ライフサイエンスコーパス: duct

1 ial fluid into the labyrinth of the salivary duct.

2 in beta-intercalated cells of the collecting duct.

3 expression in the inner medullary collecting duct.

4 bution to the luminal lineage and the mature duct.

5 ymphatic vessels and did not form a thoracic duct.

6 CHD) and in 0.8% of subjects into the cystic duct.

7 e used for prompt identification of the bile duct.

8 , from the proximal tubule to the collecting duct.

9 passing the stroma and reaching the prostate ducts.

10 edullary interstitium mediated by collecting ducts.

11 MUC5B more often filled CF submucosal gland ducts.

12 IRF6 in major and minor salivary glands and ducts.

13 ing may allow improved targeting to the bile ducts.

14 rosis of the intra- and/or extrahepatic bile ducts.

15 the epithelial cells lining these secretory ducts.

16 with dysplastic terminal end buds (TEB) and ducts.

17 sorbed from the loop of Henle and collecting ducts.

18 ults in a failure to establish acini but not ducts.

19 inactive when in proximity with neighboring ducts.

20 experimental data from guinea-pig pancreatic ducts.

21 ion of unrecognized secondary branch biliary ducts.

22 t) by the former and the uterus by Mullerian ducts.

23 nd appears important for shaping the forming ducts.

24 ocalized to the stroma surrounding acini and ducts.

25 ebaceous glands, taste buds, nails and sweat ducts.

26 ahepatic biliary tract and intrahepatic bile ducts.

27 al cells of the connecting tubule/collecting ducts.

28 t and early lesions are in "downstream" bile ducts.

29 al tubule-derived inner medullary collecting duct 3 cells and show that PI3K-C2alpha resides at the r

30 d1 on the NOD background produces early bile duct abnormalities, initiating a break in tolerance that

31 or, Foxc1, is obligate for appreciable sweat duct activity in mice.

32 <50 years old), and in patients with duct-to-duct anastomoses (P = 0.028).

33 r image quality parameters in the pancreatic duct and common bile duct by using a five-point scale.

34 e acids into the duodenum through the cystic duct and common bile duct system.

35 lated lymphatic vessels obstructing the bile duct and compound heterozygosity for collagen and calciu

36 atic artery is the main blood supply to bile duct and lack of adequate HA flow is thought to be a ris

37 , was inserted to the straight, dilated main duct and plastic stent(s) were inserted to the secondary

38 The number of connections between the bile duct and the lobular bile canalicular network by the can

39 ticity in the fate choice between collecting duct and ureter, and show that an environment rich in BM

40 epithelial progenitors forming a network of ducts and acini (secretory cells).

41 ro The inability to form structurally normal ducts and alveoli during pregnancy resulted in lactation

42 Liver-infiltrating Treg reside close to bile ducts and coculture with cholangiocytes or their superna

43 to experimental data obtained from isolated ducts and intact pancreas under a range of experimental

44 structures inside the mouse pinna, and sweat ducts and Meissner's corpuscle in the human fingertip sk

45 Consequently, lumens in ducts and secretory portions were dilated, and blisters

46 may result from stronger equatorial westerly ducts and subtropical jets during La-Nina and weaker dur

47 tify bipotent and multipotent progenitors in ducts and TDLUs, respectively.

48 man breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs).

49 ucts in humans and mice occluding pancreatic ducts and thereby driving pancreatic inflammation.

50 On embryonic day 15.5, mutant Mullerian ducts and Wolffian ducts have elongated but their duct t

51 , including constitutive monoterpenes, resin ducts and wood density, were higher in GB bristlecone an

52 tion tissue in the larynx, urethra, lacrimal duct, and external auditory canal.

53 rminal end bud (TEB), the growing tip of the duct, and incorporates morphometrics, region-specific pr

54 homeostasis, predominantly of the collecting duct, and regeneration.

55 ed thick ascending limb of Henle, collecting duct, and stroma; however, it disappeared in mature NP-d

56 are present in the canalicular network, bile ducts, and gallbladder.

