ライフサイエンスコーパス: drug dependence

1 bolism in regions associated with reward and drug dependence.

2 itical role in aversion, negative-reward and drug dependence.

3 and are being investigated as treatments for drug dependence.

4 ess while 34% met the DSM-III-R criteria for drug dependence.

5 eing seen with bulimia and alcohol and other drug dependence.

6 ting to impulsive and compulsive features of drug dependence.

7 le of antidepressant medications in treating drug dependence.

8 ferences in risk for relapse associated with drug dependence.

9 ntributes to the transition from drug use to drug dependence.

10 rain abnormalities associated with stimulant drug dependence.

11 isocial behavior, and alcohol, nicotine, and drug dependence.

12 groups for genetic investigations of illicit drug dependence.

13 including extension of liability to illicit drug dependence.

14 edisposed individuals for the development of drug dependence.

15 disorders, including Parkinson's disease and drug dependence.

16 iability likely extends to nonopioid illicit drug dependence.

17 how genetic risk mediates the development of drug dependence.

18 f the central nervous system (CNS) including drug dependence.

19 y to several major psychiatric illnesses and drug dependence.

20 ion, a well-characterised model for onset of drug dependence.

21 sis for restricted behavioral repertoires in drug dependence.

22 ignals to reinforcement learning accounts of drug dependence.

23 cificity for the transmission of alcohol and drug dependence.

24 in neuropsychiatric disorders, obesity, and drug dependence.

25 therapeutic interventions aimed at treating drug dependence.

26 cue-induced cocaine craving associated with drug dependence.

27 or conduct disorder, alcohol dependence, and drug dependence.

28 peralgesia (increased pain sensitivity), and drug dependence.

29 to contribute to schizophrenic psychosis and drug dependence.

30 4% and 7.7%, respectively) exceeded rates of drug dependence (0.6% and 2.6%, respectively).

31 most common axis I disorders were alcohol or drug dependence (15 subjects), depression (11 subjects),

32 may modify the susceptibility to alcohol or drug dependence (AD or ND).

33 ith a 2- to 3-fold excess risk of developing drug dependence (adjusted relative risk = 2.6, 95% confi

34 stance use disorder, alcohol dependence, and drug dependence after stratifying probands by the presen

35 assified as having a nonalcohol, nonnicotine drug dependence alone.

36 2 newly incident clinical features of DSM-IV drug dependence), among subjects with no prior clinical

37 traumatic stress disorder (PTSD) with DSM-IV drug dependence and abuse are from cross-sectional studi

38 We further review models of drug dependence and addiction and describe behavioral al

39 ewed with the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA).

40 d through the Semi-Structured Assessment for Drug Dependence and Alcoholism interview.

41 rol using the Semi-Structured Assessment for Drug Dependence and Alcoholism.

42 leus accumbens, which has been implicated in drug dependence and craving.

43 uring adolescence increases vulnerability to drug dependence and decreases the likelihood that indivi

44 The familial aggregation of drug dependence and habitual smoking in siblings of alco

45 or understanding individual vulnerability to drug dependence and novel treatments for the disorder.

46 oyed or underemployed have elevated rates of drug dependence and psychiatric comorbidities; consequen

47 t represents a candidate cognitive marker of drug dependence and treatment outcomes.

48 Chronic opioid-induced drug dependence and withdrawal syndrome after opioid ces

49 area known to be involved in development of drug dependence and withdrawal.

50 rain stress systems that are dysregulated in drug dependence and withdrawal.

51 itical in developing interventions to combat drug dependence and withdrawal.

52 disorders, substance dependence (alcohol and drug dependence), and suicide attempts.

53 Making maladaptive choices is a component of drug dependence, and concurrent reinforcement schedules

54 mediates anxiety associated with stress and drug dependence, and it regulates ethanol intake.

55 les, smoking status, alcohol use, alcohol or drug dependence, and major depression.

56 or Asian race, geographic region, alcohol or drug dependence, and recent hospitalization with mental

57 mbers--and therefore likely to have predated drug dependence--and which aspects are specific to drug-

58 ependence; (2) DSM-IV drug abuse; (3) DSM-IV drug dependence; and (4) emerging dependence problems (1

59 regation of antisocial personality disorder, drug dependence, anxiety disorders, and mood disorders s

60 The three independent mutations conferring drug dependence are M1103T, T1208A, and V1210A.

61 erlying synaptic plasticity in this model of drug dependence are therefore fundamentally similar to t

62 rug dependence, the other primarily to licit drug dependence-are needed.

63 This review selects drug dependence as a paradigmatic addiction, and further

64 on for 861 young adults (61% female) with no drug dependence at YAT0, low job control alone was assoc

65 clear evidence against the null hypothesis, drug dependence (beta = -0.27, P = 0.58) and long-term i

66 ive impairment, psychosis, recent alcohol or drug dependence, bipolar or severe personality disorder,

67 Both alcohol dependence and drug dependence bred true in families without evidence f

68 Among persons with alcohol and other drug dependence, CCM compared with a primary care appoin

69 provide compelling evidence that alcohol and drug dependence, childhood conduct disorder, adult antis

70 bilized outpatients meeting DSM criteria for drug dependence (cocaine, heroin, or cannabis) and serio

71 uits involved in motivation that can lead to drug dependence, craving and relapse.

