ライフサイエンスコーパス: doubt

1 h no difference in subjective confidence (or doubt).

2 nt research that brings this assumption into doubt.

3 al power has cast neuroscience findings into doubt.

4 cy of risk adjustment in those studies is in doubt.

5 e between experimental treatments is open to doubt.

6 t their lack of toxicity in humans is not in doubt.

7 me periods, calling the former paradigm into doubt.

8 plausibility of these various hypotheses in doubt.

9 e need for confirmation of diagnosis when in doubt.

10 efficient neurotransmission has remained in doubt.

11 ill in question but whose effects are beyond doubt.

12 hanism compared with full fusion is still in doubt.

13 a diverse set of human cancers is now beyond doubt.

14 mericans before admixture is also subject to doubt.

15 flicting results in recent years have raised doubts.

16 d risks of immunization may counteract these doubts.

17 yndrome (MFS) and BBE in cases of diagnostic doubts.

18 bodies used to identify P2X7R raised further doubts.

19 arpa, 2012) in which graphene is without any doubt a forefront nanomaterial.

20 nosis of juvenile dermatomyositis (DM) is in doubt, a case has not been made for routine muscle biops

21 ), the American public expresses substantial doubt about both the anthropogenic cause and the level o

22 rall, 88% (44 of 50) of surrogates expressed doubt about physicians' ability to prognosticate for cri

23 If there is doubt about safety, the question arises of whether patie

24 his eligibility for organ donation and cast doubt about the ability to determine irreversibility of

25 h many surrogate decision-makers harbor some doubt about the accuracy of physicians' prognostications

26 nal connectivity studies on prosody leave no doubt about the existence of such streams, but opinions

27 data obtained from rodent models and raises doubt about the justification of resveratrol as a human

28 dinary success of Wikipedia there remains no doubt about the potential of collaborative publishing, y

29 abnormality and seem to remain stable, with doubt about the presence of underlying neurodegenerative

30 New work has raised some doubt about the protective effect of colonoscopy in the

31 lly interpreted as negative, thereby raising doubts about a potential causal association.

32 ust in the determination of death; and raise doubts about fair allocation of organs.

33 rminal gametogenesis remains inefficient and doubts about gamete function persist.

34 Doubts about its clinical impact exist, however, because

35 of many others currently being used, raises doubts about its effectiveness and benefits (along with

36 strated in human red blood cells (RBCs), but doubts about its functional significance, isoform identi

37 epistasis is ubiquitous, and this has led to doubts about its importance in biological evolution.

38 s, and the ubiquitous nature of the USF cast doubts about its role.

39 ts targeting this protein has raised serious doubts about its therapeutic utility.

40 Opinion article, Brienen et al. (2016) raise doubts about our finding that tropical tree growth has n

41 itive to sensory-behavioral variables raises doubts about previous experiments that purport to show w

42 Surrogates' doubts about prognostic accuracy did not prevent them fr

43 ct themes emerged that explained surrogates' doubts about prognostic accuracy: a belief that God coul

44 s of cartilage damage in dogs, raise serious doubts about selective thyroid hormone mimetics as a the

45 Recent studies have raised doubts about that view but have uncovered crucial roles

46 Recent research has raised doubts about the efficacy of calcium supplementation in

47 Guala's doubts about the evidential support for this hypothesis

48 emporal lobe structures for memory and raise doubts about the idea that these structures have a promi

49 This finding raised important doubts about the interspecies translatability of PPARgam

50 lations investigated in a recent study raise doubts about the nutritional adequacy of high TFA intake

51 ed exposure of the brain to insulin, raising doubts about the overall physiological relevance of insu

52 ansfusions rather than by the graft, casting doubts about the possible role of antibodies in a patien

53 2 (VGluT2) mRNA in Ipc neurons, have raised doubts about the purely cholinergic nature of this nucle

54 Recent studies have raised serious doubts about the role of antibiotic prophylaxis after UT

55 ial carcinoma samples were HPV38(+), raising doubts about the significance of the HPV38 association.

