ライフサイエンスコーパス: early development

1 n overlapping function that is essential for early development.

2 oogenesis, cleavage-stage embryogenesis and early development.

3 ne enhancers during the phylotypic period of early development.

4 s that are established stochastically during early development.

5 normal neurophysiology, particularly during early development.

6 synaptic proteins and those expressed during early development.

7 potent states is important for understanding early development.

8 gulates muscle integrity and function during early development.

9 e effects of environmental pollutants during early development.

10 amily of formins, plays an important role in early development.

11 on of in-group members seems to be rooted in early development.

12 hromosome inactivation is established during early development.

13 fully innervate the lateral rectus muscle in early development.

14 ncrease of oligodendrocyte precursors during early development.

15 he spindle also scales with cell size during early development.

16 t1 and Tet2 during cell state transitions of early development.

17 ic components of breast milk that may affect early development.

18 nly rescued when Ube3a was reinstated during early development.

19 red for activation of Cdx2 expression during early development.

20 resent plausible intervention targets during early development.

21 ly transcripts synthesized and stored during early development.

22 se embryonic stem cells and are required for early development.

23 f higher-order chromatin architecture during early development.

24 nvolved in transcriptional elongation during early development.

25 -dependent adhesion during wound healing and early development.

26 patterns of signaling and gene expression in early development.

27 or noninvasive measurement of metabolites in early development.

28 enriched for differential expression during early development.

29 atheter mitral valve replacement is still in early development.

30 rent difficulty recording neural activity in early development.

31 different developmental requirements during early development.

32 ect the PWS-IC from DNA demethylation during early development.

33 highly similar morphological patterns during early development.

34 een CGI-containing and CGI-less genes during early development.

35 ects of leptin on NAG neurons in mice during early development.

36 ression, degradation, and translation during early development.

37 netic screens to uncover genes necessary for early development.

38 ly transcribed genes appear to drive A. suum early development.

39 mportant role in vertebrate and invertebrate early development.

40 ve assay for studying paracrine signaling in early development.

41 embryonic stem cell (mESC) pluripotency and early development.

42 ain that originates from the yolk sac during early development.

43 racterised downstream gene that is active in early development.

44 and the spreading of embryonic tissue during early development.

45 somatosensory information processing during early development.

46 associated with their trunk segmentation and early development.

47 r the maturation of neuronal circuits during early development.

48 h their impact on wasp colony initiation and early development.

49 aly, cortical thinning, and blindness during early development.

50 on guidance or neuron differentiation during early development.

51 EM) sleep, a particularly prominent state in early development.

52 ialized functions with the microbiota and in early development.

53 activation of lineage specifying TFs during early development.

54 is critical for successful fertilization and early development.

55 uscle and peripheral nerve patterning during early development.

56 egging Effort required to obtain food during early development.

57 stress the importance of local TH action in early development.

58 and cell cycle progression anomalies during early development.

59 oordinated to regulate RNA metabolism during early development.

60 roRNAs may therefore play important roles in early development.

61 ereby demonstrating its potential utility in early development.

62 asticity independently from their effects on early development.

63 from ensembles of LGN neurons in cats across early development.

64 tages, including cotton fiber initiation and early development.

65 rgence in the regulation of pluripotency and early development.

66 ranscription of neural-specific genes during early development.

67 ive (or REM) sleep in mammals, especially in early development [1-4].

68 spatiotemporal structure that changes across early development [5].

69 S family with essential cytoplasmic roles in early development [6, 7].

70 obtained intriguing insights into the mouse early development, a holistic and systematic view is sti

71 Abnormal conditions during early development adversely affect later health.

72 ment found in neural progenitor cells during early development and adulthood, is regarded as a multip

73 t and in cells of the spiral ganglion during early development and adulthood.

74 Frontal fiber tracts displayed deviant early development and age-related changes that could und

75 cific regulations of Cg-Jmj mRNAs during the early development and along the reproduction cycle.

76 ts into the role of Wnt5a and Wnt11 in mouse early development and also in cancer metastasis, during

77 ed plasticity to stress exposure, such as in early development and at advanced age; and, second, the

78 ric neural tumors are often initiated during early development and can undergo very rapid transformat

79 Rapid cellular proliferation in early development and cancer depends on glucose metaboli

80 or the spreading behavior of tissues in both early development and cancer.

