ライフサイエンスコーパス: dystonic

1 The hands exhibit dystonic and athetoid posturing and fisting.

2 ) is characterized by attacks of involuntary dystonic and choreoathetoid movements, typically several

3 Given the improvement in dystonic and hemiballistic movements in these patients a

4 here were no significant differences between dystonics and normals in regional blood flow, blood volu

5 hindbrain structures will produce an overtly dystonic animal.

6 eveloped abnormal involuntary movements with dystonic-appearing, self-clasping of limbs, as early as

7 orward rate constant was decreased by 29% in dystonics, as compared with normals (p < 0.05).

8 ay K8644 induced stereotypic tottering mouse dystonic at concentrations significantly below those req

9 etal muscle was normal, appearance of severe dystonic ataxia correlated with postnatal degeneration o

10 Microdialysis of the striatum revealed dystonic attacks in tottering mice to be associated with

11 l removal of the cerebellum eliminated their dystonic attacks.

12 A) or quinolinic acid (QA) exaggerated their dystonic attacks.

13 sed facilitation to inhibition ratios in the dystonic brain.

14 Paroxysmal dystonic choreoathetosis (PDC) is characterized by attac

15 Paroxysmal dystonic choreoathetosis (PDC) is characterized by attac

16 ase gene on chromosome 4p; 2) the paroxysmal dystonic choreoathetosis gene at 2q34; 3) the dentatorub

17 orts of dystonia, chorea encephalopathy, and dystonic choreoathetosis occurring as sequelae of strept

18 ted with many different genetic and acquired dystonic disorders.

19 brief paroxysmal episodes in puberty, either dystonic/dyskinetic or "shivering" attacks, triggered by

20 axia, polyspike discharges, and intermittent dystonic episodes.

21 s showed no epileptiform activity during the dystonic events.

22 nical phenotype was novel, with 50% having a dystonic extrapyramidal movement disorder, and 70% a beh

23 These dystonic features are the quickest to respond to high fr

24 gestion of a stronger tendency for spread of dystonic features in patients with associated tremor.

25 No animals had dystonic features.

26 ensitive and specific feature distinguishing dystonic from psychogenic torticollis.

27 ing an asymptomatic motor task involving the dystonic hand and an unrelated asymptomatic task, senten

28 mutant mouse (lamb1t) exhibits intermittent dystonic hindlimb movements and postures when awake, and

29 in in cellular function, in either normal or dystonic individuals is not known.

30 cases lacking the GAG deletion (N = 17), in dystonic individuals with apparent homozygosity in the 9

31 Dystonic involuntary muscle spasms were specifically ass

32 the importance of this LCI pathology, murine dystonic-like movements are reduced significantly with a

33 on, and link abnormalities of these cells to dystonic-like movements in an overtly symptomatic animal

34 ical model of primary dystonia that exhibits dystonic-like twisting movements has stymied identificat

35 ain cholinergic and GABAergic neurons causes dystonic-like twisting movements that emerge during juve

36 The dystonic mice exhibit movement-induced, sustained abnorm

37 In vivo recordings from dystonic mice revealed abnormal high-frequency bursting

38 al. establish the first animal model with a dystonic motor phenotype and link torsinA hypofunction t

39 type and display vulnerability to developing dystonic movements after systemic or intrastriatal injec

40 acterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol.

41 triatum in two different animal models where dystonic movements are thought to originate from abnorma

42 A directly into the striatum ameliorated the dystonic movements but cerebellar microinjections of l-D

43 xplore the hypothesis that the expression of dystonic movements depends on influences from a motor ne

44 They suggest that expression of dystonic movements depends on influences from both basal

45 and a greater understanding of the causes of dystonic movements from the study of genetics, neurophys

46 rmal eye movements were temporally linked to dystonic movements in the limbs on the side opposite the

47 In basal conditions, no overt dystonic movements or postures or change in locomotor ac

48 s characterized by brief episodes of choreic/dystonic movements precipitated by sudden movement.

49 recurrent and brief attacks of choreiform or dystonic movements triggered or exacerbated by sudden vo

50 When dystonic movements were triggered by pharmacological sti

51 ity was mainly found in patients with phasic dystonic movements where it was suppressed after high fr

52 exhibiting rapid spinal nerve degeneration, dystonic movements, and severe ataxia.

53 R6/2 mouse reveal age-related impairments in dystonic movements, motor performance, grip strength, an

54 ay, central hypotonia, spastic quadriplegia, dystonic movements, rotary nystagmus, and impaired gaze

55 10 characterized by progressive ataxic gait, dystonic movements, spontaneus seizures, and death by de

56 s to enhance dopamine signalling reduced the dystonic movements, whereas administration of D1- or D2-

57 osing DYT1 gene mutation carriers to develop dystonic movements.

58 pamine, playing a role in the development of dystonic movements.

59 cal condition characterized by myoclonic and dystonic muscle contractions and the absence of other ne

60 ve afferents, such as aberrant feedback from dystonic muscles, may continue to potentiate brainstem c

61 Stimulated by the ego-dystonic nature of obsessive-compulsive disorder (OCD),

62 s, inherited metabolic diseases, and genetic dystonic or parkinsonian syndromes) and are, therefore,

63 system may play a key role in explaining ego-dystonic or self-destructive behaviour.