56 g of currently published case reports raises doubts about the value of many of them but also emphasiz

57 an temperature is not reliable, thus raising doubts about their conclusions.

58 frequency and membrane conductance, raising doubts about their effectiveness in the awake behaving b

59 es of the zeolite structures considered cast doubts about their real-world applicability.

60 nant properties of metamaterials have raised doubts about their usefulness.

61 -SSIM) also develop severe progeria, raising doubts about whether any treatment targeting protein pre

62 d other structural peculiarities have raised doubts about whether bNOSs were capable of producing NO

63 tion-transporting P-type transporters raised doubts about whether P(4)-ATPases alone are sufficient t

64 Doubts about whether UCB, containing 10-20x fewer cells

65 underpinning scientific disciplines will no doubt accelerate the transfer of polymer therapeutics in

66 In those early days, there was great doubt and skepticism about the utility of UCB as a sourc

67 e LV dysfunction in mitral regurgitation are doubted and poorly followed in clinical practice.

68 loved one, 5) continuity and closure, and 6) doubts and ambivalence.

69 should allow them to voice and discuss their doubts and prepare them for the peculiarities of caring

70 thnic groups was ambivalence about donation: doubts and worries, feeling unsure about donation, wishi

71 Although subsequent work has raised some doubt as to whether ribotype 027 strains are hypervirule

72 ly, the architecture of Hensen's node raises doubts as to whether Ca(i)(2+) asymmetry is a broadly co

73 T(c) superconductivity, however, has been in doubt because so far it has been found only in hole-dope

74 ve for the free acid ibuprofen substrate, no doubt because this substrate can compete with the inhibi

75 One widely-accepted model, called into doubt by recent findings, is the maskin hypothesis for t

76 "The beginning of wisdom is found in doubting; by doubting we come to question, and by seekin

77 articipants with more severe symptoms in the doubt/checking dimension.

78 of activation was inversely associated with doubt/checking symptoms.

79 This study aimed to address these remaining doubts concerning auditory cortical alpha.

80 typing studies; the list of variants will no doubt continue to expand at a rapid rate as genotyping t

81 graphy in the tissue environment and will no doubt continue to provide greater understanding of cellu

82 en serum titers and brain pathology have, no doubt, contributed to a delayed appreciation of the cont

83 ces for the field, including the strategy of doubt creation and the recruitment of epidemiologists by

84 confronted by organized campaigns to spread doubt, denial, and rejection of the scientific community

85 gest disagreement was between benefit-of-the-doubt-derived and principal-component-analysis-derived w

86 There is little doubt evolution has played a major role in preventing th

87 Three new studies will no doubt facilitate this transition by generating the C2c1

88 systemic treatment of recurrence are now in doubt following the presentation of the MRC/EORTC CA125

89 veness has been experimentally proven beyond doubt for the specific type of surgery being considered,

90 After raising some doubts for cultural group selection as an explanation of

91 Without doubt, GFP and spectral derivatives have revolutionized

92 Recently some doubt has arisen concerning the applicability of graphle

93 However, doubt has been drawn on the ubiquity of the mechanism by

94 rstanding of pharmacoresistance, because (1) doubts have been raised about their reproducibility, (2)

95 roscopic donor nephrectomy [LDN]) in adults, doubts have persisted about its use in pediatric recipie

96 n be rescued by treatment with exogenous NO, doubts have recently been raised as to whether AtNOS1 is

97 We doubt, however, that those recommendations go far enough

98 Dendritic cells (DCs) are without a doubt important key skin cells that connect information

99 of vaccination was correlated with patients' doubt in the efficacy of the vaccine.

100 all 22 cases of Leu/Ile residues, leaving no doubts in identification.

