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1 g parenchyma independently of priming in the draining lymph node.
2 ell (DC) Ag presentation in the local muscle-draining lymph node.
3 he MHC II(high) mature DCs were found in the draining lymph node.
4 iling of innate immune response genes in the draining lymph node.
5 id drainage of the vaccine components to the draining lymph node.
6 er cells were also readily detectable in the draining lymph node.
7 tract induces strong Th2 priming in the lung draining lymph node.
8 ow precursors, and CCR7 for migration to the draining lymph node.
9 cating viral RNA into dendritic cells in the draining lymph node.
10 ency of T cells and myeloid cells within the draining lymph node.
11 ent passive diffusion of the nanogels to the draining lymph node.
12 tion of renal antigens to CD8 T cells in the draining lymph node.
13 of organ-specific Treg cells in the prostate-draining lymph nodes.
14 significantly attenuated niT cell numbers in draining lymph nodes.
15 s was isolated from tonsils, gut mucosa, and draining lymph nodes.
16 and kinetics, TFH and GC B cell responses in draining lymph nodes.
17 riven recruitment of T-cell oral tissues and draining lymph nodes.
18 ) T cell priming in both the spleen and skin-draining lymph nodes.
19 he rationale for surgical resection of tumor-draining lymph nodes.
20 CD4(+) T cells and plasmablasts in the joint-draining lymph nodes.
21 injection) trafficking of both cell types to draining lymph nodes.
22 gene expression in vivo, particularly within draining lymph nodes.
23 nodes when compared with Tregs from the lung-draining lymph nodes.
24 elevated Th1 and Th17 cell reactivity in the draining lymph nodes.
25 se in the effector CD4(+) T cell response in draining lymph nodes.
26 ion and impaired effector T-cell egress from draining lymph nodes.
27 vant distribution and prolonging activity in draining lymph nodes.
28 tory T cell response in the cornea and local draining lymph nodes.
29 erum and proportion of Th1 and Th17 cells in draining lymph nodes.
30 activated CD4(+) T-cell populations in lung draining lymph nodes.
31 he skin, and IFN-gamma, IL-1beta, and UBD in draining lymph nodes.
32 isseminated from local sites of infection to draining lymph nodes.
33 delivery to antigen presenting cells in the draining lymph nodes.
34 D4(+)(CD25(+))FoxP3(+) T cells in pancreatic draining lymph nodes.
35 gen clearance from the inflamed colon to the draining lymph nodes.
36 endogenous T cells in the uterus and uterine-draining lymph nodes.
37 gnificant reduction in IL-17(+) cells in the draining lymph nodes.
38 e TSLP-induced DC migration potential to the draining lymph nodes.
39 ssociated with reduced neutrophil numbers in draining lymph nodes.
40 serum IgE levels, and by flow cytometry from draining lymph nodes.
41 +) Tcm) cells including retention within the draining lymph nodes.
42 d is constitutively presented in the stomach-draining lymph nodes.
43 s significant numbers of bystander DC in the draining lymph nodes.
44 CD4+ T cell priming does not occur in liver-draining lymph nodes.
45 from peripheral tissues to the paracortex of draining lymph nodes.
46 th reduced IL-17 and IFN-gamma expression in draining lymph nodes.
47 the initiation of the immune response in the draining lymph nodes.
48 ype (WT) OT-I cells that accumulated in skin-draining lymph nodes.
49 nces, especially mycobacteria, in their skin-draining lymph nodes.
50 IL-17(+) gammadelta T cells and DETCs in the draining lymph nodes.
51 uration and migration of resident DCs to the draining lymph nodes.
52 ng by altering the composition of DCs in the draining lymph nodes.
53 autoreactive donor T cells in the pancreatic draining lymph nodes.
54 R T cells occurred only in the regional skin-draining lymph nodes.
55 d malignant L-selectin-negative cells to the draining lymph nodes.
56 nary MCs before leaving the inflamed skin to draining lymph nodes.
57 s as well as Th2-polarized CD4(+) T cells in draining lymph nodes.
58 cell response in the cornea as well as local draining lymph nodes.
59 the vaccine injection site, but not vaccine-draining lymph nodes.
60 tivate antigen-specific CD8 T cells in renal draining lymph nodes.
