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1 motor units are controlled within the outer dynein arm.
2 fects in ciliary structure, 66% in the outer dynein arm.
3 heavy chain that is a component of the inner dynein arm.
4 ubunit is an integral component of the outer dynein arm.
5 imately 1.0 x 10(-6) dyne (10 pN) per intact dynein arm.
6 d sequence of the 1alpha Dhc of the I1 inner dynein arm.
7 the alpha and beta heavy chains of the outer dynein arm.
8 tubules and the motor domain(s) of the outer dynein arm.
9 a reduction in the number of outer and inner dynein arms.
10 sult in loss of the spermatid axonemal outer dynein arms.
11 other essential for assembling the axonemal dynein arms.
12 ubules occur by cyclic cross-bridging of the dynein arms.
13 strains had defects in the f class of inner dynein arms.
14 ons are associated with defects in the outer dynein arms.
15 signals between the central microtubules and dynein arms.
16 liary dyskinesia caused by the loss of outer dynein arms.
17 the doublet and is linked to different inner dynein arms.
18 assembly and/or trafficking of the axonemal dynein arms.
19 ant cannot assemble any outer and some inner dynein arms.
20 d defects in the assembly of inner and outer dynein arms.
21 latory signals between the radial spokes and dynein arms.
22 mutants lacking C1d and distinct subsets of dynein arms.
23 ston's organ, the fly's auditory organ, lack dynein arms.
24 sed on sliding doublet microtubules by inner dynein arms.
25 arms, in which forces are generated by inner dynein arms.
26 ein, in between radial spoke 1 and the outer dynein arms.
27 of those strains that fail to assemble outer dynein arms.
28 nger flagella, but the flagella lacked outer dynein arms.
29 latory signals between the radial spokes and dynein arms.
30 ely affects CBF through direct influences on dynein arms.
31 ng because of loss of some but not all outer dynein arms.
32 ry complex (N-DRC) is proposed to coordinate dynein arm activity and interconnect doublet microtubule
35 2 is an essential subunit of flagellar outer dynein arms allows us to propose a detailed mechanism wh
36 Unlike the Tctex2 homologue within the outer dynein arm, analysis of a Tctex2b-null strain indicates
37 iliary outer dynein arm defects, fewer inner dynein arm and central apparatus defects (P<0.001), and
38 y chain genes: beta heavy chain of the outer dynein arm and heavy chain isotype 1B (DYH1B), by using
39 ally, in the pf13A mutant, which lacks outer dynein arms and inner dynein arm c, the estimates were E
40 onemes from mutants that lack both the outer dynein arms and the MIA complex, I1 dynein failed to ass
41 the chemomechanical energy conversion by the dynein arms and their orchestrated movement in cilia/fla
43 tein can be extracted from oda1 (lacks outer dynein arms) and pf17 axonemes with 0.5 M KI, and copuri
46 rmal with respect to the 9 + 2 microtubules, dynein arms, and radial spokes but one of the two centra
47 d to generate symmetric waveforms, the outer dynein arms are potential targets of the central pair-ra
48 o cilia and flagella, multi-subunit axonemal dynein arms are thought to be stabilized and pre-assembl
49 own of dnaaf3 in zebrafish likewise disrupts dynein arm assembly and ciliary motility, causing primar
51 chanisms critical for motile cilia function: dynein arm assembly for C21orf59 and assembly of the nex
52 Of the uncloned ODA genes required for outer dynein arm assembly in Chlamydomonas, ODA5 and ODA10 are
53 hat Pontin and Reptin function to facilitate dynein arm assembly in cytosolic foci enriched with R2TP
55 he cytoplasm of wild-type cells and 11 outer dynein arm assembly mutant strains (oda1-oda11) by Weste
56 down in zebrafish and planaria blocked outer dynein arm assembly, and ccdc65 knockdown altered cilia
59 2-1 axonemes exhibited a novel f class inner dynein arm biochemical phenotype; the 138-kD f intermedi
60 ysfunction of both flagellar inner and outer dynein arms but does not require the cytoplasmic isozyme
63 re appear to alter the activity of the outer dynein arms by modification of the gamma-dynein heavy ch
64 ant, which lacks outer dynein arms and inner dynein arm c, the estimates were EI = 777 +/- 184 pN.mum
65 e of ATP, the structural conformation of the dynein arms can be clearly resolved by negative contrast
67 r, whereas the expression levels of multiple dynein arm components remain unchanged or become elevate
75 h situs abnormalities had more ciliary outer dynein arm defects, fewer inner dynein arm and central a
76 rate that animals that completely lack outer dynein arms display a significant decline in beat freque
80 known subunits of the outer arm or the outer dynein arm-docking complex (ODA-DC), and because genetic
84 tex2b is required for the stability of inner dynein arm I1 and wild-type axonemal dynein function.
