ライフサイエンスコーパス: drug delivery

1 therapies, immunotherapy, radiotherapy, and drug delivery).

2 ssays, diagnosis, affinity purification, and drug delivery.

3 improved diagnostics, drug development, and drug delivery.

4 ease state since it dramatically hinders the drug delivery.

5 , separation, environmental remediation, and drug delivery.

6 icles for targeted and sustained intradermal drug delivery.

7 lease systems represents a major obstacle in drug delivery.

8 d/or increase cell membrane permeability for drug delivery.

9 toward strategies for improving nanoparticle drug delivery.

10 c microneedles offer an efficient method for drug delivery.

11 to be one of the most challenging aspects of drug delivery.

12 and potentially also for specific anticancer drug delivery.

13 precise temperature control for image-guided drug delivery.

14 modification steps to use CONs for targeted drug delivery.

15 d (NIR) light is developed for intracellular drug delivery.

16 limitations to their use for target specific drug delivery.

17 are widely used in catalysis, photonics, and drug delivery.

18 ave emerged as promising tools for localized drug delivery.

19 r metabolic engineering, nanotechnology, and drug delivery.

20 f the vagina, focussing on areas relevant to drug delivery.

21 arily designed for facilitating percutaneous drug delivery.

22 n the carrier and drug are commonly used for drug delivery.

23 n overview of polymeric gels in intravaginal drug delivery.

24 as safe and efficient carriers for targeted drug delivery.

25 ctly encapsulate medical agents for enhanced drug delivery.

26 tion from ores and nuclear waste, as well as drug delivery.

27 that have shown critical value in advancing drug delivery.

28 ith small particle sizes (20-30 nm) for dual drug delivery.

29 ented, with special attention to transdermal drug delivery.

30 separation, molecular sensing, catalysis and drug delivery.

31 y, to synthesis and optimization, to peptide drug delivery.

32 l structure, minimize metastasis, and aid in drug delivery.

33 fa (PEGPH20) degrades HA, thereby increasing drug delivery.

34 ising drug carrier platforms for intraocular drug delivery.

35 apsing blood and lymphatic vessels, limiting drug delivery.

36 netration and retention after pericardial NP drug delivery.

37 l properties that are suitable for effective drug delivery.

38 ll summarize and analyze the advances in the drug delivery across the BBB using various NPs in the la

39 ultrasound therapy is a promising method of drug delivery across the blood-brain barrier (BBB) for t

40 sing active transport alternative to passive drug delivery across the endothelial cell barrier.

41 opment of new drugs, or combination of novel drug delivery agents to evade P-gp-dependent efflux.

42 These results indicate that the intranasal drug delivery allows for the direct delivery of the PEI-

43 e data suggest considerable heterogeneity in drug delivery among patients and within DIPG tumors and

44 ive fashion and achieve enhanced transdermal drug delivery and "targeted" intradermal vaccine adminis

45 e potential to impact the fields of targeted drug delivery and active actuators.

46 points of view of drug conjugate synthesis, drug delivery and analytic detection.

47 interest as nontoxic substrates for targeted drug delivery and as highly biostable fluorescent marker

48 produce nanofilms that are better suited for drug delivery and biomedical applications by reducing th

49 ospheres-scaffold hybrid system (CM-ALs) for drug delivery and bone tissue engineering application.

50 ng application of CM-ALs (10%) scaffolds for drug delivery and bone tissue engineering.

51 otential applications in sensing, controlled drug delivery and communication between compartments in

52 pplications of avidin-based nanoparticles in drug delivery and diagnosis.

53 "blood-tumor barrier" (BTB), which inhibits drug delivery and distribution.

54 cations for the design of new interventions, drug delivery and dosing mechanisms, and public health p

55 iscovery, and its role in the improvement of drug delivery and efficacy.

56 rs are discussed, including gene regulation, drug delivery and materials design.