57 Robert's uterus is a very rare mullerian duct anomaly which is characterised by septate uterus wi

58 Our results demonstrate that syngeneic bile duct antigens efficiently break immune tolerance of reci

59 Mechanical indentation of the membranous duct at high frequencies evokes traveling waves that mov

60 The secretory duct begins as buds of chitin at the apical surface of i

61 trunk' from one end of which true collecting duct branches radiate and induce nephron development in

62 promoting cell rearrangements in the nephric duct, but this method was unsuited to study individual c

63 h1(fl/fl) mice were similar to Fsp-Cre;SmoM2 ducts, but Fsp-Cre;SmoM2 outgrowths were not stunted, su

64 eters in the pancreatic duct and common bile duct by using a five-point scale.

65 Furthermore, bioengineered artificial ducts can replace the native CBD, with no evidence of ch

66 hip to the pathogenesis of human distal bile duct cancer (DBDC).

67 isk factor for developing an aggressive bile duct cancer, cholangiocarcinoma, in chronically infected

68 actic core biopsy showed a focus of invasive duct carcinoma, strongly positive for estrogen and proge

69 Intranodal lymphangiogram and thoracic duct catheterization was successful in all patients.

70 The treatment of common bile duct (CBD) disorders, such as biliary atresia or ischemi

71 ithms for diagnosis of malignant common bile duct (CBD) stenoses are complex and lack accuracy.

72 y, the duodenum, ampulla, distal common bile duct (CBD), or head of the pancreas.

73 voluted tubule (DCT) and cortical collecting duct (CCD) is highlighted by various water and electroly

74 mozygous deletion of ILK in renal collecting ducts (CD) of Ilk(fl/fl) ;Pkhd1-Cre mice caused tubule d

75 e HNF-1beta specifically in renal collecting ducts (CDs).

76 e effects of miRNA suppression in collecting ducts (CDs).

77 scently loaded ECVs into a kidney collecting duct cell line (mCCDC11) and into primary cells.

78 and WNK1 were observed in a human collecting duct cell line, while SPAK was unaltered.

79 t Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebra

80 later time points, showed reduced acinar-to-duct cell metaplasia.

81 ancreatic duct cells, challenges the role of duct cells as progenitors, and suggests a genetic mechan

82 for ALGS ductal paucity.The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acin

83 In vitro, Grhl2-deficient collecting duct cells displayed increased paracellular flux of sodi

84 Collecting duct cells expressing this mutation had moderate abnorma

85 bud developed kidney agenesis and collecting duct cells had severe cytoskeletal, adhesion and polarit

86 Primary human pancreas duct cells harbouring oncogenic KRAS and induced mutatio

87 TRIP13 in murine inner medullary collecting duct cells in the presence of hydrogen peroxide showed i

88 cells, inhibition of ERK phosphorylation in duct cells mitigated TGFbeta-induced upregulation of gro

89 s was detected within the graft's collecting duct cells using quantitative polymerase chain reaction

90 omplete loss of canonical Notch activity and duct cells within the liver and exocrine pancreas, where

91 e specification of the intrahepatopancreatic duct cells, challenges the role of duct cells as progeni

92 rogenitors that give rise to both acinar and duct cells, genetic ablation of SOX2 results in a failur

93 hought able only to generate hepatocytes and duct cells, only duct cells.

94 rane exosomes from mouse cortical collecting duct cells.

95 Na(+) transport in mouse cortical collecting duct cells.

96 ent ERK phosphorylation in benign pancreatic duct cells.

97 capable to differentiate into SG acinar and duct cells.

98 s of exosomes from mouse cortical collecting duct cells.

99 to generate hepatocytes and duct cells, only duct cells.

100 s, RPSD was draining into the common hepatic duct (CHD) and in 0.8% of subjects into the cystic duct.

101 elopment with highly disorganized pronephric duct cilia.

102 image quality for the pancreatic and common duct compared with that of RT SPACE despite 17-fold shor

103 e, obstructive jaundice due to external bile duct compression or rupture of the HAA into the biliary

104 Small and large intrahepatic bile ducts consist of small and large cholangiocytes, respect

105 he pronephric tubules but not the pronephric ducts, consistent with the tubular atrophy observed in t

106 that line intrahepatic and extrahepatic bile ducts, contribute substantially to biliary secretory fun

107 Leakage of bile from this network and ducts could be an important driver of toxicity.

108 nd direct bilirubin (DBIL) with minimal bile duct damage in the ANIT treated rats.

