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1 t) and detect droplets containing two cells (doublets).
2 ly, rectifying the strong correlation in the doublet.
3 in state having a ground-state "non-Kramers" doublet.
4 le for generating the larger isoform of each doublet.
5 Stylonychia pustulata) is the mirror-imaged doublet.
6 ontaining intermediates on the PksJ T-domain doublet.
7 )H NMR spectra to the alpha-glucose anomeric doublet.
8 d, in which every major peak is split into a doublet.
9 riples interrupted by a C*G-C triple and C-G doublet.
10 array in a precise location on each axonemal doublet.
11 ith no significant mixing even in the higher doublets.
12 otors concentrates at the distal tips of the doublets.
13 ositioning and number of ciliary microtubule doublets.
14 owed by oscillatory bending between pairs of doublets.
15 her ixabepilone or paclitaxel platinum-based doublets.
16 tra consisted of a sextet and two quadrupole doublets.
17 ks were variable among different microtubule doublets.
18 uces both the EPSP-AP coupling and evoked AP doublets.
19 etry break, and moreover it often involved 2 doublets.
20 ynein-dependent "adhesive force" between the doublets.
21 y of dynein for the B-subtubule of the outer doublets.
22 ducts with M and M+2 ions resembling bromine doublets.
23 d 3D cell aggregates and micropatterned cell doublets.
24 ty associated with other targeted biological doublets.
25 d to incorporate mixing of the two e orbital doublets (30%) that results from a lowering of the ideal
26 .7% of patients received a carboplatin-based doublet, 64.9% and 31.3% received docetaxel, and 0% and
28 e kinocilia contain 9 peripheral microtubule doublets, a central microtubule pair, and 9 connecting r
29 devoid of ferritin but contained the central doublet and features arising from what appear to be Fe(I
30 spoke has a distinct base that docks to the doublet and is linked to different inner dynein arms.
32 transition-metal systems, leaving a Kramers doublet and quartet with effective angular momentum of J
33 Here we report observations of the Na (I) doublet and the Wing-Ford molecular FeH band in the spec
38 etic effects drive the assembly of staggered doublets and triplets of nanorods that are moving in the
39 rapy (one or two lines, including a platinum doublet) and crizotinib and had subsequent disease progr
40 gnet relaxes via the second-excited Kramers' doublet, and, when doped into a diamagnetic matrix at th
42 dominantly at but not limited to pyrimidine doublets; and from multiple lamps recommended for UV sha
44 e-cell electron cryotomography, we show that doublets are abundant in bacterial cells containing low-
48 quations of motion for the flagellum and its doublets are derived from mechanical equilibrium princip
49 wed that dendrogram-based I(X 1; X 2; Y) and doublets are helpless for discovering pair-wise gene int
52 ests function: The data imply that most EGFR doublets are NOT consistent with a 'driver and passenger
53 get is included, more than one-third of EGFR doublets are one of five specific missense pairs: G719/E
56 Median overall survival was improved in the doublet arm to 28.0 months (95% CI, 23.5 to 31.5 months)
64 ed to mild proteolysis, we observed pairs of doublets associating with each other and forming bends w
65 , composed of three bands: one low intensity doublet at 440 and 455 nm; one strong band at 525 nm; an
68 identity of >99% of singlets and identifies doublets at rates consistent with previous estimates.
72 topic labeling products appearing as M/M + 2 doublets can be directly identified using the program Do
74 d at high levels, extra spikes (for example, doublets) can occur in response to a single light pulse,
75 ks at 737 and 754 cm(-1) assigned as a Fermi doublet centered at 746 cm(-1)(Delta(18)O = 31 cm(-1)).
76 lene; it should proceed for the ground state doublet CH through C2h-like trajectories, with no activa
77 (35 cycles) or investigator-choice platinum-doublet chemotherapy (4-6 cycles or until documented dis
79 ival in patients who received platinum-based doublet chemotherapy as subsequent line of treatment.
