ライフサイエンスコーパス: dramatic change

1 d DKD glomeruli, and PLK2 exhibited the most dramatic change.

2 This focus is about to undergo a dramatic change.

3 otein filaments, with G151D showing the most dramatic changes.

4 pe B aortic dissection (ATBAD) is undergoing dramatic changes.

5 ic health provision in England is undergoing dramatic changes.

6 contrast of gray and white matter undergoes dramatic changes.

7 The most dramatic changes (1711 transcripts up- and 3242 down-reg

8 Extracellular matrix undergoes dramatic changes after MI and therefore might be linked

9 cortex matures late in development, showing dramatic changes after puberty onset, yet few experiment

10 Dramatic changes also were seen in the chromatin, with a

11 L-C levels among all patients, with the most dramatic change among patients with the worst disease co

12 As the global population urbanizes, dramatic changes are expected in city lighting and the u

13 es, intron length and PATC-character undergo dramatic changes as orthologs move from active to repres

14 alysis of motor cortical activity revealed a dramatic change between behaviors in the coordination of

15 n a ferromagnet, its spin moment undergoes a dramatic change, but how it works remains a mystery.

16 However, these synapses undergo dramatic change during aging.

17 a different embryologic origin, undergoes a dramatic change during the transition from the fetal to

18 The AMPA receptors also exhibited dramatic changes during cortical development with signif

19 stromal extracellular matrix (ECM) undergoes dramatic changes during development and in tumorigenesis

20 rotubule organization, both of which undergo dramatic changes during erythroblast enucleation.

21 in and nuclear pore complexes (NPCs) undergo dramatic changes during mitosis, which in vertebrates an

22 gulation of myosin isoforms did not show any dramatic changes during the observation period.

23 e ancestral XIC sequences show that the most dramatic changes during the past 80 million years occurr

24 Brain structure and function experience dramatic changes from embryonic to postnatal development

25 Dramatic changes have occurred in the Arctic Ocean over

26 eps to deeply understand the drivers of such dramatic changes: (i) describe fundamental demographic r

27 h of the replication initiation sites, but a dramatic change in (CTG)(n) .

28 Surprisingly, there was no dramatic change in activity profile with respect to age

29 However, a dramatic change in basins of attraction is induced by ve

30 The molecular basis of this dramatic change in behavior upon introduction of the V(6

31 erular disease, podocyte injury results in a dramatic change in cell morphology known as foot process

32 ssion downstream of miR200 also results in a dramatic change in cell morphology resembling that of a

33 ultures to the dark, which correlated with a dramatic change in cell surface morphology, likely refle

34 ellular matrix of CP cells, which leads to a dramatic change in cellular morphology.

35 H > 6 to +6 at pH = 2.5, suggesting that the dramatic change in charge on each monomer may drive diss

36 The dramatic change in color of these compounds from red (3,

37 congenital heart defect has undergone a more dramatic change in diagnostic approach, management, and

38 0 My after the extinction, and resulted in a dramatic change in faunal composition.

39 (all P > .01) representation, suggesting no dramatic change in future representation as practicing p

40 This dramatic change in laminar and cellular labeling is inde

41 The dramatic change in membrane bending stiffness in the pre

42 With the exception of the less dramatic change in occluded site size, the behavior of D

43 and this replication process brings about a dramatic change in optical properties of the sample-a ch

44 sharply reduced dentinal tubules; and (5) a dramatic change in Osx and nestin expression.

45 These approaches overlook the dramatic change in our understanding of life's diversity

46 The past decade has seen a dramatic change in our understanding of the role of the

47 ated SC and PP input to CA1 is signaled by a dramatic change in output mode and an increase in input

48 The dramatic change in phenotype associated with transdiffer

49 e humoral immune response, B cells undergo a dramatic change in phenotype to enable antibody affinity

50 high temperature (28 degrees C) results in a dramatic change in plant development.