57 bable vascular scaffold (BVS) provides early drug delivery and mechanical support functions similar t

58 nstruction of biomaterials that are used for drug delivery and multimodal imaging, among others.

59 ch attention with respect to applications in drug delivery and nanomedicine as a result of their bioc

60 net movement opens new clinical concepts for drug delivery and new classifications and therapeutic op

61 linical implications, including concepts for drug delivery and new classifications and therapeutic op

62 lank slate' to evolve desired properties for drug delivery and other biomedical applications, while a

63 is work may promote better design of NPs for drug delivery and other nano-medical applications.

64 Successful drug delivery and overcoming drug resistance are the pri

65 acy of 1.2% RSV and 1.2% ATV gels as a local drug delivery and redelivery system adjunct to scaling a

66 ntitious materials, bone-tissue engineering, drug delivery and refractory materials, and use molecula

67 nism to stabilize proteins in the context of drug delivery and regenerative medicine.

68 Physiologic barriers to drug delivery and selection for drug resistance limit su

69 and NDs as a three-dimensional scaffold for drug delivery and stem cell-guided bone regeneration.

70 for real-time self-monitoring intracellular drug delivery and targeting multimodal imaging-guided sy

71 s) have undergone extensive investigation as drug delivery and targeting vehicles.

72 ostasis and pharmacology, including targeted drug delivery and the mediators of leukocyte trafficking

73 Here, we discuss how drug delivery and therapeutic efficacy are greatly hinde

74 onment toward immunostimulation and improves drug delivery and therapeutic outcomes.

75 rsed the negative effect of VEGF ablation on drug delivery and therapeutic response in anti-VEGF-resi

76 class of responsive polymers attractive for drug delivery and tissue engineering applications.

77 ant biomedical applications, specifically in drug delivery and tissue regeneration.

78 sposed miRNAs to become ideal candidates for drug delivery and tissue regeneration.

79 a vast number of applications from energy to drug delivery and to agriculture.

80 of drugs in nanocarriers provides effective drug delivery and toxicity reduction.

81 imize therapeutic nanocarriers for improving drug delivery and treatment for invasive brain tumors.

82 tion of viruses to be safe and effective for drug delivery and vaccine applications; the ability to d

83 However, drug delivery and vector distribution differences in tum

84 cal applications, including medical imaging, drug delivery, and antimicrobial coatings.

85 de a highly promising approach for localized drug delivery, and are an emerging field of interest in

86 that calcified plaque limited intravascular drug delivery, and controlled OAS treatment of calcific

87 al administration is of growing interest for drug delivery, and its utility is being increasingly inv

88 potential applications in materials science, drug delivery, and nanoelectronics.

89 ssing, optics, energy technology, dentistry, drug delivery, and personalized medicine.

90 luding chemical sensing, biological imaging, drug delivery, and photothermal therapy.

91 ications, including bariatric interventions, drug delivery, and tissue engineering.The use of drug de

92 is review examines the breadth of EVA use in drug delivery, and will aid the researcher in locating k

93 pharmaceutical agent encapsulation, targeted drug-delivery, and theranostics.

94 aracterization studies for ligand screening, drug delivery, antibody production and protein complex f

95 rapid development of microneedle devices for drug delivery applications into skin.

96 ly characterised and suitable to be used for drug delivery applications.

97 ve laboratory-scale productivity for further drug delivery applications.

98 in many water-based materials, sensing, and drug delivery applications.

99 gelators (LMWGs) are promising scaffolds for drug-delivery applications.

100 The rational design of drug delivery approaches leveraging supramolecular chemi

101 in cell imaging, organic dye adsorption, and drug delivery are examined.

102 In the drug delivery area, versatile therapeutic systems intend

103 todynamic priming (PDP) strategy can relieve drug delivery barriers in the tumor microenvironment to

104 applications in the field of gene delivery, drug delivery, bio-imaging, tissue engineering, and anti

105 growing interest owing to their potential in drug delivery, biocomputing, and diagnostic applications

106 ications, graphene is especially involved in drug delivery, biosensing and tissue engineering, with s

107 ymer micelles may not only be interesting in drug delivery but also for applications such as micellar

108 e a number of emerging areas in intravaginal drug delivery, but the vagina is a challenging route of

109 ng workplace aerosols and those produced for drug delivery by inhalation.

