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1                              However, unlike early embryonic ablations, the growth plates of these mi
2             We recently reported that in the early embryonic absence of N-Myc (using Pax2-Cre), hair
3 er tritiated thymidine ([(3)H]dT, or TdR) at early embryonic ages were killed at different intervals
4 ce of these important cells and what are the early embryonic ancestors of definitive HSCs?
5  DNA glycosylase (TDG) play crucial roles in early embryonic and germ cell development by mediating D
6 ction and is dynamically reprogrammed during early embryonic and germ cell development.
7  that adult LCs have a dual origin, bridging early embryonic and late fetal myeloid development.
8 nscriptional activators or repressors during early embryonic anterior-posterior patterning.
9 oduce human NT-ESCs have failed secondary to early embryonic arrest of SCNT embryos.
10 cytes, highly abnormal Ca(2+) transients and early embryonic arrest.
11 dentify a genetic network that reinforces an early embryonic bias in auxin distribution to create a l
12 esenchyme exerts a considerable influence on early embryonic brain development and its disruption con
13 nurenine metabolism plays a critical role in early, embryonic brain development, although fewer effec
14 osphatases during progression throughout the early embryonic cell cycle and shed new light on potenti
15 phosphorylation is restricted throughout the early embryonic cell cycle, not just during M-phase, and
16 ses AurA(Thr-295) phosphorylation during the early embryonic cell cycle.
17                                        Fast, early embryonic cell cycles have correspondingly fast S
18 opic geminin slows down, but neither arrests early embryonic cell cycles nor affects endogenous gemin
19  on the chiral twist that takes place during early embryonic cell divisions.
20 e loss of AURKB, to support both meiotic and early embryonic cell divisions.
21                                To define the early embryonic cell population that responds to Mesp1,
22 onstrate that the two daughter cells of many early embryonic cell-doubling events contribute asymmetr
23                                        Using early embryonic cells to determine the functional relati
24               During the short interphase of early embryonic cells, AL are rapidly delivered into the
25 y-breaking processes observed in oocytes and early embryonic cells.
26 RVK can induce viral restriction pathways in early embryonic cells.
27 l platform for in vitro investigation of the early embryonic cellular response to ionizing radiation.
28 e anterior cerebellar neuroepithelium in the early embryonic cerebellum was expanded and that granule
29  Differential conditional deletion of Sp2 in early embryonic cerebral cortical progenitors, and perin
30 n in the nematode Ascaris suum occurs during early embryonic cleavages and leads to the loss of germl
31 1 in the peripheral nervous system, using an early embryonic conditional knock-out model in which the
32                                        These early embryonic CSF1R(+)CD19(+) ProB cells also express
33 is from the yolk sac and enter the CNS quite early (embryonic day 9.5-10 in mice).
34                          Those succumbing to early embryonic death had markedly deformed vasculature
35 n mice results in failed lumen formation and early embryonic death through an endothelial cell autono
36 velopment is severely impaired, resulting in early embryonic death.
37 ection causes arrest before gastrulation and early embryonic death.
38 ene in the genome for which PatDp results in early embryonic death.
39 lt in synthetic lethality and, in the mouse, early embryonic death.
40 or impractical if homozygous mutations cause early embryonic defects.
41 ryonic stem (ES) cell line that emulates the early embryonic demethylation and remethylation waves.
42  of PRC2 components have been complicated by early embryonic dependence on PRC2 activity and the part
43                 Our results demonstrate that early embryonic depletion of LAP1 does not impair myogen
44 emature burst of granule neurogenesis during early embryonic development accompanied by increased cel
45 ated the expression of specific miRNA during early embryonic development and between in vivo (IVO) an
46 ne-disrupting properties, may pose a risk to early embryonic development and cellular homeostasis dur
47 ome data set of bovine oocyte maturation and early embryonic development and detailed insight into th
48 DNA replication is crucial during C. elegans early embryonic development and further provide a novel
49       tor1 was expressed ubiquitously during early embryonic development and in multiple adult tissue
50 ning embryonic stem cell pluripotency during early embryonic development and it is required for gener
51  minimum, fully substantiate L1 mosaicism in early embryonic development and neural cells, including
52 ctors are essential for diverse processes in early embryonic development and organogenesis.
