ライフサイエンスコーパス: drebrin A

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します

1 ebrin A more strongly than spines containing drebrin A.

2 and areal density of spine profiles lacking drebrin A.

3 Drebrin A, an actin-binding protein, is a key regulatory

4 ment in the proportion of spines labeled for drebrin A and no significant change in spine density at

5 We sought to determine whether drebrin A arrives at the plasma membrane of neurons, in

6 overed two domains in the N-terminal half of drebrin-a coiled-coil domain and a helical domain-that i

7 d beyond for both genotypes, suggesting that drebrin A confers stability to postsynaptic spines.

8 nts confirmed that the reduced proportion of drebrin A-containing spines in brains of FAD mice at 6 m

9 Western blotting showed that drebrin A emerges at postnatal day (PNd) 6 and becomes p

10 x of 2xKI mice, in which synapse density and drebrin A immunoreactivity levels remain unchanged at 6

11 At PNd7, patches of drebrin A immunoreactivity were discretely localized to

12 highly significant reduction in the level of drebrin A immunoreactivity within each spine.

13 nths and older, a larger fraction of spinous drebrin A in 2xKI mice was located near the synaptic mem

14 this end, a new antibody was used to locate drebrin A in relation to electron microscopically imaged

15 , consistently supporting the involvement of drebrin A in spinogenesis and synaptogenesis.

16 ght microscopy showed high concentrations of drebrin A in the synaptic layers of the hippocampus and

17 Electron microscopy revealed that drebrin A in these regions is located exclusively in den

18 Drebrin A is a neuron-specific, actin binding protein.

19 Drebrin A is one protein reported to modulate spine size

20 esumably excitatory) synapses and containing drebrin A is reduced and if so, whether this occurs prio

21 proportion of hippocampal spines containing drebrin A is reduced and this change is accompanied by a

22 These findings indicate that drebrin A is required for the rapid (<30 minutes) form o

23 In adulthood, nearly all of the synaptic drebrin A is within spines forming asymmetric excitatory

24 Thus, drebrin A may be involved in organizing the dendritic po

25 thood depends on an F-actin binding protein, drebrin A, mice deleted of the adult isoform of drebrin

26 s, soluble Abeta could affect spines lacking drebrin A more strongly than spines containing drebrin A

27 creased levels of synaptophysin, PSD-95, and drebrin A protein levels.

28 Finally, we show that drebrin, a protein known to mediate interactions between

29 The drebrin A sites exhibited only thin postsynaptic densiti

30 al density of postsynaptic spines containing drebrin A was relatively constant from 3 to 18 months an

31 Thus, we examined levels of drebrin A within postsynaptic spines in the hippocampus

32 , the proportion of postsynaptic spines with drebrin A within somatosensory cortex layer I was smalle

WebLSDに未収録の専門用語（用法）は "新規対訳" から投稿できます。