61 2L(hi)CD44(lo)Foxp3(+) central Treg cells in draining lymph nodes.
62 upregulation of T cell activation markers in draining lymph nodes.
63 g trafficking of antigen-presenting cells to draining lymph nodes.
64 response on the malignancy and the affected draining lymph nodes.
65 cific B cells were detected in local genital draining lymph nodes.
66 he kidney and T cell activation in the renal draining lymph nodes.
67 in tissue, and migrate through lymphatics to draining lymph nodes.
68 f specific B cells to the mesenteric but not draining lymph nodes.
69 IL-1beta expression by myeloid cells in the draining lymph nodes.
70 ad box P3) IFN-gamma(+) T cells in the heart-draining lymph nodes.
71 fibroblastic reticular cell networks in the draining lymph nodes.
72 o t 5, that targets the lung rather than the draining lymph nodes.
73 , and eosinophil infiltration in the stomach-draining lymph nodes.
74 e immune responses at the injection site and draining lymph nodes.
75 from whole nondiseased human lungs and lung-draining lymph nodes.
76 the CNS and meninges to the peripheral (CNS-draining) lymph nodes.
79 AM did not prevent lymphocyte recruitment to draining lymph nodes 24 h after transfer, but it was req
80 s taken up by two distinct DC populations in draining lymph nodes: a mostly CD11c(int)MHC class II (M
81 lts indicate that tumor growth reduces tumor-draining lymph node accumulation and alters the distribu
82 the capacity to robustly expand in the lung-draining lymph node after live influenza virus infection
83 of IL-4-producing TFH cells and TH2 cells in draining lymph nodes after airway exposure to IL-1 famil
85 erentially transport Ag from the lung to the draining lymph node and are crucial for the initiation o
86 s to a delay in CD8 T cell activation in the draining lymph node and hinders the timely appearance of
87 IL-1beta production by myeloid cells in the draining lymph node and served as a strong stimulus for
90 er, lymphocytes were isolated from allograft draining lymph nodes and analysed by flow cytometry.
92 rain predominately by neutrophils in vaccine-draining lymph nodes and by smaller numbers of dendritic
93 ntional DCs that transport tumor antigens to draining lymph nodes and cross-present antigen to activa
94 DCs triggers CCR7-dependent migration to the draining lymph nodes and enhances their capacity to init
95 yD88(-/-)CD4(+) T cells to accumulate in the draining lymph nodes and genital tract when exposed to t
97 on significantly increased Foxp3(+) Tregs in draining lymph nodes and in the spleen but failed to red
98 en caused homing of tumor-infiltrating DC to draining lymph nodes and increased infiltration of T cel
99 complex class II molecules, migrated to the draining lymph nodes and induced an increase in Treg cel
100 ired the emigration of XCR1(+) dermal DCs to draining lymph nodes and occurred irrespective of TLR si
101 gulatory T cells at the graft site and graft-draining lymph nodes and preventing T-cell infiltration.
102 rentially retained at the injection site and draining lymph nodes and produced fewer systemic inflamm
103 immune responses was analyzed by collecting draining lymph nodes and sera and by challenging the ani
104 performed to determine specific intragraft, draining lymph nodes and spleen T-cell population, and s
106 al cellular cytokine response in splenic and draining lymph nodes and the antibody response in serum
107 ion by plasmacytoid DC (pDC) from skin/tumor draining lymph nodes and the cross-priming of Ag-specifi
108 of CCR6(+) Treg cells was also found in the draining lymph nodes and tumor-infiltrating lymphocytes
110 ivation of tumor antigen-specific T cells in draining lymph nodes, and a reduction in regulatory T ce
111 ent in ApoE(-/-)Irf5(-/-) mice in the aorta, draining lymph nodes, and bone marrow cell cultures, ind
112 antigen presenting cell (APC) trafficking to draining lymph nodes, and enhances antigen cross-present
113 mice showed increased levels of MCP-1 in the draining lymph nodes, and in vivo administration of MCP-
114 tracting chemokines, migration of DCs to the draining lymph nodes, and priming of allergen-specific T
115 +)CD80(-) GC B cells in proximal- and distal-draining lymph nodes, and promoted the persistence of GC
117 uency increased significantly in the spleen, draining lymph nodes, and transplanted islets and remain
118 enous and exogenous DCs, migration of DCs to draining lymph nodes, and tumor infiltration of CD4(+) a
120 nstrated that migratory DCs from the stomach-draining lymph nodes are the only DC subset capable of c
121 oducing CD4(+) T cells in muscle tissues and draining lymph nodes as well as reduced parasite burden
122 +) and CD103(+) dendritic cells, in the lung-draining lymph node, as well as increased expression of
123 reduced CD40 expression in DCs isolated from draining lymph nodes at 2 days post infection (dpi).
