ライフサイエンスコーパス: e-cigarette

1 below the limit of quantification to 239 mug/e-cigarette.

2 he safety of pure nicotine inhalation, i.e., E-cigarettes.

3 luding fruit-, candy-, and cocktail-flavored e-cigarettes.

4 n limited research on flavoring chemicals in e-cigarettes.

5 ct of flavoring compounds on the toxicity of e-cigarettes.

6 rette puffing topography device for use with e-cigarettes.

7 present in a convenience sample of flavored e-cigarettes.

8 potentially widespread exposure via flavored e-cigarettes.

9 , irrespective of their motivation for using e-cigarettes.

10 ation among Internet tobacco vendors selling e-cigarettes.

11 At baseline, 16 participants (2.3%) used e-cigarettes.

12 ical vulnerability to nicotine, tobacco, and e-cigarettes.

13 nisms governing the sale and distribution of e-cigarettes.

14 uncontrolled, experimental studies involving e-cigarettes.

15 es have already banned or strictly regulated e-cigarettes.

16 ajor stimulant in tobacco products including e-cigarettes.

17 otherwise healthy humans who habitually use e-cigarettes.

18 ers and 128 of 678 of those who had not used e-cigarettes (18.9%) progressed toward cigarette smoking

19 a primary 3D airway model acutely exposed to e-cigarette aerosol and cigarette (3R4F) smoke.

20 tifying and comparing the levels of selected e-cigarette aerosol components to those found in traditi

21 Two e-cigarette aerosol dilutions were tested for equivalent

22 gher nicotine delivery, an acute exposure to e-cigarette aerosol had a reduced impact on gene express

23 Components of e-cigarette aerosol have known pulmonary toxicity.

24 We performed validation using air and e-cigarette aerosol under multiple regimes.

25 ferentially expressed at the highest dose of e-cigarette aerosol using a looser threshold of pFDR < 0

26 Electronic cigarettes (e-cigarettes) aerosolize nicotine and produce a vapor th

27 ced by PG and GLY than have been reported in e-cigarette aerosols to date.

28 We hypothesized that nicotine and e-cigarettes affect myofibroblast differentiation, gel c

29 f the vendors complied with North Carolina's e-cigarette age-verification law.

30 Ethical concerns surround the use of e-cigarettes among minors and their potential to undermi

31 tudinal studies that assessed initial use of e-cigarettes and subsequent cigarette smoking.

32 nt difference in adverse event rates between e-cigarettes and the nicotine patch.

33 iven the rapid increase in the popularity of e-cigarettes and the paucity of associated longitudinal

34 xt words to capture concepts associated with e-cigarettes and traditional cigarettes in articles publ

35 ual users of both combustible cigarettes and e-cigarettes, and long-term users of both combustible ci

36 smoked traditional cigarettes are now using e-cigarettes, and these individuals may be at risk for s

37 As currently being used, e-cigarettes are associated with significantly less quit

38 Currently in the United States, e-cigarettes are exempt from regulation as drug-delivery

39 Although e-cigarettes are marketed as safer alternatives to tradi

40 This is coupled with a perception that e-cigarettes are safe and with unlimited advertising gea

41 Although e-cigarettes are widely sold online and by retailers, ne

42 E-cigarettes are widely used among smokers attempting to

43 DS), which include electronic cigarettes, or e-cigarettes, are growing in popularity, but their safet

44 f data concerning the safety and efficacy of e-cigarettes as a smoking cessation therapy, available e

45 placement therapy and electronic cigarettes (e-cigarettes), as long-term substitutes for cigarettes i

46 ents in Los Angeles, those who had ever used e-cigarettes at baseline compared with nonusers were mor

47 e of US adolescents and young adults, use of e-cigarettes at baseline was associated with progression

48 In conclusion, our data suggest that e-cigarette autofluorescence can be used as a marker of

49 ve recently turned to electronic cigarettes (e-cigarettes) because they have been marketed as a cheap

50 pes of flavored e-cigarettes sold by leading e-cigarette brands and flavors we deemed were appealing

51 We show that, within the tested e-cigarette brands, thermal decomposition of flavoring c

52 ette flavors from the top selling disposable e-cigarette brands.

53 s and 2.2 s) were similar with both types of e-cigarette, but mean puff volumes (52.2 mL and 83.0 mL)

54 okers during pregnancy as well as the use of e-cigarettes by e-cigarette-only users who think them sa

55 Studies have concluded that e-cigarettes can help reduce the number of cigarettes sm

56 dds of smoking cessation among smokers using e-cigarettes compared with smokers not using e-cigarette

57 cigarettes were 28% lower in those who used e-cigarettes compared with those who did not use e-cigar

58 broblasts with various doses of nicotine and e-cigarette condensate and determined myofibroblast diff

59 E-cigarette contents were fully discharged and the air s

60 The public health implications of e-cigarettes depend, in part, on whether e-cigarette use

61 hnique, we found that every 70 mL puff of an e-cigarette deposited 0.019% e-liquid (v/v) in a control

62 autofluorescence can be used as a marker of e-cigarette deposition.

