ライフサイエンスコーパス: early childhood

1 that this phenomenon has already matured by early childhood.

2 lower cognitive test scores measured during early childhood.

3 th increased risk of harm to the fetus or in early childhood.

4 s a rare and aggressive stem cell disease of early childhood.

5 to a broad array of allergenic molecules in early childhood.

6 ith adiposity gain and risk of overweight in early childhood.

7 inia enterocolitica causes acute diarrhea in early childhood.

8 east milk and anthropometric measurements in early childhood.

9 ese foods has not been well characterized in early childhood.

10 n and acute respiratory distress syndrome in early childhood.

11 ted cardiomyopathy in utero, at birth, or in early childhood.

12 t circumference, and fat mass in boys during early childhood.

13 infection around the time of birth or during early childhood.

14 f gestation) birth on eating difficulties in early childhood.

15 d that this infrastructure is present during early childhood.

16 ncy was not associated with cognition during early childhood.

17 drome associated with severe lung disease in early childhood.

18 and epilepsy, ultimately leading to death in early childhood.

19 lysis of IgE reactivity to PR-10 proteins in early childhood.

20 urodevelopmental impairment and four died in early childhood.

21 ng resolution of differential methylation by early childhood.

22 s a major public health issue, especially in early childhood.

23 though both were diagnosed as having cPAN in early childhood.

24 t in a life-threatening disease phenotype in early childhood.

25 ese compared with lean children beginning in early childhood.

26 , a severe hereditary blindness occurring in early childhood.

27 equate and harmful input when experienced in early childhood.

28 rdiac, or general development of children in early childhood.

29 obiology of depressive disorders starting in early childhood.

30 eviations from the expectable environment in early childhood.

31 erized by multisystem morbidity and death in early childhood.

32 sity was associated with offspring growth in early childhood.

33 ve neurodegenerative disorder that occurs in early childhood.

34 uperior persistence of antibody responses in early childhood.

35 ersistence of methylation differences beyond early childhood.

36 ions were not explained by protein intake in early childhood.

37 on the natural history of peanut allergy in early childhood.

38 ory lesions at acral locations presenting in early childhood.

39 penia with frequent infections, and death in early childhood.

40 a risk and parasite density were greatest in early childhood.

41 me is not limited to survivors' diagnoses in early childhood.

42 dren ranked in the lowest tertile (28.6%) in early childhood.

43 d subsequent asthma through sensitization in early childhood.

44 not differ across census regions, except in early childhood.

45 evated plasma insulin levels at birth and in early childhood.

46 nic lung disease that commonly originates in early childhood.

47 older children through eczema and FAS during early childhood.

48 and the illusion is known to be acquired in early childhood.

49 may improve social-emotional development in early childhood.

50 k factors for linear growth faltering during early childhood.

51 Otitis media (OM) is common in early childhood.

52 to PAHs has been associated with obesity in early childhood.

53 nation, pertussis was a universal disease of early childhood.

54 All patients had developed nyctalopia from early childhood.

55 ata on the zinc status of vegetarians during early childhood.

56 The onset of CORD occurred in early childhood.

57 racterized by neurodegeneration and death in early childhood.

58 mothers beyond the perinatal period and into early childhood.

59 n intact epithelial/epidermal barrier during early childhood.

60 is the most common cause of food allergy in early childhood.

61 th egg allergy, which had been present since early childhood.

62 stigate the stability of associations across early childhood.

63 of morbidity after traumatic brain injury in early childhood.

64 most severe form of inherited retinopathy in early childhood.

65 r; 1.5%) and late (<3 yr; 4.1%) onset during early childhood.

66 odds for late respiratory morbidities during early childhood.

67 cal signs of late respiratory disease during early childhood.

68 YKL-40 levels) are associated with asthma in early childhood.

69 on showed no association with asthma through early childhood (0-6 years) when analyzed as any sensiti

70 g risk for excess weight gain in infancy and early childhood?" (2) "What is known regarding intervent

71 seroclearance occurred predominantly in the early childhood, 20-24 and 35-39 year age groups.

72 n with CMT1A progressed consistently through early childhood (3-10 years) and adolescence (11-20 year

73 heeze, asthma, and allergen sensitization in early childhood (3-5 years of age, n = 1419) and midchil

74 We observed null associations for boys and early-childhood adiposity measures.

75 e of healthy adults (n=30) with a history of early childhood adversity, and a control group (n=30) wi

76 splasia (BPD) and respiratory disease during early childhood after preterm birth, we performed a pros

77 nt a role after transplant as it once did in early childhood, allowing a more complete restoration of

78 inst the development of eczema and wheeze in early childhood, although there was evidence in subgroup

79 ult acute myeloid leukemia (AML) but rare in early childhood AML.

