ライフサイエンスコーパス: downregulate

1 regulated); and miR-10, miR-125, and miR-25 (downregulated).

2 nificantly different (110 upregulated and 39 downregulated).

3 , and possibly other carcinomas where Sef is downregulated.

4 oop of Henle and distal tubule lineages were downregulated.

5 dhesion and cell-to-cell communication, were downregulated.

6 fter HDAC inhibition as full-length MRE11 is downregulated.

7 e expression of the microRNA, cmo-MIR156, is downregulated.

8 d and megakaryocyte-specific transcripts are downregulated.

9 9 were significantly upregulated and 37 were downregulated.

10 receptors on basophils and mast cells to be downregulated.

11 e to iron status and strongly upregulated or downregulated.

12 ired when TET2 and nuclear factor kappaB are downregulated.

13 al precursor cell expressed, developmentally downregulated 8).

14 edes MLL leukemia cell proliferation, and it downregulates a specific group of target genes of the ML

15 are involved in secondary metabolism, while downregulating a smaller number of genes.

16 n of the follicular cell progenitors, but is downregulated after birth.

17 ctron transport pathways to be significantly downregulated after RK-33 or DDX3 knockdown.

18 d potencies as antiproliferative and ERalpha-downregulating agents.

19 monstrate that GLI3R represses AML growth by downregulating AKT expression.

20 than males, which correlates well with their downregulated amino and fatty acid metabolism.

21 log2 = 1.8, 3.5-fold change), 670 genes were downregulated and 296 genes were upregulated.

22 Knockdown of USP9X significantly downregulated and destabilized LATS and resulted in enha

23 reated cardiomyocytes, CBS and miR-133a were downregulated and hypertrophy was induced.

24 dings, lipogenic and lipid uptake genes were downregulated and lipid oxidation enhanced in obese BLKO

25 high in all subpopulations at diagnosis but downregulated and unevenly distributed across subpopulat

26 nd downregulated, respectively, in mTBI, but downregulated and upregulated, respectively, in sTBI.

27 processes (motility and bioluminescence) are downregulated, and microarray-based transcriptomics demo

28 ertension (PAH) in which apelin signaling is downregulated, and to demonstrate attenuation of PAH sev

29 ber of immune and cancer cells, where it can downregulate antitumor immune responses.

30 l differentiation genes pax6b and mnx1 while downregulating arxa, a master regulator of alpha-cell de

31 ertebrate gonadotropin-releasing hormone, is downregulated as workers become gamergates.

32 The most promising oligonucleotide, ASO7, downregulated ATXN2 mRNA and protein, which resulted in

33 s with the familial adenomatous polyposis by downregulating beta-catenin signaling.

34 We show here that it is a developmentally downregulated but dynamic component of KARs in these neu

35 of the kinetochore complex subunit Ndc80 is downregulated by a 5' extended long undecoded NDC80 tran

36 T1), which catalyzes H4K5ac and H4K12ac, was downregulated by ascorbate mainly via the TET-mediated D

37 e components of the beta-catenin pathway, is downregulated by clofibrate.

38 rain, and has been previously reported to be downregulated by cocaine.

39 miR-23a-3p, miR-23b-3p, and miR-149-5p, were downregulated by cytokines and selected for further stud

40 HLA-E protein expression on cell surface is downregulated by high-risk HPV16 and HPV18 E7 expression

41 f airway epithelial barrier function that is downregulated by IL-13 and that claudin-18 deficiency re

42 ologs of Drosophila Dys, Trio, and Shot were downregulated by introducing a C-terminal truncated muta

43 lling the expression of several of the genes downregulated by JAK2 knockdown, we questioned whether T

44 In our model, the hedgehog pathway was downregulated by Mtb-stimulation, but Shh levels in astr

45 ells in which the RhoA signaling pathway was downregulated by multiple experimental approaches.