51 s (271.15 K and 272.15 K), as shown from the dramatic change in Raman spectra and fluctuations in AL/

52 nge in body shape was preceded by an equally dramatic change in sensory abilities akin to transitioni

53 ntrol of interfacial interactions leads to a dramatic change in shape and morphology for particles ba

54 opposing sides of the neural folds undergo a dramatic change in shape to protrude from the epithelial

55 The most dramatic change in specificity resulted from substitutio

56 rom deformation-related structures, with the dramatic change in splitting parameters into the rift ax

57 To address the effect of dramatic change in temperature and viscosity during PCR

58 ned upon deletion of the 7-propionate, but a dramatic change in the 7-propionate carboxylate (13)C ch

59 Thus, ICOS strongly contributed to the dramatic change in the balance between Ag-specific Teff

60 ernative equilibria remains constant but the dramatic change in the basins does not arise from subtle

61 Several recent studies have shown a dramatic change in the behavior of flagellated bacteria

62 distortion of the protein blue Cu site and a dramatic change in the charge transport regime of the si

63 Exercise stimulates a dramatic change in the concentration of circulating horm

64 ow the temperature T( *) = 6.5 K, there is a dramatic change in the elastic scattering lineshape acco

65 This leads to a dramatic change in the extent of activated cullin-RING u

66 oval of local populations should result in a dramatic change in the flux, and possibly species compos

67 There is, however, a dramatic change in the form of the gap anisotropy with r

68 The dramatic change in the geographic patterns of heart dise

69 The transition is driven by a dramatic change in the interactions among Ir 5d orbitals

70 This dramatic change in the interfacial tension enables a var

71 ancer therapeutics has undergone a rapid and dramatic change in the last few years.

72 katanin regulatory subunit in turn caused a dramatic change in the microtubule-binding properties of

73 Cs in vivo after chemotherapy, identifying a dramatic change in the physiology of primitive AML cells

74 der a bifunctional organocatalyst provokes a dramatic change in the regioselectivity, from the 1,5- t

75 Surprisingly, binding of S8 leads to a dramatic change in the RNA conformation that restores th

76 Single-crystal X-ray diffraction reveals a dramatic change in the solid-state arrangement with exch

77 alkyl-functionalized surfaces that reveal a dramatic change in the surfaces' hydrophobic interaction

78 This dramatic change in the three-dimension configuration of

79 and has stimulated optimism for achieving a dramatic change in the trajectory of the HIV epidemic.

80 In the past decade, we have witnessed a dramatic change in the treatment paradigms due to the de

81 de/resolvation behavior is accompanied by a dramatic change in their magnetic properties: The dihydr

82 cells phagocytosed by macrophages undergo a dramatic change in their metabolism in which amino acids

83 e nucleotide-binding domains that involves a dramatic change in their relative orientation.

84 , and recruited dendritic cells all showed a dramatic change in their resolution signature following

85 m levels, FCVA-deposited carbon films show a dramatic change in their structure in terms of loss of s

86 hat in yeast, centromeric plasmids undergo a dramatic change in their topology as the cells pass thro

87 opically expressing 90 CGG repeats exhibit a dramatic change in their translational profile even prio

88 zes with loss of APC activity resulting in a dramatic change in tumor multiplicity, size, morphology

89 The spliceosome undergoes dramatic changes in a splicing cycle.

90 ns falling within the Abeta sequence lead to dramatic changes in aggregation kinetics and influence t

91 icate that certain prion strains can undergo dramatic changes in biological properties that are not d

92 Among the most dramatic changes in both sexes were a decrease in concen

93 the aromatase inhibitor formestane exhibited dramatic changes in brain miRNA patterns, suggesting tha

94 Dramatic changes in cell and nuclear size occur during d

95 These dramatic changes in cell morphology depend on the auto-p

96 an increase in the rigidity of the bilayer, dramatic changes in cell motility, and subsequent cell d

97 asma capsulatum, are soil fungi that undergo dramatic changes in cell shape and virulence gene expres

98 tion to the actin cytoskeleton, resulting in dramatic changes in cell shape, notably the formation of

99 toward different phenotypes in vitro exhibit dramatic changes in cell shape: M2 cells exhibit an elon

100 of complex structures after injury requires dramatic changes in cellular behavior.

101 virus nonstructural protein 4 (NSP4) induces dramatic changes in cellular calcium homeostasis.