80 ifferent age groups including fetus, infant, early childhood and adult.

81 associations between H. pylori infection in early childhood and atopy and reported allergic disorder

82 =3 mo may be associated with rapid growth in early childhood and body composition in young adulthood.

83 ences in the communication of the science of early childhood and brain development and our recommenda

84 Cardiomyocyte exchange is highest in early childhood and decreases gradually throughout life

85 products will encourage rapid weight gain in early childhood and exacerbate risk factors for chronic

86 y and its associated anemia in pregnancy and early childhood and in characterizing states of iron rep

87 an herpesvirus 8 (HHV-8) infection occurs in early childhood and is associated with human immunodefic

88 Food fussiness (FF) is common in early childhood and is often associated with the rejecti

89 besity-associated AT dysfunction develops in early childhood and is related to insulin resistance.

90 tively associated with children's BMI during early childhood and particularly with higher fat mass.

91 od pressure among preterm children emerge in early childhood and that neighborhood SES accounts for a

92 he frequency of physical aggression peaks in early childhood and then decreases until old age.

93 Paraoxonase 1 gene (PON1) that persisted in early childhood and was attenuated in mid-childhood bloo

94 environmental exposures during pregnancy and early childhood and whether BAFF levels are associated w

95 is document is intended to meet the needs of early-childhood and school settings as well as providers

96 n with the seasonal influenza vaccine during early childhood, and identify potential molecular correl

97 ediatric malignancy that typically arises in early childhood, and is derived from the developing symp

98 Limiting overnutrition during pregnancy, early childhood, and puberty would avoid not only obesit

99 during pregnancy, receiving vaccinations in early childhood, and starting day care between 1.5 and 3

100 ioural and emotional problems often start in early childhood, and this might be particularly importan

101 structure and function from infancy through early childhood, and this significantly influences cogni

102 ed to different temperatures in utero and in early childhood, and we estimate flexible regression mod

103 ominated diphenyl ethers and its relation to early childhood anthropometric measurements.

104 Early childhood appears to serve as an approximate time

105 birth and in infancy ( approximately 6 mo), early childhood ( approximately 3 y), and midchildhood (

106 financial losses due to growth faltering in early childhood are not available.

107 rain structure and intrinsic connectivity in early childhood are predictive of 6 year outcomes in num

108 nfections, enteropathy and undernutrition in early childhood are preventable risk factors for child d

109 fuel for science-informed innovation in the early childhood arena.

110 he potential for relatively common fetal and early childhood arsenic exposures, our finding that pren

111 Our results further underscore early childhood as an important developmental period for

112 fined condition that manifests in infancy or early childhood as deficits in communication skills and

113 These findings suggest that poverty in early childhood, as assessed by at least one measure, ma

114 d the hypothesis that poverty experienced in early childhood, as measured by income-to-needs ratio, h

115 gestation were significantly associated with early childhood asthma development.

116 ociations between infant antipyretic use and early childhood asthma.

117 Pathological early childhood attachments have far-reaching consequenc

118 Most children vaccinated during early childhood available for sampling maintained seropo

119 te the fact that the symptoms of AS occur in early childhood, behavioral characterization of AS mouse

120 In embryonic life and after early childhood, beta cell replication is barely detecta

121 dy mass index (BMI) peak characteristics and early childhood BMI are emerging markers of future obesi

122 infancy BMI peak characteristics and higher early childhood BMI.

123 We examined prenatal and early-childhood BPA exposures in relation to childhood m

124 ncreased BMI at 2-5 years of age, but higher early-childhood BPA exposures were associated with accel

125 Prenatal and early-childhood BPA exposures were not associated with i

126 ased asthma (OR, 1.26; 95% CI, 1.02-1.58) in early childhood but not midchildhood.