110 helium presents a major transport barrier to drug delivery by only allowing selective extravasation o

111 alent interactions, engineered approaches to drug delivery can be realized.

112 Intravaginal drug delivery can elicit a local effect, or deliver drug

113 and demonstrates low-voltage operation, high drug-delivery capacity, and high ON/OFF ratio.

114 s in areas such as biomimetic encapsulation, drug delivery, catalysis and biosensing.Functional nanos

115 s storage and separations, chemical sensing, drug delivery, catalysis, and nanoscale devices.

116 unctions such as gas adsorption, separation, drug delivery, catalysis, and sensing.

117 They find applications in catalysis, drug delivery, cleaning, etc.

118 , Au shell), each forming a light-responsive drug delivery complex.

119 ate pulmonary tumour models, nanotherapeutic drug delivery correlated with TAM heterogeneity, and suc

120 Nanoparticle (NP)-based pericardial drug delivery could provide a strategy to concentrate th

121 photo)sensors, photonics, photovoltaics, and drug delivery demonstrate the vast potential of the SBMs

122 Our study showed that a single drug delivery device loaded with a proprietary hypotensi

123 Therefore, a drug delivery device that can achieve drug release over

124 ic efficacy of polycaprolactone intracameral drug delivery devices in rabbit eyes.

125 egradable polymers have been demonstrated in drug delivery devices.

126 highly versatile, biocompatible polymer for drug delivery devices.

127 he ability of the controller to modulate the drug delivery dosage within a therapeutically effective

128 n potentially be manipulated to increase the drug delivery efficacy because of their effects on parti

129 vasculature during progression may influence drug delivery efficiency.

130 ch as in gas storage, catalysis, sensing and drug delivery, electrical semiconductivity and its contr

131 fications have resulted in new mechanisms of drug delivery enhancement and followed by the expansion

132 Microneedles is the technique of drug delivery enhancement, which was primarily designed

133 and microfluidic technology, diagnostics and drug delivery etc.

134 DS sentinel hospital-based and two CDC-based drug delivery facilities (DDFs) in Guangdong Province wa

135 The future of the drug delivery field depends on how effectively we can fi

136 The drug delivery field is at the strategic inflection point

137 In the drug delivery field, many breakthrough formulations have

138 will play a vital role in the future of the drug delivery field.

139 nanomaterials with applicability within the drug-delivery field.

140 The combination of hyperthermia-triggered drug delivery followed by ablation showed the best thera

141 corneum and therefore enhancement of topical drug delivery, for two decades the technique has progres

142 The benefits to intracellular drug delivery from nanomedicine have been limited by bio

143 FU) and microbubbles (MBs) can improve tumor drug delivery from non-thermosensitive liposomes (NTSLs)

144 as thermal ablation, hyperthermia-triggered drug delivery from temperature-sensitive liposomes (TSLs

145 Targeted drug delivery has become extremely important in enhancin

146 The application of nanoparticles (NPs) to drug delivery has led to the development of novel nanoth

147 However, clinical use of NP-mediated drug delivery has not always translated into improved su

148 erability to Pavlovian drug cues paired with drug delivery, here, we demonstrate that their counterpa

149 se micelles as effective carriers for ocular drug delivery highlighting their performance in preclini

150 Gastric resident systems for drug delivery, ideally need to be: ingestible, be able t

151 of nanodiamond as a biomedical platform for drug-delivery, imaging, and subcellular tracking applica

152 ffer among human pathologies, limitations to drug delivery imposed by the unique characteristics of d

153 adherens junction and opens a new avenue for drug delivery in a broad range of biomedical research an

154 many promising applications for controllable drug delivery in biological systems.