102 ntial is beneficial to overall organ health, dramatic changes in cellular identity can have disastrou

103 ependent activation of naive T cells induces dramatic changes in cellular metabolism that are essenti

104 ble, and T-cell activation is accompanied by dramatic changes in cellular metabolism.

105 ct alterations in mitochondrial networks and dramatic changes in cellular morphology related to cofil

106 Expression of Nesp4 is associated with dramatic changes in cellular organization involving relo

107 Pollen grains undergo dramatic changes in cellular water potential as they del

108 The mutations p.A749G and p.G407R caused dramatic changes in channel gating by shifting (~15 mV)

109 germline in a process that is accompanied by dramatic changes in chromatin modifications.

110 sity in glucose-rich conditions, and undergo dramatic changes in chromatin status after glucose deple

111 Cellular senescence is accompanied by dramatic changes in chromatin structure and gene express

112 Dramatic changes in chromatin structure and histone modi

113 how oscillations in Cdk1 activity drive the dramatic changes in chromosome and spindle dynamics that

114 There were dramatic changes in cytoskeletal protein levels, with ac

115 Dramatic changes in dietary fat intake (-61%; P<0.001 ve

116 These studies revealed dramatic changes in diffusion coefficient and the degree

117 that incorporates a reversible reaction, and dramatic changes in dynamics with small modifications in

118 y of life, development is rapid and includes dramatic changes in eating behavior.

119 We show that dramatic changes in electrochemical stiffness occur due

120 balance between competing phases, leading to dramatic changes in electronic and magnetic properties.

121 Dramatic changes in exposure of a repressive chromatin m

122 brain undergoes protracted development, with dramatic changes in expression and regulation of emotion

123 uring interaction with endobacteria revealed dramatic changes in expression of lipid metabolic genes

124 eta-catenin in the embryonic ectoderm causes dramatic changes in facial morphology.

125 that in FL, spatial organization results in dramatic changes in FL biology, including gene expressio

126 tching, extensive epidermal hyperplasia, and dramatic changes in gene expression in sensory neurons a

127 Cellular transitions require dramatic changes in gene expression that are supported b

128 y response in human cells involves rapid and dramatic changes in gene expression, and the Bru-Seq and

129 hich induces genetic instability, results in dramatic changes in gene expression, resembling changes

130 Axon injury triggers dramatic changes in gene expression.

131 ith ectopic overexpression of miR-203 showed dramatic changes in gene networks related to cell cycle

132 ing characteristics in COS-7 cells, and show dramatic changes in glycosylphosphatidylinositol (GPI)-a

133 . aureus, but not S. aureus Deltapsm, we saw dramatic changes in gross pathology, as well as systemic

134 bits an unstable environment and must endure dramatic changes in habitat chemistry.

135 Bone marrow neuropathy results in dramatic changes in hematopoiesis that lead to microvasc

136 The most dramatic changes in heme conformation occurred in the O2

137 Brain death induces dramatic changes in hemodynamics.

138 ds, favors its own transmission by producing dramatic changes in host reproduction.

139 ughout infection, pathogenic bacteria induce dramatic changes in host transcriptional repertoires.

140 t 2500 years, when the Black Sea experienced dramatic changes in hydrologic and nutrient regimes.

141 Despite dramatic changes in IMTG content on both chow and high-f

142 These transitions include dramatic changes in intestinal contents and require appr

143 hydrocarbon electronic polarizability causes dramatic changes in ion solvation free energy, as well a

144 ion at the centrosome that is accompanied by dramatic changes in its phosphorylation state.

145 flammatory disorder as well as detailing the dramatic changes in its treatment.

146 All three FSS mutations show dramatic changes in kinetic properties, most notably the

147 1 AND 2) transcription factors, resulting in dramatic changes in leaf morphogenesis and increased sus

148 orter inflorescences with fewer flowers, and dramatic changes in leaf shape and complexity.