53  basic activity of kcnh1 that is crucial for early embryonic development and patterning.
54 ental step toward understanding the bases of early embryonic development and pluripotency.
55 tion of mature oocytes capable of undergoing early embryonic development and successful pregnancy.
56  highly efficient splicing during Drosophila early embryonic development and suggest in highly prolif
57 ls, Set1A has been shown to be essential for early embryonic development and the maintenance of embry
58                     Cripto-1 is critical for early embryonic development and, together with its ligan
59    mRNAs required for meiotic maturation and early embryonic development are stored in growing oocyte
60       We analysed TSS usage during zebrafish early embryonic development at high resolution using cap
61                                              Early embryonic development features rapid nuclear DNA r
62 acterizing Dicer and miRNA expression during early embryonic development from IVO and IVF sources are
63 st pronounced for gene regulatory domains of early embryonic development genes, housekeeping genes, a
64        Our understanding of reproduction and early embryonic development has directly enabled our man
65 esses and multi-lineage specification during early embryonic development have also been uncovered.
66  machinery, and that Donson is essential for early embryonic development in mice as well, suggesting
67 isruption of a CSN gene causes arrest during early embryonic development in mice.
68      It is essential for differentiation and early embryonic development in mice.
69 n, we performed a transcriptomic analysis of early embryonic development in the spider Parasteatoda t
70                                              Early embryonic development in zebrafish is characterize
71                                              Early embryonic development is characterized by rapid cl
72                           In most metazoans, early embryonic development is characterized by rapid mi
73                                              Early embryonic development may be a particularly suscep
74        Oocyte maturation, fertilization, and early embryonic development occur in the absence of gene
75                                     However, early embryonic development occurs in the absence of tra
76 maintenance of embryonic stem (ES) cells and early embryonic development of the mouse.
77 d the effects of low frequency vibrations on early embryonic development of two aquatic species, Xeno
78 wever, their roles in cell fate decisions in early embryonic development remain poorly understood.
79 cluding SOX9, SF1, SOX8, AMH and DMRT1 in an early embryonic development stage at E34 in the XY(DSD)
80            Our findings indicate that during early embryonic development the precise timing of gene e
81 s involved in cell fate specification during early embryonic development through regulating mRNAs inv
82 tors, including Wnt proteins, operate during early embryonic development to induce the NC cell fate.
83 l responsible for organizing activity during early embryonic development, and is necessary for bilate
84 mber to provide an essential function during early embryonic development, and that other family membe
85   Almost all Armc5 knockout mice died during early embryonic development, around 6.5 and 8.5 days.
86                                       During early embryonic development, atRA is synthesized from al
87 tional modification plays a critical role in early embryonic development, but its functions in C&E mo
88 ulation plays a crucial role in germline and early embryonic development, but the underlying mechanis
89 Zygote arrest (Zar) proteins are crucial for early embryonic development, but their molecular mechani
90 as started to emerge, with altered levels in early embryonic development, embryonic stem (ES) cell di
91                                 Thus, during early embryonic development, NT-4 produced in the gangli
92                                       During early embryonic development, one of the two X chromosome
93                                       During early embryonic development, pHSCs migrate into the feta
94 d protein 1 (CDK2AP1), an essential gene for early embryonic development, plays a role in pluripotenc
95 gene expression gradually strengthens during early embryonic development, reaching its peak at the po
96 transport and local translation required for early embryonic development, synaptic plasticity, and lo
97   To further investigate the role of Zic3 in early embryonic development, we utilized two model syste
98  deleterious pleiotropic effects of altering early embryonic development--the precise time when male-
99 ription and changes to the cell cycle during early embryonic development.
100 t marsupials also have a placenta to mediate early embryonic development.
