein,

151 s) are an ancient and heterogeneous group of double-stranded DNA viruses that preferentially infect t

152 e that Epstein-Barr virus and possible other double-stranded DNA viruses use TRIM29 to suppress local

153 ighlight the emergence of previously unknown double-stranded DNA viruses which delineate and extend t

154 Many double-stranded DNA viruses which parasitize such hosts,

155 ckaging is strongly conserved in the complex double-stranded DNA viruses, including the herpesviruses

156 Many double-stranded DNA viruses, such as Epstein-Barr virus,

157 Unlike double-stranded DNA viruses, which pump their genome int

158 jelly-roll protein that can be found in many double-stranded DNA viruses.

159 ity to telomeric DNA substrates comprised of double-stranded DNA with a 3' single-stranded extension.

160 ApoE4 undergoes nuclear translocation, binds double-stranded DNA with high affinity (low nanomolar),

161 d 3-way junction rather than with single- or double-stranded DNA with overhangs.

162 ct a single DNA-nanogold conjugate, an 84-bp double-stranded DNA with two 5-nm nanogold particles for

163 plex led to the release of the AuNPs-S2 from double-stranded DNA(dsDNA) and the recovery of the ECL s

164 facilitation of primer strand invasion into double-stranded DNA, and a suppression of non-homologous

165 igher in single-stranded DNA (ssDNA) than in double-stranded DNA, and copying the resulting uracils c

166 ystal structures of cyclic GMP-AMP synthase, double-stranded DNA, and inhibitors within the enzymatic

167 Upon binding double-stranded DNA, cyclic GMP-AMP synthase synthesizes

168 hich preferentially bind the minor groove of double-stranded DNA, inhibit vaccinia virus infection by

169 P-AMP synthase (cGAS), a cytosolic sensor of double-stranded DNA, is activated in autoinflammatory di

170 e analyze smFRET data of structurally rigid, double-stranded DNA-oligonucleotides in aqueous buffer a

171 ulator of interferon genes, a key adaptor in double-stranded DNA-sensing pathway, followed by its rap

172 ble an Mcm2-7 double-hexamer around adjacent double-stranded DNA.

173 f potato is further able to bind and distort double-stranded DNA.

174 y structure which appears capable of binding double-stranded DNA.

175 by ATP, which allows efficient processing of double-stranded DNA.

176 les that are mixtures of single-stranded and double-stranded DNA.

177 enables the translocation and processing of double-stranded DNA.

178 4) complex formation immediately adjacent to double-stranded DNA.

179 ate hydrolysis-dependent translocation along double-stranded DNA.

180 The latter allows MjAgo to process long double-stranded DNAs, including circular plasmid DNAs an

181 urrent genome-editing technologies introduce double-stranded (ds) DNA breaks at a target locus as the

182 e-stranded (ss) RNAs with cognate homologous double-stranded (ds) DNA in vitro Using magnetic tweezer

183 gle-stranded (ss) DNA region within a longer double-stranded (ds) DNA molecule.

184 The positions have been demonstrated for double-stranded (ds) DNA using NMR spectroscopy.

185 s were labeled with three distinct monolayer double-stranded (ds) DNA-gold nanoparticles (DNA-AuNPs).

186 DNA, which catalyses pairing with homologous double-stranded (ds) DNA.

187 rcular DNA in either single-stranded (SS) or double-stranded (DS) form.

188 We oxidized a 32 base pair (bp) double-stranded (ds) oligonucleotide representing exon 7

189 ate that turnover of damage-induced nuclear, double-stranded (ds) RNA requires additional phosphoryla

190 n of adenosine (A) to produce inosine (I) in double-stranded (ds) RNA structures, a process known as

191 Surprisingly, Cap-0 and 5'ppp double-stranded (ds) RNAs bind to RIG-I with nearly iden

192 Moreover, TEC were stimulated with genomic double-stranded (ds)DNA or IFN.

193 and Toll-like receptors recognize microbial double-stranded (ds)DNA, dsRNA, and LPS to induce the ex

194 Here, we report that linear DNAs (single and double stranded) engage in a high-efficiency HDR mechani

195 In the presence of double-stranded genomic lesions, the unidirectional conv

196 were applied for the screening test for the double stranded HLA-B*58:01 and HLA-B*57:01 genes that a

197 und that XPA binds different single-stranded/double-stranded junction DNA substrates with a common su

198 eishmania Viannia (L.V.) subgenus harbor the double-stranded Leishmania RNA virus 1 (LRV-1), previous

199 Here, we report a double-stranded locked nucleic acid (dsLNA) biosensor fo

200 closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter co

201 Unzipping of double-stranded nucleic acids by an electric field appli

202 When terminally attached to double-stranded nucleic acids via the 5' phosphate group

203 pectroscopy and HPLC on different single and double stranded oligonucleotides containing a cyclobutan

204 ing adequate to melt non-covalently attached double-stranded oligonucleotides in solution.

