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1 al 5998 patients (3042 before and 2956 after early goal-directed therapy).
2 with an early resuscitation protocol such as early goal-directed therapy.
3 severe sepsis and septic shock treated with early goal-directed therapy.
4 tion, severity of illness, and initiation of early goal-directed therapy.
5 Studies that evaluated early goal-directed therapy.
6 rgest roadblocks to overcome in implementing early goal-directed therapy.
7 Early goal-directed therapy.
8 lled patients, 130 were randomly assigned to early goal-directed therapy and 133 to standard therapy;
9 ssociated with mortality differences between early goal-directed therapy and control included Acute P
10 ions such as 24-hr intensivist availability, early goal-directed therapy, and renal replacement thera
11 ppropriate antibiotic co-intervention in the early goal-directed therapy arm compared with controls i
14 ty was 30.5 percent in the group assigned to early goal-directed therapy, as compared with 46.5 perce
15 ectrum antibiotics within 4 hrs; c) complete early goal-directed therapy at 6 hrs; d) give corticoste
16 f this study was to evaluate the efficacy of early goal-directed therapy before admission to the inte
17 dance was not associated with differences in early goal-directed therapy bundle compliance or hemodyn
18 s prompt recognition and aggressive therapy; early goal-directed therapy decreases morbidity and mort
19 pathway incorporating empirical antibiotics, early goal-directed therapy, drotrecogin alfa, steroids,
22 re treated according to a 6-hour protocol of early goal-directed therapy (EGDT), in which intravenous
24 al and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality fr
26 to implementation of a written protocol for early goal-directed therapy for severe sepsis in the bus
28 from 7 to 72 hours, the patients assigned to early goal-directed therapy had a significantly higher m
32 omized trial showed decreased mortality with early, goal-directed therapy in septic shock, a strategy
33 rotocol incorporating empirical antibiotics, early goal-directed therapy, intensive insulin therapy,
34 indicates a 98% probability (p = .038) that early goal-directed therapy is cost-effective at a willi
38 septic shock to receive either six hours of early goal-directed therapy or standard therapy (as a co
40 likely to endorse lack of agreement with the early goal-directed therapy resuscitation protocol (16%
41 abstracts (4429 patients) after the original early goal-directed therapy study were identified from a
42 gan dysfunction, in the patients assigned to early goal-directed therapy than in those assigned to st
43 izations developed management guidelines for early goal-directed therapy that would be of practical u
44 psed times from triage and qualification for early goal-directed therapy to administration of appropr
45 antibiotic administration, qualification for early goal-directed therapy to antibiotic administration
46 e from triage or time from qualification for early goal-directed therapy to antibiotics and mortality
47 biotic administration, and qualification for early goal-directed therapy to appropriate antibiotic ad
48 ; similarly, for time from qualification for early goal-directed therapy to appropriate antibiotics,
49 These findings are superior to the original early goal-directed therapy trial which showed figures o
51 The analysis from 37 studies showed that early goal-directed therapy was associated with a 23% re
54 g the five quality indicators, completion of early goal-directed therapy was significantly associated
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