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2 ern societies, we still need to anticipate a dramatic absolute increase in dementia occurrence over t
4 ions of acidic residues in the palm induce a dramatic acceleration of desensitization followed by the
5 transcriptional changes and highlighted the dramatic acceleration of development in the fovea compar
6 Au)-based photocatalyst (PC) has led to the dramatic acceleration of known TM-catalyzed reactions, a
7 on of NMDA receptors (NMDARs) resulting in a dramatic acceleration of NMDAR-mediated synaptic current
8 gly, we revealed that HFD-fed mice display a dramatic accumulation of hepatic BMP compared to chow-fe
9 increase of mitochondrial translocases and a dramatic accumulation of the mitochondrial DNA replicati
10 ly shows that SpoIIIAG exhibits a unique and dramatic adaptation of the RBM fold with a unique beta-t
13 derlying why peer rejection may lead to more dramatic alterations in self-views during adolescence th
14 ique lipids across 21 lipid subclasses, with dramatic alterations in the lipidome across developmenta
16 the Great Salt Lake in late 2013 documented dramatic alterations in the system in response to the el
17 thdrawal from repeated cocaine also produces dramatic alterations in the transcriptome of NAc MSNs, b
19 of the MiSeq-derived 16S rRNA data revealed dramatic and differential shifts in the oil-amended comm
20 urological injuries and diseases all exhibit dramatic and dynamic changes to the host microenvironmen
21 Although morphine and other opioids offer dramatic and impressive relief of pain, their impact is
22 ever been exposed to serum, we demonstrate a dramatic and lasting change in phagocytic capacity after
25 licited taste activity at adulthood produced dramatic and selective reorganization of terminal fields
26 both the brain and spinal cord also produced dramatic and synergistic improvements in motor function
27 now exists and what is still needed to bring dramatic and tangible change to patients.-Scolnick, E.
29 f supercooled water under pressure, in which dramatic anomalies are expected based on interpolation b
30 reduction in conventional DC frequency and a dramatic (approximately 80%) reduction in atherosclerosi
31 feat stress resulted in repeated episodes of dramatic behavioral changes from hyperactivity to "depre
32 h BH4 and/or neurotransmitter precursors had dramatic beneficial effects and resulted in the preventi
36 ng keto-carotenoids, which excitation causes dramatic but fully reversible rearrangements of the OCP
37 trated that MeV engagement of SLAMF1 induces dramatic but transient morphological changes, most promi
38 alysis of motor cortical activity revealed a dramatic change between behaviors in the coordination of
39 nge in body shape was preceded by an equally dramatic change in sensory abilities akin to transitioni
40 distortion of the protein blue Cu site and a dramatic change in the charge transport regime of the si
42 that strong electron-phonon coupling and its dramatic change should be incorporated into or reconcile
43 erahertz microscopy, we find that there is a dramatic change to the vibrational directionality with i
44 ally silenced during retinogenesis, the most dramatic change was derepression of cell-type-specific d
47 -related loss of tissue homeostasis, despite dramatic changes in mitochondrial ultrastructure and mit
49 at valence fluctuations of YbAl3 can lead to dramatic changes in the Fermi surface topology in recipr
50 e show that valence fluctuations can lead to dramatic changes in the Fermi surface topology, even res
55 tment of acute ischemic stroke has undergone dramatic changes recently subsequent to the demonstrated
59 here over the past two decades has witnessed dramatic changes, with continuous improvement in develop
60 eps to deeply understand the drivers of such dramatic changes: (i) describe fundamental demographic r
61 l pumping of a symmetric resonator enables a dramatic chiral cooling of clockwise and counterclockwis
66 ng these checkpoints on T cells has provided dramatic clinical benefit, but only a subset of patients
68 y can be conducted in aqueous solution where dramatic colorimetric and fluorescence changes are easil
71 ding mode requires H-bonding to Ser119 and a dramatic conformational switch in the F-G fragment, whic
72 on ecosystem processes, whereas others have dramatic consequences for human and ecosystem health.
