ライフサイエンスコーパス: drug-associated

1 high titers of anti-MPO antibodies are often drug-associated.

2 DNA variants appearing to predispose to drug-associated "acquired" long-QT syndrome (aLQTS) have

3 Because of historically high rates of drug-associated adverse events, warfarin remains underpr

4 d thrombocytopenia (6%) were the most common drug-associated adverse events.

5 interrupted in 9 patients (1.5%) because of drug-associated adverse events.

6 asculitis may quickly develop a superimposed drug-associated ANCA-positive vasculitis.

7 ions, such as nonsteroidal anti-inflammatory drug-associated angioedema and serum sickness-like react

8 Drug-associated B-cell activation may contribute to this

9 cocaine and encodes information that drives drug-associated behaviors.

10 An increase in preference for the drug-associated compartment is observed after a single e

11 drug-seeking behavior that was maintained by drug-associated conditioned reinforcers and assessed usi

12 ions in cocaine seeking under the control of drug-associated conditioned reinforcers.

13 mote cocaine-seeking behavior in response to drug-associated conditioned stimuli (CS) and share dense

14 On the test day, rats exposed to the drug-associated context, after extinction in a different

15 a significant increase in preference for the drug-associated context, with a linear trend for increas

16 re-activation of these neuronal ensembles by drug-associated contexts during abstinence provoked drug

17 sociation between drug rewarding effects and drug-associated contexts has remained unclear.

18 s examining the potential reconsolidation of drug-associated contextual memories, rats were given a s

19 a renewal procedure, the authors report that drug-associated contextual stimuli play a critical role

20 derlying relapse to drug seeking elicited by drug-associated contextual stimuli.

21 iii) a test that offers a choice between the drug-associated cue and a neutral cue.

22 dependent increase in their response for the drug-associated cue as compared to mice that self-admini

23 (CPP) or less time (CPA) in proximity to the drug-associated cue.

24 VTA dopamine neurons blocked the ability of drug-associated cues (but not a cocaine prime) to reinst

25 mental drug-seeking behavior that depends on drug-associated cues acting as conditioned reinforcers.

26 ratio schedule and reinstatement induced by drug-associated cues and stress.

27 tablished as associations are formed between drug-associated cues and the conditioned responses they

28 However, drug-associated cues are also known to provoke striatal

29 Drug-associated cues are believed to be important mediat

30 Drug-associated cues can acquire powerful motivational c

31 ning addictive behaviors, as presentation of drug-associated cues can elicit drug seeking and relapse

32 g abuse; however, it remains unclear whether drug-associated cues can elicit the emotional withdrawal

33 Here, Wheeler and colleagues show that drug-associated cues come to activate neural representat

34 Drug-associated cues elicit conditioned responses in hum

35 Drug-associated cues have profound effects on an addict'

36 ed that the PL-NAcC pathway was recruited by drug-associated cues in a dopamine-dependent manner to d

37 uggest that LTCC blockade during exposure to drug-associated cues may cause unlearning of the increas

38 ty to addiction involves robust memories for drug-associated cues that are difficult to extinguish.

39 and relapse can be triggered by exposure to drug-associated cues that induce drug craving.

40 prefrontal cortex that are thought to allow drug-associated cues to drive compulsive drug seeking an

41 t aspect of drug addiction is the ability of drug-associated cues to elicit craving and facilitate re

42 method to reduce the motivational impact of drug-associated cues to prevent relapse.

43 powerful and sometimes surprising ways, and drug-associated cues trigger relapse to drug seeking in

44 ute to the increased motivational valence of drug-associated cues triggering relapse.

45 evealing a bottleneck in brain processing of drug-associated cues where therapeutic interventions cou

46 t glutamatergic responses to drugs of abuse, drug-associated cues, and stressors.

