ライフサイエンスコーパス: duplicate

1 ources were reviewed, with data extracted in duplicate.

2 one reviewer, with a 10% sample extracted in duplicate.

3 reviewed and data extracted independently in duplicate.

4 s were identified and data were extracted in duplicate.

5 studies were abstracted independently and in duplicate.

6 Data extraction was done in duplicate.

7 and data extraction were independent and in duplicate.

8 ly continuous process by which the genome is duplicated.

9 n, orientation, termination, and presence of duplicates.

10 d duplicates that correspond to natural read duplicates.

11 search produced 2314 articles after removing duplicates.

12 e, resulting in retention of the majority of duplicates.

13 average effect on the sequence divergence of duplicates.

14 We screened 2555 new records after removing duplicates.

15 y could be a general property of tandem gene duplicates.

16 ccount for these errors when identifying PCR duplicates.

17 role that it plays in the evolution of gene duplicates.

18 ch contain a high proportion of natural read duplicates.

19 Excluding duplicates, 1,687 results were found, 60 of which were s

20 pth in the central North Pacific and amended duplicate 20 liter polycarbonate carboys with nitrate or

21 e have utilized a mouse model of autism that duplicates 6.3 Mb region of chromosome 7 (Dp/+) correspo

22 PCR mutagenesis protocol, which transiently duplicates a number of important cell division genes.

23 The recognition that the duplicated ACCase in Arabidopsis is an impediment to pla

24 1-resistant alleles, such as ace-1(V) or the duplicated ace-1(D) allele, currently spreading worldwid

25 ly, we find that genes that were retained as duplicates after the teleost-specific whole-genome dupli

26 ts into the evolutionary relationship of the duplicated alpha-gliadin genes were obtained from their

27 ignificantly reduced their risk of cancer by duplicating an important gene called TP53.

28 Experimental duplicate analyses of biological triplicates resulted in

29 W isotopes and on the basis of three or four duplicate analyses, the external reproducibility per ses

30 action and Synthesis: Data were extracted in duplicate and synthesized for meta-analysis using generi

31 damage to cells in the 8-cell embryo enabled duplicate and triplicate metabolic analysis of the same

32 ic and epigenetic information are faithfully duplicated and accurately transmitted to daughter cells

33 ges, supports the hypothesis that SNAPs were duplicated and derived from a common ancestor and unique

34 d early during unionid radiation, and that a duplicated and diverged atp8 gene evolved into the M-orf

35 A single Golgi stack is duplicated and partitioned into two daughter cells durin

36 ng evidence that Rj4 is Glyma.01g165800-D, a duplicated and unique version of Glyma.01g165800, that h

37 Extraction was done in duplicate, and risk of bias was assessed.

38 gnathsotome-like complement of edn and ednr duplicates, and these genes are expressed in patterns hi

39 In teleost fish, two distinct IGF-IR duplicates are conserved called IGF-IRa and IGF-IRb.

40 e placental mammals, possibly because tandem duplicates are coregulated by shared genomic elements.

41 However, most young duplicates are degraded by loss-of-function mutations, a

42 th the dosage-sharing hypothesis, most young duplicates are down-regulated to match expression levels

43 es, it is still largely unknown how new gene duplicates are initially fixed within populations and la

44 After whole-genome duplication, Rab GTPase duplicates are more highly retained than other genes in

45 Finally, reciprocally retained duplicates are often subject to dosage balance constrain

46 ansions, implying that some, but not all, TF duplicates are preferentially retained.

47 ipelines is PCR duplicate removal, where PCR duplicates arise from multiple PCR products from the sam

48 positive selection, the majority of retained duplicates arising from the younger mesopolyploidy WGD e

49 From title and abstract review, duplicated articles and obviously irrelevant studies wer

50 , the higher- and lower-expressing copies of duplicates as separate groups show broadly different res

51 ne and functional alterations that appear to duplicate aspects of the psychopathology of several neur

52 TL has 16 nucleotides of the 3' end duplicated at the 5' end and a 3' end produced by self-c

53 on activities of several closely related and duplicated BdDREB genes showed their functional divergen

54 ase within an Okazaki fragment is faithfully duplicated before dissociation but also necessitates an

55 me arms and aneuploidy where chromosomes are duplicated beyond normal diploid content.