63 The role of nicotine and e-cigarette derived nicotine on cellular functions inclu

64 Flavoring chemicals in e-cigarettes: diacetyl, 2,3-pentanedione, and acetoin in

65 Use of e-cigarettes does not discourage, and may encourage, con

66 rted by 502 (24.0%), of whom 201 (9.6%) used e-cigarettes during the last 30 days (current users).

67 rmal decomposition of the main components of e-cigarette e-liquids (propylene glycol and glycerol), w

68 Due to the novelty of e-cigarettes (e-cigs) and e-cigarette liquids (e-liquids

69 To date, studies of e-cigarette emissions have mainly focused on chromatogra

70 All e-cigarette emissions tested contained at least one alde

71 tant for standardising testing protocols for e-cigarette emissions.

72 Electronic cigarettes (e-cigarettes) entered the US market in 2007 and, with li

73 Use of e-cigarettes, especially among the young, is increasing

74 obacco product was more frequent in baseline e-cigarette ever users (n = 222) than never users (n = 2

75 , apoptosis, and hypoxia were identified for e-cigarette exposures, albeit with a lower confidence sc

76 There are > 7,000 e-cigarette flavors currently marketed.

77 We selected 24 e-cigarette flavors from the top selling disposable e-ci

78 E-cigarette fluids (with and without nicotine) trigger m

79 HGFs were treated with e-cigarette fluids containing nicotine (final concentrat

80 Smokers increasingly use e-cigarettes for many reasons, including attempts to qui

81 available data on the efficacy and safety of e-cigarettes for smoking cessation and to consider issue

82 Minors successfully received deliveries of e-cigarettes from 76.5% of purchase attempts, with no at

83 Minors are easily able to purchase e-cigarettes from the Internet because of an absence of

84 Electronic cigarettes (e-cigarettes) generate an aerosol vapor (e-vapor) though

85 Electronic cigarettes (e-cigarettes) have gained unprecedented popularity, but

86 ring this time with nicotine, via tobacco or e-cigarettes, have unique consequences on adolescent dev

87 E-cigarettes heat and aerosolize the solvents propylene

88 ale of e-cigarettes to minors and the use of e-cigarettes in public places, infants, children, and ad

89 Regulations on e-cigarettes in the U.S. do not provide guidelines on th

90 stantial evolution of electronic cigarettes (e-cigarettes) in the past 5-6 years, how these devices a

91 We found that both nicotine and e-cigarette inhibit myofibroblast differentiation as sho

92 Nicotine and e-cigarette inhibited OXPHOS complex III accompanied by

93 ly differ among studies of all smokers using e-cigarettes (irrespective of interest in quitting cigar

94 ols (i.e., vapor plus particulate phases) of e-cigarettes is needed in order to better inform basic r

95 posure to nicotine in electronic cigarettes (e-cigarettes) is becoming increasingly common among adol

96 E-cigarettes likely represent a lower risk to health tha

97 to the novelty of e-cigarettes (e-cigs) and e-cigarette liquids (e-liquids), research on their chemo

98 is to further investigate the effects of the e-cigarette liquids (with and without nicotine) on the s

99 How flavoring compounds in e-cigarette liquids affect the chemical composition and

100 rovide guidelines on the chemical content of e-cigarette liquids.

101 What effect e-cigarettes may have on pediatric health remains unknow

102 f tobacco cigarettes, electronic cigarettes (e-cigarettes) may facilitate smoking cessation.

103 Electronic cigarettes (e-cigarettes) may help smokers reduce the use of traditi

104 therefore, the results obtained from a given e-cigarette might not read across to other products.

105 Self-report of baseline e-cigarette nicotine concentration of none (0 mg/mL), lo

106 garettes compared with those who did not use e-cigarettes (odds ratio [OR] 0.72, 95% CI 0.57-0.91).

107 E-Cigarettes offer a very wide variety of flavors, which

108 unities, and online stores where people sell e-cigarettes on commission, is increasing rapidly.

109 needed to determine the long-term effects of e-cigarettes on respiratory health.

110 Meanwhile, the presence of e-cigarettes on the Internet, including in Web searches,

111 te at which minors can successfully purchase e-cigarettes on the Internet.