47 g seeking becomes habitual and controlled by drug-associated cues, and the neural locus of control ov

48 oms including enhanced incentive salience of drug-associated cues, but also a negative affective stat

49 hat in the absence of conscious awareness of drug-associated cues, cocaine and alcohol activate only

50 Drug use is provoked by the presentation of drug-associated cues, even following long periods of abs

51 is frequently triggered by an encounter with drug-associated cues, including the drug itself.

52 cute exposure to the self-administered drug, drug-associated cues, or stress.

53 to drug seeking can be caused by exposure to drug-associated cues, provoking drug craving even after

54 ase where relapse is elicited by exposure to drug-associated cues, the drug itself, or stress.

55 aviour that depends upon the presentation of drug-associated cues, without having any intrinsic, prim

56 cessive attribution of incentive salience to drug-associated cues.

57 ute to the attribution of incentive value to drug-associated cues.

58 Relapse to drug use can be initiated by drug-associated cues.

59 cue-induced reinstatement in the absence of drug-associated cues.

60 ceptibility, and relapse can be triggered by drug-associated cues.

61 that are selectively activated by drugs and drug-associated cues.

62 l immune-related adverse events and consider drug-associated dermatomyositis in the differential diag

63 In rodents, exposure to a drug-associated environment elicits conditioned psychomo

64 he prior history of morphine exposure in the drug-associated environment, since alterations of AMPAR

65 ulnerability to relapse that are elicited by drug-associated environmental stimuli.

66 nisms that mediate the effects of real-world drug-associated environments on drug taking behavior und

67 with high titers of anti-MPO antibodies are drug-associated, especially following exposure to hydral

68 Recognition of a drug-associated etiology in a patient with TTP-HUS is cr

69 ecision making may also strongly depend upon drug-associated expectations.

70 rse interaction drugs, drug primary targets, drug-associated genes, and proteins directly interacting

71 In this overview, we discuss specific drug-associated hemostatic complications, the already kn

72 of malate dehydrogenase displayed prominent drug-associated increases in expression compared with un

73 ory processes and may play critical roles in drug-associated learning and addiction.

74 at disrupting ASIC1A in the NAc would reduce drug-associated learning and memory.

75 f torsades de pointes (TdP) in patients with drug-associated long QT syndrome (LQTS).

76 was a case-control study of 123 adults with drug-associated LQTS.

77 circuitry, which underlies the formation of drug-associated memories and addictive behavior.

78 Drug-associated memories are susceptible to long-term di

79 anol experience may promote the formation of drug-associated memories by enhancing synaptic plasticit

80 nomenon that correlates with the strength of drug-associated memories in vivo.

81 Retrieval of drug-associated memories is critical for maintaining add

82 enetic mechanism, nucleosome remodelling, in drug-associated memories remains largely unexplored.

83 Thus, drug-associated memories seem to be actively maintained

84 g to the formation and persistence of strong drug-associated memories that lead to craving and relaps

85 ddiction, and the dopamine signal influences drug-associated memories that perpetuate drug use.

86 evention therapies attempt to interfere with drug-associated memories, but are often hindered by unin

87 ucleus accumbens (NAc) is essential to these drug-associated memories, but underlying mechanisms are

88 ic potentiation, thus, likely contributed to drug-associated memories.

89 re also necessary for the reconsolidation of drug-associated memories.

90 a memory reactivation session disrupted the drug-associated memory and abolished subsequent instrume

91 neural circuitry that mediates expression of drug-associated memory is therefore of crucial importanc

92 evidence implicates epigenetic mechanisms in drug-associated memory processes.

93 blockade could induce long-term deficits in drug-associated memory retrieval by reducing neuronal ex

94 y of dorsal hippocampus (dHipp) beta-ARs for drug-associated memory retrieval.

95 he VTA may be important for the formation of drug-associated memory.

96 treatment of nonsteroidal anti-inflammatory drug-associated mucosal injury.