101 Such abilities are no doubt key to successful communication in many taxa, but

102 We suspected that those doubts might be premature and hypothesized that the pers

103 Respondents with feelings of guilt doubted more about direct contact.

104 ity that muscle mitochondrial mechanisms, no doubt multifactorial, may be important in deterioration

105 On the other hand, he doubts my assertion that the confinement entropy is alre

106 roduction from innate immune cells, but cast doubt on a different study, which suggests that this miR

107 ranscription factors are infrequent, casting doubt on a direct role for E2Fs in driving cancer.

108 cy, detectable regulatory polymorphisms cast doubt on a model in which cis-acting variation is a prod

109 These problems with the data presented cast doubt on all the data, and accordingly also the conclusi

110 The problems with the data presented cast doubt on all the data, and accordingly also the conclusi

111 However, recent evidence has cast doubt on both these associations, tempering hopes of the

112 pressure vary with setting, thereby casting doubt on causality.

113 These results cast doubt on certain experimental methods and demonstrate th

114 efficacy data with drug leads, leaving some doubt on clinical translation.

115 ng abstract shapes, a conclusion which casts doubt on cognitive explanations of fly behaviour in patt

116 This finding casts doubt on earlier assumptions that PI provides directiona

117 al regurgitation in cardiomyopathy and casts doubt on FMR being purely "functional" in etiology.

118 difficulties inherent in such controls cast doubt on how effective miRNAs are in driving phenotypic

119 ertrophic or dilated cardiomyopathy, casting doubt on its acceptance as a distinct disease entity.

120 erythromelalgia, supporting recently raised doubt on its causal nature.

121 l amphi-North Atlantic distribution, casting doubt on its non-native status in the NW Atlantic.

122 c cases, and also found in controls, casting doubt on its pathogenicity.

123 Mc+) has never been established, which casts doubt on its role in leukemogenesis.

124 r prostate cancer, further studies have cast doubt on its utility to diagnose this condition.

125 arge collaborative outcome studies have cast doubt on many traditional 'common sense' practices.

126 The combined results cast doubt on previous reports describing MOF-5 as a semicond

127 by phenyl to naphthyl substitution, casting doubt on previous reports of predicted binding orientati

128 This casts serious doubt on projections that rising [CO2] will fully offset

129 e localisation techniques, therefore casting doubt on reported differences in brain generators.

130 hrenia was not observed, which casts further doubt on schizoaffective diagnosis.

131 e acceleration with age, and would cast some doubt on stage-number inferences from multistage carcino

132 ated with shear thinning and thickening cast doubt on that conclusion and leave unsettled whether the

133 research on spontaneous transformation cast doubt on that interpretation, and motivated re-examinati

134 aps in our knowledge seem to cast additional doubt on the ability of the field to move forward effect

135 o such expansion in the simulations, casting doubt on the accuracy of methods that infer demography f

136 es are of malignant origin, our results cast doubt on the assumption that adherent tumor-derived cult

137 Recent studies have cast doubt on the benefit of cardiac resynchronization therap

138 ts from a large multi-center study have cast doubt on the benefit of the broad application of hypothe

139 ctional consequences of their mutations cast doubt on the causal role of NL4 mutations in these disor

140 At the same time, they cast doubt on the classical linkage of semantic error product

141 f viral mutagens has been difficult, casting doubt on the clinical viability of this strategy.

142 ized left ventricular ejection fraction cast doubt on the complete reversibility of this condition.

143 ered to be important for those models, casts doubt on the current hypothesised mechanisms of exclusiv

144 In Ghana, a recent report also cast doubt on the current mechanism of delivering free care--

145 Our analysis thus casts doubt on the degree to which quantum discord is necessar

146 ravel advice on malaria prevention, but cast doubt on the effectiveness of current strategies to prev

147 Our results cast doubt on the existence of a Kauzmann entropy catastrophe

148 This result casts strong doubt on the existence of a poneroid clade as currently

149 ption creates an obvious confound that casts doubt on the feasibility of first-spike latency codes.

150 r can be retrieved associatively and casting doubt on the general consolidation hypothesis.