81 ffects that follow signaling cascades during early development and cell-restricted differentiation.

82 ain function and behaviour, highly active in early development and continuing throughout life.

83 opens up new possibilities for the study of early development and developmental disorders, but it ma

84 ental principles of PGC specification during early development and discuss how it is now possible to

85 Nearly all imprinted genes were imprinted in early development and either retained their parent-of-or

86 In humans, however, the early development and function of T cells in tissues rem

87 s showed enrichment of genes associated with early development and function of the nervous system.

88 mechanical cues play a critical role in the early development and functional maturation of cardiomyo

89 eterogeneity in cell function emerges during early development and how structural patterning goes han

90 ynamic chromatin regulatory landscape during early development and identifies key transcription facto

91 k3 was expressed in murine hair cells during early development and in cells of the spiral ganglion du

92 sed to normal chow or a high fat diet during early development and in postnatal life.

93 dows, hypoxia reduced copper toxicity during early development and increased its toxicity in hatched

94 family of postsynaptic MAGUK proteins during early development and is proposed to play a role in stab

95 Lin28A/B proteins are highly expressed in early development and maintain progenitor cells by block

96 b1 is essential for HSC specification during early development and maintenance in adults.

97 use of HIV envelopes circulating during the early development and maturation of breadth generated mo

98 n, decoding extracellular cAMP pulses during early development and may play a role in mediating cell-

99 o childhood disease onset, normal to delayed early development and slow to more rapid neurological de

100 Neochrome b and violaxanthin accumulated at early development and started to decrease two weeks befo

101 ntribute to deeper understanding of organism early development and survival as well as cancer.

102 of the methylome to maternal smoking during early development and the long-term impact of such expos

103 Arf6 activation through GluN2B-BRAG1 during early development and the transition from BRAG1- to BRAG

104 sion in neurons to extracellular cues during early development and throughout life.

105 e reduction of Gram-positive bacteria during early development and thus to a spatial distribution of

106 s crucial for stem cell function during both early development and tissue homeostasis throughout life

107 trin 3 declines significantly in CNS through early development and young adulthood before stabilizing

108 rsely, topo-II levels were unchanged through early development, and partial topo-II depletion led to

109 emosensory knowledge of their parents during early development, and retain chemical familiarity with

110 During early development, animal embryos depend on maternally d

111 the effects of beta-catenin/Wnt signaling in early development are exquisitely regulated by stage-dep

112 Light-dependent functions in early development are mediated by intrinsically photosen

113 These experiences, particularly during early development, are a significant risk factor for lat

114 pharmaceutical strategies in humans, both in early development as well as in late stage clinical tria

115 ontextual susceptibility appear to emerge in early development, as the interactive and adaptive produ

116 of the female gametophytes were arrested in early development, before mitosis 3, resulting in 45% of

117 in cortical bone quality and strength during early development (bone modeling) that persist during ad

118 Nav 1.2 are also present at the CNS nodes in early development but gradually diminish later.

119 ll to multicellular behavior is important in early development but rarely studied.

120 rals transiently control circuit assembly in early development, but it is thought that PC-to-PC conne

121 observed postures and movement timing across early development, but only when locomotor-driven stabil

122 The current study examined this skill in early development by measuring attention to eyes while v

123 Experiences during early development can influence neuronal functions and m

124 Simple manipulations during early development can influence these characteristics to

125 CTLA-4, anti-PD-1, anti-PD-L1, and others in early development, can unleash anti-tumor immunity and m

126 conditional knockout of neuroligin-3 during early development caused no detectable effect, mimicking

127 Lead exposure during early development causes neurodevelopmental disorders by

128 ar re-programming results in deregulation of early development checkpoints culminating in inefficient

129 1 is expressed in the neural crest region in early development, coinciding with early neuronal progen

130 f the bacterial microbiome and virome during early development, conditions that might influence these

131 nuclear size and the N/C volume ratio during early development contribute to the regulation of MBT ti

132 th global demethylation and remethylation in early development correlate with chromatin compartments.