101  stalling promotes repeat instability during early embryonic development.
102 ghly expressed in the CNS, especially during early embryonic development.
103 se, a unique "chanzyme," required for proper early embryonic development.
104 n parental genomes contribute differently to early embryonic development.
105  critical for normal cilium formation during early embryonic development.
106 tional programs critical for angiogenesis in early embryonic development.
107 ally expressed and widely distributed during early embryonic development.
108 est whether Hif-1alpha also was required for early embryonic development.
109 blish a concentration gradient in Drosophila early embryonic development.
110 ad mutations in Atm (Atm(KD/KD)) died during early embryonic development.
111 required for inner cell mass survival during early embryonic development.
112 basal levels display oscillations throughout early embryonic development.
113  implications for cell fate decisions during early embryonic development.
114 tion in heterochromatin during oogenesis and early embryonic development.
115 lly redundant in ES cell differentiation and early embryonic development.
116 germ line, but it is required maternally for early embryonic development.
117  caused by a somatic mutation arising during early embryonic development.
118 sition can occur in the germ line and during early embryonic development.
119 ing pathway to promote oocyte maturation and early embryonic development.
120 e rod-like structure of the notochord during early embryonic development.
121 demonstrated that beta-actin is required for early embryonic development.
122 hat Nv-TLR also has an essential role during early embryonic development.
123  to regulate diverse aspects of germline and early embryonic development.
124 oral lobar degeneration and is essential for early embryonic development.
125 processes as diverse as learning, memory and early embryonic development.
126 est that cyclin H has important functions in early embryonic development.
127           In addition, Cul4A is required for early embryonic development.
128                    Abundant cell death marks early embryonic development.
129 it paternally acquired phenotypes by shaping early embryonic development.
130 chanisms regulating X chromosome activity in early embryonic development.
131  throughout Drosophila oocyte maturation and early embryonic development.
132 in ovarian functions, oocytes, ovulation and early embryonic development.
133  with a bias against truncating mutations in early embryonic development.
134 ipto-1/FRL-1/Cryptic family, is critical for early embryonic development.
135 lls (mESCs) is a valuable in vitro model for early embryonic development.
136 stence of similar regulations in vivo during early embryonic development.
137 ork underlies cell fate specification during early embryonic development.
138  xretpos(L)) being transcribed solely during early embryonic development.
139 ritical for setting up pluripotent states in early embryonic development.
140 d specificity for five Drosophila TFs during early embryonic development: Bicoid, Caudal, Giant, Hunc
141 Malpighian tubules is not established during early embryonic development; instead, pluripotent progen
142  the degree to which the networks regulating early embryonic differentiation are conserved.
143 genitor cells is distinct from that found in early embryonic divisions and is more similar to that of
144 e a small RNA-Argonaute pathway that ensures early embryonic divisions in C. elegans by employing cat
145                      We show that during the early embryonic divisions in C. elegans, ring constricti
146 fy genes that affect NPC distribution during early embryonic divisions.
147 inheritance to active segregation during the early embryonic divisions.
148 ct chromosomes during egg meiotic arrest and early embryonic divisions.
149 romosome segregation during gametogenesis or early embryonic divisions.
150 es affect anaphase timing differently in the early embryonic divisions.
151 6 hpf (shield stage) leads to impacts on the early embryonic DNA methylome; and (3) TDCIPP-induced im
152  inhibition of hedgehog (Hh) activity in the early embryonic endoderm is a prerequisite for pancreati
153 onstitute a plausible causal pathway linking early embryonic environment, epigenetic alteration, and
154 ial for embryo production, cell division and early embryonic events are frequently reused later in em
155 focused on identifying compounds that affect early embryonic events in Caenorhabditis elegans We iden
156 ng either prior or post spermatogenic, i.e., early embryonic events.
157 develop normally and are tumor-free, whereas early embryonic expression of Nras G12D/+ is lethal.
