ライフサイエンスコーパス: dyskinetic

1 be good apomorphine antagonists but all were dyskinetic.

2 ts N-2-(2-hydroxyethoxy)ethyl analogue 3 was dyskinetic.

3 zepines, 2 was not dyskinetic whereas 2a was dyskinetic.

4 m and a reduction in SN of both unprimed and dyskinetic 6-hydroxydopamine rats, consistent with oppos

5 equency significantly increased in ON L-DOPA dyskinetic 6-hydroxydopamine-lesioned rats, suggesting t

6 lidum does not separate antiparkinsonian and dyskinetic actions implies that they are closely related

7 size, percentage of the LV that was akinetic/dyskinetic (%AD), and LV shape index.

8 size (maximum dimension, 10 to 66 mm), were dyskinetic/akinetic with thin rims, and were associated

9 In the 'OFF' state withdrawn from levodopa, dyskinetic and non-dyskinetic patients had similar level

10 When dyskinetic and nondyskinetic patients were studied with

11 Dyskinetic and nondyskinetic PD patients were studied us

12 entially expressed between highly and weakly dyskinetic animals after treatment with L-DOPA.

13 y contact(i.e., multisynaptic spines) in the dyskinetic animals compared with the 6-hydroxydopamine-t

14 To test motor function and dyskinetic anomalies, we examined cylinder behaviour and

15 between 15% and 40%, and dilated akinetic or dyskinetic anterior-apical wall without the need to be r

16 area r=-0.51, P<0.0001; RVOT displacement of dyskinetic area r=-0.49, P<0.0001; and RVOT late gadolin

17 VOT ejection fraction r=0.64, P<0.0001; RVOT dyskinetic area r=-0.51, P<0.0001; RVOT displacement of

18 l extent of dyskinetic area, displacement of dyskinetic area, and score of extent of late gadolinium

19 gmental ejection fraction, spatial extent of dyskinetic area, displacement of dyskinetic area, and sc

20 Previously, only dyskinetic areas were treated by operation.

21 st, children with quadriplegic and mixed CP (dyskinetic, athetoid, hypotonic, and ataxic) more often

22 arcted segment is often akinetic rather than dyskinetic because early reperfusion prevents transmural

23 riatonigral medium spiny neurons exacerbated dyskinetic behavior, whereas overexpression of cJun, whi

24 and cocaine-induced locomotion and abolished dyskinetic behaviors in response to the Parkinson's dise

25 Tat-D2Ri also alleviated dyskinetic behaviors induced by levodopa.

26 ndrites that appear to be directly linked to dyskinetic behaviors, since they were not seen in the st

27 ic target for use in preventing or reversing dyskinetic behaviors.

28 irectionally and found them able to modulate dyskinetic behaviors.

29 ABA efflux, coincident with the emergence of dyskinetic behaviors.

30 dSPNs, enabled LTP reversal, and attenuated dyskinetic behaviors.

31 sensitive molecular response associated with dyskinetic behaviors.

32 uced striatal and thalamic opioid binding in dyskinetic, but not in nondyskinetic, PD patients.

33 Dyskinetic cerebral palsy (DCP) is the second most commo

34 normal airway epithelial cells had stiff and dyskinetic cilia beating patterns compared to control ce

35 y transmission electron microscopy, but with dyskinetic cilia beating.

36 at NMDA receptor blockade may ameliorate the dyskinetic complications of long-term levodopa therapy,

37 w, and comprised all infants with spastic or dyskinetic CP not caused by developmental abnormalities

38 children with moderate to severe spastic or dyskinetic CP not due to postnatal brain injury or devel

39 ral globus pallidus injury in the setting of dyskinetic CP.

40 Whereas DMI alone elicited no dyskinetic effects in lesioned rats, DMI + L-DOPA-treate

41 fficult to separate the antiparkinsonian and dyskinetic effects of levodopa.

42 Segmental shortening in the dyskinetic ischemic region improved only minimally at th

43 Dyskinesia and dyskinetic-like movements are more common in subjects wi

44 Spectrum subjects had more dyskinetic-like movements than normal subjects.

45 bjects with schizotypal personality had more dyskinetic-like movements than subjects with schizoid pe

46 Dyskinetic-like movements were assessed in 34 spectrum s

47 They also tested the hypothesis that dyskinetic-like movements would increase after repeated

48 of behavioral sensitization (an increase in dyskinetic-like movements), but spectrum subjects showed

49 subjects showed an abnormal response (fewer dyskinetic-like movements).