46 ression of miR-193b in liposarcoma cells was downregulated by promoter methylation, resulting at leas

47 , HIF1a, MTIF and CDKN1B) are reported to be downregulated by the loss of PRMT5, while their mRNA lev

48 oRNAs (miRs), miR-126 and miR-126*, that are downregulated by TNFalpha and IFNgamma in a human brain

49 ouse insulin-secreting PNET cell line, MIN6, downregulates c-Met expression.

50 NA FILNC1, which inhibits survival of RCC by downregulating c-Myc and c-Myc-dependent metabolic rewir

51 ion repressed cell survival by targeting and downregulating c-Myc.

52 of mTORC2 inhibitor in the treatment of MFN2 downregulated cancer patients.

53 found that homocysteine upregulates CSE but downregulates CBS whereas Na2S/GYY4137 downregulates CSE

54 he immune response resolved, some Treg cells downregulated CD25, upregulated Bcl-6 and differentiated

55 cells expressed IL-4, upregulated CD69, and downregulated CD62L.

56 The Vpu protein of HIV-1 functions to downregulate cell surface localization of host proteins

57 phosphorylation of the alpha-subunit of eIF2 downregulates cellular protein synthesis.

58 upregulating the Nrf2 signaling pathway, but downregulating cellular apoptosis in lung cancer cells.

59 (HBEC) confirm that cigarette smoke not only downregulates CFTR activity but also inhibits BK channel

60 administration of angiotensin II for 2 weeks downregulated collectrin expression in a type 1 angioten

61 roteins of ARV to negatively regulate Akt by downregulating complexes of mTORC2 and CDK2/cyclin A2 an

62 E but downregulates CBS whereas Na2S/GYY4137 downregulates CSE but upregulates CBS in a dose-dependen

63 ion signal in CELF1 abolished the ability to downregulate Cx43 mRNA, so nuclear localization was requ

64 nockdown of endogenous RRP6, CELF1 failed to downregulate Cx43 mRNA, which suggests that RRP6 was req

65 t a mechanism for increased CELF1 expression downregulating Cx43 mRNA level and a pathogenic role for

66 6), (ii) may promote (CXCL10, CCL2, CCL5) or downregulate (CXCL9) initial granuloma assembly, (iii) m

67 ation by inducing G1/S transition arrest and downregulating cyclin D1 expression, while the prolifera

68 Following CCI injury, hippocampal neurons downregulated d-serine levels, while astrocytes enhanced

69 ortation was also significantly enriched for downregulated DEGs on day 35.

70 ge, with chondromodulin, collagen types II/X downregulated, deiodinase II and netrin-1 upregulated.

71 Amongst Y-linked genes that were downregulated due to LOY, KDM5D and KDM6C epigenetic mod

72 y expressed in the megakaryocyte lineage but downregulated during erythropoiesis.

73 rrying t(11q23), t(15;17), or t(8;21) and is downregulated during myeloid differentiation.

74 ing mammary development, Ptprb expression is downregulated during puberty, a period of extensive duct

75 S1PR1 was progressively downregulated during T cell differentiation whereas S1PR

76 s of mouse and human epidermis and cSCC, and downregulated during terminal differentiation.

77 Consistent with this finding, NLRP3 was downregulated during the differentiation of monocytes to

78 ls, with the ability to independently up- or downregulate each over time.

79 ogic induction of ER stress with tunicamycin downregulated endothelial Cav1 and impaired endothelium-

80 stress within the tumor microenvironment by downregulating energy-consuming processes including tran

81 well as mitochondrial remodeling and led to downregulated expression and activity of respiratory cha

82 pe kidneys, and immunoblot analysis revealed downregulated expression of FXR in HNF-1beta mutant kidn

83 or FSGS glomeruli, IgAN glomeruli exhibited downregulated expression of hsa-miR-3182.