149 Given the dramatic changes in lifestyles and disease patterns that

150 ular chaperone, which couples ATP binding to dramatic changes in local structure required for protein

151 ibitors of recombinant LSD1 but that produce dramatic changes in methylation at the histone 3 lysine

152 These events include dramatic changes in mitochondrial genome content and org

153 -related loss of tissue homeostasis, despite dramatic changes in mitochondrial ultrastructure and mit

154 Dramatic changes in molecular structure, degradation pat

155 hen all virions are in the postfusion state, dramatic changes in morphology are apparent: elongated p

156 Differentiating erythroid cells undergo dramatic changes in morphology, with reduction in cell s

157 s of chromatin are believed to contribute to dramatic changes in neuronal circuitry.

158 uggest a mechanistic basis for achieving the dramatic changes in organelle positioning seen during ce

159 ffordable Care Act (ACA) of 2010 implemented dramatic changes in our health care system.

160 localization pathways as necessitated by the dramatic changes in ovarian physiology that occur during

161 Especially dramatic changes in overt rhythms and morphology occur d

162 tion to control malaria results in rapid and dramatic changes in parasite population genomics.

163 cond- or subsequent line therapy resulted in dramatic changes in patterns of failure, was well tolera

164 Sudden and dramatic changes in perception occur when prior knowledg

165 Studies in altricial rodents attribute dramatic changes in perinatal cardiomyocyte growth, matu

166 al and sympodial herbaceous plants result in dramatic changes in plant architecture.

167 earrangement of the mitochondrial genome and dramatic changes in plant growth.

168 esponse to low oxygen in HeLa cells leads to dramatic changes in plasma membrane structure.

169 accompanied by similarly fast and sometimes dramatic changes in population size and extensive gene f

170 n of endovascular techniques has resulted in dramatic changes in practice patterns and has refocused

171 to develop into oligodendrocytes and undergo dramatic changes in response to injury and demyelination

172 MPARs remains unchanged, suggesting that the dramatic changes in RI and the impairment in synaptic pl

173 We observed significant and dramatic changes in ringed seal stable isotope values be

174 vesicles in endocytic compartments leads to dramatic changes in scattering properties and SERS signa

175 in cellular tropoelastin protein levels and dramatic changes in secreted tropoelastin physical struc

176 Our results show that dramatic changes in selectivity can be obtained through

177 ubiquitin to a target protein, revealing the dramatic changes in shape that enable it to modify parti

178 Both zeatin and BR induce dramatic changes in signaling and metabolism.

179 We observed dramatic changes in single unit activity during learning

180 al muscle, which has the capacity to undergo dramatic changes in size and protein content, translatio

181 These trends may be associated with the dramatic changes in smoking behavior that took place in

182 Mast cell mediators induce dramatic changes in smooth muscle physiology, and the ex

183 the observed bidirectional scaling, whereas dramatic changes in spiking activity associated with spo

184 Here, we find that dramatic changes in spiking activity in the embryonic sp

185 lyldimethylammonium chloride) (PDADMAC) show dramatic changes in ST when the concentration of SDS var

186 Our results highlight dramatic changes in structure and function along the len

187 he GB and that these boundaries undergo less dramatic changes in structure upon irradiation.

188 difications in the crystal structure lead to dramatic changes in symmetry and selection rules of vibr

189 myotome width and height accompanied by some dramatic changes in the alpha-bungarotoxin-labeled ACh p

190 pped in the caves, they were confronted with dramatic changes in the availability and type of food so

191 yer behavior of ceramides, some causing more dramatic changes in the bilayer properties, whereas othe

192 carcinoma cell-line HCT116 p53(++), causing dramatic changes in the cell cycle without DNA damage.