133 onale, medicinal chemistry, preclinical, and early development data of this new class of GPR40 agonis

134 In early development, delayed and incomplete X chromosome i

135 Early development depends heavily on accurate control of

136 is starting to have on our understanding of early development, disease modeling, and potential thera

137 In early development, Drosophila melanogaster embryos form

138 Acute genetic disruption in early development, during the integration of post-embryo

139 Optimal periods during early development facilitate the formation of perceptual

140 Specifically, BPA reduces growth during early development, followed by a catch-up growth post-ju

141 of glaucoma filtration surgery, then in its early development from 1900 to 1920.

142 p1) is a ubiquitous homeoprotein involved in early development, genomic stability, insulin sensitivit

143 function of this transcription factor during early development has not been precisely defined.

144 ccess to human material, particularly during early development, has restricted researchers to only sc

145 ed that most, if not all, signals regulating early development have been identified.

146 SPNs during early development have high intrinsic excitability and r

147 ormula-fed girls from the Infant Feeding and Early Development (IFED) study.

148 l as it reduces mitochondrial segregation in early development, improving adult fitness by restrictin

149 atures during the 1st year of life constrain early development in 71 healthy typically developing inf

150 drastic elimination of serum/LIF ESCs during early development in comparison with 2i/LIF ESCs.

151 deficiency in neurotrophin signaling during early development in FXS.

152 ter understanding of iron homeostasis during early development in iron-refractory iron deficiency ane

153 assembly and delays nerve conduction during early development in mice.

154 programming of chromatin organization during early development in mice.

155 spond to a variety of sensory stimuli during early development in the egg capsule.

156 To study aberrations of early development in TSC, we generated induced pluripote

157 We find that E2a regulates early development in two ways.

158 ave begun to define a critical period during early development in which disruption of optimal host-co

159 rization of protein and mRNA dynamics across early development in Xenopus.

160 We demonstrate that early development in zebrafish embodies a time window ch

161 mental models, in human hypertension, and on early developments in new indications, which should indi

162 Novel interventional approaches in early development include carotid body ablation and arte

163 ll, zygotic exposure to venlafaxine disrupts early development, including brain function, and comprom

164 mbryonic exposure to venlafaxine accelerated early development, increased hatching rate and produced

165 Exposure to a xenobiotic during early development induced persistent fat accumulation vi

166 Fruit formation and early development involve a range of physiological and m

167 The attenuation of plasticity beyond early development is a formidable obstacle for conventio

168 odel in which nuclear size regulation during early development is a multi-mode process wherein nucleu

169 principle in biology is that the program for early development is established during oogenesis in the

170 Early development is governed by the ability of pluripot

171 Most early development is necessarily dyadic and intrinsicall

172 essential during mammalian embryogenesis and early development is one of the key activators of mTORC1

173 CRH hyper-signaling in the forebrain during early development is sufficient to increase response to

174 During early development, knock-outs were indistinguishable fro

175 d a greater likelihood of motor delay during early development (later age at walking), but they were

176 rchestrated by Xist RNA, whose expression in early development leads to transcriptional silencing of

177 ion typically occurs in somatic cells during early development, leaving the germline genome intact.

178 induced expression of oncogenic Kras during early development led to liver enlargement and hepatocyt

179 r oncogenic, stem cell/cancer stem cell, and early development loci--including ETV4, FOXM1, LSR, CD9,

180 pose that the antiandrogenic exposure during early development may similarly result in an increase of

181 ystems, such as isolated cell populations or early-development models.

182 During early development, modulations in the expression of Noda

183 Our results demonstrate that during early development, mother-infant interactions can immedi

184 ctivity of neuronal structures formed during early development must be actively maintained as the bra

185 During early development, neurotransmitters are important stimu

186 f metabolic single-cell heterogeneity during early development of a vertebrate embryo.

187 emic hematopoietic stem cells and during the early development of acute myeloid leukemia and other my

188 biotics might have a preventive role against early development of AD and that therapeutic approaches

189 n skin barrier function before or during the early development of AD is not fully understood.

190 regenerated skeletal structures, indicating early development of an approximate PD pre-pattern.