84 srupted organization of endothelial F-actin, downregulated expression of occludin and remodelling of

85 inhibitor of metalloproteinases 1 (TIMP-1), downregulated expression of proinflammatory cytokines/ch

86 Genome-wide expression profiling revealed downregulated expression of the gene encoding the glycop

87 presence of anti-IFN-gamma antibodies, SAHM1 downregulated expression of the key TH2 transcription fa

88 MIA downregulates expression of ASD-associated genes, with t

89 MIA also downregulates expression of many genes also known to be

90 Moreover, rIL-15 delivery to the lung downregulates expression of proinflammatory cytokines an

91 ting MUC1-C in diverse human carcinoma cells downregulates EZH2 and other PRC2 components.

92 concert with these results, targeting MUC1-C downregulates EZH2 function as evidenced by (i) global a

93 pulations, while the Clade IV representative downregulated Fe-limitation proteins.

94 +) pre-selection thymocytes is progressively downregulated following both MHC and CD1d-restricted thy

95 all Kv4 complex components in DRG neurons is downregulated following spinal nerve ligation (SNL).

96 ly(I:C), and 12, 142, 249, and 16 genes were downregulated for LTA, LPS, Poly(dT), and Poly(I:C), res

97 Furthermore, MK-4166 downregulated FOXP3 mRNA in human tumor infiltrating Tre

98 show that, when SCs become myelinating, they downregulate functional AMPARs.

99 Here, we show that gamma2 AMPK activation downregulates fundamental sinoatrial cell pacemaker mech

100 exceptionally low temperatures are needed to downregulate FvTFL1 and to make these plants competent t

101 cells are more efficient in their ability to downregulate FXIIIA than in contributing to its amounts

102 ral precursor cell expressed developmentally downregulated gene 4-like; chromosome 18), Ano6 (anocatm

103 vealed significant overlaps between p300/CBP-downregulated genes and genes downregulated in Hnf1alpha

104 Downregulated genes corresponded to an intracytoplasmic

105 Interestingly, downregulated genes exhibit reduced polymerase levels in

106 Thirteen transcriptionally downregulated genes linked to promoter or enhancer hyper

107 ted by MeCP2 mutations, with upregulated and downregulated genes reflecting distinct functional categ

108 S: Seven hundred and forty-three up- and 326 downregulated genes were differentially expressed in HDM

109 The downregulated genes were tightly linked to regulation of

110 uroinflammatory response through its role in downregulating glial activation, however, the intact apo

111 Inhibition of CB1R also downregulated GLUT2 expression, affected the dynamic tra

112 restored catecholamine-induced lipolysis by downregulating growth differentiation factor-3 (GDF3) an

113 that 214 mRNAs were upregulated and 149 were downregulated >3-fold by IL-4 in a STAT6-dependent manne

114 complex, restored mRNA levels for a class of downregulated, H3K36me3-rich genes.

115 Strikingly, Fgf21 was the most downregulated hepatic gene.

116 ate the pathway but also sequesters Kibra to downregulate Hippo signaling.

117 ppaB-activating kinase IKKbeta cooperatively downregulated histone H4 expression, which increased cis

118 s harboring nonconsensus variants at codon 9 downregulated HLA-B (though not HLA-A) significantly bet

119 ata showed that exogenous DHEA significantly downregulated IGF-1 and its receptor in both HCFs and HK

120 nd healing phase and reduced inflammation by downregulating IL-1beta during the late wound healing ph

121 transcript, protein and activity levels were downregulated in a largely ERFVII-dependent manner.

122 ous Dnmt1 gene transcription could be up- or downregulated in a tunable, inducible, and reversible ma

123 We show that RARRES2 expression is downregulated in ACC as compared with normal and benign

124 hippocampal expression that was upregulated/downregulated in aged controls (ACs) compared with YCs (

125 We found FOXP1 to be significantly downregulated in both EZH2- and MEF2B-mutated cases.

126 xtrinsic apoptosis and its activity is often downregulated in cancer.

127 ly expressed, 2 were upregulated and 14 were downregulated in children with active CMA compared to he

128 CN (CYR61/CTGF/NOV) family, is significantly downregulated in clinical samples of human spindle cell

129 egulator class II transactivator (CIITA) are downregulated in CML compared with non-CML stem/progenit

130 a crucial player in pyruvate metabolism, is downregulated in colon adenocarcinomas.