56 nalysis resulted in the identification of 22 duplicated blocks and six tandem duplication events.

57 Two tandem duplicated but divergent IL-4/13 A isoforms and one IL-4

58 response to changes in luminal [Ca(2+)], was duplicated by exposing native RyR2 channels to subphysio

59 unction of the gene and whether the gene was duplicated by whole-genome duplication (WGD) or by small

60 ence datasets that accounts for natural read duplicates by leveraging heterozygous variants in an ind

61 borne flavivirus (Langat virus, LGTV) in the duplicated capsid gene region (DCGR).

62 also overlapping specificities and that the duplicated CELA3A and CELA3B isoforms did not evolve dis

63 d the platform through the identification of duplicated cell wall modules, and show that a lignin bio

64 been mostly related to the separation of the duplicated centrosomes and thereby to the assembly of a

65 Duplicated centrosomes are held together by a proteinace

66 Prior to mitosis, duplicated centrosomes are tethered together, which is t

67 osome maturation is the process by which the duplicated centrosomes recruit pericentriolar components

68 Seven ancestral blocks emerged from duplicated chromosome segments of 19 Spirodela chromosom

69 Thus, newborn cells inherit partially duplicated chromosomes.

70 Duplicating chromosomes once each cell cycle produces si

71 ordates, with apparent relaxation for highly duplicated clades.

72 ies-specific duplication events and tandemly duplicated clusters clearly demonstrated that species-sp

73 Skeletal Sr/Ca is indistinguishable between duplicate colonies of the same genotype cultured under t

74 BCGM divergence and expression difference of duplicate copies.

75 Using a duplicate copy of the pipo slip site region fused into a

76 aration method indicated that 45-50% of read duplicates correspond to natural read duplicates likely

77 hresholds throughout the brain, (4) included duplicated datasets, and (5) did not provide peak coordi

78 Subsequent amino acid substitutions in duplicated daughter genes selectively restricted protein

79 disabling mutation in one copy of a tandemly duplicated, diaphanous-related formin is perfectly assoc

80 and validated the results with the use of a duplicate diet analyses.

81 ry analyses and 935+/-329.9mg estimated by a duplicate diet analyses.

82 comparisons through diet diary analyses and duplicate diet for other elements showed good agreement,

83 that obtain through an elemental analysis of duplicate diets, with a mean+/-sd daily intakes of 956+/

84 sential process for the equal segregation of duplicated DNA into two daughter cells during mitosis.

85 several split modules and a large number of duplicated domains and domains predicted to be inactive.

86 VRN2 and SWINGER (SWN), and both genes were duplicated during a whole-genome duplication to generate

87 ranscriptional plasticity of genes that have duplicated during aphid evolution.

88 The central MTOC is the centrosome that duplicates during the cell cycle and assembles a bipolar

89 This has caused many duplicated efforts when integration is attempted between

90 NA sample, showing that it can find not only duplicated elements present in common databases but also

91 eficient for cooperative binding to tandemly duplicated elements, indicating that the L1 loop contrib

92 lective sweeps were enriched among polyploid duplicates encoding key developmental and physiological

93 identified 290 very recent small-scale gene duplicates enriched for sugar metabolism, fruit developm

94 ional factors and material properties before duplicating existing statutes.

95 is the first case of alternative splicing of duplicated exon in a mollusc that produces a novel varia

96 into tissue-specific subfunctionalization of duplicated exons in vertebrate evolution and expand the

97 oteins and glycosylation sites in biological duplicate experiments.

98 XTRACTION: Two authors independently, and in duplicate, extracted study characteristics, outcomes, as

99 We conducted duplicated factorial designed experiments producing tang

100 ical reproducibility was high, with ICCs for duplicate fecal samples between 0.64 and 1.00.