151 te short-term glucose homeostasis, but casts doubt on the general usefulness of the inhibition of IDE

152 ells with tumorigenic potential casting some doubt on the hypothesis of hierarchical or differentiati

153 This work casts doubt on the hypothesis that localized tissue modulation

154 distal environmental factors, then they cast doubt on the hypothesis that such factors have large eff

155 These results cast doubt on the hypothesis that the greenish warbler should

156 unohistochemistry hypoxia markers casts some doubt on the hypoxia selectivity of (64)Cu-ATSM.

157 ired for meiosis in the genome has also cast doubt on the idea that Giardia is primitively asexual, b

158 gle-crystal absorbance measurements, casting doubt on the idea that ground state conformational heter

159 Thus our results cast doubt on the idea that mammalian proteasomes cannot degr

160 recent findings by several groups have cast doubt on the importance of canonical disulfide pairing t

161 This observation has cast doubt on the importance of disk-driven migration as a me

162 Recent studies in murine models have cast doubt on the importance of JAK2 in CML maintenance.

163 24 h beyond a single exercise bout, casting doubt on the importance of nutrient timing vs. sufficien

164 In addition, our study casts doubt on the importance of protein quantity of PINK1 in

165 o of the three BLUF domains studied, casting doubt on the importance of the formation of a population

166 GS) to the subpolar gyre (SPG) and have cast doubt on the mechanism underlying an apparent pathway fo

167 wide variety of tasks code modality, casting doubt on the notion that these regions embody a central

168 olerance and diabetes, but cast considerable doubt on the popular thrifty genes hypothesis.

169 e human liver diseases in mice, and has cast doubt on the potential of iPSC-Heps for liver cell thera

170 ble" by current technology, which has casted doubt on the presence of amplifiable botanical DNA.

171 These data cast doubt on the previous supposition that the metabolic rat

172 nd, several arguments have emerged that cast doubt on the relevance of EF effects as a conceptual bas

173 These data cast serious doubt on the relevance of measuring urinary iodide conce

174 larger than previously recognized and casts doubt on the reliability of A(I) estimation by surfactan

175 ation of metazoan lifespan, but they do cast doubt on the robustness of the previously reported effec

176 nding sites for factor VIII (fVIII), casting doubt on the role of exposed PS as the determinant of bi

177 ed or spontaneous vocalizations, which casts doubt on the role of the frontal cortex of the Old World

178 However, recent studies have cast doubt on the role of Vps34 in autophagy, at least in cer

179 Several recent studies, however, have cast doubt on the segregation of touch discrimination and aff

180 Several recent studies, however, cast doubt on the separation of touch discrimination and affe

181 c events did not affect seep faunas, casting doubt on the suggested anoxic nature and/or global exten

182 These results cast doubt on the US EPA's recent decision to downscale its e

183 om activation of the death pathway, and cast doubt on the utility of anti-apoptotic therapies to comb

184 conditions has never been published, casting doubt on the validity of previous calibrations.

185 s the source of the catalytic power, casting doubt on the validity of the electrostatic idea, at leas

186 However, recent behavioral studies have cast doubt on the validity of this dichotomy, showing that im

187 These data cast further doubt on the value of passive immunotherapy for the trea

188 d) genistein in certain strains of mice cast doubt on the value of the use of these rodents for gaini

189 l in the Veterans Health Administration cast doubt on the value of using 30-day RSMRs as a means of i

190 These findings may cast doubt on the veracity of those studies that suggest an a

191 sal liverwort lineage Haplomitriopsida casts doubt on the widely held view that Glomeromycota formed

192 me backgrounds, but recent studies have cast doubt on their ability to substantially increase the rat

193 to rely on priors even when experience sheds doubt on their accuracy.

194 owever, recent transgenic animal models cast doubt on their direct role in AD pathology.

195 ditions of extremely weak selection, casting doubt on their general relevance.

196 ed on a medium-resolution spectrum cast some doubt on this conclusion.

197 evaluation now offered by Pinke et al. casts doubt on this hypothesis.