80 ll patients also received the platinum-based doublet chemotherapy cisplatin 75 mg/m(2) plus pemetrexe
81 er the addition of pembrolizumab to platinum-doublet chemotherapy improves efficacy in patients with
82 o show that adding a third agent to platinum-doublet chemotherapy improves efficacy in the first-line
85 ad progressed during or after platinum-based doublet chemotherapy to receive nivolumab at a dose of 3
88 nsidered cost-effective when compared to the doublet cisplatin-5-fluorouracil from the British and It
89 alyzed by ESI-MS all fatty acids appeared as doublet clusters of ions separated by roughly 3 amu.
90 emsirolimus, and bevacizumab administered in doublet combinations did not significantly improve media
91 ess toxicity and efficacy of cisplatin (Cis) doublet combinations in advanced and recurrent cervical
93 entified by routine flow cytometry represent doublets comprised of Foxp3(-) DP and Foxp3(+) CD4(+)CD8
95 ra integrating a monolithic metasurface lens doublet corrected for monochromatic aberrations, and an
96 In the ASD group, the presence of lactate doublets correlated significantly with age (P = .004) an
97 anthanide SMM in which all low-lying Kramers doublets correspond to a well-defined MJ value, with no
98 ass spectral peaks to single data points), 9 doublets corresponding to APAP metabolites were identifi
99 ers but also higher-order statistics such as doublet counts, triplet counts, and, in general, k-let c
102 aired electron on (2)BPNO(*) to form excited doublet (D(1)) and quartet (Q) states, which are both sp
103 ts on the conical intersection of the ground doublet D0 and first excited doublet D1 states are found
104 n of the ground doublet D0 and first excited doublet D1 states are found to be in close geometric and
105 also exhibited an intense central quadrupole doublet due to S = 0 [Fe(4)S(4)](2+) clusters and low-sp
106 of endoreplication and that PNCs split into doublets during mid S phase, both of which are phenotype
108 2d,p) potential energy surface of the ground doublet electronic state of the peptide radicals provide
109 sine mutants of KatG exhibit the same narrow doublet EPR signal and catalase activity similar to that
110 technical noise and minimizes unwanted cell doublet events in mass cytometry data, and it reduces we
111 thways for the Q(1) --> D(0) decay involving doublet excited states were also evaluated and found to
113 whereas the other four appear as two sets of doublets following cleavage through an elastase-like enz
114 the basis of CGA (CGA arm: carboplatin-based doublet for fit patients, docetaxel for vulnerable patie
116 3 helps generate a high-affinity site on the doublets for outer arm assembly, either through direct i
118 so informative are NCG-GNN and NCC-GNN codon doublets, for which an unusually high rate of G to C and
120 uter junction, crucial for the initiation of doublet formation, appears to be formed by close interac
122 s and mitochondria contained a low-intensity doublet from non-heme high-spin (NHHS) Fe(II) species.
123 The ureteric buds (UBs) in mutants emerge as doublets from the intermediate mesoderm (IM)-derived nep
125 inical benefit to the rituximab-lenalidomide doublet, further investigation of the regimen in this se
126 m-based I(X 1; X 2; Y) (mutual information), doublets (gene pairs) and MIC(X 1; X 2; Y) based on the
128 3] in an organic glass has a spin-frustrated doublet ground state and a thermally accessible quartet
129 riplet, while the quinoniminyl radical has a doublet ground state with a doublet-quartet splitting of
131 earches at the B3LYP level yield triplet and doublet ground states for the oxygen-rich neutral and an
134 1) in unprecedented detail, with full Lambda-doublet (hence total NO parity) resolution in both the i
135 monophosphonated TAM probe with the simplest doublet hfs pattern ideally suited for dual function ele
136 PS and age (standard arm: carboplatin-based doublet if PS </= 1 and age </= 75 years; docetaxel if P
138 appeared by SDS-PAGE analysis as a 35/40-kDa doublet in all cells, variations occurred in the relativ
141 ork including a strong correlation in the EG doublet in motif 1 of family 4 UDGa and in the QD double
142 suggest that the correlated mutations in the doublet in motif 1 position the catalytic H155 in motif
144 well as higher energy first excited Kramers doublets in 4 and 6 leading to higher energy barriers fo
148 drc-mutant axonemes resulted in splaying of doublets in the distal region, followed by oscillatory b
150 in family 4 Thermus thermophilus UDGa to QD doublet increases the catalytic efficiency by over one h
153 reconstructions revealed that no particular doublet initiated the symmetry break, and moreover it of
154 tructure of motile axonemes contains nine MT doublets interconnected by nexin links, which surround a
156 by the incursion of one or more microtubule doublets into the axoneme core, giving rise to an archit
159 demonstrate that the larger isoform of each doublet is the result of phosphorylation at a key degrad
163 ear observed preference for OD Pi(A') Lambda-doublet levels is not consistent with a simple extrapola
164 mplex, and emission occurs from a long-lived doublet ligand-to-metal charge-transfer ((2)LMCT) state
168 a tether linking one I1 motor domain to the doublet microtubule and doublet-specific differences pot
172 sists of a 9-fold array of remarkably stable doublet microtubules (DMTs), along which motor proteins
178 and B-tubule singlets from nine ciliary A-B doublet microtubules in cephalic male (CEM) neurons.