101 allows for the initial survival of mammalian duplicates, followed by slower functional adaptation ena

102 Fasting blood samples were measured in duplicate for glucose, triglyceride, and high-density li

103 ins gene families that are often retained in duplicate for periods extending to tens of millions of y

104 e retention, the properties that distinguish duplicate from singleton genes, and the evolutionary imp

105 computational methods do not distinguish PCR duplicates from "natural" read duplicates that represent

106 Gene duplicates from the paleohexaploid event were enriched f

107 gous mutations in human SMN1 Expression of a duplicate gene (SMN2) primarily results in skipping of e

108 ome-wide gene-body CG methylation (BCGM) and duplicate gene expression between a rice mutant null for

109 Comparisons of duplicate gene expression patterns across a wide range o

110 Here, we survey duplicate gene families and identify converted tracts in

111 Fractionation refers to the loss of duplicate gene pairs from one of the maize subgenomes du

112 as been invoked to explain these patterns of duplicate gene retention and loss.

113 The evolutionary mechanisms leading to duplicate gene retention are well understood, but the lo

114 fates of duplicate genes, models explaining duplicate gene retention, the properties that distinguis

115 The eel, however, contains a duplicate gene.

116 xpression patterns of 286 Arabidopsis lyrata duplicated gene groups and compared them with the respec

117 y correlates with the copy number of SMN2, a duplicated gene that is nearly identical to SMN1.

118 al without the presence of a quasi-identical duplicated gene, SMN2, specific to humans.

119 ning expression divergence between copies of duplicates generally holds for duplicates generated by w

120 een copies of duplicates generally holds for duplicates generated by whole genome duplication (WGD) o

121 The functional divergence of duplicate genes (ohnologues) retained from whole genome

122 emonstrated the dynamic functionalization of duplicate genes along the evolutionary time scale.

123 ary processes and functionalization of plant duplicate genes are associated with their ancestral func

124 noncoding sequences associated with retained duplicate genes from the ancient maize polyploidy.

125 a high rate of retention of extant pairs of duplicate genes have contributed to an abundance of dupl

126 We found that duplicate genes have more similar sequences than expecte

127 stigated the evolutionary processes of young duplicate genes in Arabidopsis.

128 nto the dynamic retention processes of young duplicate genes in plant genomes.

129 te genes have contributed to an abundance of duplicate genes in plant genomes.

130 Furthermore, duplicate genes tend to be initially expressed in pollen

131 To address the manner in which young duplicate genes were derived primarily from small-scale

132 plication mechanisms, the potential fates of duplicate genes, models explaining duplicate gene retent

133 ppreciated mechanism for the preservation of duplicate genes, namely preservation to limit expression

134 arking may facilitate long-term retention of duplicate genes.

135 rstanding the mutational processes affecting duplicate genes.

136 evolutionary processes for Arabidopsis young duplicate genes.

137 dundancy, which is frequently observed among duplicated genes (paralogs) with overlapping functions.

138 processes that have driven the retention of duplicated genes after recurrent WGDs.

139 DNA methylation and expression divergence of duplicated genes and suggested a role of epigenetic mech

140 nt increases in the expression levels of the duplicated genes and that these duplications are more li

141 Duplicated genes are a major contributor to genome evolu

142 (NCCs), in which neofunctionalization of the duplicated genes are thought to have facilitated develop

143 How these duplicated genes evolve and acquire the ability to speci

144 Following WGD, many of these duplicated genes evolved separate functions through subf

145 gements and higher frequency of retention of duplicated genes in soybean than in maize.

146 evolutionary fates of a set of four recently duplicated genes in soybean: FT2a, FT2b, FT2c and FT2d t

147 ion in spatiotemporal expression between the duplicated genes is more likely to be the outcome of neu

148 subsequent sub- and neofunctionalization of duplicated genes represent a major mechanism of plant ge

149 hii genome has a greater number of dispersed duplicated genes than other sequenced genomes and its ch

150 le of concerted divergence of simultaneously duplicated genes whose products function in the same com

151 found, decreases rapidly with the number of duplicated genes, complicating the application of such a

152 identified a suite of 47 genes, enriched for duplicated genes, with variants associated with spatial

153 are multiple possible evolutionary fates of duplicated genes.