125 ars not to alter dendritic cell migration to draining lymph nodes but is associated with enhanced flu
128 cer cells tend to metastasize first to tumor-draining lymph nodes, but the mechanisms mediating cance
129 al inflammatory response develops in the paw-draining lymph nodes by an IL-17-dependent mechanism.
132 decreased in the in vitro restimulated skin-draining lymph node cells from the EGF-treated mice.
133 re found in bronchoalveolar lavage fluid and draining lymph node cells of Nur77-KO mice, as well as i
134 sociated with little or no reduction in lung-draining lymph node cells or their cytokine production a
135 led to a similar bias in CD4(+) T cells from draining lymph node cells toward IL-17A and away from IF
136 sue, bronchoalveolar lavage fluid (BALF) and draining lymph node cells were analysed for inflammation
139 ll trafficking, diverting migration from the draining lymph nodes/CNS route to the mesenteric lymph n
140 tially at the injection site and the nearest draining lymph nodes compared with the attenuated varian
141 increased emm1 GAS dissemination locally to draining lymph nodes (controls median 183 CFU per node [
142 us that targets dendritic cells (DCs) in the draining lymph node (DLN) and produces intracellular vir
143 mice, followed by the analysis of lungs and draining lymph node (DLN) cell infiltrates, immunoglobul
148 n vitro but failed to home from the graft to draining lymph nodes (dLN) as efficiently as wild type.
151 ed s.c. shows minimal uptake into lymphatics/draining lymph nodes (dLNs) and instead is rapidly distr
152 d with a lack of iNKT cell activation in the draining lymph nodes (dLNs) and prevented the protective
153 nfection, CD4(+) T cells are expanded in the draining lymph nodes (DLNs) and restimulated in the infe
154 raction of the vaccine dose localized in the draining lymph nodes (dLNs) and the spleen 6h after i.p.
155 with decreased lymphocyte migration into the draining lymph nodes (dLNs) of infected Cd22(-/-) mice.
156 igated virus-host interactions in the rectal draining lymph nodes (dLNs) of rhesus macaques at differ
157 lammation, LAPCs accumulate in the lungs and draining lymph nodes (DLNs), concomitant with the onset
160 a population of monocyte-derived DCs in the draining lymph node, early release of IL-12p70 and IFN-g
163 tivation and migration from the intestine to draining lymph nodes, events necessary for Th2 priming.
165 red into Rag1(-/-) mice proliferated in skin-draining lymph nodes, expressed a restricted T-cell rece
168 of CD4(+) central-memory T cells within the draining lymph nodes following induction of contact hype
169 ed to support a role of macrophage efflux to draining lymph nodes following treatment with infliximab
170 within the interfollicular areas of mucosal draining lymph nodes, forming a distinct microenvironmen
173 nt, activation, and apoptosis of DCs in lung-draining lymph nodes; granulocyte and macrophage infiltr
174 r, the severe loss of dendritic cells in the draining lymph node had no impact on viral replication i
175 on of dermal mast cells from the skin to the draining lymph nodes has a prominent role in activating
176 i) the suppression Th1/Th17 pathways in lung-draining lymph nodes, (iii) the recruitment of effector
177 tion of dendritic cells and T cells into the draining lymph node immediately following infection and
178 causes retention of effector T cells in the draining lymph node in a neuroinflammatory autoimmunity
179 nt, these two DC populations appeared in the draining lymph nodes in comparable numbers and with simi
182 regs), which are induced locally in the skin-draining lymph nodes in response to UVB exposure, connec
183 dies have highlighted the importance of lung-draining lymph nodes in the respiratory allergic immune
185 +) pulmonary dendritic cells in the lung and draining lymph nodes in wild-type BALB/c mice after RSV
187 aerobic bacteria from the neonatal gut into draining lymph nodes, including the opportunistic pathog
188 n increase in donor cells in the mediastinal draining lymph nodes; increased lymphatic vessel area; a
189 ry changes either in the lung or in the lung draining lymph nodes (LDLN), pretreatment of blood eosin
190 mour antigens to antigen-presenting cells in draining lymph nodes, leading to increased surface prese
191 by myeloid-derived suppressor cells in tumor-draining lymph nodes, leading to T cell responses skewed
192 ing of these antigen-presenting cells to the draining lymph node (LN), it was shown that the iron oxi
195 demonstrate in this study that Tregs in the draining lymph nodes (LN) of allograft acceptors, but no
196 ans cells are APCs that migrate from skin to draining lymph nodes (LN) to drive peripheral tolerance
197 pecific cells underwent several divisions in draining lymph nodes (LN; DLNs) while maintaining expres
198 d presentation of antigen to T cells in skin draining lymph nodes (LNs) both 3 and 10days after admin
200 econd population migrated from the skin into draining lymph nodes (LNs) in a CCR7-dependent manner.