97 ias as isoimmune, autoimmune (including some drug-associated neutropenias), and idiopathic (cases pos

98 ed receptor models that require formation of drug-associated nonconducting states with high affinity

99 and habitual drug seeking, the influence of drug-associated Pavlovian-conditioned stimuli on drug se

100 bular injury strongly suggest a mechanism of drug-associated podocyte and tubular toxicity.

101 No drug-associated side effects were observed.

102 bling IFN-alpha therapy continuation without drug-associated skin eruptions.

103 ring the development of addiction in humans, drug-associated stimuli acquire increasingly stronger in

104 Drug seeking under the control of drug-associated stimuli and its reinstatement after exti

105 locus in mediating the effects of previously drug-associated stimuli on subsequent drug-seeking behav

106 , combined with enhanced excitatory drive by drug-associated stimuli, contributes to the two cardinal

107 ein signaling in the PFC focuses behavior on drug-associated stimuli, while dysregulated PFC-accumben

108 ence of excitatory drive that is elicited by drug-associated stimuli.

109 the sensitivity of brain reward circuits to drug-associated stimuli.

110 ility to extinguish conditioned responses to drug-associated stimuli.

111 elapse often precipitated by the presence of drug-associated stimuli.

112 ed conditioned reinforcing properties of the drug-associated stimulus and thus its impact on the lear

113 gical and behavioral treatments that disrupt drug-associated stimulus memories could be beneficial in

114 s suggesting that rats avoided intake of the drug-associated taste cue because the value of the taste

115 liver disease/nonalcoholic steatohepatitis, drug-associated toxicities, and other metabolic/genetic

116 patients (12.5%) were removed from study for drug-associated toxicity (five thromboembolic events, on

117 he treatment of uveitis has been linked with drug-associated toxicity and adverse events (AEs).

118 anagement of chronic infection by decreasing drug-associated toxicity and improving quality of life w

119 Quinine is a common cause of drug-associated TTP-HUS and can cause death and chronic

120 t of the most and the most recent reports of drug-associated TTP-HUS are discussed: mitomycin C, cycl

121 A systematic analysis of reports of drug-associated TTP-HUS will be required to better under

122 cause of the high mortality and morbidity of drug-associated TTP-HUS.

123 in antimetastatic activity without producing drug-associated weight loss as observed with systemic ad

124 id (TA) is a non-steroidal anti-inflammatory drug associated with anti-tumorigenic and pro-apoptotic

125 ated the metabolic footprint of metformin, a drug associated with improved post-MI LV function in exp

126 When a drug associated with torsades de pointes was prescribed

127 of the interactions, as well as diseases and drugs associated with a single nucleotide polymorphism o

128 ug Administration (FDA)-approved peptidergic drugs associated with allergic-type injection-site react

129 agogues, including inflammatory peptides and drugs associated with allergic-type reactions.

130 Many drugs associated with autoimmunity are susceptible to ox

131 We found 14, 10, 7% of all drugs associated with colon, prostate, and breast cancer

132 sed AD risk, and use of cholesterol-lowering drugs associated with decreased risk.

133 Drugs associated with high rates of positive rechallenge

134 al corticosteroids alone, are oral antiviral drugs associated with improved outcomes when combined wi

135 ve affective biases following treatment with drugs associated with inducing negative affective states

136 All opioid drugs associated with mortality; most associated with wo

137 Are antiepileptic drugs associated with reduced pain intensity in patients

138 d MRGPRX2 are targets of many small-molecule drugs associated with systemic pseudo-allergic, or anaph

139 rt the notion that many of the antipsychotic drugs associated with the development of movement disord

140 t Reporting System database was searched for drugs associated with thrombocytopenia by use of data mi

141 arrhythmic drugs, especially amiodarone, and drugs associated with torsade de pointes may have contri

142 idine and clopidogrel, are the 2 most common drugs associated with TTP in databases maintained by the

143 1%) had taken quinine, and 7 had taken other drugs associated with TTP-HUS.

144 Opioids are the most common drugs associated with unintentional drug overdose.