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1 ne Brugia malayi model of minocycline versus doxycycline.
2 ice, and the double-transgenic mice were fed doxycycline.
3 ound expression and increased sensitivity to doxycycline.
4 n, and 283 were randomly assigned to receive doxycycline.
5 ced number of dead worms were observed after doxycycline.
6 4, 5, or 6 weeks of daily 100 or 200 mg oral doxycycline.
7 filariae more rapidly than those achieved by doxycycline.
8 trimethoprim-sulfamethoxaxole (TMP-SMX) plus doxycycline.
9 ter treatment with topical steroids and oral doxycycline.
10 expression was then ablated by withdrawal of doxycycline.
11 tages of IV minocycline over tigecycline and doxycycline.
12 or absence of penicillin, ciprofloxacin, or doxycycline.
13 ncreases were attenuated by azithromycin and doxycycline.
14 TMP-SMX plus placebo and 315 to TMP-SMX plus doxycycline.
15 ints did not fit the susceptibility data for doxycycline.
16 xpressed, but can be modulated in vivo using doxycycline.
17 -B cell line in which PU.1 can be induced by doxycycline.
18 xpression of oncogenic K-RAS is regulated by doxycycline.
19 ) or onchocerciasis (Onchocerca volvulus) is doxycycline.
20 tients treated with the anti-Wolbachia drug, doxycycline.
25 etronidazole and amoxicillin in combination, doxycycline (2 mug/mL), and azithromycin (10 mug/mL) ove
27 Second, a double-blind randomization between doxycycline (200 mg/day, once daily) and placebo was per
28 stant, among which 51.4% were susceptible to doxycycline, 29.7% to clindamycin, and 21.6% to trimetho
29 corticosteroids (1-3 weeks), short course of doxycycline (3 weeks), or a leukotriene antagonist may b
31 At EOT, fatigue severity was similar between doxycycline (40.8 [95% confidence interval {CI}, 37.3-44
33 The PED + LDD group was treated orally with doxycycline (6 mg/kg) for 21 days after the ligature was
34 ortetracycline (5), oxytetracycline (6), and doxycycline (7) were biotransformed by a marine-derived
36 clinical isolates were resistant in vitro to doxycycline, 98% were only intermediate in susceptibilit
37 ine depletes Wolbachia more effectively than doxycycline (99.51% vs. 90.35%) after 28 day 25 mg/Kg bi
46 cin, azithromycin, rifampin, gentamicin, and doxycycline against 101 isolates of Rhodococcus equi wer
47 for testing of minocycline, tigecycline, and doxycycline against 107 carbapenem-resistant A. baumanni
52 omycetemcomitans, were resistant in vitro to doxycycline, amoxicillin, metronidazole, or clindamycin,
53 mono- or dual therapy (with azithromycin or doxycycline), anal, vaginal, or urine samples were self-
54 2013, 132 patients were randomly assigned to doxycycline and 121 to prednisolone from 54 UK and seven
55 ier estimates were 16.1% for those receiving doxycycline and 16.5% for those receiving placebo; diffe
57 eeks were 18% (22 of 121) for those starting doxycycline and 36% (41 of 113) for prednisolone (mITT),
58 domized trials demonstrated poor efficacy of doxycycline and better, but declining, efficacy of singl
59 ates confirming synergy with Clarithromycin, Doxycycline and Clindamycin, combinations of which were
60 tor-initiated multicenter trials highlighted doxycycline and dapsone as valuable medications in the t
62 zelaic acid, and ivermectin, as well as oral doxycycline and isotretinoin, are associated with improv
65 ormation at the monomer stage, we found that doxycycline and rifamycin SV exert their effect by bindi
67 ld type beta2-microglobulin fibrillogenesis, doxycycline and single domain antibodies (nanobodies).