203 rease in Treg percentages in aorta and aorta-draining lymph nodes (LNs) of these mice compared with a
204 cells and germinal center (GC) B cells from draining lymph nodes (LNs) than the parent virus rLBNSE.
205 c T cell responses are initiated in the lung draining lymph nodes (LNs), and lymphocytes subsequently
206 f natural and peripheral Tregs in spleen and draining lymph nodes (LNs), elevated IL-10 and TGF-beta
211 accumulation of slanDCs in metastatic tumour-draining lymph nodes (M-TDLN) from carcinoma patients.
213 lated from tumor-infiltrating lymphocytes or draining lymph nodes maintained similar phenotypic and s
214 ice with PIN lesions exhibited metastases to draining lymph nodes, marked by relatively differentiate
215 t of SIV from penile mucosal surfaces to the draining lymph nodes may allow an HIV vaccine that produ
216 Interestingly, tumor-infiltrating and tumor-draining lymph node NK cells displayed an upregulated ex
217 lungs (including the major blood vessels and draining lymph nodes) obtained en bloc from 72 individua
219 ntional effector T cells were collected from draining lymph nodes of allogeneic or syngeneic corneal
220 onstrate that although lymphocytes from skin-draining lymph nodes of autoimmune-prone MRL/MpJ-Fas(lpr
221 solated CD4(+) T cells from the upper airway draining lymph nodes of both OVA323-339- and MPO409-428-
223 B cells were induced at higher levels in the draining lymph nodes of CD47KO mice compared to those in
224 xtended monitoring of IDO(+) DC in the tumor-draining lymph nodes of IL-12 plus GM-CSF-treated tumor-
225 CXCL13 levels correlated with GC activity in draining lymph nodes of immunized mice, immunized macaqu
226 ved instead from influenza virus in the lung-draining lymph nodes of infected mice, they proliferated
227 migratory dermal dendritic cells in the skin-draining lymph nodes of L. donovani-infected malnourishe
229 Upon analysis of microRNA (miR) profile in draining lymph nodes of mice with DTH, treatment with I3
232 -secreting virus-specific CD4 T cells in the draining lymph nodes of NK1R(-/-) mice was much higher t
234 ntly, CD31-conditioned DCs purified from the draining lymph nodes of ovalbumin-immunized mice favored
236 ion of MOG35-55-specific T cells in the skin draining lymph nodes of primed mice, but it is not requi
238 otein expression were higher in T cells from draining lymph nodes (P = 0.03 and P = 0.04, respectivel
239 es of CD4(+)Foxp3(+) T cells in the pancreas-draining lymph nodes, pancreas, and peripheral blood of
240 und in histopathologically negative prostate draining lymph nodes (PDLN) in mice harboring oncogene-d
241 D8(+) and/or CD103(+) dendritic cells in the draining lymph node played a critical role in the primin
242 mal mast cell migration from the skin to the draining lymph nodes plays a prominent role in activatin
243 om peripheral blood (PB) and from pancreatic draining lymph nodes (PLN) of T1D patients and non-diabe
244 transiently at the muscle injection site and draining lymph node postinjection, consistent with the r
245 g RPM we find that high endothelial cells in draining lymph nodes rapidly increase translation in the
247 g kinetics in IL-12-treated tumors and tumor-draining lymph nodes revealed a transient loss followed
248 is of CD11c(+)MHC-II(hi) DCs in the lung and draining lymph nodes revealed that allergen exposure inc
249 4+ T cell hyporesponsiveness within the skin-draining lymph nodes (sdLN), manifested as reduced CD4+
250 R-signaled DCs required their homing in skin-draining lymph nodes (sDLNs) where they induced inflamma
252 under steady-state conditions, ILCs in skin-draining lymph nodes (sLNs) were continuously activated
253 ased numbers of migratory dendritic cells in draining lymph nodes, specifically dendritic cells with
254 creased the numbers and percentage of Tregs (draining lymph node, spleen), which resulted in reduced
255 for 105 days by size measurements, and skin, draining lymph node, spleen, and sera were investigated
256 maturation and plasma cell responses in the draining lymph nodes, spleen, and bone marrow and confer
257 ficant reductions in bacterial burden in the draining lymph nodes, spleen, and liver were observed.