109 by increased periportal infiltrations, bile duct damage, granulomas and fibrosis.

110 ent to partially suppress the Jag1(+/-) bile duct defects.

111 During rotation, duct deformability extends the frequency bandwidth and e

112 ig shunt or a DS for cardiac conditions with duct-dependent pulmonary blood flow between January 2012

113 lalock-Taussig shunt or a DS in infants with duct-dependent pulmonary blood flow.

114 a rare progressive disorder leading to bile duct destruction; approximately 75% of patients have com

115 nse mutant of Jag1 (Jag1(Ndr)) disrupts bile duct development and recapitulates Alagille syndrome phe

116 , talins are essential for kidney collecting duct development through mechanisms that extend beyond t

117 h controls, although aortic isthmus/arterial duct diameter ratio was lower in fetuses with CoA than i

118 ncluded pancreatic gland texture, pancreatic duct diameter, intraoperative blood loss, pathologic fin

119 Bile duct differentiation, morphogenesis, and function were d

120 solid component (P = 0.014), main pancreatic duct dilatation of more than 5 mm (P < 0.001), and jaund

121 er MCN, solid component or mural nodule, and duct dilation.

122 65.5% were men, 89.8% had classical or large-duct disease, and 70.0% developed IBD at some point.

123 s to propel substrates through the TolC exit duct, driven by MacB mechanotransmission.

124 RNA sequencing of NOD.Abd3 common bile duct early in disease demonstrates upregulation of genes

125 ling acutely blocked both cell migration and duct elongation.

126 in the kidney proximal tubule and collecting duct epithelia, where it has an important role in amino

127 a direct functional link between collecting duct epithelial barrier characteristics, which appear to

128 nctional relevance of this strong collecting duct epithelial barrier is unresolved.

129 It is mainly found in bile duct epithelial cells, the intestinal tract, and the cer

130 rising from malignant transformation of bile duct epithelial cells.

131 The collecting duct epithelium forms tight junctions composed of barrie

132 computational model of guinea-pig pancreatic duct epithelium was developed to determine the transport

133 ignal-regulated kinase signaling in Wolffian duct epithelium was responsible for the retention of mal

134 and ventral lobes and periurethral prostatic ducts exhibited a nonmonotonic dose response with peak P

135 ectomy (ERCP+LC) vs laparoscopic common bile duct exploration with laparoscopic cholecystectomy (LCBD

136 A left hepatectomy was done and dilated bile ducts filled with caseous necrotic material were seen in

137 oliferation and branching, producing stunted ducts filled with luminal cells showing altered ovarian

138 rmalities causing dependence on the arterial duct for pulmonary blood flow are often palliated with a

139 (s) inserted to the secondary branch biliary ducts for the treatment of anastomosis stricture after L

140 e cells continue to contribute to collecting duct formation during homeostasis.

141 r of hepatic arteries without affecting bile duct formation.

142 re of development of mesonephros/mesonephric duct gives rise to absent ureters and hence absent homol

143 ay 15.5, mutant Mullerian ducts and Wolffian ducts have elongated but their duct tips are enlarged an

144 , distal (non-hilar) obstruction of the bile ducts (HR 3.711, P=0.008), Bismuth-Corlette type IV stri

145 ed iNOS expression, liver fibrosis, and bile duct hyperplasia were significantly reduced in WT mice a

146 Mice lacking the inner medullary collecting duct (IMCD) urea transporter A1 (UT-A1) and urea transpo

147 in the intercalated cells of the collecting duct impaired acid-base regulation by the kidney.

148 segment 2 and 3 ducts joining the segment 4 duct in 67.8% of subjects.

149 IRE induces sufficient local heating to bile ducts in 24% of ablations.

150 We thus suggest that elimination of Wolffian ducts in female embryos is actively promoted by COUP-TFI

151 that such aggregates form inside pancreatic ducts in humans and mice occluding pancreatic ducts and

152 und that MUC5B emerged from submucosal gland ducts in the form of strands composed of multiple MUC5B

153 sigargin is likely to be stored in secretory ducts in the roots.

154 te to severe (<50% of portal areas with bile ducts) in 14 and mild (50%-75%) in 12.