191 nation and modulate root architecture during early development of Arabidopsis seedlings.

192 risk of autism can provide insight into the early development of autism and have shown that characte

193 differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD).

194 spinal shock, BDNF sequestration resulted in early development of bladder hyperactivity, accompanied

195 tion of the immune system in controlling the early development of cancer and establish a fundamental

196 dence linking ATF3 to the suppression of the early development of cancer, and underscore the importan

197 In MSA, severe dysautonomia and early development of combined autonomic and motor featur

198 ct of the proximal social environment on the early development of communication and language.

199 e of cortical folding, may be related to the early development of connectivity.

200 (TBI) is an established risk factor for the early development of dementia, including Alzheimer's dis

201 ng genes in coffee fruits, mainly during the early development of endosperm of both C. arabica and C.

202 Studies of GRNs operating in the early development of euechinoid sea urchins have reveale

203 His professional life coincided with the early development of general and thoracic surgery to whi

204 nt role in importing iron into organs during early development of healthy mice.

205 ponse after ocular HSV-1 infection causes an early development of herpes stromal keratitis in NK1R(-/

206 cellular and molecular events that drive the early development of innate lymphoid cells (ILCs) remain

207 ate how socio-cognitive constructs influence early development of mathematical skills.

208 that indicates the predisposition towards an early development of metabolic syndrome in ca. 25% of he

209 reconstructed the cellular hierarchy during early development of mouse embryos, modeled the dynamic

210 The expression of Grem2 during the early development of mouse teeth and hair follicles and

211 us variable and sex, clinical phenotype, and early development of neurological and autonomic manifest

212 Early development of obesity predicted obesity in adulth

213 ak is likely to improve our understanding of early development of obesity.

214 n these index cases support a model in which early development of occult hippocampal hyperexcitabilit

215 The early development of our hypothesis focuses on an iridiu

216 an important source of nutrients during the early development of oviparous organisms.

217 eased incretin responses likely leads to the early development of postprandial hyperglycemia in CF.

218 metabolic derangements that occur during the early development of pressure overload-induced HF involv

219 n SMPDL-3b-dependent manner in vitro and the early development of proteinuria after xenogeneic kidney

220 at innate immunity is a leading actor in the early development of pulmonary changes in smoking mice a

221 d the oxytocin system in contributing to the early development of responding to social eye cues.

222 xicity of polystyrene nanoparticles (NPs) in early development of sea urchin embryos (Paracentrotus l

223 eas of NK1R(-/-) mice was associated with an early development of severe herpes stromal keratitis.

224 ophils have been implicated in promoting the early development of TH 2 cell responses in some murine

225 re we investigated the role of n1-src in the early development of the amphibian Xenopus tropicalis, a

226 of the somatic and neural elements following early development of the central nervous system.

227 togenic mesodermal and ectodermal domains in early development of the cidaroid Eucidaris tribuloides

228 vioral interventions could have an impact on early development of the CNS and immune system and contr

229 ges and rapidly decreasing cell sizes during early development of the embryo.

230 Early development of the endosperm in Austrobaileya is a

231 play a fundamental role in implantation and early development of the fetus and placenta, yet little

232 ors and I were enthused to contribute to the early development of the field and continue to be amazed

233 uggestive of a Shh-Vax1 feedback loop during early development of the forebrain and a likely mechanis

234 ffspring, potentially through its effects on early development of the infant microbiome.

235 Our results demonstrate that during early development of the olfactory system, radial glia p

236 slate into cell division activity during the early development of the organ.

237 actor 1a (PTF1a) plays a crucial role in the early development of the pancreas and in the maintenance

238 During early development of the PNS, Pals1-deficient mice had i

239 ned the function of nbeta-catenin during the early development of the sea star, which undergoes a bas

240 vation of GRN architecture was maintained in early development of the sea urchin lineage.

241 othelial and hematopoietic precursors during early development of the vascular system suggested the p

242 ation of Cd and Hg to female mice during the early development of their offspring (the periconception

243 gh-resolution imaging modality for analyzing early development of vertebrate embryos in vivo by using

244 s for PQBP1 and a binding partner, WBP11, in early development of Xenopus embryos.

