ライフサイエンスコーパス: ductus

1 itum (dpc) in the mesenchyme surrounding the ductus.

2 ement using INDO or surgical ligation of the ductus.

3 very 12 hours x 3 in an attempt to close the ductus.

4 produced greater relaxation in the immature ductus.

5 lective EP receptor agonists in the immature ductus.

6 l persists in the smooth muscle layer of the ductus and immunostaining colocalizes with SM2 expressio

7 h with congestive heart failure from a large ductus, and one lamb was electively euthanized 5 days af

8 , atrial septal defects (20/47, 43%), patent ductus arteriosus (16/47, 34%), persistent left superior

9 The narrowest diameter of the ductus arteriosus (4.3 +/- 0.4 mm vs. 6.9 +/- 2.6 mm, p

10 o [AOR], 0.81; 95% CI, 0.67-0.98) and patent ductus arteriosus (AOR, 0.74; 95% CI, 0.62-0.89).

11 Neural crest-derived SMCs populating the ductus arteriosus (DA) and great arteries exhibited a ce

12 How the ductus arteriosus (DA) closes at birth remains unclear.

13 Wild-type embryonic ductus arteriosus (DA) exhibited high levels of PRDM6, w

14 The ductus arteriosus (DA) is a vessel whose patency is requ

15 Closure of the ductus arteriosus (DA) is essential for the transition f

16 The ductus arteriosus (DA) of newborn infants exposed in ute

17 as in the fetus, PGs maintain patency of the ductus arteriosus (DA), a vascular shunt that transmits

18 occurs is the closure and remodeling of the ductus arteriosus (DA), an arterial connection in the fe

19 placental mammals depends on closure of the ductus arteriosus (DA), an arterial connection in the fe

20 tic change that occurs is the closure of the ductus arteriosus (DA), an arterial connection in the fe

21 nd neonate, including adverse effects on the ductus arteriosus (DA).

22 Fetal aortic and pulmonary valve; ductus arteriosus (DA); and right (RPA), left (LPA), and

23 ation was observed between PM(10) and patent ductus arteriosus (for an interquartile range increase i

24 of buttoned device (BD) occlusion of patent ductus arteriosus (PDA) in a large number of patients wi

25 us for the screening and treatment of patent ductus arteriosus (PDA) in extremely preterm infants.

26 Nonsyndromic patent ductus arteriosus (PDA) is a common congenital heart def

27 Patent ductus arteriosus (PDA) is a common congenital heart dis

28 Patent ductus arteriosus (PDA) is a relatively common form of c

29 Patent ductus arteriosus (PDA) is associated with increased mor

30 Observational studies have associated patent ductus arteriosus (PDA) ligation among preterm infants w

31 Patent ductus arteriosus (PDA) poses a diagnostic and therapeut

32 rformed to determine the frequency of patent ductus arteriosus (PDA) reopening and the factors that m

33 may undergo palliation with either a patent ductus arteriosus (PDA) stent or a modified Blalock-Taus

34 theter closure of a moderate to large patent ductus arteriosus (PDA) using conventional techniques is

35 The patent ductus arteriosus (PDA) was the first congenital heart l

36 ne atrial septal defect (ASD) and two patent ductus arteriosus (PDA) were missed by DSCT.

37 We found that patent ductus arteriosus (PDA), a common congenital heart disea

38 il occlude the moderate to large size patent ductus arteriosus (PDA).

39 ), coarctation of the aorta (CoA) and patent ductus arteriosus (PDA).

40 eceiving indomethacin (INDO) to close patent ductus arteriosus (PDA).

41 neurysmal dilatation of the aorta and patent ductus arteriosus (PDA).

42 ut died prior to postnatal day 3 from patent ductus arteriosus (PDA).

43 locus at 16p for TAAD associated with patent ductus arteriosus (PDA).