155 hange tissue local permeability for enhanced drug delivery in both mouse tumors and mouse muscle.

156 Drug delivery in brain tumors is challenging because of

157 tor (CSF-1R) blockade and nanoparticle-based drug delivery in murine pulmonary carcinoma.

158 lerosis is a major challenge to intraluminal drug delivery in peripheral artery disease (PAD).

159 Ex vivo trans-sclera drug delivery in porcine eyes is demonstrated by utilizi

160 Ultrasound-mediated drug delivery in the gastrointestinal (GI) tract is a bo

161 st complexes - afford logical application to drug delivery in using drug as guest.

162 opene may be a promising application in oral drug delivery in various indications.

163 ogical inhibition of lysyl oxidases improved drug delivery in various tumor models and reversed the n

164 Real-time monitoring of tumor drug delivery in vivo is a daunting challenge due to the

165 mes are effective intracellular carriers for drug delivery into neutrophils.

166 Additionally, nanoparticles (NPs)-mediated drug delivery is emerging as an effective and non-invasi

167 Remotely controlled, localized drug delivery is highly desirable for potentially minimi

168 This study charts the growth of the drug delivery literature published during 1974-2015 from

169 rs usable in biomedical applications such as drug delivery, macroscopic injectables, tissue-engineeri

170 ny fields, including catalysis, imaging, and drug delivery, mainly due to the versatility of surface

171 To date, there is no periadventitial drug delivery method available in the clinic to prevent

172 is approach provides a physically controlled drug delivery method harnessing the biology of endotheli

173 diagnostics using in vivo liquid biopsy, and drug delivery methods.

174 Thus, in addition to percutaneous drug delivery, microneedles have been considered as an e

175 yers (SEAL), and create injectable pulsatile drug-delivery microparticles, pH sensors, and 3D microfl

176 and paratope-independent handles in targeted drug delivery, molecular imaging, and therapeutic drug m

177 Ds) have attracted considerable attention as drug delivery nanocarriers due to their low cytotoxicity

178 widely explored biodegradable polymer-based drug delivery NP.

179 , the folding step more directly relevant to drug delivery, occurs at more acidic pH values than prev

180 also established as a next step CL-activated drug delivery of DOX azide by showing significantly decr

181 Local drug delivery of Doxorubicin (Dox) with thermosensitive

182 h respect to understanding and improving the drug delivery of macromolecules to the central nervous s

183 Studies of bioimprint-based drug delivery on cancer cells have been recently trialle

184 rmacokinetics (including feedback-controlled drug delivery), opening new dimensions in personalized m

185 hrough the application of nanoparticle-based drug delivery, opening several exciting avenues for sele

186 cyclic peptide that can be used for targeted drug delivery or for enumerating circulating breast tumo

187 lications such as tissue scaffold templates, drug delivery, packaging, etc., due to their inherent su

188 The growth of publications on drug delivery paralleled the total scientific publicatio

189 und contrast agents in molecular imaging and drug delivery, particularly for cancer applications.

190 A drug delivery platform is comprised of NPs coated with a

191 he Biocage, a customizable implantable local drug delivery platform.

192 es have emerged as one of the most promising drug delivery platforms for the management of ocular dis

193 rative medicine applications including novel drug delivery platforms that facilitate the localized an

194 Effective intraocular drug delivery poses a major challenge due to the presenc

195 The success of receptor-mediated drug delivery primarily depends on the ability to optimi

196 r, has been slowing down, and many important drug delivery problems have not been resolved.

197 along with their utility for time-controlled drug delivery, protein delivery, cell encapsulation, and

198 d protein shells with improved stability for drug delivery purposes.

199 drug nanocarriers of potential interest for drug delivery purposes.

200 On-target drug delivery remains a challenge in cancer precision me

201 maceutics) published nearly one-fifth of the drug delivery research in 2014-2015.