155 cause the male reproductive tracts (Wolffian ducts) in the female degenerate owing to a lack of andro

156 usion of Na-taurocholate into the pancreatic duct induced necrotizing pancreatitis in the head of pan

157 dicated in the management of iatrogenic bile duct injuries (IBDI), but occasionally, it becomes the o

158 es to block progression of intrahepatic bile duct injury in patients with BA.

159 production and ameliorated intrahepatic bile duct injury.

160 m retrograde flow of chyle from the thoracic duct into lymphatic tributaries with defective valves.

161 promotes differentiation of early collecting ducts into uroplakin-positive, unbranched, ureter-like e

162 tle is known about the development of branch duct intraductal papillary mucinous neoplasms (BD-IPMNs)

163 ze (73%), and arose in the setting of a main duct IPMN (96%).

164 h retrograde flow of chyle from the thoracic duct is considered a potential mechanism underlying chyl

165 s highly expressed throughout the collecting duct; is modulated in abundance by vasopressin; interact

166 attern was a common trunk of segment 2 and 3 ducts joining the segment 4 duct in 67.8% of subjects.

167 The cystic-common bile duct junction was visualized before Calot triangle disse

168 secretory portion and an upper reabsorptive duct leading to the secretory pore in the skin.

169 eases proportionally to the increase in bile duct length, suggesting that no novel connections are es

170 l duct (RPSD) draining into the left hepatic duct (LHD) in 27.6% of subjects.

171 In this study, cirrhotic bile duct ligated (BDL) rats with PH were treated with Inflix

172 Bile duct-ligated (BDL) and sham-treated rats were imaged 19

173 liary hyperplasia and liver fibrosis in bile-duct-ligated (BDL) rats; however, no information exists

174 KCa3.1 inhibition were investigated in bile duct-ligated and carbon tetrachloride intoxicated rats.

175 ary hyperplasia was induced in rats via bile duct ligation (BDL) surgery, and galanin was increased i

176 and MCs infiltrate the liver following bile duct ligation (BDL), increasing intrahepatic bile duct m

177 thogenesis of liver fibrosis induced by bile duct ligation (BDL).

178 acute cholestatic liver injury, partial bile duct ligation (pBDL), with a novel longitudinal bioimagi

179 Here we used long-term partial pancreatic duct ligation (PDL) as a model to study CPRD.

180 cerebral cortex using rat models of HE (bile duct ligation [BDL] and induced hyperammonemia) and also

181 rtal hypertension was established using bile duct ligation in rats.

182 FRalpha in murine carbon tetrachloride, bile duct ligation, and 0.1% 3,5-diethoxycarbonyl-1,4-dihydro

183 iliary cirrhosis was induced in rats by bile duct ligation, and portal hypertension was induced by pa

184 dels of chronic liver injury, including bile duct ligation, nonalcoholic steatohepatitis, and obese m

185 al glands are capable of tissue repair after duct ligation-induced injury, likely involving resident

186 bit model with lacrimal gland main excretory duct ligation-induced injury.

187 mice increased significantly following bile-duct ligation.

188 in two separate murine models: CCl4 and bile duct ligation.

189 elopment of sickness behavior following bile-duct ligation.

190 r fibrosis induced by CCl4 treatment or bile duct ligation.

191 We performed bile-duct ligations or sham surgeries on C57BL/6 or toll-like

192 efficiently converted human acinar cells to duct-like cells (AD) in a SMAD-dependent manner, highlig

193 gether with the appearance of ectopic cystic duct-like epithelia in their gallbladders.

194 emonstrate that ECOs self-organize into bile duct-like tubes expressing biliary markers following tra

195 r and pancreas can rescue Notch activity and duct lineage specification in adjacent cells lacking jag

196 are directly and solely responsible for all duct lineage specification in these organs in zebrafish.

197 ma consists of collecting ducts and terminal duct lobular units (TDLUs).

198 = 363) were scored for the presence of bile duct loss and assessed for clinical and laboratory featu

199 Bile duct loss during acute cholestatic hepatitis is an omino

200 Bile duct loss during the course of drug-induced liver injury

201 -supplement-associated liver injury had bile duct loss on liver biopsy, which was moderate to severe

202 actor of poor outcome was the degree of bile duct loss on liver biopsy.

203 Compared to those without, those with bile duct loss were more likely to develop chronic liver inju

204 liver injury with histologically proven bile duct loss.