112 The e-cigarette-only and NRT-only users had significantly lo

113 Former smokers with long-term e-cigarette-only or NRT-only use may obtain roughly simi

114 former smokers with long-term (>/=6 months) e-cigarette-only or NRT-only use, and long-term dual com

115 Long-term NRT-only and e-cigarette-only use, but not dual use of NRTs or e-ciga

116 The e-cigarette-only users had significantly lower NNAL leve

117 gnancy as well as the use of e-cigarettes by e-cigarette-only users who think them safe or by those s

118 se, and long-term dual combustible cigarette-e-cigarette or combustible cigarette-NRT users (n = 36 t

119 oking initiation associated with ever use of e-cigarettes or past 30-day cigarette smoking associated

120 e cigarette-only, dual combustible cigarette-e-cigarette, or dual combustible cigarette-NRT users.

121 ises concerns about both the combined use of e-cigarettes plus conventional cigarettes by smokers dur

122 g minors aged 14 to 17 years made supervised e-cigarette purchase attempts from 98 Internet e-cigaret

123 growing popularity of electronic cigarettes (e-cigarettes) raises concerns about the possibility of a

124 Strong e-cigarette regulation could potentially curb use among

125 ested at concentrations up to 64 and 529 mug/e-cigarette, respectively.

126 nd enforce rigorous age verification for all e-cigarette sales as with the federal PACT (Prevent All

127 able efficacy claims, and safety concerns of e-cigarettes so that they may counsel patients against u

128 We selected 51 types of flavored e-cigarettes sold by leading e-cigarette brands and flav

129 ns to limit sales and decrease the appeal of e-cigarettes to adolescents and young adults.

130 s demonstrate the potential for human use of e-cigarettes to facilitate covert use of a range of psyc

131 sdictions have laws that prevent the sale of e-cigarettes to minors and the use of e-cigarettes in pu

132 able "cig-a-like" or larger button-activated e-cigarettes, to use ad-libitum in two sessions.

133 Prior reports on e-cigarette toxin production have emphasized temperature

134 ts were asked about their use of cigarettes, e-cigarettes, traditional cigars, cigarillos, filtered c

135 These data provide robust validation of e-cigarette-type technology as a model for inhaled deliv

136 th professionals to be aware of the risks of e-cigarette usage during pregnancy, particularly as it p

137 addicted to nicotine to not be able to quit e-cigarette usage during pregnancy.

138 RATIONALE: Rates of adolescent electronic (e-) cigarette use are increasing, but there has been lit

139 of e-cigarettes depend, in part, on whether e-cigarette use affects the risk of cigarette smoking.

140 revention has reported a trend of increasing e-cigarette use among teens, with use rates doubling fro

141 We aimed to assess the association between e-cigarette use and cigarette smoking cessation among ad

142 the independent association between baseline e-cigarette use and cigarette smoking, controlling for s

143 ed by nicotine, making it highly likely that e-cigarette use during pregnancy will have the same harm

144 However, the efficacy and safety of e-cigarette use for this purpose remain poorly understoo

145 In the past 5 years, e-cigarette use has been increasing rapidly, particularl

146 garettes only, former smokers with long-term e-cigarette use only, former smokers with long-term nico

147 Current e-cigarette use was also associated with lower 30-day (O

148 Current e-cigarette use was also negatively associated with 30-d

149 In this study, habitual e-cigarette use was associated with a shift in cardiac a

150 Baseline e-cigarette use was associated with greater likelihood o

151 e-Cigarette use was associated with greater risk for sub

152 Among cigarette experimenters (1 puff), ever e-cigarette use was associated with higher odds of ever

153 the primary fully adjusted models, baseline e-cigarette use was independently associated with progre

154 smokers of cigarettes (100 cigarettes), ever e-cigarette use was negatively associated with 30-day (O

155 oduct-specific analyses showed that baseline e-cigarette use was positively associated with combustib

156 Current e-cigarette use was positively associated with ever smok

157 Ever e-cigarette use was reported by 502 (24.0%), of whom 201

158 To investigate the associations of e-cigarette use with chronic bronchitis symptoms and whe

159 Association of e-cigarette use with quitting did not significantly diff

160 no statistically significant associations of e-cigarette use with wheeze after adjustment for cigaret

161 equency of combustible cigarette smoking and e-cigarette use within the past 30 days (0 days [none],

162 ookah use, ever e-cigarette use, and current e-cigarette use) among New Jersey high school students,

163 erification of abstinence, and definition of e-cigarette use) were also not associated with the overa

164 om 38.1% (current hookah use) to 58.3% (ever e-cigarette use), indicating substantial false-negative

165 s (ever hookah use, current hookah use, ever e-cigarette use, and current e-cigarette use) among New

166 gn, population, definition and prevalence of e-cigarette use, comparison group (if applicable), cigar

167 ilable evidence on the risks and benefits of e-cigarette use, large, randomized, controlled trials ar

168 osure, increasingly occurring as a result of e-cigarette use, may induce epigenetic changes that sens

169 igarette smoking associated with past 30-day e-cigarette use.