50 -4-phenyl-1,2,3,6-tetrahydropyridine-treated dyskinetic macaques without affecting the global parkins

51 this normalization of basal excitability, in dyskinetic mice, the selective D1R agonist SKF38393 incr

52 Hb was found to be metabolically modified in dyskinetic monkeys and its neuronal firing frequency sig

53 , to test the effect of grafts on previously dyskinetic monkeys.

54 e, consisting of transient attacks of severe dyskinetic motor behavior.

55 on within this network may contribute to the dyskinetic motor spasms.

56 ent displaying a disorder characterized by a dyskinetic movement disorder, developmental delay, and a

57 g this variant presented with an early onset dyskinetic movement disorder, severe motor delay, and pr

58 Dyskinetic movement scores correlated with positive symp

59 kinesia, as seen in Parkinson's disease, and dyskinetic movements as seen in Huntington's disease or

60 neurocircuitry hypothesized to give rise to dyskinetic movements has also been implicated in psychot

61 ine and l-dopa-induced normal ambulatory and dyskinetic movements in Pitx3 mutant mice, whereas the s

62 ggested to underlie dopamine-agonist-induced dyskinetic movements that develop during the treatment o

63 e of neural networks to suppress involuntary dyskinetic movements.

64 dorsal striatum may enhance both normal and dyskinetic movements.

65 dopamine agonist drugs are able to initiate dyskinetic movements.

66 euronal communication, with the emergence of dyskinetic movements.

67 Most hypokinetic and 40% of akinetic/dyskinetic myocardial segments contained scintigraphical

68 oxysmal episodes in puberty, either dystonic/dyskinetic or "shivering" attacks, triggered by stretchi

69 All monitored segments were either dyskinetic or akinetic during the 30-minute occlusion.

70 of left ventricular (LV) reconstruction for dyskinetic or akinetic LV segments in patients with isch

71 or bilateral spasticity, as in those with a dyskinetic or ataxic disability.

72 ography was performed in the 'ON' condition, dyskinetic patients had higher (11)C-CNS 5161 uptake in

73 withdrawn from levodopa, dyskinetic and non-dyskinetic patients had similar levels of tracer uptake

74 atients without dyskinesias, suggesting that dyskinetic patients may have abnormal glutamatergic tran

75 The role of glutamate function in dyskinetic patients with Parkinson's disease, however, i

76 ed prefrontal opioid receptor binding in the dyskinetic patients.

77 ether the opioid system is involved in human dyskinetic PD, we measured in vivo opioid receptor bindi

78 fidence in the Cebus model as a predictor of dyskinetic potential.

79 e for a dramatic rewiring of the striatum of dyskinetic rats and that this rewiring involves corticos

80 s overexpressed only on the lesioned side of dyskinetic rats in LHb and co-localized with DeltaFosB,

81 ession of FosB, ARC, Zif268 and FRA2 only in dyskinetic rats.

82 ration response, long-duration response, and dyskinetic response to levodopa change during long-term

83 y raise the possibility that the maladaptive dyskinetic responses to chronic l-DOPA treatment in Park

84 PNs oppositely modulate both therapeutic and dyskinetic responses to dopamine replacement therapy in

85 mice, hM3Dq stimulation of dSPNs exacerbated dyskinetic responses to L-DOPA, while stimulation of iSP

86 of 360 segments), especially in akinetic and dyskinetic segments (276 [91%] of 303), irrespective of

87 mber by excluding scar in either akinetic or dyskinetic segments.

88 A on the therapeutic parameters, but develop dyskinetic side effects.

89 l motor sensitization, but also develop less dyskinetic side effects.

90 nd might not be associated with debilitating dyskinetic side-effects after prolonged treatment.

91 ith drug effects, lead to the development of dyskinetic signs.

92 and ataxic) more often had high myopia, CVI, dyskinetic strabismus, and gaze dysfunction.

93 or high myopia, absence of binocular fusion, dyskinetic strabismus, severe gaze dysfunction, and opti

94 Patients with dyskinetic symptoms at baseline experienced significant

95 ine antagonist onto the cortical surface the dyskinetic symptoms disappear.

96 ioning that might underlie the generation of dyskinetic symptoms in patients with PD who have receive

97 Some of the hereditary dyskinetic syndromes are characterized by paroxysmal ons

98 l-genetic spectrum of combined epileptic and dyskinetic syndromes.

99 pectively, in segments that were akinetic or dyskinetic under resting conditions (83% concordance wit

100 Considering dibenzazepines, 2 was not dyskinetic whereas 2a was dyskinetic.

101 6-hydroxydopamine lesions (6-OHDA) rendered dyskinetic with chronic L-DOPA treatment reveals a compl

102 phenyl-1,2,3,6-tetrahydropyridine (MPTP) and dyskinetic with levodopa.