127 e surviving not only through their Fontan in early childhood, but also into adolescence and young adu

128 birth length, and arterial wall thickness in early childhood, but not adiposity or growth trajectory

129 Celiac disease is often diagnosed in early childhood, but some patients receive a diagnosis l

130 gg allergy (HEA) as a common food allergy in early childhood, but the true incidence is unclear becau

131 shared environmental factors was greatest in early childhood, but these effects remained present unti

132 nked to decreased risk of atopic diseases in early childhood, but whether such relations persist unti

133 c work suggests that institutionalisation in early childhood can incur developmental damage across di

134 Visual impairment (VI) in early childhood can significantly impair development.

135 individuals with LQTS, especially those with early childhood cardiac arrest, extreme QT prolongation,

136 Early childhood caries (ECC) is the most common infectio

137 nt and outcome prediction, as they relate to early childhood caries (ECC)-a common complex disease wi

138 merica suffer from a higher degree of severe early childhood caries (S-ECC) than the general populati

139 s is often detected with Candida albicans in early childhood caries.

140 plaque biofilms from children affected with early childhood caries.

141 plaque-biofilms from children affected with early-childhood caries, a prevalent and costly oral dise

142 aggressive hematopoietic disorder of infancy/early childhood caused by excessive proliferation of cel

143 ive neurodegenerative disorder presenting in early childhood, caused by an inherited deficiency of th

144 ex structure and function, such that without early childhood cochlear-implant, profoundly deaf childr

145 uential allergy and respiratory disorders in early childhood contributes enormously to the burden of

146 Rapid-growth patterns in early childhood could be a mediating link between infant

147 at a high intake of dietary soluble fiber in early childhood decreases the risk of type 1 diabetes (T

148 is study demonstrates an association between early childhood depression and the trajectory of cortica

149 hese findings underscore the significance of early childhood depression on alterations in neural deve

150 increase in insulin secretion that occurs in early childhood despite increased glucose.

151 Despite progress, early childhood development (ECD) remains a neglected is

152 of this Series) and increasing commitment to early childhood development (Paper 1 of this Series), sc

153 Services and interventions to support early childhood development are essential to realising t

154 nition of the damaging effects of poverty on early childhood development has fueled an interest in in

155 ough the evidence base for the importance of early childhood development has grown, the research is d

156 The present paper uses Early Childhood Development Index (ECDI) data collected

157 provide a comprehensive updated analysis of early childhood development interventions across the fiv

158 Early childhood development programmes vary in coordinat

159 years of age, thereby supporting its role in early childhood development, and policy change toward MM

160 s paper, the first in a three part Series on early childhood development, we examine recent scientifi

161 mplement interventions, at scale, to promote early childhood development.

162 cientific progress and global commitments to early childhood development.

163 d apply this rationale to other phenomena in early childhood development.

164 esence of specific sensitization patterns in early childhood differentially associated with developme

165 places recent neurodevelopmental research on early childhood disruptive behavior within the historica

166 in very early life--ie, in utero and during early childhood--drive the development of clinically app

167 include parent and family-focused programs, early childhood education, school-based programs, therap

168 t measure modification (EMM) p-value = 0.30, early-childhood EMM p-value = 0.05], but sex-specific as

169 nding of long-term metabolic consequences of early childhood enteric infections.

170 or additional resources aimed at remediating early childhood environments.

171 upt lifelong language loss following a brief early childhood epilepsy with continuous spike-waves in

172 Adversity in early childhood exerts an enduring impact on mental and

173 Also, early childhood exposure to TRAP was associated with dev

174 lems in adulthood may be rooted partially in early childhood exposure to unpredictable events and env

175 structure, and unmeasured characteristics of early childhood factors.

176 th correlated early-life exposures including early childhood farm animal contact and raw milk consump

177 t that symptom onset typically occurs during early childhood, few studies have yet examined the possi

178 ed models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ra

179 Our study shows that, by early childhood, frontotemporal (long segment) and front

180 A growing literature has linked early childhood growth to later-life cognition and schoo

181 pregnancy BMI, GWG, and percentile change in early childhood growth with BMI in daughters at midlife.

182 Our results indicate that the annual cost of early-childhood growth faltering is substantial.

183 e to the farming environment in utero and in early childhood had little or no association with asthma

184 Significance statement: Math anxiety during early childhood has adverse long-term consequences for a

185 Increased growth in early childhood has been suggested to increase the risk

186 s on obesity, growth patterns in infancy and early childhood have gained much attention.

187 els during the initiation phase of asthma in early childhood have not been reported.

188 For example, a systematic review of early childhood home visitation programs found a 38.9% r

189 improved persistence of immunogenicity into early childhood, however data are scarce.