69 d 52.3% for minocycline, 21.5% and 18.7% for doxycycline, and 71% and 29.9% for tigecycline, respecti
70 broth were 77.6% for minocycline and 29% for doxycycline, and 92.5% of isolates had tigecycline MICs
71 pinpoint the binding sites of rifamycin SV, doxycycline, and another molecule, suramin, which binds
72 nd carbadox, heterogeneous susceptibility to doxycycline, and low susceptibility to lincomycin and ty
74 ms when compared directly with tetracycline, doxycycline, and other broad-spectrum antimicrobial agen
75 well tolerated and commonly used antibiotic doxycycline as a potent inhibitor of M2-type polarizatio
78 moxicillin at 8 mg/L, clindamycin at 4 mg/L, doxycycline at 4 mg/L, and metronidazole at 16 mg/L, wit
79 ve IV boluses of normal saline (control) and doxycycline at 5 minutes of reoxygenation (n = 7/group).
80 ibitory response in the presence of the drug doxycycline at the single-cell level to reveal their het
82 or the microglia antagonists minocycline and doxycycline augmented sympathetic responses to KA-induce
83 cterial counts were significantly reduced by doxycycline, azithromycin, and amoxicillin alone or in c
86 sed a 161% increase, whereas minocycline and doxycycline caused a 225% and 215% increase, respectivel
88 dorferi--to receive a 12-week oral course of doxycycline, clarithromycin plus hydroxychloroquine, or
89 e a small increased efficacy of up to 3% for doxycycline compared with azithromycin for the treatment
92 we show that expression of the tetracycline/doxycycline-controlled Tet-transactivator, while tolerat
94 4 were randomized to azithromycin and 302 to doxycycline; CT, MG, TV, and UU-2 were detected in 24%,
96 Recognition of risk factors associated with doxycycline delay and fatal outcome, such as early gastr
98 line of mice that expresses an inducible and doxycycline-dependent GFP-GluN2A transgene specifically
103 l fibroblasts, expressing miR-449b through a doxycycline (dox) induced expression system were used as
104 Tat expression is induced by activation of a doxycycline (Dox) promotor, we tested the effects of Tat
105 bjective of the present study is to quantify doxycycline (DOX) release from beta-tricalcium phosphate
106 or protein transgenic mice were treated with doxycycline (dox) to suppress further amyloid precursor
109 onding characteristics to dentin of a unique doxycycline (DOX)-encapsulated halloysite nanotube (HNT)
120 tance, was diminished in allergen-challenged doxycycline-exposed compared with non-doxycycline-expose
124 receive TMP-SMX plus placebo or TMP-SMX plus doxycycline for 20 weeks (1:1; block size of ten, strati
126 and prescription of a 14-day course of oral doxycycline for early neurologic Lyme disease in ambulat
129 that TMP-SMX is not inferior to TMP-SMX plus doxycycline for the oral phase of melioidosis treatment,
130 nd side-effects of TMP-SMX with TMP-SMX plus doxycycline for the oral phase of melioidosis treatment.
131 ontrolled trials comparing azithromycin with doxycycline for the treatment of genital chlamydia with
132 hlamydia and about 7% increased efficacy for doxycycline for the treatment of symptomatic urethral in
133 mized trial comparing oral azithromycin with doxycycline for the treatment of urogenital chlamydia in
134 ocerca volvulus Wolbachia endosymbionts with doxycycline for these individuals with suboptimal respon
135 ampin represents an effective alternative to doxycycline for treatment of African tick bite fever in
136 e shown efficacy for a 10-day course of oral doxycycline for treatment of erythema migrans and for a
137 re evaluated in groups of mice that received doxycycline for varying periods from 0 to 40 weeks of ag
142 hether a strategy of starting treatment with doxycycline gives acceptable short-term blister control
145 A higher mean FDP foveal sensitivity in the doxycycline group compared with the placebo group was de
146 oup and 21 patients (7%) in the TMP-SMX plus doxycycline group developed culture-confirmed recurrent
147 fference of 0.2 [95% CI, -2.4 to 2.8] in the doxycycline group vs. the placebo group and a difference
148 nfidence interval [CI], 33.5 to 36.5) in the doxycycline group, 35.6 (95% CI, 34.2 to 37.1) in the cl
149 ention-to-treat analysis (86 patients in the doxycycline group, 96 in the clarithromycin-hydroxychlor
151 tis and placebo treatment; and 3) ligature + doxycycline group: ligature-induced periodontitis and SD
152 ystemic arterial pressure ratio was lower in doxycycline groups, with reduced levels of markers of my
156 significant association between the cost of doxycycline hyclate and market concentration as assessed
159 Between 2011 and 2013, the mean cost of doxycycline hyclate prescriptions increased from $7.16 t
163 tor system was observed with the addition of doxycycline in drinking water, confirming that the cysta
164 expected to be 1.7 fold more effective than doxycycline in man despite lower exposure in our infecti
165 be too small to detect a treatment effect of doxycycline in patients with mild to moderate NPDR.