154 ivergence is a previously unreported fate of duplicated genes.

155 h are then combined in order to disambiguate duplicated genes.

156 The duplicated genome size enlarged bark and wood layers in

157 s on soybean, a polyploid crop with a highly duplicated genome, relatively little public GBS data and

158 rtant model organisms, yet their ancestrally duplicated genomes sometimes complicate developmental ge

159 These duplicates have contributed to the evolution of novel fu

160 accession Cvi-0, one of the two copies of a duplicated histidine biosynthesis gene, HISN6A, is mutat

161 oidization shapes the expression patterns of duplicated homeologs.

162 ages used in this article are believed to be duplicated images.

163 Experiments were performed in duplicate in two independent centers using standard oper

164 g water-soluble mimetics and to more closely duplicate in vivo conditions.

165 that whole regions can be moved, removed or duplicated in bulk.

166 ss amyloid precursor protein (APP), which is duplicated in DS and in Ts65DN mice; however, normalizin

167 ne signaling is controlled by EIN2, which is duplicated in L. japonicus We obtained a L. japonicus Lj

168 t patients reveals that HYDIN2 is deleted or duplicated in most cases.

169 ndocytosis, but its performance has not been duplicated in red fluorescent protein scaffolds.

170 Moreover, KANK genes were further duplicated in teleosts through the bony-fish specific WG

171 ectrum, including its vibronic structure, is duplicated in the low-density limit.

172 ome is hindered by the large number of genes duplicated in Trisomy 21 and a lack of understanding of

173 These properdin-binding segments are duplicated in two mutant CFHR5 proteins, CFHR2-CFHR5Hyb

174 ther genomes, would shape the fate of tandem duplicates in evolution.

175 h the action of background selection against duplicates in functional regions of the genome.

176 tes with Picard or SAMTools, or left the PCR duplicates in the dataset.

177 be more frequently tandemly duplicated than "duplicates" in soybean, which may, to some extent, count

178 ication and the substrate preferences of the duplicated isoforms are unclear.

179 We identified 21 621 non-duplicate isolates of Enterobacteriaceae, Acinetobacter

180 a cell divides, it must not only accurately duplicate its genome but also recapitulate its programme

181 f read duplicates correspond to natural read duplicates likely due to fragmentation bias.

182 Duplicate loci that are highly differentiated between H.

183 hort-read sequencing data, we identified 744 duplicated loci in H. cydno and H. melpomene and evaluat

184 gories, including a higher proportion of WGD duplicates manifesting expression alteration, and differ

185 Duplicate mass spectrometric analyses and confirmatory n

186 ucibility: Bray-Curtis dissimilarity between duplicate measurements was 2.85 +/- 0.42% (mean +/- stan

187 transformed the maxillae into mandibles with duplicated Meckel's cartilage, which resulted in an abse

188 and characterize the genomic organization of duplicated metalloprotease genes (patristacins) recruite

189 can be attributed in part to variation in a duplicated nuclear gene (ACC2) that targets homomeric ac

190 mes project demonstrated that 70-95% of read duplicates observed in such datasets correspond to natur

191 shed model that erroneously harbors a tandem duplicate of the CAG repeat-containing exon, and a corre

192 e No-Rotation task, the correct choice was a duplicate of the study scene.

193 Our results suggest that the duplicates of alpha-gliadin and GLR genes have likely ta

194 Efference copies refer to internal duplicates of movement-producing neural signals.

195 studies, leaving 8378 (82%) after removal of duplicates, of which we reviewed 54 (26 [48%] were quant

196 Cooking was performed in duplicate on different days, under standardised conditio

197 specimens were fresh; 84/218 were tested in duplicate on Xpert to compare WB sampling methods (pipet

198 Like DNA, centrosomes are duplicated once each cell cycle.

199 The spindle pole body (SPB) of budding yeast duplicates once per cell cycle.

200 no acid sensor in all four grass species has duplicated only in Ae. tauschii and generated three more

201 which assemble in S phase) cannot themselves duplicate or organize centrosomes until they have passed

202 l of RNA transcription, and therefore tandem duplicate overactivity appears to be a previously uniden

203 n mutations, and the factors that allow some duplicate pairs to survive long-term remain controversia

204 33 studies remained following the removal of duplicates, papers unrelated to genetic childhood condit

205 reation of single crossover chimeras between duplicated paralogous genes is a known process for incre

206 eptors, and neofunctionalization of recently duplicated paralogs.