205 e pancreas and a non-dilated main pancreatic duct (<5 mm).

206 In summary, Foxc1 regulates sweat duct luminal cell differentiation, and mutant mice mimic

207 cyte terminal differentiation markers in the duct luminal cells, which most likely contribute to kera

208 ithelium cross-talk responsible for Wolffian duct maintenance.

209 Collecting ducts make up the distal-most tubular segments of the ki

210 5, by the expression of liver progenitor and duct markers, and by low expression of hepatocyte marker

211 ligation (BDL), increasing intrahepatic bile duct mass (IBDM) and fibrosis.

212 ucinous neoplasms (IPMNs) involving the main duct (MD IPMNs) or the main and branch ducts (mixed IPMN

213 threonine kinase 11), in the fetal Mullerian duct mesenchyme (MDM), the caudal remnant of which is th

214 ter transcription factor II) in the Wolffian duct mesenchyme became intersex-possessing both female a

215 main duct (MD IPMNs) or the main and branch ducts (mixed IPMNs) of the pancreatic system is a main p

216 The duct morphogenesis process was interrupted by inhibiting

217 ive imaging method for demonstration of bile duct morphology, which is useful to plan complex surgeri

218 f the pancreatic system is a main pancreatic duct (MPD) diameter of 5.0 mm or greater on computed tom

219 In collecting duct (mpkCCD) cells, acetazolamide reduced the cellular

220 The incidence of acquired nasolacrimal duct obstruction (NLDO) increases with age.

221 a secondary to primary acquired nasolacrimal duct obstruction (PANDO) and evaluate its outcomes.

222 r survival is also determined by distal bile duct obstruction, Bismuth- Corlette type IV stricture, b

223 procedure in the management of nasolacrimal duct obstructions.

224 as Roux-en-Y hepaticojejunostomy (vs duct-to-duct) (odds ratio, 3.06; 95% confidence interval, 1.52-6

225 thelia and basolaterally in the reabsorptive duct of human sweat glands.

226 proliferation of neoplastic cells within the duct of the mammary gland that have not invaded into the

227 t tracer revealed that lymph in the thoracic duct of these mice could enter the thoracic cavity by re

228 Ducts of Fsp-Cre;Ptch1(fl/fl) mice were similar to Fsp-C

229 activated NF-kappaB and GDF-15 in epithelial ducts of human pancreatic adenocarcinoma supports the im

230 In a separate set of experiments, bile ducts of male Wistar rats were exteriorized, allowing re

231 rdingly, stroma adjacent to invading mammary ducts of Sharpin(cpdm) mice displayed reduced collagen a

232 ammatory cholangiopathy (disease of the bile ducts) of unknown pathogenesis.

233 splant infection that disseminated to biliar duct or lung in 9% of patients.

234 nd are distributed sporadically to branching ducts or alveoli.

235 f breast tissue as either skin, fat, glands, ducts or connective tissue was demonstrated with an over

236 Upper tropospheric equatorial westerly ducts over the Pacific Ocean are the preferred location

237 roliferation is universal at diagnosis, bile duct paucity develops later.

238 und, Jag1 haploinsufficiency results in bile duct paucity in mice.

239 Liver duct paucity is characteristic of children born with Ala

240 rane of polarized murine cortical collecting duct principal cells.

241 response and/or direct effect on collecting duct principal or intercalated cells may underlie the re

242 /kg) every 4 days for 28 days exhibited bile duct proliferation and pericholangitis.

243 While intrahepatic bile duct proliferation is universal at diagnosis, bile duct

244 Rather, bile duct proliferation underpinned the increased fibrosis in

245 ptor 1 (GPBAR1) agonist associated with bile duct proliferation.

246 angitis via immunization with syngeneic bile duct protein (BDP).

247 us, low-level transfection of the collecting duct, proximal tubule, distal tubule, interstitial cells

248 alyses assessing the primary endpoint, small-duct PSC characterized a low-risk phenotype in both sexe

249 Small-duct PSC was associated with a lower risk of LTD or mali

250 CC1), assumed to be present in rat and mouse ducts, raised intracellular Cl(-) and resulted in a lowe

251 ry strictures in younger donors with duct-to-duct reconstruction and lower graft survival.