193 Dramatic changes in the cellular microenvironment are al

194 ate millions of erythrocytes daily, involves dramatic changes in the chromatin structure and transcri

195 Mice deficient in clock exhibited dramatic changes in the circadian rhythm of renal sodium

196 and show that familial mutations can induce dramatic changes in the crucial processes thought to be

197 species-centric approach neglects the often dramatic changes in the ecology of organisms during thei

198 ixing, our work highlights the potential for dramatic changes in the effects of parasites on host pop

199 in most organic electronics devices and that dramatic changes in the electronic properties can be ind

200 The dramatic changes in the epidemiology of Clostridium diff

201 Dramatic changes in the epidemiology of Culicoides-borne

202 Our data indicate dramatic changes in the epigenome due to diet and demons

203 Nonetheless, dramatic changes in the experimental spectra are observe

204 he actin-remodelling protein cofilin induces dramatic changes in the F-actin network and consequent c

205 at valence fluctuations of YbAl3 can lead to dramatic changes in the Fermi surface topology in recipr

206 e show that valence fluctuations can lead to dramatic changes in the Fermi surface topology, even res

207 Moreover, the dramatic changes in the functional properties of PU02 in

208 E. chaffeensis infection did not result in dramatic changes in the global host SUMOylated protein p

209 alter the responses of NKT cells, leading to dramatic changes in the global immune response.

210 not ocean acidification, are already driving dramatic changes in the growth of an important reef-buil

211 on density at the heme iron, as evidenced by dramatic changes in the heme redox potential and pK(a) o

212 the wild-type level of activity, and showed dramatic changes in the light/dark cycle of CAM CO(2) fi

213 Exposure of KCs to PV sera also caused dramatic changes in the mitochondrial membrane potential

214 We found that E4orf4 induced dramatic changes in the morphology of mitochondria along

215 in molecular phylogeny are about to lead to dramatic changes in the naming of medically important mo

216 Dramatic changes in the North American landscape over th

217 Dramatic changes in the NRVS are seen under high-CO cond

218 Nonetheless, BMSC treatment produced dramatic changes in the number and activation of brain a

219 ommon and more intense forest fires, causing dramatic changes in the nutrient storage and loss from f

220 The attachment of functional groups leads to dramatic changes in the optoelectronic properties of the

221 the GTP-binding protein, ARF6, that provokes dramatic changes in the organization of epithelial cysts

222 of host innate immune responses may lead to dramatic changes in the outcome of infection.

223 Small-bowel radiology has undergone dramatic changes in the past 2 decades.

224 Adult pair bonding involves dramatic changes in the perception and valuation of anot

225 Energetic radiation can cause dramatic changes in the physical and chemical properties

226 es in the hP2X2 middle vestibule resulted in dramatic changes in the potency of zinc inhibition.

227 These studies implicate dramatic changes in the reaction mechanisms and suggest

228 tation (CLIP) sequencing, we uncover several dramatic changes in the RNA-binding properties of Gag th

229 article interactions are easily deduced from dramatic changes in the scattering profiles of interacti

230 ked strands (e.g., 5'3' vs 3'3') can lead to dramatic changes in the self-assembly behavior, from the

231 We discovered dramatic changes in the sequence variation and abundance

232 f interactions among neurons can manifest as dramatic changes in the state of population dynamics in

233 Dramatic changes in the stem cell ethical and research e

234 analysis revealed that an oprD mutant showed dramatic changes in the transcription of genes that may

235 ins and well below the doping level at which dramatic changes in the transport properties are reporte

236 AFS spectra of Zn model compounds, indicates dramatic changes in the Zn speciation from upstream to d

237 us arthropods and provides opportunities for dramatic changes in their abundance and richness.

238 d Leiocephalus carinatus was associated with dramatic changes in their foraging niche.

239 During development, cells undergo dramatic changes in their morphology.

240 r solution, the core-shell particles display dramatic changes in their morphology.

241 Alphaviruses, such as Sindbis virus, undergo dramatic changes in three-dimensional structure upon exp

242 The dramatic changes in TNTBN provide evidence that the tran

243 Our analysis reveals dramatic changes in total genomic order: Commitment of t

244 The dramatic changes in viral load and CD4 cell count after

245 essing the touristic impacts and address the dramatic changes in visitor population and drug consumpt

246 argely circadian driven as fish show similar dramatic changes in visual responsiveness when maintaine

247 Calcium stress induces dramatic changes in VSMC exosome composition and accumul

248 cosystems, hurricanes and flooding can cause dramatic changes in water quality resulting in large mor

249 lucan to a simple defined medium resulted in dramatic changes in X. fastidiosa's phenotype and gene-e

250 so been associated with similar, albeit less dramatic, changes in methylation patterns, leading to th

251 Thus, we demonstrate that the dramatic changes incurred by Dehnel's phenomenon occur i

252 The reason for this dramatic change is not apparent, but we propose that it

253 d that the Ae. tauschii region has undergone dramatic changes; it has acquired more than 80 non-synte

254 ication of the protein solution results in a dramatic change of binding preferences, with apo-Tf beco

255 different behavior, which we attributed to a dramatic change of the amyloid structure.