131 , a tumor invasion suppressor, is frequently downregulated in colorectal cancer and other cancers.

132 groups, of which 62 were upregulated and 98 downregulated in control vs. Trpc3-deficient M1 macropha

133 ls of lipoprotein ApoA1 expression, which is downregulated in Crohn's disease patients and causally l

134 iling demonstrated that miR-30a was markedly downregulated in diabetic cataract tissues.

135 Accordingly, miR-200s are downregulated in Dicer-KO CDs, its direct target genes Z

136 Moreover, the FGF10 pathway is downregulated in Dlx5(-/-) mice, and activation of FGF10

137 ple, ERO1LB, DOCK10, IGSF11, and PRR14L were downregulated in donors with hyperglycemia and correlate

138 of local RA concentrations, is significantly downregulated in embryos of diabetic mice.

139 we demonstrated that expression of FBP1 was downregulated in HCC patient specimens and decreased exp

140 P2Y14 R is downregulated in hCPCs derived from HF patients with low

141 o expressed selectively, neuroprotective and downregulated in HD mice and patients.

142 PEPCK and G6Pase transcript levels are downregulated in hepatocytes from GCN5L1 liver specific

143 obustly regulated by BDNF/TrkB signaling, is downregulated in hippocampus (male/female) and upregulat

144 tween p300/CBP-downregulated genes and genes downregulated in Hnf1alpha-null islets and Nkx2.2-null i

145 portant for the acetylation of H3K27 at loci downregulated in Hnf1alpha-null islets.

146 that expression of the MHC class I genes is downregulated in HPV-positive keratinocytes in an E7-dep

147 main-containing 1 (PDZK1) was revealed to be downregulated in human clear cell renal cell carcinoma (

148 Importantly, FOXA1 is downregulated in human NEPC tumors compared to primary a

149 Furthermore, SIN3B was downregulated in human prostate adenocarcinoma correlati

150 SIRT2 protein expression levels were downregulated in hypertrophic hearts from mice.

151 In humans, ESRP1 is downregulated in inflamed biopsies from inflammatory bow

152 a-ketoacyl CoA synthase gene (PotriKCS1) was downregulated in leaves from non-alkene-producing access

153 miR-218 expression levels were significantly downregulated in lung cancer tissues compared with adjac

154 PML is frequently downregulated in many cancer types, including lung cance

155 er (MDD) have noted that the cAMP cascade is downregulated in MDD and upregulated by antidepressant t

156 in PTSD, including one wound-healing module downregulated in men exposed to combat traumas, one IL-1

157 r responder 2 (RARRES2) is transcriptionally downregulated in multiple cancer types.

158 We find that LINC-PINT is downregulated in multiple types of cancer and acts as a

159 t baseline in fresolimumab nonimprovers were downregulated in mycophenolate mofetil improvers, sugges

160 reporter' because its expression is strongly downregulated in normal adult lymphatic endothelial cell

161 (cGMP-dependent protein kinase) activity was downregulated in Npr2(+/-) valves, and CNP triggered syn

162 Here we demonstrated that miR-26a is downregulated in osteosarcoma CSCs when derived by eithe

163 While CHIP is downregulated in ovarian carcinoma, induced expression o

164 3, are preferentially expressed in PTECs and downregulated in patients with DN.

165 the histone demethylase JARID1B, MANTIS was downregulated in patients with idiopathic pulmonary arte

166 PPARD was downregulated in prostate cancer specimens.

167 mponent of this region-miR-383-is frequently downregulated in prostate cancer, has a critical role in

168 N-termini of several proteases were downregulated in prt6, including RD21A.

169 is specifically expressed in kidney, and is downregulated in renal cell carcinoma; also, its low exp

170 MAPK pathway, as well as redox enzymes were downregulated in response to disruption of glutamine met

171 ing) in response to doxorubicin was strongly downregulated in rodent cardiomyocytes and human induced

172 was significantly elevated in moderate while downregulated in severe asthma.