44 eptal defect (ASD); device closure of patent ductus arteriosus (PDA); pulmonary valvuloplasty; aortic

45 use of Gianturco coils to close large patent ductus arteriosus (PDAs) (> or = 3.5 mm) and describes t

46 right and left pulmonary arteries (QP), and ductus arteriosus (QDA) were calculated in 63 normal fet

47 ect (aORs ranging from 1.29 to 2.17), patent ductus arteriosus [aORs = 1.54, 1.63; 95% confidence int

48 PGT plays a critical role in closure of the ductus arteriosus after birth by ensuring a reduction in

49 etal ductus arteriosus and in closure of the ductus arteriosus after birth.

50 normal patterning and differentiation of the ductus arteriosus and adjacent descending aorta.

51 differentiation in the vascular wall of the ductus arteriosus and adjacent descending aorta.

52 In other areas, such as patent ductus arteriosus and atrioventricular septal defect, th

53 banding with catheterization stenting of the ductus arteriosus and balloon atrial septostomy, especia

54 l relationship exists between patency of the ductus arteriosus and chronic lung disease and other mor

55 h epilepsy and other signs, including patent ductus arteriosus and coagulopathy, while hemizygous mal

56 Patent ductus arteriosus and coarctation of aorta occurred >3 t

57 All patients had persistent ductus arteriosus and congenital mydriasis, and variable

58 al valve inflow and direction of flow in the ductus arteriosus and descending aorta were unrelated to

59 599+1delG) was identified in familial patent ductus arteriosus and found to disrupt normal splicing o

60 ole both in maintaining patency of the fetal ductus arteriosus and in closure of the ductus arteriosu

61 riosus to close after birth is termed patent ductus arteriosus and is one of the most common congenit

62 oth muscle differentiation in the developing ductus arteriosus and may promote precocious expression

63 cular interest because it also causes patent ductus arteriosus and moyamoya disease.

64 s describing an association between a patent ductus arteriosus and the development of morbidities, su

65 Therapies designed to close the ductus arteriosus are contraindicated in some settings a

66 Much of the normoxic contraction of the ductus arteriosus at birth is related to calcium entry t

67 Closure of the ductus arteriosus at birth, essential for postnatal adap

68 ambs (126+/-3 d; 147 d, term) we ligated the ductus arteriosus at surgery, and treated animals with e

69 re infants with than in those without patent ductus arteriosus because afterload is lower in the form

70 ation, P62R, had a high prevalence of patent ductus arteriosus but had only mild abnormalities of fac

71 y intense beta-gal staining localizes to the ductus arteriosus but is absent or minimal in the pulmon

72 ght to establish and maintain patency of the ductus arteriosus by a new method of transvascular forma

73 ion of this pathway may contribute to patent ductus arteriosus by affecting the development of smooth

74 nificant role in control of major vessel and ductus arteriosus caliber in the rat fetus.

75 In the vast majority of infants, the ductus arteriosus closes by 3 days of life.

76 erization of PGHS1-PGHS2 may explain how the ductus arteriosus closes normally at birth in mice expre

77 Incidence of spontaneous ductus arteriosus closure was increased, likely contribu

78 To determine the role of PGT in ductus arteriosus closure, we used a gene-targeting stra

79 ghts into the genetic programs that underlie ductus arteriosus development and closure.

80 y artery diameter Z score <or=-2.5 or patent ductus arteriosus diameter <or=2 mm was 97% sensitive an

81 nly one infant required ligation of a patent ductus arteriosus during ECMO.

82 r morphogenetic development of the aorta and ductus arteriosus during embryonic and postnatal surviva

83 oth muscle layers of the tunica media in the ductus arteriosus exhibit positive beta-gal staining.

84 amicin clearance was decreased in the patent ductus arteriosus group vs. the control group (40.02 vs.

85 The infants with patent ductus arteriosus had higher values for ventricular perf

86 hough transcatheter coil occlusion of patent ductus arteriosus has gained popularity, few follow-up d

87 r the prevention and treatment of the patent ductus arteriosus have not documented a decrease in the

88 transcription factor associated with patent ductus arteriosus in humans, was uniquely expressed in m

89 ms underlying O2-induced constriction of the ductus arteriosus in late-gestation fetal rabbits.