259 to secondary sites of infection, mainly the draining lymph nodes, spleen, gastrointestinal tract, an
260 ime dependent changes in RNA profiles of the draining lymph node, suggesting a change in cell profile
261 Although STING also induced IDO in tumor-draining lymph nodes (TDLN) during EL4 thymoma growth, t
263 g responses, which quickly manifest in tumor-draining lymph nodes (TDLNs) after tumor inoculation and
265 skin infection by restoring DC migration to draining lymph nodes, Th17 differentiation, and increase
266 gammadelta T cells in the infected foot and draining lymph node that was associated with the product
267 differential distribution of exosomes in the draining lymph nodes that is dependent on the lymphatic
268 th appropriate Ag specificity are present in draining lymph nodes, they are conspicuously absent from
269 pression of CD86 and rapidly migrated to the draining lymph node to become the most abundant skin-der
270 r phenotype that allows trafficking from the draining lymph node to the lungs and, thereby, prevented
271 lung during inflammation and migrated to the draining lymph nodes to boost TH2-mediated effector resp
272 ouse MB49 bladder tumors, spleens, and tumor-draining lymph nodes to identify patterns of anti-tumor
274 nd migrate out of the skin and mucosa to the draining lymph nodes to present antigens to T and B cell
278 sition in peripheral tissues, DCs migrate to draining lymph nodes via the lymphatics to present antig
280 ith pBCG or rBCG, and gene expression in the draining lymph nodes was analyzed by microarray at day 1
283 atory agents, the hypertrophy induced in the draining lymph nodes was minimal and significantly less
284 lymphocytes expressing RANKL in the cervical draining lymph nodes were higher in IL-33-treated P. gin
285 nced suppressive capacity of Tregs from skin-draining lymph nodes when compared with Tregs from the l
286 tive and cytokine-producing potential in the draining lymph nodes, when the animals were challenged 2
287 n of activated lung dendritic cells into the draining lymph node where they primed naive T cells to d
289 s) are professional APCs that traffic to the draining lymph nodes where they present processed antige
290 gene-expressing melanocytes localize to skin-draining lymph nodes, where they induce T-cell prolifera
291 airment is limited to the lungs and the lung-draining lymph nodes, where viral Ags are unusually pers
292 s in the paws and in Th17 lymphocytes in the draining lymph nodes, whereas T-regulatory cells were da
293 rly proinflammatory cytokine response in the draining lymph node, which impacts immunity and control
294 ping the early innate immune response in the draining lymph node, which impacts the spread of virus i
295 leukocytes found in primary tumors or tumor-draining lymph nodes, which included mainly CD14(+) mono
296 ciency results in increased T cell egress to draining lymph nodes, which is associated with impaired
297 eased lymphatic flow from the donor graft to draining lymph nodes, which may be a factor in promoting
298 7BL/6 mice enhanced resident DC migration to draining lymph nodes, which was verified by imaging lymp
299 focused the in vivo immune activation on the draining lymph nodes while dramatically reducing systemi
300 inhibited Th1 and Th17 and amplified Treg in draining lymph nodes, while reducing dry eye pathogenesi
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