202 g the last 15years, the journals targeted by drug delivery research increased nearly 2.4 fold (416 to

203 als (Journal of Controlled Release, Advanced Drug Delivery Reviews, and International Journal of Phar

204 en and LLL12 loaded SRMs provide a promising drug delivery strategy for more effective treatment of h

205 The CL-targeted drug delivery strategy may potentially be used for dual-

206 nd a 2D endothelium model for cross-talk and drug delivery studies.

207 The present study reports a drug delivery system comprising nanostructured lipid car

208 This novel drug delivery system is comprised of a thermoresponsive

209 tly, MCTS have also been widely exploited in drug delivery system research for comprehensive study of

210 ated to their applications in tumor-targeted drug delivery system research.

211 in, we report on an effective brain-targeted drug delivery system that combines a robust red blood ce

212 this manuscript, we present a novel micellar drug delivery system that is not only capable of releasi

213 her development of a sustainable intraocular drug delivery system to protect RGCs, which may be appli

214 e aim to develop an RGC-targeted intraocular drug delivery system using unimolecular micelle nanopart

215 y higher in mice receiving the targeted nano-drug delivery system when compared to non-targeted syste

216 onstrate that [S]-PM is a promising targeted drug delivery system, which can be advanced for the trea

217 general, emphasized and investigated in each drug delivery system.

218 le physicochemical properties for a targeted drug delivery system.

219 The implantable drug-delivery system can be powered with a TENG device r

220 erator (TENG)-based self-powered implantable drug-delivery system is presented.

221 DK inhibitor conjugates with folic acid as a drug-delivery system targeting folate receptors.

222 A "relay drug delivery" system based on two distinct modules, whi

223 Among drug delivery systems (DDSs), smart nanocarriers that re

224 mprehensively describes various NPs-mediated drug delivery systems according to different NPs species

225 context, we review recent development of PTX drug delivery systems and analyze the design principles

226 ation and accumulation of nanoparticle-based drug delivery systems are highly dependent on the partic

227 New drug delivery systems are highly needed in research and

228 Tumor-targeted drug delivery systems are promising for their advantages

229 ring the pH differences in the body, various drug delivery systems can be designed by utilizing smart

230 ortant immune functions, and accumulation of drug delivery systems could have significant implication

231 Systemically injected drug delivery systems distribute into various organs and

232 g this non-covalent interaction in nanoscale drug delivery systems for pharmaceutical agents, includi

233 delivery, and tissue engineering.The use of drug delivery systems for the gastrointestinal tract has

234 potential for use of polymers in controlled drug delivery systems has been long recognized.

235 strategy for engineering stimuli-responsive drug delivery systems in a bioinspired and synergistic f

236 Nanoparticles are emerging as targeted drug delivery systems in chronic inflammatory disorders.

237 roach can be used to monitor accumulation of drug delivery systems in preclinical and clinical studie

238 crucial parameter for their potential use as drug delivery systems in vivo.

239 In particular, nanoparticle-based drug delivery systems not only facilitate the delivery o

240 as been utilized in developing polymer-based drug delivery systems over the past 10years.

241 Nanoparticle-based drug delivery systems provide a highly promising approac

242 the importance in translating liposome-based drug delivery systems to other molecules and cargo.

243 iomedical applications ranging from advanced drug delivery systems to tissue engineering.

244 Targeted drug delivery systems using nanoparticle nanocarriers of

245 d delivery of bioactive moieties, anticancer drug delivery systems, and theranostics (i.e., real-time

246 ne in cancer is the development of effective drug delivery systems, primarily nanoparticles.

247 logies, including actuators, motion sensors, drug delivery systems, projection displays, etc.

248 e design of the next-generation of nanoscale drug delivery systems.

249 echnology, nanomedicine, and many nano-sized drug delivery systems.

250 problem, researchers are investigating novel drug delivery systems.

251 ducts, ranging from processed foods to novel drug delivery systems.

252 ing cellular uptake and nuclear targeting of drug delivery systems.