90 hysiologic flow across the atrial septum and ductus arteriosus in the human fetus.

91 Ligation of the ductus arteriosus in utero produces pulmonary hypertensi

92 ) receptor antagonist, after ligation of the ductus arteriosus in utero.

93 the effector mechanism for O2 sensing in the ductus arteriosus involves the coordinated action of del

94 The ductus arteriosus is a specialized blood vessel containi

95 The ductus arteriosus is a vessel that connects the pulmonar

96 The ductus arteriosus is a vital fetal structure allowing bl

97 The ductus arteriosus is an arterial vessel that shunts bloo

98 opment and persists in the neonate until the ductus arteriosus is completely closed.

99 In the preterm newborn, a patent ductus arteriosus is in large part a result of the incre

100 an pulmonary artery pressure (PAP) 8 d after ductus arteriosus ligation (78+/-2, HTN vs. 70+/-4 mmHg,

101 Patent ductus arteriosus ligation among preterm neonates younge

102 Since the first patent ductus arteriosus ligation by Robert Gross of Boston in

103 All 14 premature infants undergoing patent ductus arteriosus ligation in a 1-year period at our ins

104 In preterm infants, patency of the ductus arteriosus may represent a normal physiologic ada

105 istance associated with ligation of a patent ductus arteriosus might worsen ventricular performance i

106 Patent ductus arteriosus occlusion can be accomplished by umbre

107 ersal of the physiologic shunting across the ductus arteriosus or atrial septum in utero (i.e., left

108 Patients with persistent ductus arteriosus or congenital mydriasis with a label o

109 Impaired development of the ductus arteriosus or disruption of signaling pathways th

110 olume of distribution was greater for patent ductus arteriosus patients (0.61 L/kg) than for controls

111 Maintaining patency of the ductus arteriosus postnatally is necessary with many for

112 r leukomalacia, chronic lung disease, patent ductus arteriosus requiring surgery, retinopathy of prem

113 Although a persistent patent ductus arteriosus results in diminished cardiac function

114 s been controversy as to whether or when the ductus arteriosus should be closed by either pharmacolog

115 ts who were delivered alive from the reverse ductus arteriosus shunt group and 4 of 12 from the rever

116 Reversed ductus arteriosus shunting was found with severe right h

117 Failure of the ductus arteriosus to close after birth is termed patent

118 ng should be altered in neonates with patent ductus arteriosus to reflect the impact of higher volume

119 t transvascular formalin infiltration of the ductus arteriosus wall has been applied successfully to

120 The ductus arteriosus wall was successfully infiltrated and

121 f transvascular formalin infiltration of the ductus arteriosus wall.

122 d cases regardless of whether preterm patent ductus arteriosus was included.

123 ts who required surgical closure of a patent ductus arteriosus was lower in the budesonide group than

124 ficant constriction of the great vessels and ductus arteriosus was observed with L-NIL, whereas both

125 A functionally closed ductus arteriosus was traversed with a specially designe

126 asthma, smoking in the household, and patent ductus arteriosus were predictive of wheezing in the pre

127 Necropsy revealed patent ductus arteriosus with normal intimal thickening but dil

128 21, 261); superior vena cava, 137 (77, 197); ductus arteriosus, 187 (109, 265); descending aorta, 252

129 4 with atrial septal defects, 2 with patent ductus arteriosus, 2 with tetralogy of Fallot, and 1 wit

130 ransposition of the great vessels, 3 patient ductus arteriosus, 3 partial anomalous pulmonary venous

131 1 (29, 53); superior vena cava, 29 (15, 43); ductus arteriosus, 41 (25, 57); descending aorta, 55 (35

132 ngenital heart disease that results when the ductus arteriosus, a muscular artery, fails to remodel a

133 and Cx43 knockout mice an attenuation of the ductus arteriosus, a phenotype which may be indicative o

134 ending, transverse and descending aorta, the ductus arteriosus, and across the aortic and mitral valv

135 comitant cardiac lesion, for example, patent ductus arteriosus, and aortic cross-clamp time were dete