74 ated voltage sensor conformation, leading to dramatic deceleration of current and fluorescence deacti
75 population to outbreak levels, followed by a dramatic decline - have been associated with biological
76 cular atresia, reduced ovulation rate, and a dramatic decline in fertility is observed in alpha-SNAP-
77 o severe heat stress, as indicated by a more dramatic decline of the maximum efficiency of PSII and l
78 sing vaccination and development have led to dramatic declines in the global burden of measles, but t
81 Histone phosphorylation by M6CK results in a dramatic decrease in methylation of arginines adjacent t
84 influence of experience on tempo but also a dramatic decrease in the influence of genetics, indicati
85 owever, inhibiting both sEH and COX led to a dramatic decrease in tumor growth, suggesting that the c
86 globin concentration change, together with a dramatic decrease of the beta band power, happened sever
87 alpha,beta-dialkylvinyl substrates, while a dramatic decrease on enantioselectivity was observed in
88 rsus all controls, which was associated with dramatic decreases in beta-catenin targets and some K-Ra
89 CD73 expression in cultured IECs resulted in dramatic defects in intraepithelial localization and rep
90 ial contact with the erythrocyte followed by dramatic deformations linked to the function of the Eryt
92 tant pulse widths can be generated without a dramatic degradation of beam quality within a broad rang
94 d low amounts of large-scale deletions and a dramatic depletion of mtDNA in the epidermis and showed
96 The long arm of Chromosome 4 underwent a dramatic developmentally regulated switch to late replic
98 des and all their modified forms, uncovering dramatic differences in modification rates across experi
102 al extent of Erk pathway activation leads to dramatic disruptions of patterning and morphogenesis.
103 pression during in vitro adipogenesis causes dramatic downregulation of Ppargamma2 expression as well
105 antibiotic prescription rate for ARTI and a dramatic drop in broad-spectrum antibiotic prescriptions
106 n these reactions has been found to effect a dramatic drop in reaction temperature (to room temperatu
107 een E17.5 and E18.5 dyW-/- muscles display a dramatic drop in the number of Pax7- and myogenin-positi
109 ity using specific inhibitors revealed quite dramatic effect on condensation of chromatin and chromos
111 stream analysis methods selection can have a dramatic effect on the accuracy of taxonomic classificat
112 t the conformation of the Met(20) loop has a dramatic effect on the ordering of active site hydration
113 ero-dimensional to three-dimensional, with a dramatic effect on the properties of each compound.
114 attacking low molecular-weight thiol have a dramatic effect on the protein's mechanical stability.
118 es with these radiolabeling handles can have dramatic effects on important properties such as particl
121 d changes in timing of reproduction can have dramatic effects upon the success of fish populations an
123 change in the circumpolar region is causing dramatic environmental change that is increasing the vul
126 nvironments to marine ones, concomitant with dramatic evolutionary transformations documented in thei
128 urring mutator bacterial pathogen provides a dramatic example of the potential impact of pathogen evo
129 c ablation of the Roquin paralogs leads to a dramatic expansion of NKT17 cells, whereas peripheral ma
130 there was some correlation between observed dramatic fluctuations in the gut microbiome and intensif
131 n Andean maize, which has experienced a more dramatic founder event compared to other maize populatio
133 lence of transposons in the maize genome and dramatic genomic variation driven by transposons, we hyp
135 tion of genes in metabolic pathways and more dramatic glycolytic responses to hormonal stimulation.
138 d charge-delocalizing interactions lead to a dramatic (>hundred-billion-fold) acceleration, but the e
141 poral extent of surveillance data can have a dramatic impact on inferences about population processes
144 nce control in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.
148 nes were combined into a harmonic complex, a dramatic improvement in discrimination ability was obser
149 t reduced in BCAAs was also accompanied by a dramatic improvement in glucose tolerance and insulin re
152 ses in modified aptamers has recently led to dramatic improvement in the success rate of identifying
155 changes in relative transcript counts led to dramatic improvements in accuracy compared to normalized
156 xpressing Cas9 in the germline, resulting in dramatic improvements in both the consistency and effici
158 kingly, an EcAGPase-R130A mutant displayed a dramatic increase in activity when compared with wild-ty
160 nce of palmitoylation results in part from a dramatic increase in ARL13b stability, which is not obse
161 Dense particulate suspensions exhibit a dramatic increase in average viscosity above a critical,
165 jection into the GF interneuron results in a dramatic increase in dye uptake in neurons lacking FMRP.