158                      This is consistent with early embryonic expression of PIPKIalpha and PIPKIgamma
159        Nix exhibits persistent M linkage and early embryonic expression, two characteristics required
160 okadaic acid (OA) or fostriecin into Xenopus early embryonic extract revealed that phosphatase activi
161 embryogenesis and is an integral part of the early embryonic gene regulatory network in S. purpuratus
162 es the reprogramming process and reactivates early embryonic genes.
163 nd together facilitate the remodeling of the early embryonic genome.
164              Pregestational diabetes retards early embryonic growth.
165 ike progenitors that faithfully recapitulate early embryonic haematopoiesis.
166 o decipher the molecular pathways that drive early embryonic haematopoiesis.
167 ies define the ETS expression profile in the early embryonic heart and identify an ETS-dependent enha
168    In contrast, we propose here that, in the early embryonic heart tube, the signaling mechanism coor
169  ERG, and ETV6 were the most abundant in the early embryonic heart.
170                       Wnt signaling controls early embryonic hematopoiesis and dysregulated beta-cate
171 acity originate and differentiate within the early embryonic kidney by hemovasculogenesis (the concom
172                                              Early embryonic labeling with lineage-marker-bearing tra
173 e required to understand the extent to which early embryonic landscapes are conserved.
174  Targeted deletion of the murine Acf gene is early embryonic lethal and Acf(-/-) blastocysts fail to
175                   Mice with mWh knockout are early embryonic lethal and display DNA damage.
176     However, because Runx1 knockout mice are early embryonic lethal due to failure of hematopoiesis,
177 mutants were identified as null mutants with early embryonic lethal phenotypes that could be rescued
178                 Smg1 homozygous KO mice were early embryonic lethal, but Smg1 heterozygous mice showe
179 ygous null for the alpha2(V) gene Col5a2 are early embryonic lethal, whereas haploinsufficiency cause
180 ad a normal lifespan, while homozygotes were early embryonic lethal.
181  Here we show that loss of Prmt5 function is early embryonic-lethal due to the abrogation of pluripot
182 sium homeostasis but additionally results in early embryonic lethality and neural tube closure defect
183                                     To avoid early embryonic lethality and study NFP function in late
184  inactivation of Atm and H2ax in mice causes early embryonic lethality associated with substantial ce
185                    In marked contrast to the early embryonic lethality associated with the genetic di
186 HD homozygous null (BHD(d/d)) mice displayed early embryonic lethality at E5.5-E6.5, showing defects
187                     Absence of ALK5 leads to early embryonic lethality because of severe defects in v
188 reased TRPM7 expression, indicating that the early embryonic lethality caused by loss of hepatocystin
189     The mouse Hinfp(LacZ) null allele causes early embryonic lethality due to a blastocyst defect.
190  This disruption of Jab1 in mice resulted in early embryonic lethality due to accelerated apoptosis.
191 emonstrated in EPCR knockout mice which show early embryonic lethality due to placental thrombosis.
192 olk sac vasculogenesis as a primary cause of early embryonic lethality following loss of this critica
193 ecause germ line deletion of Flcn results in early embryonic lethality in animal models.
194 1) is expressed by osteoblast-lineage cells; early embryonic lethality in Bag-1 null mice, however, h
195 RBP with a putative role in splicing, causes early embryonic lethality in mice and that its loss in P
196                  Deletion of Lig3 results in early embryonic lethality in mice, as well as apparent c
197 mice, both D2899A and Q2740P mutations cause early embryonic lethality in mice, without displaying do
198 y, elevated p53 transcriptional activity and early embryonic lethality in mice.
199 ted cell cycle inhibition contributes to the early embryonic lethality in the Rbx1-deficient embryos.
200 normal cell cycle progression and results in early embryonic lethality in vertebrates.