136 ents with interatrial communications, patent ductus arteriosus, and pulmonary artery stenosis requiri

137 ung age at angioplasty, presence of a patent ductus arteriosus, and the diameters of the aortic isthm

138 on being stenting or stent redilation of the ductus arteriosus, balloon aortic valvuloplasty, and ste

139 onates subsequently diagnosed to have patent ductus arteriosus, based on clinical suspicion and echoc

140 and atrioventricular septal defects, patent ductus arteriosus, bicuspid aortic valve, and coarctatio

141 are common after coil embolization of patent ductus arteriosus, but most close spontaneously.

142 dysmorphology, osteochondrodysplasia, patent ductus arteriosus, cardiomegaly, pericardial effusion, a

143 somal dominant trait characterized by patent ductus arteriosus, facial dysmorphism and hand anomalies

144 in cardiopulmonary defects, including patent ductus arteriosus, in 30 to 40% of the mice.

145 rses of gentamicin were administered (patent ductus arteriosus, n = 106; control, n = 216).

146 n with secundum atrial septal defect, patent ductus arteriosus, or pulmonic stenosis have had infecti

147 fetal development, a specialized vessel the ductus arteriosus, shunts blood from the pulmonary arter

148 septal defects, patent foramen ovale, patent ductus arteriosus, stent placement for pulmonary artery

149 sure can result in persistent patency of the ductus arteriosus, the third most common congenital hear

150 increase in oxygen causes contraction of the ductus arteriosus, thus diverting blood flow to the lung

151 ion, hypoplastic left heart syndrome, patent ductus arteriosus, valvar pulmonary stenosis, tetralogy

152 rsistent left superior vena cava, and patent ductus arteriosus, were present in 32% of patients.

153 opment of better therapy to close the patent ductus arteriosus, which constitutes approximately 10% o

154 n was a useful marker for presence of patent ductus arteriosus, with a 92% specificity for patent duc

155 all groups, as was acute constriction of the ductus arteriosus.

156 ung disease, there is delayed closure of the ductus arteriosus.

157 nt, despite success in closure of the patent ductus arteriosus.

158 ous lobar pulmonary veins or a silent patent ductus arteriosus.

159 on (PPHN) following prenatal ligation of the ductus arteriosus.

160 ension (PPHN) after prenatal ligation of the ductus arteriosus.

161 rta, suggesting little effect on tone of the ductus arteriosus.

162 neonates without clinically suspected patent ductus arteriosus.

163 predictive value for the presence of patent ductus arteriosus.

164 rteriosus, with a 92% specificity for patent ductus arteriosus.

165 phy (RVH) caused by prolonged closure of the ductus arteriosus.

166 shed techniques for coil occlusion of patent ductus arteriosus.

167 ath or bronchopulmonary dysplasia and patent ductus arteriosus.

168 essels, SM2 is precociously expressed in the ductus arteriosus.

169 , we observe a strong beta-gal signal in the ductus arteriosus.

170 ed calcium channels, and constriction of the ductus arteriosus.

171 ribute to the unique muscle phenotype of the ductus arteriosus.

172 shunting following coil occlusion of patent ductus arteriosus.

173 h those of 14 preterm infants without patent ductus arteriosus.

174 e-dimensional image of the great vessels and ductus arteriosus.

175 d as they may cause premature closure of the ductus arteriosus.

176 atal necrotizing enterocolitis or persistent ductus arteriosus.

177 a Notch ligand, die postnatally from patent ductus arteriosus.

178 the development of smooth muscle within the ductus arteriosus.

179 of indomethacin to treat symptomatic patent ductus arteriosus.

180 and atrioventricular septal defects; patent ductus arteriosus; pulmonary stenosis; aortic stenosis;

181 rmore, SM2 expression can be detected in the ductus as early as 15.5 dpc.

182 3, and abnormal persistence of the bilateral ductus caroticus and right dorsal aorta.