173 olved in cellular redox homeostasis which is downregulated in skeletal muscle differentiation.

174 a and guanylate-binding proteins (GBPs), are downregulated in STING knockout (KO) macrophages infecte

175 a key enzyme in cAMP and cGMP catabolism, is downregulated in striatal projections to entopeduncular

176 Notably, Pla2g1b was downregulated in susceptible mice and inhibited by IL-4R

177 uction and subsequent T cell recruitment, is downregulated in TAMs through Mer tyrosine kinase-depend

178 hologue (14-3-3 protein zeta/YWHAZ) that was downregulated in temporary ponds in both species.

179 e both induced by long-term potentiation and downregulated in the aged brain.

180 of many genes also known to be persistently downregulated in the ASD cortex later in life and which

181 Zeb2 levels are downregulated in the embryonic rodent midbrain during th

182 46 genes were upregulated and 200 genes were downregulated in the fibrotic cell lines compared to the

183 mucus showed that 60% of the genes that were downregulated in the luxO mutant were involved in amino

184 Sonic hedgehog (Shh) signal transduction was downregulated in the mutant forebrain, consistent with a

185 miR-495 expression was also downregulated in the NAcsh of rats following cocaine sel

186 ries in the mouse, as E-cadherin needs to be downregulated in the primitive streak and in the epiblas

187 nsmembrane ligand for the NOTCH receptor, is downregulated in the PTEN-null fibroblasts leading to a

188 CCN5 was overexpressed in the NSP but downregulated in the SP.

189 known to be involved in spermatogenesis were downregulated in the testes of knock-out mice, as well a

190 mTOR (p=0.03) and PI3K-alpha (P = 0.04) were downregulated in treatment responsive residual tumors, w

191 transcription factor, was >twofold altered (downregulated) in MET mice; strikingly, similar Npas4 do

192 oxia-induced genes, of which two-thirds were downregulated including CA9 and VEGF-A.

193 f the SUMO E2 conjugase enzyme, Ubc9, at K65 downregulates its binding to the NDSM and renders a sele

194 ctly targets the 3' UTR of GLP1R and thereby downregulates its expression in the beta-cell-derived ra

195 dictive of expression of viral proteins, and downregulating Ki67 leads to concurrent decreases in exp

196 C1q downregulated levels and activity of active caspase-3 an

197 in EAU and in mouse CD4(+) T cells in vitro, downregulating levels of Th17 cells.

198 selectively overexpress (Lin28aKI(VMH) ) or downregulate (Lin28aKD(VMH) ) Lin28a expression in mice.

199 Co-cultured diatoms also downregulated lipid biosynthesis genes and upregulated c

200 d oxidative/thermogenic gene expression, and downregulated lipolysis and lipogenesis genes in epididy

201 rophages to oxidized low-density lipoprotein downregulated LKB1 in vitro.

202 f the mutant allele in PF-382 cells markedly downregulated LMO2 expression, establishing clear causal

203 .5) and Gja5 (connexin 40), are persistently downregulated long after a transient Notch pulse.

204 rol regulatory-element binding protein 2 and downregulating low-density lipoprotein receptor expressi

205 Microarray analysis suggested downregulated macrophage migration inhibitory factor (MI

206 HIV-1 group M subtypes for their ability to downregulate major histocompatibility complex class A (M

207 proliferation, invasion, and tumor growth by downregulating MAPK pathway activity.

208 uggest that Nanos promotes germ cell fate by downregulating maternal RNAs and proteins that would oth

209 -positive interneurons primarily function to downregulate medium spiny projection neuron (MSN) activi

210 gulated (testis-specific gene expression) or downregulated (metabolism and mitochondria-related funct

211 s demonstrate that Nef's inferior ability to downregulate MHC-B compared to that of MHC-A is conserve

212 ation abilities, all lentiviral Nef lineages downregulated MHC-A, on average, 11 to 32% more efficien

213 we demonstrate that age-related IFN-I milieu downregulates microglial myocyte-specific enhancer facto

214 We show Sox2 downregulates miR-452, which acts as a novel metastasis

215 miR-193a-5p resulted the most downregulated miRNA in children with active CMA compared

216 miR-210 was the most significantly downregulated miRNA in local plasma material.