166 in from an autoinhibited state, leading to a dramatic increase in fast, processive dynein motility.
167 er the arrest of B lymphopoiesis and found a dramatic increase in fat, increased CD11b(+) myeloid cel
168 f food allergy do not adequately explain the dramatic increase in food allergy in Western countries.
170 tment with either DAC or DAC+KDM5i induced a dramatic increase in H3K27ac at enhancers with an associ
173 ON, real-time noninvasive imaging revealed a dramatic increase in leukocyte rolling and adhesion in v
174 ese HiMyc mice at 6 months of age revealed a dramatic increase in mRNAs encoding various chemokines,
175 highly expressed, the lack of APP leads to a dramatic increase in plasma membrane recruitment of endo
178 day and 3-week old dyW-/- mice demonstrate a dramatic increase in pSTAT3 relative to WT muscles.
180 site via fractalkine delivery resulted in a dramatic increase in regeneration as evident from histol
181 by IL-1beta-expressing cancer cells showed a dramatic increase in S100A4, COX-2 and the alteration of
183 and computational improvements have led to a dramatic increase in the number of viral genome sequence
184 d inflammatory conditions have resulted in a dramatic increase in the population of immunosuppressed
187 peptide (HBcAg/p21) synthesis, it mediates a dramatic increase in viral capsid production and robust
188 ure-dependent ESR measurements demonstrate a dramatic increase of both the apparent barrier and the r
189 c envelopment of VZV capsids, resulting in a dramatic increase of envelope-defective particles and a
190 in the mixotrophic mode, concomitant with a dramatic increase of PII phosphorylation that senses car
192 kdown of neuroligins, respectively, causes a dramatic increase or decrease in synapse density, wherea
193 des of decreasing scarlet fever incidence, a dramatic increase was seen in England beginning in 2014.
194 which Ser367 of PS1 was mutated to Ala, show dramatic increases in Abeta peptide and in betaCTF level
196 n of secreted Abeta40 or Abeta42 resulted in dramatic induction of drusen-like deposits by 2 months'
198 Additionally, the study of CTCs has exposed dramatic intrapatient and interpatient heterogeneity and
199 lar cells with the Au electrode experience a dramatic, irreversible efficiency loss, rendering them e
201 The domestic dog represents one of the most dramatic long-term evolutionary experiments undertaken b
203 ality of both CRF01_AE Envs as measured by a dramatic loss in infectivity and ability to mediate cell
205 rmittivity at the interface, and explain the dramatic loss of electron mobility with back-gate deplet
210 Neolithic/Bronze Age, however, we estimate a dramatic male bias, with approximately five to 14 migrat
212 To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT midline
214 scle-type specific, short-duration SF caused dramatic molecular changes to shoulder muscles and respo
215 The vertebrate embryo undergoes a series of dramatic morphological changes as the body extends to fo
216 t requirements and molecular drivers for the dramatic morphological transformation platelets undergo
218 ital muscular dystrophy type 1A (MDC1A) is a dramatic neuromuscular disease in which crippling muscle
219 and canonical autophagy blockade, results in dramatic nuclear pathology with disruption of the nuclea
220 light irradiation: (1)O2 triggering induced dramatic particle size expansion due to the conversion o
223 ls, however, G1-expressing cells showed more dramatic phenotypes, resembling those observed in cultur
224 ny other organisms, Symbiodinium can undergo dramatic physiological changes that are not reflected by
225 a-synuclein; all three systems demonstrate a dramatic preference of the on-surface aggregation pathwa
228 strated that Kir2.1-52V is associated with a dramatic prolongation of action potential duration with
230 well-defined uniform polarization display a dramatic range of edge softness depending on the orienta
231 emperate alpine organisms likely experienced dramatic range shifts, given that much of their habitat
235 electron microscopy structure indicates that dramatic rearrangement of the C-terminal region of Nop15
237 massive endosomal influx was accompanied by dramatic recruitment of the intracellular SphK1 and Bin/
238 nduced by UCP1 deletion is associated with a dramatic reduction in electron transport chain abundance
239 the single channel level, UBP684 produced a dramatic reduction in long shut times and a robust incre
241 acer uptake by the thyroid, accompanied by a dramatic reduction in NIS protein expression in this tis
244 in enzymatic activities were not driven by a dramatic reduction in the abundance of supercomplexes.