201                           Due in part to the early embryonic lethality of Dnmt1 and Uhrf1 knockout mi
202                           In contrast to the early embryonic lethality of H2AX(-/-)XLF(-/-) mice, 53B
203                                 However, the early embryonic lethality of Hand2-null mice has preclud
204 o play a role in patterning blood formation, early embryonic lethality of mice lacking Hh signaling p
205                                              Early embryonic lethality of the mouse knockout challeng
206 tes are perinatal lethal, in contrast to the early embryonic lethality previously reported for Rnaseh
207 xically, BRCA1 deficiency in mice results in early embryonic lethality, and similarly, lack of BRCA1
208 ould lead to degradation of type I collagen, early embryonic lethality, and the scarcity of reported
209      Whereas complete loss of Spartan causes early embryonic lethality, hypomorphic mice with low amo
210     Although NIR deficiency in mice leads to early embryonic lethality, lymphoid-restricted deletion
211              While TDP-43 knockout mice show early embryonic lethality, post-natal conditional knocko
212                 Deletion of CDK2AP1 leads to early embryonic lethality, potentially through altered d
213 oliferate, whereas deletion from mice causes early embryonic lethality, raising the question of wheth
214 utive Ssb1/Ssb2 double knockout (DKO) caused early embryonic lethality, whereas conditional Ssb1/Ssb2
215 ozygous TRPM7(Deltakinase) mice demonstrated early embryonic lethality, whereas heterozygous mice wer
216 oviding a molecular explanation for htt(-/-) early embryonic lethality.
217 disease (HD), while htt(-/-) mutants display early embryonic lethality.
218 P1 receptor agonist to pregnant dams rescued early embryonic lethality.
219 g leads to complex developmental defects and early embryonic lethality.
220 ells, and germ-line deletion of Palb2 led to early embryonic lethality.
221 specific loss-of-function of YY1 resulted in early embryonic lethality.
222 hat Rdh10 loss-of-function mutations lead to early embryonic lethality.
223 uding exocytosis and cytokinesis, leading to early embryonic lethality.
224 ar as inactivation of murine Lig3 results in early embryonic lethality.
225 f this gene in higher vertebrates results in early embryonic lethality.
226  genetic inactivation of CycK in mice causes early embryonic lethality.
227    Global Ptpn11(E76K/+) mutation results in early embryonic lethality.
228 homozygous Brca2 mutation typically leads to early embryonic lethality.
229 ound deficiency of both Jnk1 and Jnk2 causes early embryonic lethality.
230 ited formation of abnormal actin bundles and early embryonic lethality.
231 etion from the adrenal gland that results in early embryonic lethality.
232 n of the TRP channel TRPM7, which results in early embryonic lethality.
233 ound that loss of functional Zbtb24 leads to early embryonic lethality.
234 knockout of both paralogs in mice results in early embryonic lethality.
235  and show that Slc52a3 deficiency results in early embryonic lethality.
236  demonstrated that deletion of Ada3 leads to early embryonic lethality.
237  H3.3 leads to developmental retardation and early embryonic lethality.
238 t the postimplantation stage, which leads to early embryonic lethality.
239 o E19, increased thereafter, and rose to the early embryonic level in the adult cornea.
240 lopment of the neocortex in p73 KO mice from early embryonic life into advanced age (25 months).
241 erentiation and further our understanding of early embryonic lineage segregation.
242 iate neural crest specification from various early embryonic lineages in Xenopus and chicken embryos
243 mice lacking NLRP2 are subfertile because of early embryonic loss and the production of fewer offspri
244 development, we specifically deleted Pten in early embryonic lung mesenchyme in mice.
245 except FoxQ1, are involved in patterning the early embryonic mesoderm.
246 nize in vitro, but whether they can recreate early embryonic morphogenesis is unclear.
247 ome profiling demonstrates that, in general, early embryonic mRNAs are not stored for subsequent tran
248 ls isolated from these tumors that formed in early embryonic murine retinas were characterized.
249 normal blood from 241 adults to identify 163 early embryonic mutations.
250 onnexin (Cx) 45 is strongly expressed in the early embryonic myocardium.