256 Loss of trol causes a dramatic change of the ECM into a three-dimensional, spo

257 These studies reveal a dramatic change of the HJ dynamics.

258 We found a dramatic change of the overall tertiary structure of pro

259 upon hybridization with hgDNA584 leads to a dramatic change of the pillar scale due to hgDNA584 fill

260 conclude that light exposure does not cause dramatic change of Trp104 from "Trp-in" to "Trp-out" con

261 phenomenon, the lattice may be coupled with dramatic changes of orbital and/or the spin-state of the

262 -type to an ordered-ilmenite structure, and dramatic changes of the electrical and magnetic properti

263 ferroelastic domain walls in SrTiO3 leads to dramatic changes of the magnetic domain structure of a n

264 h initiates photomorphogenesis, resulting in dramatic changes of the seedling's physiology.

265 The Earth's climate has experienced dramatic changes over the past 22,000 years; however, th

266 This quite dramatic change possibly occurs as a result of competiti

267 tment of acute ischemic stroke has undergone dramatic changes recently subsequent to the demonstrated

268 that strong electron-phonon coupling and its dramatic change should be incorporated into or reconcile

269 The field of hepatology has experienced dramatic changes since the last workforce study in hepat

270 ract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial co

271 sequence changes at promoters, we show that dramatic changes such as the complete gain and loss (col

272 One dramatic change that occurs is the closure of the ductus

273 punctuation: it consists of abrupt bursts of dramatic change that separate long periods of largely un

274 why we believe that we are on the cusp of a dramatic change that will sweep a wave of automation int

275 Polyploidization is one of the most dramatic changes that can occur in the genome.

276 lizations in infant marmoset monkeys undergo dramatic changes that cannot be solely attributed to sim

277 They were shaped by the dramatic changes that occurred in the evolution of the p

278 modern cosmopolitan lifestyle resulted in a dramatic change to the human gut microbiome.

279 erahertz microscopy, we find that there is a dramatic change to the vibrational directionality with i

280 nerozoic despite similar, and sometimes more dramatic changes to carbon sinks.

281 man cytomegalovirus (HCMV) infection induces dramatic changes to central carbon metabolism, including

282 G0 entry involves dramatic changes to chromatin and transcription of cells

283 The differentiation of gametes involves dramatic changes to chromatin, affecting transcription,

284 d the primate ancestor does not indicate any dramatic changes to exons or XIST-specific repeats; rath

285 ate within the genome and therefore engender dramatic changes to genome architecture.

286 We find that dramatic changes to the bulk solvent cause only weak cha

287 uence on development starts to decrease, and dramatic changes to the cell cycle take place.

288 Dramatic changes to the chromatin structure of Drosophil

289 Time delays may cause dramatic changes to the dynamics of interacting oscillat

290 immature and mature HAstV particles revealed dramatic changes to the exposure of conserved residues d

291 parasite, Plasmodium falciparum, results in dramatic changes to the host cell structure and morpholo

292 Our results demonstrate dramatic changes to transcription and chromatin structur

293 son whose number and activity do not undergo dramatic changes upon inbreeding or outcrossing.

294 ally silenced during retinogenesis, the most dramatic change was derepression of cell-type-specific d

295 Among the most dramatic changes, we observed rapid and sustained phosph

296 The most dramatic changes were caused by variants that produced A

297 y 3, Day 11 and Day 27 was evident, and more dramatic changes were found between baseline and other t

298 e funding in the United States is undergoing dramatic change which will require a new set of assumpti

299 HSCs undergo dramatic changes with aging.

300 here over the past two decades has witnessed dramatic changes, with continuous improvement in develop