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2 solid-state characterization, of (17)O- and doubly (17)O- and (29)Si-enriched UTL-derived zeolites,
3 7+) --> [Nb2](6+) + [Nb2](8+)), resulting in doubly (2.5000(9) A) and singly bonded (2.6560(9) A) Nb2
5 lts from molecular dynamics simulations of a doubly acetylated histone H4 peptide bound to the bromod
6 hat the bulkiness and the reactivity of this doubly activated intermediate III control the selectivit
7 classes of AdoMet analogues currently exist: doubly-activated molecules and aziridine based molecules
8 nsition state, facilitating proton transfer, doubly activating the substrate for reaction, and perhap
10 re consistent with a quasilinear, nonplanar, doubly allylic structure of X(3B) HCCCH with both diradi
11 avoid common drug resistance mechanisms with doubly amphiphilic poly(2-oxazoline)s (POx), a safe and
17 a central barbiturate motif and an optimized doubly anthracene-terminated acyclic Hamilton-like recep
18 (3-) ligand is found to be highly stable and doubly aromatic with six delocalized pi and six delocali
24 ore stable than the dimeric structure with a doubly bridged motif [Zr(IV)(2)(mu-O(t)Bu)(2)] where the
25 Reported herein is an enantiomeric pair of doubly-bridged naphthalene-1,8:4,5-bis(dicarboximide) (N
26 esis and application of a practically useful doubly caged GABA analog, termed bis-alpha-carboxy-2-nit
28 tructure, bonding, and relative stability of doubly charged alkane dications and monocharged boron ca
30 AIMS conditions selected for transmission of doubly charged cardiolipins (CL), for example, detection
31 elds exerted by other cations, in particular doubly charged cations like Mg(2+)aq and Ca(2+)aq, induc
34 th sequences to 83% of the spectral pairs of doubly charged ions with high-confidence database identi
39 ively dissociate the singly charged dimer or doubly charged monomer of the peptide gramicidin A and c
40 nformations is presented here for gas-phase, doubly charged peptides of sequence XAnK, wherein X is D
42 e calculated rate for the outward release of doubly charged Pi from the alphabetaE interface 120 degr
45 ine serum albumin, providing ECD spectra for doubly charged precursor ions with very good efficiency.
46 70,000 resolution on the product ions of the doubly charged precursor of the target peptide ((24)TWCD
50 ion intensities in the mass spectra of this doubly charged tryptic peptide, based solely on its amin
54 yons (Lambdac) undergo fusion to produce the doubly charmed baryon and a neutron n (), resulting in a
58 between the dynamics measured in singly and doubly CN-labeled HP35, demonstrating that the presence
60 oded dimples" on the surface of surface-core doubly cross-linked micelles, we synthesized water-solub
63 A series of three Pt(II) complexes with a doubly cyclometalating terdentate ligand L1, L1H2 = 3,6-
65 dimers and tetramers became both singly and doubly decorated by sigma-1 receptors; however, hERG mon
69 eficient, polypeptide binding-deficient, and doubly deficient calreticulin constructs in calreticulin
70 unx2, but not Runx1 or Runx3, in Smad2/Smad3 doubly deficient CD4 cells restored selectin ligand expr
71 icient MEFs, but had no additional effect on doubly deficient cells, suggesting that NONO/PSPC1 and D
74 show that mice reconstituted with a Bak/Bax doubly deficient hematopoietic compartment develop a fat
79 eficient mice, autophagy-deficient mice, and doubly deficient mice suggested that defective autophagy
81 her molecule; this effect was accentuated in doubly deficient recipients, with a 40-fold increase com
86 )E ground state (idealized C3 symmetry) with doubly degenerate frontier orbitals, (e)(3) = [|mL +/- 2
89 t reactivities upon gas-phase reactions with doubly deprotonated 1,4-phenylenedipropionic acid (PDPA)
90 s is demonstrated via ion/ion reactions with doubly deprotonated 1,4-phenylenedipropionic acid (PDPA)
91 ave been subjected to ion/ion reactions with doubly deprotonated 4-formyl-1,3-benzenedisulfonic acid
93 transfer to the two carboxylate moieties in doubly deprotonated PDPA to yield [PE - H](-) anions.
95 erified experimentally by the observation of doubly deuterated acetic acid (CH2DCOOD), when D2O is in
97 amma-amino-alpha,beta-unsaturated ester, and doubly diastereoselective conjugate addition of the anti
98 ic and nuclear dynamics in the bound states, doubly differential yields (differential in both electro
100 ults demonstrate that linguistic preferences doubly dissociate from sensorimotor demands: A single st
102 otivational influences on choice that can be doubly dissociated both neuroanatomically and neurochemi
104 ediated gene editing and the construction of doubly DNA-tethered proteins for single-molecule studies
105 maxima at x=0.15 and 0.20 for the singly and doubly doped ceria, respectively, suggesting that the nu
111 n-photon correlations of systems prepared in doubly excited W-states and give conditions when the ato
119 In their native form, most Rab GTPases are doubly geranylgeranylated at the C terminus to achieve l
120 e primarily to their childhood exposure to a doubly heterosubtypic putative H3N8 virus, which we esti
122 lly in a transactivation assay and that mice doubly heterozygous for loss-of-function mutations in Tc
123 mentation in vivo in Themis(I23N/+):Lck(-/+) doubly heterozygous mice demonstrate that functional cou
125 between jal and a Gata3 null allele produced doubly heterozygous, phenotypically mutant offspring.