179 2 genes in the pathway mediating assembly of doublet microtubules in the axoneme from triplet microtu
180 FAP50 is tightly associated with the outer doublet microtubules of the axoneme and appears not to b
181 flagella have a conserved structure of nine doublet microtubules surrounding a central pair of micro
183 in the transition of triplet microtubules to doublet microtubules, a defect correlated with failure t
184 d spoke bases that facilitate docking to the doublet microtubules, and that inner dyneins connect dir
185 lutamylation mainly on the B-tubule of outer doublet microtubules, the site of force production by ci
186 le distinguishing each one of the nine outer doublet microtubules, we systematically collected and re
187 ar transport, and bound to specific sites on doublet microtubules, where their activity facilitates m
192 Additional treatment with CO altered the doublet Mossbauer parameters, suggesting an interaction
193 th d-wave pairing in a Majorana type Kramers Doublet (MTKD) state, it is important to lift both the s
196 MR features of the RPA derivatives include a doublet near 4 ppm in their (1)H NMR spectra and a tripl
197 a localizes strictly to a proximal region of doublet number 1, which completely lacks ODAs in Chlamyd
198 mal axonemal structures with loss of tubulin doublets occur in most Stamp(tm/tm) sperm tails in conju
199 l domain of the L-selectin tail as well as a doublet of aspartic acid residues ((369)DD(370)) in the
200 difficulty is seen in the preference for the doublet of the parent SiH (doublet-quartet energy differ
204 representation of phosphorylated peptides as doublets or triplets according to the number of phosphat
205 imilar preferred directions tend to occur in doublets or triplets, and (iii) such minicolumns tend to
207 nals connected to cones with single boutons, doublets, or rosettes, whereas the rod HCs connected to
210 ously observed by Aoyama and Kamiya in outer doublet pairs obtained after partial dissociation of Chl
212 of these reagents provides a characteristic doublet pattern of DMDSSO cross-linked peptides, thus ai
214 It accounts for the experimental Lambda-doublet populations via explicit consideration of the st
217 rigin is quantum coherence between the lower doublet produced by the pump and probe fields, similar t
218 itio calculations predict specific NO Lambda doublet propensities (orientations of the unpaired elect
220 ry, the ground state of dysprosium(III) is a doublet quantized along the anisotropy axis with an angu
221 arbynes (silylynes) examined, whose range of doublet-quartet differences calculated is impressive, 12
222 reference for the doublet of the parent SiH (doublet-quartet energy difference approximately 39 kcal/
224 e singlet (WS) radical, rather than the wide doublet radical observed with PGHS-1 reconstituted with
226 and under both of these conditions, a narrow doublet radical signal with an 11 G principal hyperfine
227 we present a method to calculate the Lambda-doublet ratio when concurrent potential energy surfaces