217 We identify miR-327 as one of the most downregulated miRNAs targeting growth factors in the str

218 Downregulated miRNAs were associated with increased expr

219 overexpression of constitutively active AMPK downregulated mitochondrial superoxide, lowered levels o

220 ersed these cocaine-induced effects but also downregulated multiple ARG mRNAs in specific SUD-related

221 nchymal and stemness-like properties through downregulating multiple inhibitors of Wnt/beta-catenin a

222 or of BET bromodomains, (+)-JQ1, selectively downregulated MYC transcription, which is similar to wha

223 y reduces NF-kappaB nuclear localization and downregulates NF-kappaB targets.

224 ich significantly promoted ROS production by downregulating nicotinamide adenine dinucleotide(+) (NAD

225 NK cells from STAT3 wild-type mice downregulate NKG2D in response to VPA, but not NK cells

226 reating and concomitant opioid release could downregulate opioid receptors and promote the developmen

227 ered that C646, a reversible p300 inhibitor, downregulates p53 transcription and selectively protects

228 e by associating with Argonaute proteins and downregulating partially complementary messenger RNAs (m

229 On the other hand, downregulating PCK2 hindered fumarate carbon flows in TC

230 our findings show how GSK-3 inhibitors that downregulate PD-1 expression can enhance CD8(+) T-cell f

231 hese findings show how GSK-3 inhibitors that downregulate PD-1 expression can enhance CD8(+) T-cell f

232 y prompts exploration of other strategies to downregulate PD-1 for cancer therapy.

233 e, we found that blockade of STAT3 signaling downregulated PD-1/PD-L1 in a Tgfbr1/Pten 2cKO HNSCC mou

234 Downregulating PGRP-SB2 selectively in the fat body prot

235 eleterious effects of overnutrition, whereas downregulating PGRP-SC2 produced InR-like phenotypes.

236 All strains downregulated phycobilisome proteins with increasing irr

237 acological concentration of ATRA effectively downregulates PKCzeta through activation of miR-200c, le

238 se (1) periadolescent HFD (pHFD) selectively downregulates prefrontal RELN(+) cells and (2) augmentin

239 d PRMT in epidermal progenitors and the most downregulated PRMT during differentiation.

240 Activation of AMPK was shown to downregulate PXR activity and, consistent with that, pot

241 ucing fusion or fission were upregulated and downregulated, respectively, in mTBI, but downregulated

242 hile decreasing mitochondrial respiration by downregulating respiratory chain complexes I and III.

243 In addition to downregulating ribosomal proteins, p17 reduces mTORC2 as

244 lockade of AKT, HSF1 or HuR is sufficient to downregulate Rictor and inhibit GBM growth and invasive

245 Moreover, AZD4547 downregulated RTK, mTOR, and Wnt/beta-catenin signaling

246 effect of SDF-1 antagonism, most probably by downregulating SDF-1 and the second receptor of the chem

247 s with severe therapy-refractory asthma that downregulates selectively structural abnormalities invol

248 virally mediated RNA interference to locally downregulate SERT expression and compared the results wi

249 bservations (i.e., LPS upregulated Wnt5a and downregulated sFRP5).

250 at Sonic Hedgehog (Shh)-Smoothened signaling downregulates Shisa2, which inhibits the glycosylation a

251 A miR-204 mimic leads to ER stress and downregulates Sirt1 in endothelial cells.

252 ut left a large surviving subpopulation with downregulated SMAD2/3.

253 bility to metastasize in vivo constitutively downregulated SNPH and exhibited higher oxidative stress

254 These cells produce IL-10 and downregulate some pro-inflammatory genes.

255 indings assigning the ouchless phenotypes to downregulated sorbs3 transcript levels, this work re-att

256 Moreover, the Na2S-treatment downregulates specificity protein-1 (SP1), an inducer fo

257 Our study shows that downregulating specificity protein 1 (Sp1), a transcript

258 nase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1.