251  that pathological processes taking place in early embryonic neurodevelopment might be responsible fo
252  the IgLON family, neurotrimin and NEGR1, in early embryonic neurons was sufficient to confer sensiti
253           Recent findings suggest AMs are of early embryonic or fetal origin.
254             GIP signaling may play a role in early embryonic pancreas differentiation to form insulin
255          We find that Hes1 expression in the early embryonic pancreas identifies multipotent, Notch-r
256 d7 were all broadly expressed throughout the early embryonic pancreatic epithelium.
257                                              Early embryonic patterning events are strikingly precise
258 f broad developmental regulators followed by early embryonic patterning genes and culminating in the
259 y of work aimed at understanding the role of early embryonic patterning genes in organizing adult res
260  and its sexually derived endosperm regulate early embryonic patterning in flowering plants.
261      The involvement of these protrusions in early embryonic patterning is suggested by the discoveri
262 r of developmental signaling pathways during early embryonic patterning.
263                                   During the early embryonic period, neuroblasts generate the primary
264                                              Early embryonic piwi-1+ cells are molecularly and functi
265      Imprinted genes have been implicated in early embryonic, placental, and neonatal development and
266 amily provides insight into the evolution of early embryonic potency.
267                        This study reveals an early embryonic regional specification of postnatal neur
268 morphogenesis in the epithelial tissue of an early embryonic salivary gland at a local scale using an
269 in early human embryos, our understanding of early embryonic somatic mutations is very limited.
270      Conditional ablation of COUP-TFII at an early embryonic stage resulted in failed formation of pr
271 he epithelium of the tongue primordium at an early embryonic stage, acquire epithelial cell phenotype
272 oxa1 is expressed very transiently during an early embryonic stage, it has been difficult to determin
273 opulations exhibit immature properties of an early embryonic stage, raising concerns about their abil
274 aboral (O-Ab) axis first develops during the early embryonic stage.
275  invade the mammalian spinal cord (SC) at an early embryonic stage.
276 t, but its boundary to the embryonic body at early embryonic stages and the fate of cells constitutin
277 dantly to regulate the generation of RGCs at early embryonic stages as well as the survival of RGCs a
278 ll RNA expression from the ovary and several early embryonic stages by deep sequencing followed by co
279 stological analysis of BMPER(-/-) embryos at early embryonic stages demonstrates that commencement of
280 nalling in the distal limb primes the ZRS at early embryonic stages maintaining a poised, but inactiv
281 ociated with the calyceal processes from the early embryonic stages of outer segment growth onwards.
282 nt sympathetic neurons die by apoptosis from early embryonic stages to perinatal stages.
283                                           At early embryonic stages, high Ctbp2 levels sustain Notch
284                                         From early embryonic stages, immune cells are faced with a ba
285 les (CRMs) than the coactivator p300, during early embryonic stages.
286 and mixed ancestry of these brain regions at early embryonic stages.
287 er, about the possible actions of NGF during early embryonic stages.
288 cial role in microglial establishment during early embryonic stages.
289 and TrkA(+)/TrkC(+) double positive cells at early embryonic stages.
290     However, comparative studies focusing on early/embryonic stages during insect development are lim
291 uce a new molecular player in the context of early embryonic stem cell state and cell fate determinat
292                The mouse node is a transient early embryonic structure that is required for left-righ
293 yclin A2 loss lead to increased apoptosis at early embryonic time points but not at post-natal time p
294 oteinase 9 (MMP9) is expressed in teeth from early embryonic to adult stage.
295  transgenic reporting methods to analyze the early embryonic transcription factor T-box gene 4 (TBX4)
296 l, paternal and zygotic contributions to the early embryonic transcriptome, we sequenced the transcri
297         In zebrafish, twist was expressed in early embryonic vasculature where it promoted angiogenes
298 s reminiscent of local activation of Toll in early embryonic ventral hypoderm, consistent with the hy
299 ed that ISL1 within SAN is a requirement for early embryonic viability.
300                         Using four stages of early embryonic zebrafish development, we map nucleosome

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