207 ene2function.de), enabling identification of duplicated pathways and conserved processes across 10 pl

208 ch create the unique situation in which such duplicated pathways or networks could evolve novel funct

209 hdrew immediately after randomization, and 1 duplicate patient was identified.

210 k height similarity to identify ion adducts, duplicate peak reports, and isotopic features of the mai

211 arch resulted in 3991 entries after removing duplicates, plus 20 other items found via references and

212 Although a considerable number of the older duplicates presented signatures of retention under posit

213 Molecular mechanisms mediating duplicate preservation remain incompletely understood.

214 Duplicate publication data, studies lacking data on SMR

215 We reveal the key molecular substitution in duplicated pyruvate dehydrogenase genes that underpins o

216 retinoic acid receptors (RARs) to either PD duplicate (RA treatment or RARgamma agonist) or truncate

217 imately 1,000-fold, decreasing discarded PCR duplicate reads by approximately 60% while maintaining s

218 iplexing, 5' and 3' PCR primer matching, and duplicate reads collapsing.

219 We identified 278 non-duplicate records, of which 107 full-text articles were

220 Our search identified 15 615 non-duplicate references, of which 113 were deemed potential

221 The duplicated region was further located to a position with

222 The retention of the duplicated Regions D and D' enables inversion of the syn

223 gene expression both within and outside the duplicated regions.

224 We extracted data, in duplicate, related to items of selection bias (sequence

225 Our results suggest that PCR duplicate removal has minimal effect on the accuracy of

226 , including linker trimming, read alignment, duplicate removal, peak calling and chromatin loop calli

227 One step in many pipelines is PCR duplicate removal, where PCR duplicates arise from multi

228 dup) are the two main softwares used for PCR duplicate removal.

229 ions and tumor classifications, and frequent duplicate reporting.

230 ospitalised patients or special populations, duplicate reports, interim reports superseded by a final

231 We excluded duplicate reports, trials of compound drugs, trials that

232 f the HCCs, the weak S45 mutant alleles were duplicated, resulting in a final high ss-catenin activit

233 ndependent gene lineages and are most likely duplicates retained uniquely in cyclostomes.

234 a large-scale study in which we investigated duplicate retention for 9178 gene families shared betwee

235 One class of models to explain duplicate retention invokes sub- or neofunctionalization

236 Duplicate retention is highly variable across species, w

237 al diversification of paralogues, we tracked duplicate retention patterns, expression-level divergenc

238 to be retained after the Ss4R, and that the duplicate retention was not influenced to a great extent

239 suggested a role of epigenetic mechanism in duplicate retention.

240 erved in such datasets correspond to natural duplicates sampled from genes with high expression and i

241 lable methods for both reproducibility among duplicate samples and accuracy of methylation measuremen

242 Duplicate samples as well as two individual NGS runs pro

243 procedures, which included the collection of duplicate samples of salt added to food at the table and

244 nces between the measured values for 100-200 duplicate samples, and through our use of surrogate (rec

245 n type bias, reducing technical variation in duplicate samples, improving accuracy of measurements ag

246 Two authors independently and in duplicate screened citations and reviewed text of studie

247 We identified duplicated screens using a library with 6 gRNAs per gene

248 Plants containing the duplicated segment exhibit dosage-dependent effects on e

249 essed genes and unique small RNAs within the duplicated segments exhibit dosage-dependent transcript

250 ication of the telomeric third of the Ts65Dn-duplicated sequence and demonstrate the same ODP defect,

251 We find evidence suggesting a duplicated sequence in the I. pulchra mitochondrial geno

252 seline rate, we show that NAGC slows down as duplicate sequences diverge-until an eventual "escape" o

253 leverages substantially more information in duplicate sequences than used by previous methods and us

254 ibility of a shared mechanism for generating duplicated sequences at breakpoints.