190 e most important viral cause of pneumonia in early childhood (ie, younger than 2 years), responsible

191 rences in blood pressure trajectories across early childhood in a sample of African-American and Euro

192 with greater increases in weight and BMI in early childhood in this large cohort of United Kingdom c

193 study on incident physician-diagnosed AD in early childhood including 451 cases and 451 controls.

194 Respiratory viral infection in early childhood, including that from respiratory syncyti

195 During early childhood, individuals with high sensitivity to ea

196 Hygiene and other early childhood influences impact the subsequent functio

197 extends evidence of LOC specialization from early childhood into infancy and earlier than developmen

198 Faster weight growth in early childhood is associated with asthma and bronchial

199 25(OH)D deficiency in early childhood is associated with increased risk for pe

200 he first 2 years of life; however, growth in early childhood is challenging to characterize because g

201 Here, we show that emotion understanding in early childhood is more sophisticated than previously be

202 r hepatitis A vaccination during infancy and early childhood is unclear.

203 Because asthma often begins in early childhood, it is incumbent on us to continue to ad

204 o determine whether maternal, postnatal, and early childhood lead exposure can alter the differential

205 Our findings provide evidence that early childhood lead exposure results in sex-dependent a

206 icits.SIGNIFICANCE STATEMENT Hearing loss in early childhood leads to impairments in auditory percept

207 omotor developmental delays recognized since early childhood, learning disabilities and short stature

208 The causes of early childhood linear growth faltering (known as stunti

209 The effect of fetal and early childhood living conditions on adult health has lo

210 We evaluated data from the Early Childhood Longitudinal Study, Kindergarten Class o

211 ho were born in 2001 and participated in the Early Childhood Longitudinal Study-Birth Cohort.

212 tates by using the nationally representative Early Childhood Longitudinal Survey Birth Cohort (ECLS-B

213 ession of exercise-induced cardiac arrest in early childhood (</=3 years of age) and required aggress

214 Early childhood malnutrition affects 113 million childre

215 Early childhood malnutrition entails long-lasting epigen

216 Our aim was to identify the early childhood manifestations of this liability in a UK

217 findings demonstrate a significant effect of early childhood maternal support on hippocampal volume g

218 to examine whether sleep programs targeting early childhood may avert the onset of later adverse out

219 tronger evidence that gains in income during early childhood may promote healthy weight outcomes amon

220 l and central adiposity in 1,006 children in early childhood (median, 3.2 years) and 876 in mid-child

221 cination in pregnancy increases the risk for early childhood morbidity in offspring.

222 We detected no increased risk for early childhood morbidity.

223 content in blood collected at birth (n=306), early childhood (n=68; 2.9 to 4.9 y), and midchildhood (

224 trategies such as for treatment of inherited early childhood neurodegenerative diseases.

225 ncentrations were negatively associated with early childhood neurodevelopment scores in our study.

226 of ANS on rates of neonatal morbidities and early childhood neurodevelopmental outcomes of extremely

227 es of survival among these infants relate to early childhood neurodevelopmental outcomes.

228 ledge regarding the prevention of infant and early childhood obesity and to identify research gaps an

229 ears is associated with an increased risk of early childhood obesity.

230 mia, and optic atrophy (PEHO) syndrome is an early childhood onset, severe autosomal recessive enceph

231 Early childhood-onset wheezing that persists into adoles

232 l in nature and should be reclassified as an early-childhood-onset neurodevelopmental condition in DS

233 Such a roadmap is particularly relevant for early-childhood-onset neurodevelopmental conditions, whi

234 Cluster 3 (9.7%) female-early-childhood-onset-atopic-wheeze-with-impaired-lung-f

235 Cluster 2 (24.2%) early-childhood-onset-wheeze-with-intermediate-lung-func

236 During infancy and early childhood, ophthalmoscopic examination should be p

237 ast-feeding does not affect sensitization in early childhood or associated diseases at 7 years of age

238 dividual to individual; they can be fatal in early childhood, or relatively benign into adulthood.

239 tudents in grades K-3 and 4-12 completed the Early Childhood Oral Health Impact Scale (ECOHIS) and Fa

240 piratory tract infections during infancy and early childhood, particularly those occurring against a

241 Equitable early childhood policies and programmes are crucial for

242 Moreover, chemoprevention during early childhood prevented the development of dysfunction

243 t major developmental stages (prenatal time, early childhood, puberty time and adulthood).