248 allenge in HDM-sensitized mice resulted in a dramatic reduction of allergic response, indicating the
249 regulation induces apoptosis together with a dramatic reduction of cell growth and colony formation.
250 to engineer a mouse mutation, but observe a dramatic reduction of LoxP recombination in mice that in
252 tubule of TAR2 (tyrR, CG7431) resulted in a dramatic reduction, but not elimination, of the TA-media
253 ce, which have ADAM10 deleted from DCs, have dramatic reductions in IgE production and do not develop
254 iven at high frequency (> 20 Hz) resulted in dramatic reductions in short-term facilitation and, at t
255 the same macroecological patterns explaining dramatic regional catch differences in the contemporary
256 ling endosomes and MYO6+ expression causes a dramatic relocalization and clustering of this endocytic
258 f mitochondrial bioenergetics is followed by dramatic reorganization of the chondriome (all mitochond
259 other eukaryotes, S. cerevisiae undergoes a dramatic reprogramming of gene expression during meiosis
260 ve PC by means of PET and SPECT as well as a dramatic response of metastatic castration-resistant PC
263 al reprogramming, the S84D mutant displays a dramatic reversal of beta-elimination substrate specific
264 ablished in migration mutants, in spite of a dramatic rostrocaudal repositioning of these neurons in
267 down, the host red cell undergoes an abrupt, dramatic shape change due to the sudden breakdown of the
270 the peripheral nervous system (PNS) causes a dramatic shift in SC molecular phenotype and the generat
272 protecting cell identity, and in controlling dramatic shifts in cell-wide gene expression through inh
274 tion, intense pulses of light can experience dramatic spectral broadening when propagating through le
275 y to design ratiometric sensors that display dramatic spectral shifts by leveraging the chemoselectiv
276 d silver signal is translated rapidly into a dramatic speed change associated with the enhanced catal
277 Scattering angular distributions showed a dramatic stereodynamic preference ( 3:1) for perpendicul
278 evealed that the binding of c-di-GMP induces dramatic structural changes in MapZ that are crucial for
279 In the last ten years, there has been a dramatic surge in the number of publications where singl
282 he single mutants were similarly impaired, a dramatic synergistic effect was found for the double mut
284 in South Center Lake that were followed by a dramatic temporal shift in population genetic structure
286 ncrease in hydrogen mobility above 265 K, so dramatic that it can be viewed as melting of hydrogen su
287 ory bowel disease (IBD), as evidenced by the dramatic therapeutic responses in Crohn's disease (CD) p
288 ges in situ, we report polymers that undergo dramatic topological transformations via a process we te
290 to nuclear RNA targets was accompanied by a dramatic translocation of Hnrnpa1 and other pre-mRNA spl
294 f the FETUA gene in BALB/c mice results in a dramatic upregulation of airway hyperresponsiveness, lun
295 R-ligand responsiveness, as illustrated by a dramatic upregulation of CD83, CD86, and MHC class I in
296 his induced responsiveness is accompanied by dramatic upregulation of IL-7Ralpha on DCs with little c
298 ed by Abs in Rag1(-/-) mice, the mice showed dramatic weight loss and ZIKV infection in the brain and
299 ments in granularity and range are even more dramatic when the discrimination between the classes is
300 ntroduction of the central BN core induces a dramatic widening of the HOMO-LUMO gap and an enhancemen
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