259 e report optogenetic tools to upregulate and downregulate such forces with high spatiotemporal accura

260 2) twice as many mRNAs were upregulated than downregulated, suggesting that Setd1b also promotes the

261 presumably on myeloid APCs, were required to downregulate T cell help for the extrafollicular respons

262 stress-dependent increase in miR101c, which downregulated Tet1 in hematopoietic stem cells (HSC), re

263 Specifically, ketamine tended to downregulate the adenosine triphosphate (ATP)/adenosine

264 E mAbs was correlated with their capacity to downregulate the surface IgE and FcepsilonRI level on hu

265 us-induced shutoff of host protein synthesis downregulated the abundance of RNA5SP141-interacting pro

266 mpared to Nos and DTX alone respectively and downregulated the expression of anti-apoptotic factors a

267 ell surface expression of langerin on LC but downregulated the expression of DC-SIGN on iDDC, as we p

268 Furthermore, PGE2 downregulated the expression of IL-2 receptor alpha (CD2

269 onstrate that stimulation with trophic forms downregulated the expression of multiple genes normally

270 Notably, JQ1 downregulated the expression of several genes controlled

271 systemic administration of anti-DC-STAMP-mAb downregulated the ligature-induced alveolar bone loss.

272 Nicotine at 10 micromol/L significantly downregulated the release of TNF-alpha, but showed a les

273 Acute injection of recombinant cKL downregulated the renal sodium-phosphate cotransporter N

274 IL-10-producing drug-specific T cell clones downregulated the response of autologous effector T cell

275 We found that Drosophila miR-263a downregulates the expression of epithelial sodium channe

276 In addition, exercise/HIF-1alpha downregulates the expression of TXNIP, a well-known nega

277 we show that increasing UBE3A in the nucleus downregulates the glutamatergic synapse organizer Cbln1,

278 iously reported that the S. aureus cell wall downregulates the human T cell response to superantigens

279 Here, we demonstrate that a viral miRNA downregulates the IL-1 receptor 1 during EBV infection,

280 inhibition of Rho-associated kinase (ROCK)2 downregulates the proinflammatory T cell response while

281 duals having higher HRV being better able to downregulate their cravings in the face of taste temptat

282 being consistent to previous findings, they downregulated their respiration to sustain their growth

283 Rather, by downregulating their voltage-activated calcium channels,

284 function which can lead to tumorigenesis by downregulating these genes.

285 iltration (P <0.01) as well as significantly downregulated TLR2 (P <0.05), RAGE (P <0.01), and TNF-al

286 ral precursor cell expressed developmentally downregulated) to specific targets, is aberrant in many

287 Age-downregulated transcripts are significantly enriched in

288 Downregulated transcripts were enriched for mitotic proc

289 und that focal adhesion kinase expression is downregulated under a high glucose condition both in vit

290 All but one miRNA were downregulated upon decidualization, including miR-542-3p

291 and sphingomyelins were found significantly downregulated upon inflammatory stimulation.

292 ssion of miR-200 family members was markedly downregulated upon wounding in both young and aged mice,

293 Importantly, when endogenous IKKepsilon was downregulated using a small interfering RNA approach, SP

294 ted 11 genes that were highly upregulated or downregulated using real-time quantitative PCR and found

295 ylation of 239 proteins was identified to be downregulated, while phosphorylation of 47 proteins was

296 sent study, the expression of E-cadherin was downregulated, while the expression of alpha-SMA and vim

297 ich can promote tumor growth, was remarkably downregulated, while the tumor suppressor proteins p53 a

298 Cell adhesion genes, JAM-A and FSCN1, were downregulated with overexpression of miR-143 and miR-145

299 We found that both CYP4B1 and RAB25 are downregulated with promoter hypermethylation and CA9 is

300 siRNA screen to identify kinases that, when downregulated, yield sensitivity to the CDK4/6 inhibitor