127 ally expressed in Vangl2(Lp/Lp) embryos, and doubly homozygous Vangl1/Vangl2 mutants exhibited normal
128 mer has a lower energy than the alternative, doubly hydrated trans tautomer by some 8.3 kcal mol(-1)
129 d not affect the heart size of Flcn/Ppargc1a doubly inactivated hearts, further supporting the idea t
132 ith mechanical bonding, in isomeric [3]- and doubly interlocked [2]catenanes controls the formation o
133 try, and X-ray crystallography confirmed the doubly interlocked topology, and subsequent demetalation
134 havior intrinsic to Zn(CN)2 is observed; the doubly interpenetrated diamondoid framework structure tr
136 tuation is to be contrasted with that of the doubly interpenetrated oligophenylene analogue, NOTT-104
137 ,8-Dihydroxy-2-naphthaldehyde (DHNA), having doubly intramolecular hydrogen bonds, was strategically
139 l neutral and ionic H-bonds it is clear that doubly ionic H-bonds cover the full range of weak throug
142 Using this range of parameters and comparing doubly ionic H-bonds to more traditional neutral and ion
145 e that natural isotope containing (SmB6) and doubly isotope enriched ((154)Sm(11)B6) crystals prepare
146 he kinetic isotope effect (KIE) observed for doubly labeled AB (k(NH3BH3)/k(ND3BD3) = 3.7) is the pro
149 on-electron resonance (DEER) measurements on doubly labeled constructs of CBD12 have shown that the b
150 py (FCS) system to measure the percentage of doubly labeled dsDNA (PDL) in the total fluorescent dsDN
151 curate measurement of the percentage of such doubly labeled dsDNA component is a critical prerequisit
152 in that is bound to DNA origami; 2), a minor doubly labeled dsDNA subpopulation concealed in a larger
153 In a glassy trehalose matrix the Tm for the doubly labeled T4 lysozyme was long enough to measure an
155 repeated measures of energy expenditure via doubly labeled water (DLW) along with multiple dual-ener
156 ture (TEE) in patients with SBS by using the doubly labeled water (DLW) method to inform energy needs
158 ergy expenditure (TEE) measured by using the doubly labeled water (DLW) method; however, the database
159 ta, Canada (2009-2011), who completed 14-day doubly labeled water (DLW) protocols, 7-day activity dia
162 ming a classical measurement error model for doubly labeled water and a Berkson error model for the e
163 expenditure measured over 10 days at home by doubly labeled water and for 36 hours in the laboratory
168 culated as the total energy expenditure from doubly labeled water minus the resting energy expenditur
169 ine energy requirements were determined by a doubly labeled water study and caloric titration to weig
170 tion level, and estimated energy intake from doubly labeled water) were used for evaluation against e
171 red total energy expenditure, measured using doubly labeled water, against physical activity, measure
172 energy expenditure were also available from doubly labeled water, and basal energy expenditure was e
174 ctivity-related energy expenditure (AREE) by doubly labeled water; and dietary protein intake by self
175 single-stranded oligonucleotide probes were doubly labeled with adjacent thiazole orange derivatives
177 and it is even difficult to distinguish the doubly-labeled DNA component from the singly-labeled com
178 nsufficient to measure the percentage of the doubly-labeled dsDNA component in the fluorescent DNA sa
179 The methodology was evaluated using seven doubly-labeled mutants of myoglobin designed to monitor
181 ntly measured field metabolic rates with the doubly-labelled water method and derived activity-specif
182 xperiments to understand the contribution of doubly light chain mispaired bispecific IgG was demonstr
183 crocycle composed of six glycoluril residues doubly linked through their nitrogen atoms to each other
185 e eligible to enter an adaptively allocated, doubly masked, placebo-controlled trial using a continuo
187 at the carbon source utilization by rne deaD doubly mutant bacteria differs from that of rne(+) cells
191 d that some may be initiated or sustained by doubly mutated immune cells that have both inappropriate
193 acrocycle transformations to give singly and doubly N-CAr -fused N-confused corroles, L3 and L4, resp
199 iguration interaction calculations, close to doubly occupied configuration interaction calculations.
200 bridge moiety via the spin polarization of a doubly occupied orbital with phenylene bridge character.