228 CPR were not superior to the alkylator-free doublet Rd, which was associated with lower toxicity.
230 f dynein-driven sliding, doublet separation, doublet reassociation, and resumption of sliding was pre
234 r use of any chemotherapy and platinum-based doublet regimens with increasing age, comorbidity, and p
236 ssbauer spectra consisting of two quadrupole doublets representing 51% and 21% of the Fe, with parame
238 of the in vitro binding of ODAs to axonemal doublets reveal a role for the ODA5/ODA10 assembly compl
239 a 15 aa domain containing an arginine-lysine doublet (RK peptide) within Otx2, bearing prototypic tra
241 ata for 2 reveals that an excited state spin doublet (S(T) = (1)/(2)) is populated at higher temperat
243 s oscillation by inactivation of dynein when doublets separate and resumption of dynein activity afte
245 hin the MS spectrum owing to the presence of doublets separated by 6.01 Da; representing versions of
246 A regular cycle of dynein-driven sliding, doublet separation, doublet reassociation, and resumptio
247 ur distinct song types were identified: long doublet, short doublet, long triplet, and short triplet.
249 two samples is proportional to the ratios of doublet signals with a static 6 Da mass difference in MA
250 duration and 1.37 ps separation; and singlet+doublet soliton structures with 1.8 ps duration and 6 ps
251 motor domain to the doublet microtubule and doublet-specific differences potentially contributing to
252 n dimension allows direct measurement of the doublet splitting to extract 1JCalphaC' scalar and 1DCal
255 gel electrophoresis and blotting, a chain of doublet spots at 65 kDa was detected by anti-AgALP.
257 mputational work suggested that the low-spin doublet state D(0) of the Ni(III)-d(7) system is signifi
260 ver the OD(X(2)Pi) fine-structure and Lambda-doublet states, diagnostic of electronic non-adiabaticit
261 own a clear preference for the Pi(A') Lambda-doublet states, in apparent contradiction with ab initio
264 of orbital-nematic ordering of a non-Kramers doublet that an orthogonal strain or a perpendicular mag
265 er studies of NfuA showed a broad quadrupole doublet that confirmed the presence of [4Fe-4S]2+ cluste
266 initiate the formation of tightly associated doublets that are present at high frequency in adult Per
267 protein molecules arrayed along microtubule doublets that span the length of axoneme (the flagellar
268 subunit Cdc11 or the normally central Cdc10 doublet, the combination of the PIP2-containing monolaye
269 riority of nonplatinum therapy over platinum doublet therapy for ERCC1-positive NSCLC as well as noni
270 s in the first-line setting include platinum-doublet therapy for those with PS 0 to 1 (bevacizumab ma
271 therapy was four or more cycles of platinum doublet therapy or 3 or more months of EGFR or ALK inhib
272 (15 mg/kg) every 3 weeks with platinum-based doublet therapy or erlotinib (at physician's decision),
273 nt and survival benefit from use of platinum-doublet therapy, and addressing the role of performance
275 ng the easy magnetization axis of the ground doublet; this value is significantly larger than the spi
276 involves at least the fourth-excited Kramers doublet, thus demonstrating that prominent SMM behavior
277 agnetic axiality, even in the fourth Kramers doublet, thus demonstrating the potential of rigid diami
278 deuterated tyrosine causes a collapse of the doublet to a singlet, while for 3,5-ring-deuterated tyro
279 g combinatorial barcoding scheme allows cell doublets to be identified and removed from the analysis.
282 ailable literature for active single agents, doublets, triplets, and multiple drug combination chemot
283 ior muscles and changed in its morphology to doublets, triplets, and multiplets in the first dorsal i
287 In contrast to teleseismic analysis of this doublet, we use regional seismic data providing robust t
288 th clear signs of advanced rediploidization, doublets were diploidized with ancestral tetraploidy alr
291 two systemic regimens, including a platinum doublet, were randomly assigned at a 1:1 ratio to receiv
292 r singlet microtubules are converted into BB doublets which subsequently grow asynchronously to templ
293 activity causes relative sliding between the doublets, which generates propulsive bending of the flag
295 line of Gd(2)@C(79)N is due to the Kramer's doublet with a half-integer spin quantum number of S = 1
296 ssbauer spectrum of 2b exhibits a quadrupole doublet with delta = -0.04(1) mm.s(-1) and DeltaE(Q) = 2
297 PR-silent intermediate exhibits a quadrupole doublet with delta = 0.58 mm/s and DeltaE(Q) = 0.58 mm/s
299 These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskeletal str
300 transient tyrosyl-like radical with a narrow doublet X-band EPR signal is present during catalase tur
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