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1 roaches can greatly speed up the traditional drug discovery process.
2 iology of psychiatric illness and aid in the drug discovery process.
3 physiologically relevant human cells in the drug discovery process.
4 nt but overlapping levels of openness in the drug discovery process.
5 st lead series during the early stage of the drug discovery process.
6 y polypharmacological compounds early in the drug discovery process.
7 rged as an especially important facet of the drug discovery process.
8 k for candidate drugs, thus facilitating the drug discovery process.
9 nd and higher cost-to-return benefits in the drug discovery process.
10 ased single cell analysis can bring into the drug discovery process.
11 xpression profiling across all phases of the drug discovery process.
12 ing is being routinely incorporated into the drug discovery process.
13 entify substrates, and this can speed up the drug discovery process.
14 core and the experimental data to impact the drug discovery process.
15 put screening of reactive metabolites in the drug discovery process.
16 cceptable attrition rates in the preclinical drug discovery process.
17 atalyzed reactions could thus facilitate the drug discovery process.
18 a new tool facilitating the structure-based drug discovery process.
19 and are typically the limiting factor in the drug discovery process.
20 as novel imaging platforms to facilitate the drug discovery process.
21 ield and their potential use in the oncology drug discovery process.
22 otential targets is an important step in the drug discovery process.
23 nated from consideration much earlier in the drug discovery process.
24 ols in combating late-stage attrition in the drug discovery process.
25 o purification that can be used to guide the drug discovery process.
26 ntinues to be one of the main drivers in the drug discovery process.
27 complexes is a critical step in the rational drug discovery process.
28 s for hERG channel activity early during the drug discovery process.
29 nerating components of the ADME profile in a drug discovery process.
30 onstrating the plugin's utility in the early drug discovery process.
31 , new strategies are required to advance the drug discovery process.
32 nction with mass spectrometry throughout the drug discovery process.
33 ime for providing metabolism feedback to the drug discovery process.
34 e potential to become a valuable tool in the drug discovery process.
35 rapies and is also a constituent part of the drug discovery process.
36 h to the biology of this organism and to the drug discovery process.
37 e usefulness of the SAR by NMR method in the drug discovery process.
38 lexes will be an important component of this drug discovery process.
39 ch for novel leads is a critical step in the drug discovery process.
40 l relevance to the successful outcome of the drug discovery process.
41 ease and acting as a pivotal enabler for the drug-discovery process.
42 s will prove to be valuable additions to the drug-discovery process.
44 t may become important lead compounds in the drug discovery process aimed at developing new treatment
46 a for the application of metabolomics in the drug discovery process and in personalized medicine.
47 y had a positive impact on all stages of the drug discovery process and, increasingly, on the drug de
48 and validation remain difficult steps in the drug discovery process, and uncovering the core genes an
49 ity-oriented synthesis and their role in the drug discovery process are presented in this review.
52 human physiology, are starting to impact the drug discovery process, but their implementation has bee
53 binatorial chemistry has deeply impacted the drug discovery process by accelerating the synthesis and
54 In short, microarrays are redefining the drug discovery process by providing greater knowledge at
55 logical imaging into the early stages of the drug discovery process can provide invaluable informatio
57 natural products in order to accelerate the drug discovery process for high-throughput screening in
58 ed to other MBLs and in this way improve the drug discovery process for this important class of drug
60 gh-throughput screening (HTS) systems in the drug discovery process has resulted in an increasing nee
61 ations about significant improvements in the drug discovery process, healthcare and economic developm
62 eutic compounds is starting to influence the drug discovery process; however, the use of these cells
63 d excretion) models may be used early in the drug discovery process in order to flag drug candidates
64 e of disease-relevant human biology into the drug discovery process, informing target and compound va
71 f metabolomics as a routine component of the drug discovery process may provide some solutions to the
72 Incorporating these findings in the cancer drug discovery process might lead to better therapeutics
73 l integration of these technologies into the drug discovery process provides the promise of increased
74 s have been applied at several stages of the drug discovery process, ranging from target identificati
76 ening for enzyme discovery, engineering, and drug discovery processes require simple, fast, and sensi
77 permeation assay (PAMPA), widely used in the drug discovery process to estimate permeability in vivo.
78 d development of nintedanib from the initial drug discovery process to the latest available clinical
80 y unique scaffolds from myxobacteria for the drug discovery process, we used LC-SPE-NMR-MS techniques
81 he early hit- and lead-finding phases of the drug discovery process when larger numbers of compounds
82 e implemented at a much earlier stage of the drug discovery process, when molecular property changes
84 role of molecular imaging in the therapeutic drug discovery process will also be reviewed, as this is
85 d toxicity of drug candidates earlier in the drug discovery process will speed up the introduction of
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