252 prosensory domain of the developing cochlear duct relies on the temporal and spatial regulation of th

253 highly reproducible sequence of interlobular duct remodeling, where cholangiocyte proliferation initi

254 to prevent complications, if a previous bile duct repair was attempted.

255 ties that produce the acini and higher order ducts, respectively.

256 The branching pattern of the right hepatic duct (RHD) was typical in 55.3% of subjects.

257 common variant was right posterior sectoral duct (RPSD) draining into the left hepatic duct (LHD) in

258 hydatid disease, cyst rapture into the bile ducts should be included in the differential diagnosis e

259 aphics, comorbidities, pathology, pancreatic duct size, pancreas texture, or operative technique.

260 C3 cells, which remained confined within the ducts so that primary cancer did not develop.

261 Here, we report that collecting duct-specific deletion of an epithelial transcription fa

262 In all models, IPMNs and PDAC expressed the duct-specific lineage tracing marker yellow fluorescent

263 oped autoantibodies targeting the collecting duct-specific water channel aquaporin 2, whereas autoant

264 Duct stenting (DS) is emerging as one such alternative w

265 ymphatic embolization procedures or thoracic duct stenting with covered stents to exclude retrograde

266 ven prior images had evidence of common bile duct stones (CBDS).

267 associated with development of dominant bile duct strictures (P = 0.02).

268 s (CIs) were determined for the rate of bile duct strictures, incomplete ablation, and tumor recurren

269 ely more differentiated hepatocytes and bile duct structures.

270 initially causes corrugation of the luminal duct surface, leading to an approximately five-fold incr

271 , but can be an indication of vanishing bile duct syndrome (VBDS).

272 The semicircular duct system is part of the sensory organ of balance and

273 and acid-base homeostasis in the collecting duct system of the kidney require an overlapping set of

274 sing operations within a continuous enclosed duct system, which may include cryogenic fuel-filling, a

275 enum through the cystic duct and common bile duct system.

276 iched gene sets in the developing collecting duct system.

277 the kidney with dilatation of the collecting ducts, systemic hypertension, and progressive renal insu

278 nts (8%) with traumatic leak from a thoracic duct (TD) branch, 14 patients (56%) with pulmonary lymph

279 nects these chitin buds to form a contiguous duct that largely separates from the apical surface duri

280 auses atresia of the homolateral ejaculatory duct that results in obstruction of the proximally place

281 And, how does the salivary duct, the structure through which saliva and parasites e

282 and Wolffian ducts have elongated but their duct tips are enlarged and fail to merge with the urogen

283 y of the system, causing a nearby collecting duct to develop into a uroplakin-positive, broad, unbran

284 with the MacA adaptor protein and TolC exit duct to drive efflux of antibiotics and enterotoxin STII

285 donors (<50 years old), and in patients with duct-to-duct anastomoses (P = 0.028).

286 of biliary strictures in younger donors with duct-to-duct reconstruction and lower graft survival.

287 months was Roux-en-Y hepaticojejunostomy (vs duct-to-duct) (odds ratio, 3.06; 95% confidence interval

288 iated barrier components, reduced collecting duct transepithelial resistance, and defective renal med

289 ons arranged around a symmetrical collecting duct tree that has no ureter.

290 iments with a catheter in the common hepatic duct was 25% of that in experiments without a catheter (

291 Retention of Wolffian ducts was not caused by ectopic androgen production or a

292 ges in sodium transport along the collecting duct were also observed.

293 Morphologic analysis revealed that sweat ducts were blocked by hyperkeratotic or parakeratotic pl

294 Adjacent intrahepatic bile ducts were dilated.

295 l prostate lobes plus periurethral prostatic ducts were evaluated at 7 mo or 1 y of age without or wi

296 se they can occlude secondary branch biliary ducts when placed above the biliary bifurcation.

297 lightly in the cortical/medullary collecting duct, whereas BK channel abundance increased in principa

298 and cessation of support to paramesonephric ducts which leads to unfused uterus (uterus didelphys).

299 on of protein plugs and viscous mucus in the ducts, which could otherwise lead to pancreatic disease.

300 tion speeds from rear to front of elongating ducts, with the front characterized by both high pERK an

301 ed from an efficient packing of the cochlear duct within the petrous bone.