64 Dystonic patients had even less 11-30 Hz power and great

65 We report here that when focal hand dystonic patients performed finger-tapping tasks, functi

66 lar histopathological studies on brains from dystonic patients who have undergone DBS.

67 chniques over S1 for therapeutic purposes in dystonic patients.

68 Major reinnervation and/or change in the dystonic pattern occurred following 29% of the procedure

69 effect, producing viable adults with a novel dystonic phenotype.

70 splicing of 10% of Scn8amedJ pre-mRNA and a dystonic phenotype.

71 rked improvement, and 4 (0.03%) no effect on dystonic posture.

72 be a consequence of maintaining an abnormal dystonic posture.

73 variant SMS (n = 2, limited to 1 limb [with dystonic posture] or back), and progressive encephalomye

74 s of mice elicited reliable and reproducible dystonic postures of the trunk and limbs.

75 rence of early and late oral automatisms and dystonic posturing of an upper extremity was analysed se

76 d a distinctive adult-onset, frequent, brief dystonic seizure semiology that predominantly affected t

77 GI1-IgG-positive patients with faciobrachial-dystonic seizures (9 of 39, 31%).

78 We have termed these faciobrachial dystonic seizures (FBDS).

79 d immunotherapy to treat their faciobrachial dystonic seizures (P = 0.02).

80 s with limbic encephalitis and faciobrachial dystonic seizures associated with LGI1 antibodies.

81 In conclusion, faciobrachial dystonic seizures can be prospectively identified as a f

82 ient, but a longer duration of faciobrachial dystonic seizures correlated with a reduction of pallidu

83 he four cases with relapses of faciobrachial dystonic seizures during corticosteroid withdrawal.

84 Faciobrachial dystonic seizures have recently been reported as immunot

85 hly associated and distinctive faciobrachial dystonic seizures is very important.

86 veloped hyponatremia; none had faciobrachial dystonic seizures or malignancy.

87 nalities are striking and only faciobrachial dystonic seizures reliably differentiate these two condi

88 Faciobrachial dystonic seizures were controlled more effectively with

89 the first prospective study of faciobrachial dystonic seizures with serial assessments of seizure fre

90 s associated with cessation of faciobrachial dystonic seizures within 1 week in three and within 2 mo

91 at (ii) effective treatment of faciobrachial dystonic seizures would accelerate recovery and prevent

92 We hypothesized that (i) faciobrachial dystonic seizures would show a differential response to

93 ents with limbic encephalitis, faciobrachial dystonic seizures, Morvan's syndrome and neuromyotonia.

94 Faciobrachial dystonic seizures, possibly pathognomonic for the VGKCC

95 escribed epileptic syndrome of faciobrachial dystonic seizures.

96 nt disorder characterized by sudden onset of dystonic spasms and slow movements.

97 atric changes, viral prodrome, faciobrachial dystonic spells or facial dyskinesias, and mesial tempor

98 d environmental factors that can trigger the dystonic state.

99 Cross-correlograms from the dystonic subjects revealed a central peak with a median

100 Dystonic subjects showed bilateral abnormalities of perc

101 In experiments without vibratory stimuli, dystonic subjects showed normal movement of the tracking

102 l perception of motion, but not position, in dystonic subjects.

103 tudes in theta and beta bands correlate with dystonic symptom severity across patients.

104 Dystonic symptom severity significantly correlated with

105 coupling showed an inverse correlation with dystonic symptom severity.

106 sorder characterized by myoclonic jerks with dystonic symptoms and caused by mutations in paternally

107 ternal pallidum are robustly associated with dystonic symptoms in cervical dystonia and may be a usef

108 zepine, and trihexyphenidyl, which alleviate dystonic symptoms in patients.

109 served in patients with head tremor, whereas dystonic symptoms involving the arms were more frequentl

110 Dystonic symptoms involving the neck were more frequentl

111 latory connectivity and its association with dystonic symptoms provides further confirmation of cereb

112 present the neurons directly associated with dystonic symptoms, impaired release of neurotransmitters

113 splay an unusually large phenotypic range of dystonic symptoms.

114 retraining and stimulation for restoring the dystonic symptoms.

115 ficantly with either severity or duration of dystonic symptoms.

116 training may reverse sensory impairment and dystonic symptoms.

117 To date, at least 13 dystonic syndromes have been distinguished on a genetic

118 same time, the phenotypes of other forms of dystonic syndromes have been expanded or linked together

119 The dystonic syndromes include a large group of diseases tha

120 Patients with dystonic syndromes sometimes develop increasingly freque

121 ndscape with respect to the cause of various dystonic syndromes that is likely to make a direct impac

122 Two sisters had early-onset parkinsonism (dystonic toe curling, action tremor, masked face, bradyk

123 The pathophysiology of idiopathic dystonic torticollis is unclear and there is no simple t

124 corticoreticular and corticospinal drive in dystonic torticollis.

125 or due to Parkinson's disease, essential and dystonic tremor and tremor related to multiple sclerosis

126 Dystonic tremor is presumably under-reported, and we aim

127 Dystonic tremor is under-reported and this underscores t

128 ospective case note analysis did not suggest dystonic tremor or indeterminate tremor in any of them.

129 currently proposed clinical subdivision of 'dystonic tremor' and 'tremor associated with dystonia'.

130 been cases of indeterminate senile tremor or dystonic tremor.