167 ession (17.7- to 73-fold) in the presence of doxycycline in several endothelial cell lines, but witho
168 gate the effects of the local application of doxycycline in the form of natrosol-based gel on bone re
170 trary to expected results, combined BMP2 and doxycycline induced a statistically significant (P <0.00
171 e significantly reduced or absent in TPA- or doxycycline-induced cells expressing lytic KSHV proteins
172 oss of folates was not measurable from these doxycycline-induced cells or from parental CHO cells ove
174 we use a novel transgenic mouse model, where doxycycline-induced overexpression of vascular endotheli
175 letion in MCF10A cells engineered to express doxycycline-induced shHOXA5 slowed transition of cells f
177 ablished HEK293 cell lines stably expressing doxycycline-inducible (Tet-on) reference APOL1 G0 or the
182 These observations were further validated in doxycycline-inducible CC10-IL-15 bitransgenic mice.
183 ed Gfi-1b allele in combination with a novel doxycycline-inducible Cre transgene that efficiently med
185 fts of neuroblastoma cells stably expressing doxycycline-inducible DOT1L shRNA, ablating DOT1L expres
186 ntiviral-based DUX4 expression in myoblasts, doxycycline-inducible DUX4 in myoblasts, and differentia
188 this hypothesis, we generated cell lines for doxycycline-inducible expression of short hairpin RNAs (
189 ch signaling within adult myocardium using a doxycycline-inducible genetic system (inducible Notch in
190 could be readily transduced to NRVMs by the doxycycline-inducible lentiviral system; however, high-l
191 The present work aimed to examine how the doxycycline-inducible lentiviral-mediated ChR2 expressio
192 ycle induction in TREX-BCBL-1 cells with the doxycycline-inducible lytic cycle switch replication and
194 iption of lentiviral vector sequences from a doxycycline-inducible promoter eliminated superinduction
195 ic isoforms of human FPGS under control of a doxycycline-inducible promoter in the AUXB1 cell line.
197 colonized tumors of patients, we discuss the doxycycline-inducible promoter system adjustment and fur
198 address this, we developed a cell line with doxycycline-inducible RTA expression and applied stable
199 ed several single, endothelial-specific, and doxycycline-inducible self-inactivating (SIN) lentiviral
200 y means of CRISPR/Cas9-mediated knockout and doxycycline-inducible short hairpin RNA-mediated knockdo
202 ifically, we introduced a podocyte-specific, doxycycline-inducible transactivator into a murine embry
203 n of a claudin-1 transgenic mouse model with doxycycline-inducible transgene expression specifically
211 dence indicates that a 10-day course of oral doxycycline is effective for HGA and that a 7- to 10-day
215 hema migrans for no longer than 10 days when doxycycline is used and prescription of a 14-day course
216 Subantibiotic doses of doxycycline (low-dose doxycycline [LDD]) have been widely used in periodontal
217 achyspira murdochii to tiamulin, valnemulin, doxycycline, lincomycin, and tylosin by broth microdilut
218 ICs to amoxicillin, cefotaxime, ceftriaxone, doxycycline, linezolid, meropenem, penicillin, rifampin,
221 ocular adnexal MALT lymphomas where upfront doxycycline may be a reasonable and effective initial tr
222 Our findings suggest that azithromycin and doxycycline may be effective adjuvants to standard antia
224 8 microg/mL) displayed greater activity than doxycycline (MIC(50/90): 2/>8 microg/mL) and tetracyclin
226 MICs versus corresponding zone diameters and doxycycline MICs versus zones were prepared, and analysi
227 ch investigations that evaluated the role of doxycycline, minocycline, and azithromycin in OSD among