253 g MDR and recent progress of combined NO and drug delivery systems.

254 possible applications in drug synthesis and drug delivery systems.

255 l research and development led to commercial drug delivery systems.

256 ssible when combined with molecular-targeted drug delivery systems.

257 properties of these novel nanoconstructs as drug-delivery systems highlight the potential of this ap

258 biomaterial in many applications, including drug-delivery systems, bone-graft fillers and medical de

259 orward toward the development of implantable drug-delivery systems.

260 iomolecules is crucial for improving current drug-delivery systems.

261 with functional groups to accommodate modern drug delivery technologies, some of these compounds exhi

262 Liposomes are nanoparticles used in drug delivery that distribute over several days in human

263 We also discuss specific obstacles to drug delivery that make solid tumors difficult to treat,

264 to CONs for potential advantageous targeted drug delivery, this process can have a significant impac

265 To highlight the benefits of ADC dual drug delivery, this strategy was applied to the preparat

266 made toward the use of NDs in the fields of drug delivery, tissue engineering, and bioimaging.

267 eater drug permeability and improved adjunct drug delivery to diseased arteries.

268 l in utilizing the RPE cells as mediators of drug delivery to intracellular targets and surrounding t

269 s frequent injections and does not guarantee drug delivery to intracellular targets.

270 -tumor barrier (BTB) is a major obstacle for drug delivery to malignant brain tumors such as glioblas

271 noparticles have the capacity to concentrate drug delivery to phagocytic cells, significantly reducin

272 pected to have a myriad of applications from drug delivery to screening catalysts.

273 oxygen levels) for localized and controlled drug delivery to simultaneously kill bacteria and disman

274 potential application in fields ranging from drug delivery to synthetic biology.

275 ation, an alternative route for non-invasive drug delivery to the brain, bypasses the blood-brain-bar

276 However, optimized nanoparticle design for drug delivery to the central nervous system is limited b

277 Development of strategies to improve drug delivery to the CNS is now the primary focus in lys

278 ical targets to modulate neuroprotection and drug delivery to the CNS.

279 with examples in the literature of targeted drug delivery to the majority of organs within the human

280 ad can be useful as a molecular vehicle for drug delivery to the neuronal cytoplasm.

281 Currently, drug delivery to the posterior eye segment relies on int

282 not only a useful strategy for intracellular drug delivery to the RPE targets but might also be usefu

283 s may provide a microenvironment that limits drug delivery to the target cell and therefore renders t

284 mal necrosis in the tumor core and efficient drug delivery to the tumor rim.

285 erapeutic micromotors application for active drug delivery to treat gastric bacterial infection in a

286 method for potential application in targeted drug delivery to tumor cells with overexpressed nuclear

287 ugh biological gels is crucial for effective drug delivery using nanoparticles.

288 lopment of artificial sensors, receptors and drug-delivery vectors.

289 been part-modified with a polyoxazoline as a drug delivery vehicle for improving the therapeutic inde

290 articles (HNPs) have shown huge potential as drug delivery vehicles for pancreatic cancer.

291 imprints also have applications as selective drug delivery vehicles to tumours with the potential to

292 drug discovery, continuous manufacturing of drug delivery vehicles, and ultra-precise dosing of high

293 l structures with high potential as advanced drug delivery vehicles, bioreactors and artificial cells

294 sought to design a family of HP-beta-CD pro-drug delivery vehicles, known as polyrotaxanes (PR), cap

295 ied the synthesis of antibody-functionalized drug delivery vehicles, which were benchmarked against a

296 CL-activated drug delivery was also evaluated using the same azide ch

297 nstrated its superior capability in targeted drug delivery, which is not only useful for ovarian canc

298 antum dots with their recent applications in drug delivery will also be introduced.

299 d that the technique of microneedle-assisted drug delivery will soon become relevant for majority of

300 the utility of this approach to theranostic drug delivery with the potential of light-triggered rele