198 However, recent work casts doubt on this interpretation by showing that mothers wit

199 with an evolutionarily related enzyme casts doubt on this model.

200 boxyl tail of an L-type CaV1.3 channel casts doubt on this paradigm.

201 he findings to human (patho)physiology casts doubt on using a single strain to address many questions

202 However, exceptions to Errera's rule cast doubt on whether a broadly applicable rule can be formul

203 New research casts doubt on whether dental, surgical and invasive diagnosti

204 nly at z = 3.2, and recent results have cast doubt on whether dust and molecules can be found in typi

205 onment selects"[4, 5], this hypothesis casts doubt on whether geographic divergence promotes speciati

206 compared with the other methods, which casts doubt on whether its reconstructions should be favored o

207 zes required to generate these dynamics cast doubt on whether they might be observable in annual plan

208 se nearly normal in its development, casting doubt on xyloglucan's role in wall structure.

209 living males from two Bourbon branches cast doubts on its authenticity.

210 ar to detect SMAC formation in vivo has cast doubts on its functional relevance.

211 recommendations is low, and recent data cast doubts on its validity in the current era.

212 These findings raise doubts on the advantages of the currently used ISDC-ther

213 These results raised doubts on the formation of ONOO(-) per se at various flu

214 over such large distances casts considerable doubts on the general assumption that risk to ionizing r

215 ents, but lower opal accumulation rates cast doubts on the importance of the EEP as an oceanic region

216 outcome of behavioral experiments, shedding doubts on the inter-laboratory reproducibility of behavi

217 This observation casts doubts on the role of ZipA and its need for cell divisio

218 s were followed by further studies that cast doubts on their involvement.

219 with multiple sclerosis have caveats casting doubts on their validity.

220 d and legitimize their symptoms, remove self-doubt or blame, and identify factors that contribute to

221 for temporal lobe epilepsy and thus casting doubt over the conclusions drawn from semantic dementia

222 ck of activating pathway mutations have cast doubt over the significance of these observations.

223 These unexpected findings cast doubt over the utility of phosphoinositide 3-kinase inhi

224 ment of detection, there have been lingering doubts over the technique's quantitative reliability and

225 These data no doubt provide new insights into the long mystified signa

226 The existence of such neurons has been doubted recently as a result of the observation that itc

227 cialized centres and where there is room for doubt, referral to such a centre is probably wise.

228 the further addition of (unlabeled) RRM2, no doubt reflecting competition for binding to the i-motif

229 assumptions regarding causality have created doubt regarding some conclusions.

230 nfection has been uncertain, contributing to doubt regarding the utility of experimental challenge mo

231 ess, guilt over the decisions they made, and doubt regarding whether they had made the right decision

232 This, in conjunction with recently raised doubts regarding some of the Mg(2+) assignments near the

233 There have, however, long been doubts regarding the monophyletic origin of planktic for

234 ability has been thoroughly documented, some doubts remain about the precise photophysical mechanism

235 Doubts remain about the risk of temporary DAT discontinu

236 conjugation has been published to date, and doubts remain about whether such cysteine-targeting inhi

237 tional modulations of visual alpha activity, doubts remain as to the existence and functional relevan

238 -1 genes and periodontitis, but considerable doubt remains about the patient populations in which the

239 These responses no doubt represent only a small sample of the chemomechanic

240 o change substantially, in ways that will no doubt see substance use playing an increasingly large pa

241 the existence of morphogens is no longer in doubt, studies on the formation and function of their gr

242 There can be little doubt that 2006 turned out to be the annus horribilis fo

243 mediacy of Ni(0)-ate complexes, leaving some doubt that a canonical catalytic cycle consisting of an

244 There is no doubt that a simple isoquinoline alkaloid, tetrahydropap

245 lion children each year, and there is little doubt that an effective vaccine would play a central rol

246 While there is no doubt that biogenic methane production in the Arctic is

247 There is no doubt that BMDCs are not simply bystanders in the tumour

248 There is little doubt that calcium-containing crystals are involved in t

249 its vary widely, and there may be reasons to doubt that claims of efficacy reflect real-world effecti