244 reports on atopic diseases and microbiota in early childhood remain contradictory, and both decreased

245 ar mechanisms underlying vaccine immunity in early childhood remain poorly understood.

246 Early childhood represents a dynamic period for the inte

247 Early childhood represents a pivotal period amenable to

248 mosome gene FIGF (c.352 G>A) associated with early childhood respiratory deficiency.

249 ovided contradictory evidence on the role of early childhood respiratory infections in the developmen

250 Studies of early-childhood samples are needed to test whether appet

251 ool age and early adolescence and suggest an early childhood sensitive period for these effects.

252 Individuals with music training in early childhood show enhanced processing of musical soun

253 Callous-unemotional behaviors in early childhood signal higher risk for trajectories of a

254 As many as one-third of the children who had early childhood sleep terrors developed sleepwalking lat

255 nd supporting the relative importance of the early childhood social environment.

256 This article looks at both nutrition and early childhood stimulation interventions as part of an

257 mortality worldwide, continued high rates of early childhood stunting have put the global applicabili

258 t glimpses into the neuroanatomical bases of early childhood stuttering, and possible white matter de

259 pment of these lung function measures during early childhood, suggesting a window of opportunity for

260 biological constraints on preliteracy during early childhood, suggesting that neural processing of co

261 However, the long-term effects of early childhood TBI on functioning across settings remai

262 eas CMT2A appeared to progress faster during early childhood than adolescence (mean difference, 10.0;

263 r were not more likely to be hospitalized in early childhood than unexposed children (hospitalization

264 r were not more likely to be hospitalized in early childhood than unexposed children (hospitalization

265 lter the development of behavior problems in early childhood that can presage later mental illness.

266 Although typically identified in early childhood, the social communication symptoms and a

267 first years of life are highly unstable, by early childhood these trajectories stabilize and are pre

268 In early childhood, these levels were 11.2 microIU/mL (95%

269 e track the development of this ability from early childhood through adolescence and adulthood.

270 n or persistence of wheezing and asthma from early childhood through adulthood.

271 ales exhibiting increasing heritability from early childhood through young adulthood and females exhi

272 valences of nut sensitizations decrease from early childhood to adolescence.

273 the contribution of nonvertical exposures in early childhood to HCV prevalence among children at risk

274 and cysts (LCC), presenting at any age from early childhood to late adulthood.

275 g practices on changes in dental caries from early childhood to young adulthood.

276 to complex intention-based reciprocity from early childhood to young adulthood.

277 The impact of early childhood traffic-related air pollution (TRAP) exp

278 tudies to understand the association between early childhood TRAP exposure, and subsequent asthma, al

279 Rate ratios of hospitalization in early childhood until 5 years of age.

280 llergic rhinitis to birch pollen (ARbp) from early childhood up to age 16 years.

281 le for permanent growth deficits acquired in early childhood, vaccine failure, and loss of human pote

282 2 time points: at birth (cord blood) and in early childhood (venous blood).

283 first transition into income poverty during early childhood was associated with an increase in the r

284 ty of MMc to predict malaria outcomes during early childhood was evaluated in longitudinal models.

285 PFNA) concentrations in children assessed in early childhood were 5.6 (4.1-7.7), 24.8 (18.4-33.9), 2.

286 (adjusted HR = 2.11, 95% CI: 1.48, 3.00) in early childhood were strong predictors of asthma inciden

287 Although early childhood wheeze is common, persistent asthma is l

288 Early childhood wheezing is common, but predicting who w

289 psychological distress during pregnancy with early childhood wheezing.

290 t its effect on the brain during a period in early childhood when anxiety-related traits begin to be

291 Symptoms of ASD typically occur during early childhood, whereas most symptoms characteristic of

292 ic inflammatory disease and vasculitis since early childhood, which were refractory to classical trea

293 The three patients presented from early childhood with combined immunodeficiency and sever

294 d secondary generalized seizures starting in early childhood with developmental regression, did not i

295 ing principles of adaptation to adversity in early childhood with molecular, cellular, and whole orga

296 es FF and liking for vegetables and fruit in early childhood with the use of a twin design.

297 utcomes and neurodevelopmental impairment in early childhood, with a resultant secular trend away fro

298 etting improved antibody persistence through early childhood without compromising antibody responses

299 tal exposures during the prenatal period and early childhood years increase the risk of asthma.

300 eed to be continued or maintained during the early childhood years.