205 r systems, from dinucleotides to single- and double-stranded oligonucleotides.

206 into nanocarrier by intercalating inside the double-stranded pH-responsive DNAs on the GNR surface to

207 cond strategy, using magnetic capture of the double-stranded product followed by denaturing, produces

208 ss complex was dependent on RHA binding to a double-stranded region of the primer binding site (PBS)-

209 geting unmethylated sequences generate local double stranded regions resulting to digestion of unmeth

210 rium Bacillus thuringiensis; next-generation double-stranded ribonucleic acid (dsRNA) PIPs have been

211 lasmid for in planta transient expression of double stranded RNA (dsRNA) homologous to the acetylchol

212 propose that bivalent interactions with the double stranded RNA binding domain and the basic region

213 Destabilization of the double stranded RNA was measured as a function of number

214 ly recognize more complex structures such as double stranded RNA.

215 Adenosine deaminases acting on double-stranded RNA (ADARs) catalyze the deamination of

216 MDA5 is a cytosolic sensor of double-stranded RNA (ds)RNA including viral byproducts a

217 essive steps in mRNA degradation and prevent double-stranded RNA (dsRNA) accumulation, whereas the vi

218 We also tested the effects of injecting double-stranded RNA (dsRNA) against XDH1, XDH2, or both.

219 ions that fully separate the strands of long double-stranded RNA (dsRNA) and allow the released RNAs

220 ressed by ADARs beyond their RNA editing and double-stranded RNA (dsRNA) binding functions.

221 abundance 22-nucleotide siRNAs produced from double-stranded RNA (dsRNA) by DCL4 and DCL2, respective

222 Long double-stranded RNA (dsRNA) can silence genes of matchin

223 Studies on double-stranded RNA (dsRNA) degradation by dsRNases and

224 Topical application of pathogen-specific double-stranded RNA (dsRNA) for virus resistance in plan

225 Viruses induce double-stranded RNA (dsRNA) in the host cells.

226 entation machinery, mediated in part through double-stranded RNA (dsRNA) induction.

227 are positive-sense RNA viruses that generate double-stranded RNA (dsRNA) intermediates during replica

228 tinct Dicer-like (DCL) proteins that process double-stranded RNA (dsRNA) into small-interfering RNAs

229 Double-stranded RNA (dsRNA) is a common by-product of vi

230 that the biogenesis of viral siRNAs from IAV double-stranded RNA (dsRNA) precursors in infected cells

231 eviously, our group has shown that noncoding double-stranded RNA (dsRNA) released during wounding is

232 storically been used as a model to study the double-stranded RNA (dsRNA) Reoviridae family, the membe

233 t encode an ExoN, which functions to degrade double-stranded RNA (dsRNA) replication intermediates.

234 only egress, cells were transfected with the double-stranded RNA (dsRNA) targeting an individual ESCR

235 Injection of double-stranded RNA (dsRNA) targeting gene coding for in

236 ting the cascade of antiviral responses that double-stranded RNA (dsRNA) triggers in host cells.

237 The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1)

238 Specifically, efficient synthesis of double-stranded RNA (dsRNA) within infected cells is req

239 Invertebrates rely on Dicer to cleave viral double-stranded RNA (dsRNA), and Drosophila Dicer-2 dist

240 nting translational shutdown mediated by the double-stranded RNA (dsRNA)-activated kinase PKR and the

241 In particular, NP associates with the double-stranded RNA (dsRNA)-activated protein kinase (PK

242 Injection of female mosquitoes with either double-stranded RNA (dsRNA)-ALAT1 or dsRNA ALAT2 signifi

243 y, a previously unidentified mutation in the double-stranded RNA (dsRNA)-binding domain (I64T) decrea

244 ble protein I (RIG-I)-like receptors (RLRs), double-stranded RNA (dsRNA)-dependent protein kinase rec

245 mplex and the viral replication intermediate double-stranded RNA (dsRNA).