201 are observed as resonances in the number of doubly occupied sites when the tilt per site is tuned to
202 elopment of HLH, we generated mice that were doubly or triply heterozygous for mutations in HLH-assoc
204 +), and singly oxidized [2Cu2](+) as well as doubly oxidized [2Cu2](2+) were characterized in detail
205 specific emphasis on the manifestation of a doubly oxidized Co(IV)2 center on O-O bond formation.
208 et biradical (polaron-pair) character in the doubly oxidized ground state: the open-shell singlet (S2
211 rmation products corresponding to singly and doubly oxygenated forms of 6:2 FtTAoS were also identifi
213 states of PLB (U-PLB, P16-PLB, P17-PLB, and doubly phosphorylated 2P-PLB) have not been measured qua
214 We investigated the binding of singly or doubly phosphorylated and thiophosphorylated peptides, c
216 that the 14-3-3? dimer and the S19- and S40-doubly phosphorylated peptide interact in multiple ways,
218 tions of PRD histidines, we establish that a doubly phosphorylated PRD1 phosphomimetic (D/DMga4) is c
220 l signaling context, preventing formation of doubly phosphorylated STAT3 by depleting GSK-3alpha/beta
221 studies on the unphosphorylated, singly, and doubly phosphorylated variants of Mengovirus L (L(M)) sh
222 2 + 2] cycloaddition reaction is the singlet doubly pi(2)pi*(2) excited state, which is spectroscopic
226 e] </= 1/2 [TFA] the substrates exist in the doubly protonated form HR2N(+)(CH2)nN(+)R2H, and no reac
227 ecies as [(TPB)Fe identical withN-NH2](+), a doubly protonated hydrazido(2-) complex featuring an Fe-
228 he Ni(II) complex gives three isomers of the doubly protonated Ni(0) complex [Ni(P(Cy)2N(t-Bu)2H)2](B
229 Further reduction of the pH results in the doubly protonated species with a high electron-deficienc
231 His(37) and Trp(41) sites in the singly and doubly protonated states, but it opens at Trp(41) upon f
235 llumination, and photolysis can also produce doubly reduced 1,4,5,6-tetrahydro-1-methylnicotinamide.
238 Box(4+)) to form both the ExBox(3+*) and the doubly reduced ExBox(2(+*)) states from a single laser p
240 pecifically that both the singly reduced and doubly reduced Mn complexes form at the same potential.
241 lectron rich Ni(I)-Ni(I) bond supported by a doubly reduced naphthyridine-diimine (NDI) ligand reacts
242 , yielding N2 bound to FeMo-cofactor that is doubly reduced relative to the resting redox level, and
243 y, a catalyst-controlled direct formation of doubly reduced silyl ethers is presented, specifically v
245 on is second order in the density of active, doubly reduced species independent of whether these are
247 lower the potential necessary to access the doubly reduced states of these manganese catalysts by el
250 w how roughness alone, if made of a specific doubly reentrant structure that enables very low liquid-
251 isk (CSD) microscope can be converted into a doubly resolving image scanning microscopy (ISM) system
257 iterature by presenting a simple closed-form doubly robust estimator of the adjusted odds ratio for a
260 or using inverse probability weighting and 2 doubly robust estimators in a variety of scenarios.
261 Tchetgen et al. recently developed so-called doubly robust estimators of an adjusted odds ratio by ca
262 odels, the structural transformation method, doubly robust g-estimation of a structural nested model,
264 aximum likelihood based estimation (TMLE), a doubly robust method that can be coupled with machine le
266 estimation of a structural nested model, and doubly robust targeted minimum loss-based estimation.
267 ore dramatic phenotypes were obtained in the doubly silenced flowers, where all stamens and staminodi
269 increases in signal-to-noise ratios for the doubly sodiated steroid metabolites in unspiked urine (>
273 sh that a chiral nickel catalyst can mediate doubly stereoconvergent alkyl-alkyl cross-coupling, spec
276 lasers for MALDI, we systematically compared doubly substituted alpha-cyanocinnamic acid derivatives
279 upported by further experiments in which the doubly tagged construct was cotransfectionally diluted w
281 of solution and gas phase measurements on a doubly tagged tripeptide shows that dimer-induced fluore
287 ansgenic T cells, we generated Ptpn22/BDC2.5 doubly transgenic mice and found reduced proliferation a
288 carcinoma was significantly increased in the doubly transgenic mice expressing both LMP1 and LMP2A.
290 ng a phyB null mutant background, singly and doubly transgenic plants were generated that express fus
291 We report synthesis and investigation of doubly trimethylene-bridged tetrabenzyl-p-phenylenediami
294 on from a deformation-free ground state to a doubly twisted structure, and results in spontaneous sym
298 Triply resonant sum frequency (TRSF) and doubly vibrationally enhanced (DOVE) spectroscopies are
299 s(2,6-di-2-naphthylphenoxide) (ATNP), in the doubly vinylogous aldol reaction between methyl-5-methyl
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