250 ormulation, we demonstrate beyond reasonable doubt that entropy predominates the thermodynamic landsc

251 There can be little doubt that genetics has transformed our understanding of

252 There is no doubt that genomes are organized nonrandomly in the nucl

253 turized electrodes with enzymes, there is no doubt that most of the available deposition processes su

254 ugh the available body of evidence leaves no doubt that neutrophils are integral to periodontal tissu

255 ular studies, enabled us to establish beyond doubt that Nothomicrodon belongs to the Phoridae (Insect

256 There is little doubt that predictive coding is an important mechanism i

257 While there is no doubt that prevention is desirable, the evidence of the

258 Although there is no doubt that prokaryotic and organellar group II introns a

259 al performance as protease inhibitors raises doubt that propeptide stability alone is sufficient for

260 There is no doubt that the contribution of microbially mediated biop

261 k's group has demonstrated beyond reasonable doubt that the dimeric LPd(I) Br catalysts that are wide

262 Although there is little doubt that the maturation of specific inhibitory circuit

263 It is beyond doubt that the numerous, seemingly unrelated functions o

264 Although there is no doubt that the presence of multiple species during the m

265 In this study, we demonstrate beyond doubt that the slicer activity of Piwi is not required f

266 Although there is no doubt that the use of common systematic approaches for m

267 panding transmission of HCV, there is little doubt that there is a need for implementing what is in t

268 udimentary, the available evidence leaves no doubt that these small post-transcriptional regulators a

269 There is no doubt that this technology opens up a world of possibili

270 hough yet to be clearly defined, there is no doubt that transcatheter mitral valve procedures will ha

271 -level deworming; however, it remains beyond doubt that treatment reduces the severe consequences of

272 acteristic of psychosis lies in a persistent doubt that undermines the stabilization of behavioral po

273 There is little doubt that with the development of more efficient and fa

274 I had no doubt that working with kDNA would be a challenge, as I

275 Skeptics doubted that many CLs would occur, given political press

276 ospitals poor grades on patient safety, many doubted that safety was a management priority.

277 This has led to doubts that Mars can be described adequately using the '

278 The data presented here put in doubt the "regulatory cap" model of PS II, which follows

279 Specifically, we doubt the accuracy for real polyelectrolytes of the Odij

280 Many botanists doubt the existence of plant species, viewing them as ar

281 These findings call into doubt the proposed proprioceptive function of palisade e

282 appropriate control group; this brings into doubt the study's conclusions.

283 ken translational symmetry in two dimensions-doubting the existence of 2D crystals-and the first comp

284 Without a doubt, the 1985 publication by Willett et al. provided t

285 Without doubt, the literature would also benefit from bigger stu

286 gnosis of myocardial infarction (MI), beyond doubt, the most important indication of hs-cTn assays, t

287 this hydrolysis step were unknown and widely doubted to exist.

288 inconvenience), ambivalence and uncertainty (doubting transplant urgency, insufficient information, c

289 to ultraviolet radiation exposure is beyond doubt, ultraviolet-radiation-independent events are like

290 Our results cast doubt upon one of the last widely discussed pieces of ev

291 This doubt was exacerbated in a few cases as families were un

292 beginning of wisdom is found in doubting; by doubting we come to question, and by seeking we may come

293 There is no doubt whatsoever which environmental factors, probably d

294 Hence, we doubt whether Big Gods and prosocial religions are more

295 There are good reasons to doubt whether presently recognized prokaryotic species a

296 ults from recent Mars missions, calling into doubt whether the igneous histor y inferred from the met

297 the development of hypospadias, but there is doubt whether the incidence of hypospadias is increasing

298 central role of T cells has been thrown into doubt with an elegant study that assessed the effect of

299 impaired by limited sampling, and we have no doubt witnessed but a small subset of their diversity.

300 rtant and rapidly evolving area that will no doubt yield significant advances in the evaluation and t