255 The first class duplicated sequences neighboring the deletion, restoring

256 These duplicated sequences were generated from sequences immed

257 atients and Methods Ten genes were tested in duplicate serum samples from 141 women at baseline, at w

258 s of purifying selection to their respective duplicates since these pairs were formed by a WGD event

259 t a nuclear pore complex associates with the duplicating SPB and helps to insert the SPB into the NE.

260 isolates and a center-dependent benefit for duplicate spotting (range, 2 to 8.7%).

261 egulatory proteins that were retained in the duplicated state after the whole genome duplication even

262 1126 articles reviewed, 598 were removed as duplicate studies and 524, for lack of monthly treatment

263 Duplicate studies and abstracts from scientific meetings

264 f long-range haplotyping through segmentally duplicated subtelomere regions.

265 expression domains and expression levels for duplicated teleost genes often approximate the patterns

266 Upon origination, duplicates tend to maintain their ancestral functions; b

267 dical shifts in the functional spectrum of a duplicated TF.

268 s" were found to be more frequently tandemly duplicated than "duplicates" in soybean, which may, to s

269 expression evolves slowly and is rare among duplicates that arose within the placental mammals, poss

270 asets and for assessing the fraction of read duplicates that correspond to natural read duplicates.

271 hat most reads targeting a specific exon are duplicates that have been amplified from the PCR step.

272 stinguish PCR duplicates from "natural" read duplicates that represent independent DNA fragments and

273 robability of recruiting DNMT1 to faithfully duplicate the DNA methylation profile.

274 nd CO2 from coal use, China is attempting to duplicate the rapid development of shale gas that has ta

275 (PL) region of the medial prefrontal cortex duplicated the effects of systemic ketamine, and, conver

276 DNA replication precisely duplicates the genome to ensure stable inheritance of ge

277 single pair of replisomes is responsible for duplicating the entire 4.6 Mbp circular chromosome.

278 When duplicated, the loxPint module serves as an intragenic r

279 Cells must duplicate their mass in order to proliferate.

280 We screened in duplicate, then extracted data and appraised risk of bia

281 In a broad range of taxa, genes can duplicate through an RNA intermediate in a process media

282 fter whole-genome multiplications but rarely duplicate through small-scale duplication, a pattern ref

283 Data were de-duplicated to determine a unique person count.

284 Twenty photograph pairs from each group were duplicated to determine reviewer variability.

285 receptor germ cell-expressed (gce) gene has duplicated to yield the paralog Methoprene-tolerant (Met

286 Here, we use the duplicate tuf genes in Salmonella as a quantitatively tr

287 e is co-opted from the gene sequence that is duplicated upon transposon insertion, allowing perfect s

288 We extracted data in duplicate using a standardised approach.

289 internal validity of trials was assessed in duplicate using the Cochrane Collaboration's Risk of Bia

290 affects regulatory strength, we generated a duplicated version of miniFH, termed midiFH.

291 es to learn about the evolutionary fate of a duplicated vertebrate genome in 70 extant lineages.

292 After removal of duplicates, we found 373 abstracts, 91 of which met our

293 After duplicates were excluded, 304 relevant articles were ass

294 r transcriptional regulation, whereas tandem duplicates were overrepresented by environmental respons

295 ish specific WGD, while only kank1 and kank4 duplicates were retained in some of the examined fish sp

296 extracted data and appraised risk of bias in duplicate with a pre-tested form.

297 riants called were called whether we removed duplicates with Picard or SAMTools, or left the PCR dupl

298 An open issue is whether these domains, when duplicated within the same parent protein, interact with

299 rmation resources for compilers, eliminating duplicated work and supporting unambiguous referencing o

300 nts, Tbx5 and nkx2-5, and identified sets of duplicated zebrafish genes that do not show temporal sub