183 domly assigned to delivery according to late ductus changes (133 [95%] of 140, 95%, 95% CI 90-98) wer

184 ated for sex, birth weight, gestational age, ductus closure, occurrence of NEC, bowel perforation, an

185 ethacin; we hypothesized that this is due to ductus constriction in utero, with subsequent remodeling

186 natally as the number of VSMCs necessary for ductus contraction increased.

187 Treatment of hamster ductus deferens (DDT1MF-2) cells and porcine aortic smoo

188 ryptorchidism and abnormal tortuosity of the ductus deferens, and female transheterozygotes exhibited

189 thelial cells of: lung, oviduct, epididymis, ductus deferens, and seminiferous tubules.

190 nal vesicle, bulbourethral gland, and caudal ductus deferens.

191 males at the junction of the epididymis and ductus deferens.

192 in Purkinje cell bodies and cells lining the ductus deferens.

193 4 receptor densities were higher in immature ductus, despite similar receptor mRNA and protein conten

194 The ductus differs primarily from the great vessels in that

195 pus bursa and the heavy muscular area of the ductus ejaculatorius simplex before and after mating, an

196 ells of reproductive tracts, the oviduct and ductus epididymis.

197 g and a vascular ring formed by a left-sided ductus from the descending aorta (n = 5); right aortic a

198 cacy of atrial septal defect devices, patent ductus occluders, and stents to treat coarctation of the

199 ly of atrial septal, ventricular septal, and ductus occluding devices shows particular promise.

200 Ductus relaxation and cAMP generation were augmented in

201 Surgical ligation and division of the ductus remains the gold standard for consistently achiev

202 ild-type protein in epigenetic regulation of ductus remodeling.

203 pressed in the urticulo-saccular foramen,the ductus reuniens, and Reissner's membrane, suggesting tha

204 Using ductus ring experiments, calcium imaging, reverse-transc

205 oxic contraction is an intrinsic property of ductus smooth muscle.

206 roduction, and isometric tension in rings of ductus taken from immature (65% gestation) and mature (9

207 or the increased sensitivity of the immature ductus to PGE2.

208 in the increased sensitivity of the immature ductus to PGE2: (1) increased cAMP production because of

209 of the increased sensitivity of the immature ductus to prostaglandin E2 (PGE2).

210 Absent ductus venosus (ADV) is a rare condition, but it should

211 Finally, we observed normal closure of the ductus venosus (DV) in DREC null mice.

212 ure of a hepatic vascular shunt known as the ductus venosus (DV).

213 patent developmental structure known as the ductus venosus (DV).

214 of a fetal hepatovascular shunt known as the ductus venosus (DV).

215 mutations in the Ahr locus display a patent ductus venosus and smaller livers throughout life.

216 d less blood away from the liver through the ductus venosus at 36 weeks gestation.

217 aimed to assess whether changes in the fetal ductus venosus Doppler waveform (DV) could be used as in

218 sing the tricuspid valve, foramen ovale, and ductus venosus Doppler).

219 imilar approach was used for measurements of ductus venosus flow.

220 The stream that originated from the narrowed ductus venosus had a higher velocity than that from the

221 is consistent with the existence of a patent ductus venosus in adult animals.

222 -type portal-caval, portohepatic, and patent ductus venosus patients had a successful 1-stage ligatio

223 This may be coupled with an increased ductus venosus shunt, the combination leading to a marke

224 eustachian valve and the septum primum, the ductus venosus stream preferentially passed through the

225 onstrated that ARNT hypomorphs have a patent ductus venosus, identical to that observed in the Ahr nu

226 ast echocardiography to evaluate flow in the ductus venosus, in both venae cavae, and through the for

227 s necessary for developmental closure of the ductus venosus, whereas AHR signaling in hepatocytes is

228 e of a fetal vascular structure known as the ductus venosus.

229 hunts (portohepatic), and 2 had a persistent ductus venosus.

230 At postmortem study, the ductus was patent, and histologic analysis showed variab

231 The ductus was then further dilated with either a 7- or 8-mm

232 isms involved in normoxic contraction of the ductus will permit the development of better therapy to