170 esearch indicates that electronic cigarette (e-cigarette) use (vaping) among adolescents is associate

171 Electronic cigarette (e-cigarette) use has gained recent widespread popularity

172 Electronic cigarettes (e-cigarettes) use has increased globally and could poten

173 9 self-identified non-tobacco cigarette, non-e-cigarette user control participants.

174 Over the 1-year follow-up, 11 of 16 e-cigarette users and 128 of 678 of those who had not us

175 study including 23 self-identified habitual e-cigarette users and 19 self-identified non-tobacco cig

176 ollow-up were 21.5% for baseline past 30-day e-cigarette users and 4.6% for baseline non-past 30-day

177 king initiation were 30.4% for baseline ever e-cigarette users and 7.9% for baseline never e-cigarett

178 oss-sectional case-control study of habitual e-cigarette users and nonuser control individuals from 2

179 r past 30-day e-cigarette vs non-past 30-day e-cigarette users at baseline.

180 Otherwise healthy habitual e-cigarette users between the ages of 21 and 45 years me

181 to oxidation, was significantly increased in e-cigarette users compared with nonuser control individu

182 P = .05) were significantly increased in the e-cigarette users compared with nonuser control particip

183 component was significantly decreased in the e-cigarette users compared with nonuser control particip

184 Adolescent e-cigarette users had increased rates of chronic bronchi

185 igarette-NRT, and dual combustible cigarette-e-cigarette users had largely similar levels of TSNA and

186 ever, risk of bronchitic symptoms among past e-cigarette users remained elevated after adjustment for

187 eeting these inclusion criteria who were not e-cigarette users were eligible to be enrolled as contro

188 s 3.62 (95% CI, 2.42-5.41) for ever vs never e-cigarette users, and the pooled odds ratio for past 30

189 0-day cigarette smokers who were past 30-day e-cigarette users, past 30-day cigarette smoking at foll

190 -cigarette users and 7.9% for baseline never e-cigarette users.

191 users and 4.6% for baseline non-past 30-day e-cigarette users.

192 rmaldehyde concentrations of 626 mug/m(3) in e-cigarette vapor exceed the ACGIH maximum concentration

193 emissions are expected to be ubiquitous when e-cigarette vapor is present.

194 ions of aldehydes and flavoring chemicals in e-cigarette vapor under typical usage conditions.

195 most prevalent of the flavoring chemicals in e-cigarette vapor, being found in more than 60% of sampl

196 demonstrated formation of toxic aldehydes in e-cigarette vapors during vaping.

197 ect the chemical composition and toxicity of e-cigarette vapors is practically unknown.

198 tion as a pathway for aldehyde generation in e-cigarette vapors.

199 fects to primary users and people exposed to e-cigarette vapors.

200 cigarette purchase attempts from 98 Internet e-cigarette vendors.

201 f age-verification measures used by Internet e-cigarette vendors.

202 was 4.28 (95% CI, 2.52-7.27) for past 30-day e-cigarette vs non-past 30-day e-cigarette users at base

203 Use of e-cigarettes was associated with higher odds of ever or

204 rs with conventional cigarettes, ever use of e-cigarettes was associated with lower 30-day (OR = 0.24

205 d multiple tobacco products; cigarettes plus e-cigarettes was the most common combination.

206 e-cigarettes compared with smokers not using e-cigarettes were assessed using a random effects meta-a

207 E-cigarettes were connected to a pump drawing air for tw

208 current cigarette smokers who had ever used e-cigarettes were more likely to intend to quit smoking

209 Associations of self-reported use of e-cigarettes with chronic bronchitic symptoms (chronic c

210 arette-only use, but not dual use of NRTs or e-cigarettes with combustible cigarettes, is associated

211 ldehydes produced by three popular brands of e-cigarettes with flavored and unflavored e-liquids.

212 Use of e-cigarettes with high (vs no) nicotine concentration wa

213 udy provide preliminary evidence that use of e-cigarettes with higher nicotine concentrations by yout

214 To evaluate whether use of e-cigarettes with higher nicotine concentrations is asso

215 w-up) of 2015 to students who reported using e-cigarettes within the past 30 days and the nicotine co

216 t self-report of whether he or she ever used e-cigarettes (yes or no) at baseline.