86 fects (ODA alone; n = 54) and ODA plus inner dynein arm (IDA) defects (ODA + IDA; n = 18) versus subj
87 as well as uniflagellate cells lacking inner dynein arms (ida3) or outer dynein arms (oda2) were stud
88 ects, often caused by dual loss of the inner dynein arms (IDAs) and outer dynein arms (ODAs), which p
94 e have analyzed the rescue of inner or outer dynein arms in quadriflagellate dikaryons by immunofluor
96 ong arm result in loss of the axonemal outer dynein arms in the spermatid tail, while three ks-2 alle
97 , but the lack of N-DRC (in pf3; cnk11-6) or dynein arms (in pf13A) significantly reduces interdouble
98 ule sliding in axonemes that also lack outer dynein arms, in which forces are generated by inner dyne
99 heir architecture, including partial loss of dynein arms, incomplete closure of the B-tubule, and occ
104 uorescence microscopy of p28(IDA4), an inner dynein arm light chain, or IC69(ODA6), an outer dynein a
106 he EST for the beta heavy chain of the outer dynein arm mapped to chromosome region 7p15, and the EST
107 isorder frequently caused by non-assembly of dynein arm motors into cilia and flagella axonemes.
109 respiratory pathogens in subjects with outer dynein arm (ODA) defects (ODA alone; n = 54) and ODA plu
118 Multiprotein complexes referred to as outer dynein arms (ODAs) develop the main mechanical force to
122 es, usually as a result of loss of the outer dynein arms (ODAs) that power cilia/flagella beating.
123 ss of the inner dynein arms (IDAs) and outer dynein arms (ODAs), which power cilia and flagella beati
129 omponent of the central pair, radial spokes, dynein arms, or structures defined by the mbo waveform m
130 evious studies, suggest that flagellar outer-dynein arms preassemble into a complete Mr approximately
133 domonas reinhardtii resulted in absent outer dynein arms, reduced flagellar beat frequency, and decre
134 enotypes that resembled those of known inner dynein arm region mutant strains, but did not have bioch
136 markably, mutations in either outer or inner dynein arm restore motility to mutants lacking C1d, alth
141 e into a complete Mr approximately 2 x 10(6) dynein arm that resides in a cytoplasmic precursor pool
143 , the demonstration of oscillatory forces in dynein arms, the determination of the force-velocity rel
144 incorporates discrete representations of the dynein arms, the passive elastic structure of the axonem
145 sely associated structures such as the inner dynein arms, the radial spokes, and the calmodulin- and
146 complex distorter, Tctex2, within the outer dynein arm, these results support the hypothesis that tr
147 ealed that LC7b interacts with LC3, an outer dynein arm thioredoxin; DC2, an outer arm docking comple
148 -associated structure that targets the outer dynein arm to its binding site on the flagellar axoneme.
149 m-docking complex (ODA-DC) targets the outer dynein arm to its correct binding site on the flagellar
151 lpha-tubulin or p28, a component of an inner dynein arm, which suggests specificity with respect to t
154 ecules involved in active transport of inner dynein arms within flagella we searched for polypeptides
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