229 Patients were randomized to receive 50 mg of doxycycline monohydrate or placebo daily for 24 months.
230 t Diabetic Retinopathy Study level 20-43) to doxycycline monohydrate, 50 mg/d, or daily placebo for 2
232 und a pooled efficacy difference in favor of doxycycline of 1.5% (95% confidence interval [CI], -.1%
233 ters are pertinent to the prospects of using doxycycline on a "test and treat" basis for onchocercias
234 zithromycin, clindamycin, ciprofloxacin, and doxycycline on blood-supplemented Mueller-Hinton agar an
235 After 6 months, we evaluated the effect of doxycycline on CAVD progression by echocardiography, MMP
236 tions may relate to a differential effect of doxycycline on different stages of diabetic retinal dysf
237 efficacy of either long-term treatment with doxycycline or cognitive-behavioral therapy (CBT) in red
238 l cells were then treated with azithromycin, doxycycline, or control medium to determine whether anti
239 ty acid supplements (72/104, 69 %), low-dose doxycycline (oral; 61/100, 61 %), and flaxseed supplemen
240 r and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus.
241 In this study, the efficacy of antibiotics (doxycycline, oxacillin and rifampicin) in preventing Sta
243 opical cyclosporine, topical vitamin A, oral doxycycline, punctal occlusion, or a combination thereof
244 e therapeutic efficacy and compare different doxycycline regimens, evaluated at different times after
245 eCP2 repression by a cardiomyocyte-specific, doxycycline-regulatable transgenic mouse model aggravate
246 ngineered ES cells from WT mice to express a doxycycline-regulated (dox-regulated) shRNA that targets
247 e generated a transgenic mouse with enhanced doxycycline-regulated A1R expression, specifically in fo
249 and contraction using novel reporters and a doxycycline-regulated expression system for RPB1 In effo
251 We found that transgene (Tg) induction by doxycycline removal at weaning led to motor abnormalitie
253 2.9% for minocycline and 34.6% and 34.6% for doxycycline, respectively, and rates of MICs of </=2 mug
255 ome this immediate lethality, we generated a doxycycline-responsive tTA-DNMT1* rescue line and readil
258 DOT1L shRNA, ablating DOT1L expression with doxycycline significantly reduced ODC1 and E2F2 expressi
259 the Nkx2.5+ cardiomyoblasts, we generated a doxycycline suppressible Cre transgenic mouse under the
260 c (Tg) mice with forebrain Camk2a-controlled doxycycline-suppressible expression of a TDP-43 CTF (ami
261 nd epilepsy, we engineered dTg-211 mice with doxycycline-suppressible forebrain overexpression of miR
262 be repressed by steatotic drugs (valproate, doxycycline, tetracycline, and cyclosporin A) in culture
266 ns of HGA but who have a delayed response to doxycycline therapy or negative confirmatory test result
269 Strategies can now be developed that include doxycycline to control onchocerciasis in areas where inf
272 (12 to 13 months after tick inoculation) in doxycycline-treated (28 days; 5 mg/kg, oral, twice daily
275 ryogenesis, none of the nodules removed from doxycycline-treated patients contained microfilariae, an
276 of myocardial injury and oxidative stress in doxycycline-treated piglets compared with controls.
282 the efficacy of 1 g azithromycin with 100 mg doxycycline twice daily (7 days) for the treatment of ur
283 acebo (37.8 [95% CI, 34.3-41.2]; difference, doxycycline vs placebo, -3.0 [97.5% CI, -8.7 to 2.6]; P
288 st Pseudomonas aeruginosa when combined with doxycycline was precisely evaluated utilizing biolumines
290 e amyloid inhibitors (i.e., rifamycin SV and doxycycline), we demonstrate that covalent labeling and
291 ongoing international clinical trials using doxycycline, we studied the efficacy of cyclines against
292 s of enoxacin, bis-enoxacin, alendronate, or doxycycline were administered for 6 weeks after 6 weeks
293 s should have a low threshold for initiating doxycycline whenever treating febrile or potentially sep
295 76N beta2-microglobulin fibrillogenesis than doxycycline with complete abrogation of fibril formation
296 ibility testing interpretive breakpoints for doxycycline with Streptococcus pneumoniae and to reasses
298 modified mice with lung-specific inducible (doxycycline) Wnt-1 expression (CCSP-rtTA x tetO-Wnt1), t
300 rapidly controlled following treatment with doxycycline, yet three years after initiation of the tre
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