246 In this study, we analyzed how non-coding double-stranded RNA (dsRNAs) act as a DAMP in the skin a

247 kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulate

248 ory cytokine and type I IFN responses to the double-stranded RNA analogue poly(I:C) are reduced in mo

249 Double-stranded RNA and the synthetic analog polyinosini

250 NAs also activate PKR constructs lacking the double-stranded RNA binding domain and bind to a basic r

251 ng at the Q/R site of GRIA2 Furthermore, the double-stranded RNA binding domains of ADAR3 are require

252 non-catalytic factors containing one or more double-stranded RNA binding motif (dsRBM) that play impo

253 we retrace the evolutionary history of plant double-stranded RNA binding proteins (DRBs), a group of

254 factors activated by the detection of viral double-stranded RNA by pattern-recognition receptors (RI

255 cleaved precursor fragments are converted to double-stranded RNA by RNA-dependent RNA polymerase 6 (R

256 The sensor RIG-I detects double-stranded RNA derived from RNA viruses.

257 the process of reassortment, whereby the 11 double-stranded RNA genome segments are exchanged among

258 e of toll-like receptor 3 and the binding of double-stranded RNA in the pathogenesis of sterile injur

259 ally, pretreatment with toll-like receptor 3/double-stranded RNA ligand inhibitor led to a reduction

260 kness behavior, single-stranded RNA viruses, double-stranded RNA ligands, and IFNs shared pathways in

261 raphic data demonstrate a mechanism in which double-stranded RNA mediates enzyme dimerization.

262 h broadly acting, because it is triggered by double-stranded RNA molecules derived from virtually any

263 enosine deaminases that edit and destabilize double-stranded RNA reducing its immunostimulatory activ

264 plex of VP1, VP4, and VP6 and a genome of 10 double-stranded RNA segments.

265 a RNA helicase Dhx9, Nlrp9b recognizes short double-stranded RNA stretches and forms inflammasome com

266 mmunity is independent of a 5' triphosphate, double-stranded RNA structure, or the primary sequence o

267 itro for efficient nuclease activity against double-stranded RNA substrates, particularly at lower te

268 gulation of AsFAR expression by injection of double-stranded RNA suppresses ovarian development and f

269 ny Leishmania (Viannia) parasites harbor the double-stranded RNA virus Leishmania RNA virus 1 (LRV1),

270 isolates of L. braziliensis (>25%) contain a double-stranded RNA virus named Leishmaniavirus 1 (LRV1)

271 catalyzed by Adenosine DeAminases acting on double-stranded RNA(dsRNA) (ADAR), occurs predominantly

272 vation with poly(I:C), a synthetic analog of double-stranded RNA, and longitudinally imaged postsynap

273 er-235 phosphorylated NS5A co-localized with double-stranded RNA, consistent with its role in HCV rep

274 ich encodes an innate immune sensor of viral double-stranded RNA, depends on the interferon regulator

275 Upon sensing double-stranded RNA, OAS produces 2',5'-oligoadenylates

276 find that SMAD3 binds poorly to single- and double-stranded RNA, regardless of sequence.

277 Double-stranded RNA-binding domains (dsRBDs) are commonl

278 The double-stranded RNA-binding protein DRB4 of Arabidopsis

279 uding those coding for Dicer, Argonaute, and double-stranded RNA-binding proteins (dsRBP) as well as

280 ough inhibiting eIF-2alpha kinases including double-stranded RNA-dependent protein kinase (PKR), whic

281 the eggs laid by females injected with Kr-h1 double-stranded RNA.

282 f defense against viral infection by sensing double-stranded RNA.

283 nts, thus increasing intracellular levels of double-stranded RNA.

284 (MAVS) by the antimicrobial peptide LL37 and double stranded-RNA released from necrotic cells.

285 Double-stranded-RNA (dsRNA)-activated protein kinase R (

286 The endoribonuclease RNase III cleaves double stranded RNAs, which can be formed during the int

287 Double-stranded RNAs (dsRNA) produced during human cytom

288 Recent new studies demonstrate that spraying double-stranded RNAs (dsRNAs) and small RNAs (sRNAs) tha

289 Feeding with SmedOB1 double-stranded RNAs (dsRNAs) led to homeostasis abnorma

290 It relies on plants stably expressing double-stranded RNAs (dsRNAs) that target essential gene

291 terize the AlucJHEH gene, three fragments of double-stranded RNAs (dsRNAs) were designed to target di

292 ble elements that leads to the production of double-stranded RNAs (dsRNAs).

293 whereas Dicer-2 makes 21-nt siRNAs from long double-stranded RNAs (dsRNAs).

294 that Botrytis can take up external sRNAs and double-stranded RNAs (dsRNAs).

295 RNA polymerases (RDRs) catalyze synthesis of double-stranded RNAs that can serve to initiate or ampli

296 tion initiation factor upon binding to viral double-stranded RNAs.

297 ene expression from both single-stranded and double-stranded (self-complementary) recombinant AAV2 ve

298 ses, the associated DNA is not in a standard double-stranded state.

299 s, methylated cytosines can be found in both double-stranded (symmetric) and single-stranded (asymmet

300 Higher ratios of HCV double-stranded to single-stranded RNA (ssRNA) correlate