245 During the early development of Xenopus laevis embryos, the first m

246 ally inclined and stimulated by the exciting early developments of scientific psychology, 2) consider

247 f Cd and Hg that were co-administered during early development on indices of chronic diseases in adul

248 Mice expressing HYAL1 in skin either during early development or by inducible transient expression e

249 ther N-glycosylated proteins are critical to early development, overexpression of TRPM7 in Xenopus la

250 We also offer a potential early development pathway for silk-based sustained deliv

251 During early development, PGCs are exposed to numerous signals

252 re still under clinical evaluation or in the early development phase.

253 that an absence of inhibitory balance during early development prevents the expression of the active

254 ound that these enhancers were permissive in early development prior to Pmp22 upregulation.

255 this short period of the GH exposure during early development produces persistent phenotypic, metabo

256 ensitivity is evident in multiple periods of early development, ranging from the first trimester of g

257 ptic influences from sensory synapses during early development regulates the density and organization

258 the embryo and how cell cycle timing impacts early development remain important, unanswered questions

259 onic development in mammals, its role during early development remains controversial.

260 rs that fashion TL in somatic tissues during early development should contribute to an understanding

261 Additionally, Lgdel (+/-) networks at early development show abnormal neuritogenesis and void

262 terior primitive streak specification during early development, significantly enhances the reprogramm

263 organism is exposed to pathogens during very early development, specific defense mechanisms must take

264 During early development, SR-BI is expressed in extraembryonic

265 of cucumber plants in hydroponic culture at early development stages to two concentrations of nano-C

266 w drugs to market with minimal investment in early development stages.

267 In early development, sterol efflux and the ganglioside GM1

268 ce of target diseases and the stage at which early development studies should be focused.

269 (age 19-21) from the UK-representative Twins Early Development Study (TEDS).

270 1,265 twin pairs from the Twins Early Development Study completed the novel "Bricks" tes

271 scent twins (18-19-years old) from the Twins Early Development Study were used to quantify genetic an

272 2865 twins aged 18-19 y from the TEDS (Twins Early Development Study), a large population-based cohor

273 January 1, 1994, to December 31, 1996 (Twins Early Development Study).

274 Participants were drawn from the Twins Early Development Study, a population-based cohort recru

275 ive sample of 8395 twin pairs from the Twins Early Development Study, recruited from population recor

276 1,215 18-year-old twin pairs from the Twins Early Development Study, we collected measures of two in

277 data from the population-based cohort Twins Early Development Study, which included all twin pairs b

278 16 years in 10,038 twin pairs from the Twins Early Development Study.

279 twin pairs from the UK representative Twins Early Development Study.

280 and myelin was seen in the lateral column in early development, suggesting that there may also be a r

281 Here we report that, during early development, superficially positioned Reelin-expre

282 to be a single point replacement for routine early development testing which previously combined elem

283 erience site-specific thermal regimes during early development that could be disrupted by warming.

284 ral cycles of rapid furrow ingression during early development that culminate in the formation of an

285 While macroH2As are not required for early development, the absence of macroH2As impairs pren

286 Thus, together with its role in early development, the dynamic regulation of m(6)A in th

287 Here, we show that during early development, the sea urchin ANE territory separate

288 Building on lessons taken from early development, this monolayer-directed differentiati

289 n formation of the nervous system, from very early development through adolescence.

290 the thioredoxin DHD plays a critical role in early development to facilitate the switch from protamin

291 They are transcriptionally silenced during early development to protect genome integrity and aberra

292 nabling the evaluation of novel compounds in early development to select doses and schedules.

293 We examined the regulatory role of miR-31 in early development using the sea urchin as a model.

294 ural cells investing the dorsal aorta during early development using the zebrafish.

295 ine, which arrests after clonal expansion in early development, variance in the mutant proportion is

296 that the reduction in copper toxicity during early development was independent of copper uptake, whil

297 on the suppression of copper toxicity during early development, we stabilized the hypoxia inducible f

298 peak capacity for a body system, starting in early development when plasticity permits changes in str

299 ng nucleus size is a particular challenge in early development, where the nucleus must downscale in s

300 role of the amygdala on the HPA axis during early development, which fits with emerging literature o