72 tionships between variation in CHRM2 and AD, drug dependence (DD) and affective disorders, using a no

73 Drug dependence (DD) is commonly co-morbid with alcohol

74 ying transitions from first drug use (DU) to drug dependence (DD) onset, we estimate a parsimonious s

75 e dependence [alcohol dependence (AD) and/or drug dependence (DD)] and 338 EA healthy controls.

76 for the Genetics and Treatment of Antisocial Drug Dependence, Denver and Boulder.

77 ic application in the management of obesity, drug dependence, depression, and other disorders.

78 larger number of substances and having more drug dependence diagnoses and symptoms.

79 Care for patients with alcohol or drug dependence diagnoses was more restricted than was c

80 orbidity (panic disorder, social phobia, and drug dependence), disability and restricted activity day

81 ed with HIV may also have psychiatric and/or drug dependence disorders.

82 ana, and more than 12% screened positive for drug dependence during the previous 12 months.

83 Drug dependence generally has been treated as if it were

84 ated for alcoholism and/or other nonnicotine drug dependence had an increased cumulative mortality th

85 Studies of remission from drug dependence have most often been based on treatment

86 and treat HIV, tuberculosis, hepatitis, and drug dependence have proven successful in prisons and ar

87 r of HIV-related symptoms, illicit drug use, drug dependence, heavy alcohol use, and being unemployed

88 A recent genome-wide study of drug dependence identified an association between cocain

89 predicted drug dependence in relatives, and drug dependence in comparison probands increased the ris

90 Drug dependence in probands increased the risk for drug

91 ependence in probands increased the risk for drug dependence in relatives irrespective of ADHD status

92 In addition, ADHD in the proband predicted drug dependence in relatives, and drug dependence in com

93 ction and personality traits associated with drug dependence in stimulant-dependent individuals (N=50

94 nimal data are available on the treatment of drug dependence in this patient population.

95 ently associated with screening positive for drug dependence included having many HIV-related symptom

96 Craving is a hallmark of drug dependence, including dependence on nicotine.

97 Although drug dependence is common in patients with bipolar disor

98 uggest that the association between ADHD and drug dependence is most consistent with the hypothesis o

99 as helped shape the generally held view that drug dependence is primarily a social problem, not a hea

100 al predisposition in the human population to drug dependence is unknown.

101 delayed drug addition suggested (i) that the drug dependence lesion is at the stage of virus assembly

102 d late in growth cycles, suggesting that the drug-dependence lesion was at the step of virus assembly

103 Drug dependence may be at its core a pathology of choice

104 eir biological siblings without a history of drug dependence (N=50), and unrelated healthy volunteers

105 ndence (N=115 versus N=166, respectively) or drug dependence (N=78 versus N=203).

106 iral dynamics is modified to account for the drug dependence of intracellular delay and continuously

107 ty and amplified relaxation systolic load or drug dependence of ME-based indexes in failing versus co

108 , current clinical treatment for alcohol and drug dependence often excludes new pharmacotherapies app

109 The effects of drug dependence on social systems has helped shape the g

110 antisocial behavior, alcohol dependence, and drug dependence) on childhood disruptive disorders (atte

111 role in the transition to and maintenance of drug dependence once initiated.

112 n, diabetes mellitus, obesity, dyslipidemia, drug dependence or tobacco use, and renal disease.

113 Drug dependence produces significant and lasting changes

114 e in addiction while extending the idea that drug dependence represents a shift from initially recrea

115 Drug dependence should be insured, treated, and evaluate

116 nger age, being separated or divorced, other drug dependence, substance-induced psychiatric disorders

117 ibution), expand the traditional concepts of drug dependence that emphasize limbic-regulated response

118 factors-one predisposing largely to illicit drug dependence, the other primarily to licit drug depen

119 ght to play a key role in the maintenance of drug dependence through negative reinforcement.

120 nse to treatments (adherence and relapse) of drug dependence vs type 2 diabetes mellitus, hypertensio

121 ons, neither parental alcohol dependence nor drug dependence was associated with a higher risk for be

122 Evidence for the heritability of alcohol and drug dependence was found.

123 sent in 20% of participants, mainly men, and drug dependence was present in 13%.

124 eas the association between dependent PD and drug dependence was significantly greater (P <.04) among

125 ng positive for any psychiatric disorder and drug dependence were examined in multivariate logistic r

126 neuropeptide Y, nociceptin [orphanin FQ]) in drug dependence, with emphasis on the neuropharmacologic

127 roduct (multiple PDZ domain protein) affects drug dependence, withdrawal and relapse.

128 involved in addiction that may contribute to drug dependence, withdrawal and related processes.

129 e, Z=5.36, p<0.001; 3.4% vs. 1.1% males with drug dependence, Z=3.70; p<0.001).