ライフサイエンスコーパス: eccentric

1 oth are missing in a group of mutants called eccentric.

2 ty is delayed compared to that at 30 degrees eccentric.

3 ting the periastron passage of its extremely eccentric 111.4-day orbit.

4 ircle) main-sequence companion in a slightly eccentric 3.45-day orbit (M(middle dot in circle), solar

5 20 and 69% as massive as the Sun and have an eccentric 41-day orbit.

6 uzzle is why many of their orbits are highly eccentric; all planets in our Solar System are on nearly

7 lative to baseline was 10, 16 and 16 % after eccentric and 11, 9 and 10 % after mixed training (all P

8 ht volunteers performed 40 maximal voluntary eccentric and 40 maximal voluntary concentric elbow flex

9 At baseline, 17% of children had LVH (11% eccentric and 6% concentric) and 9% had concentric remod

10 thway uniquely regulates the balance between eccentric and concentric growth of the heart.

11 remodeling, women exhibit a mixed pattern of eccentric and concentric remodeling.

12 The remainder, on highly eccentric and inclined orbits, are more difficult to det

13 rate of strength recovery was faster and the eccentric and isometric strength gains greater.

14 With eccentric and mixed compared with concentric retraining

15 tracked two targets that started 1.5 degrees eccentric and moved in different directions (up, right,

16 Eccentric and uniform high-signal-intensity patterns wer

17 e, 9 asymmetrical, 3 concentric, 1 apical, 1 eccentric), and prognosis (premature sudden death in 2 i

18 ning that was 1 cm or greater and was focal, eccentric, and enhancing had a specificity of 92% but a

19 y at 10 degrees, 20 degrees , and 30 degrees eccentric are concurrent.

20 is traditionally classified as concentric or eccentric based on LV relative wall thickness.

21 ring surgery on the basis of the location of eccentric blood flow contact with the aortic wall, as de

22 l coherence and (ii) shifted their pRFs more eccentric but (iii) scaled their pRF sizes in variable w

23 We found that CFKO mice develop eccentric cardiac hypertrophy (normal LV wall thickness

24 cific role for MEK5-ERK5 in the induction of eccentric cardiac hypertrophy and in transduction of cyt

25 airments of cardiac contraction with greater eccentric cardiac hypertrophy in CPT1b(+/-) mice than in

26 ctivated MEK5 in transgenic mice resulted in eccentric cardiac hypertrophy that progressed to dilated

27 , G4D mice developed overt heart failure and eccentric cardiac hypertrophy, associated with significa

28 c imaging showed TTNtv to be associated with eccentric cardiac remodeling.

29 +/- 4.2; multidetector CT 28.4% +/- 2.8) and eccentric (cardiac MR 23.2% +/- 2.0; multidetector CT 24

30 trated that CD48-CD2 and CD48-CD22 induce an eccentric CD2/T cell antigen receptor cluster.

31 terms of cellular S values in concentric and eccentric cell-nucleus arrangements and by comparing the

32 nce imaging T1- and T2-weighted images after eccentric challenge, as well as greater decrement in bic

33 oids (beta-15'-apocarotenoids, C20), whereas eccentric cleavage by BCO2 produces long-chain (>C20) ap

34 Eccentric cleavage of beta-carotene at non-central doubl

35 Eccentric cleavage of beta-carotene occurs at double bon

36 demonstrated that beta-apo-13-carotenone, an eccentric cleavage product of beta-carotene, antagonizes

37 Immobilization reduced eccentric, concentric and isometric strength by 47 %.

38 n and after 12 weeks of retraining with 1866 eccentric, concentric or mixed contractions.

39 Moreover, the ability of ALLINIs to induce eccentric condensate formation required both IN and vira

40 Fifth, vRNA is necessary for ALLINI-induced eccentric condensate formation.

41 Eccentric condensates have a high NC content, as demonst

42 We conclude that eccentric condensates represent nonpackaged vRNPs and th

43 s block vRNP packaging; instead, vRNPs form "eccentric condensates" outside the core.

44 turation, resulting in virions that contain "eccentric condensates," electron-dense aggregates locate

45 In two eyes with central and eccentric cones, a standard broad-beam CXL protocol was

46 silica template that spontaneously takes an eccentric configuration during annealing.

47 GAS were delivered intravenously 48 h after eccentric contraction (EC)-induced injury of murine hind

48 s increased elasticity but reduced force and eccentric contraction (ECC)-mediated damage in EOMs and

49 ology studies with twitch force, tetanic and eccentric contraction all being normal.

50 ated with the ventral groove blubber undergo eccentric contraction in order to stiffen and control th

51 ion while the muscle seems more resistant to eccentric contraction induced force drop, indicating a r

52 ties of muscle as evidenced by resistance to eccentric contraction mediated damage, and a reduction o

53 In situ eccentric contraction of tibialis anterior (TA) muscles

54 gulation plays in the biological response to eccentric contraction remains to be determined, as does

55 t these mice exhibit increased resistance to eccentric contraction-induced damage and reduced fatigue

56 to measure muscle strength and resistance to eccentric contraction-induced damage.

57 The data show that eccentric contraction-induced injury causes morphologica

58 minin-binding activity and susceptibility to eccentric contraction-induced injury in skeletal muscle.

59 reas loss of in vivo torque production after eccentric contraction-induced injury is associated with

60 tetanic force and was also more resistant to eccentric contraction-induced injury than mdx4cv extenso

61 increased muscle force and protected against eccentric contraction-induced injury.

62 ction as judged by reduced susceptibility to eccentric contraction-induced injury.

63 expression is sufficient to protect against eccentric contraction-induced injury.

64 ecific force and increased susceptibility to eccentric contraction-induced muscle damage compared wit

65 sferlin-deficient mice significantly reduces eccentric contraction-induced t-tubule damage, inflammat

66 l of ERK1/2 phosphorylation before and after eccentric contraction.

67 following a bout of resistance exercise with eccentric contractions (EC).

68 ally stimulated muscles from these mice with eccentric contractions (EC).

69 Thirty eccentric contractions (ECs) were imposed upon rat dorsi

70 the early molecular alterations in humans to eccentric contractions (ECs), a stimulus known to induce

71 on, mouse skeletal muscles were subjected to eccentric contractions (ECs).

72 ntly attenuates force loss owing to damaging eccentric contractions and repetitive isometric contract

73 high susceptibility to injury with repeated, eccentric contractions as well as inflammation, resultin

74 a single bout of 100 electrically stimulated eccentric contractions in vivo.

75 ch that the animals completed concentric and eccentric contractions involving the hindlimb musculatur

76 dicate that the activation of mTOR following eccentric contractions occurs through a PI3K-PKB-indepen

77 tion, resulting in negative velocities as in eccentric contractions of whole muscle.

78 actions, even though the stress level of the eccentric contractions varied over a three-fold range an

79 force was not improved but the resistance to eccentric contractions was significantly stronger.

80 cle damage and force loss following repeated eccentric contractions when compared with mdx mice.

81 . d(-1)) after muscle-damaging exercise (300 eccentric contractions).

82 /Ankrd2 was dramatically upregulated only by eccentric contractions, but not by isometric contraction

83 ased nuclear P-ERK1/2 localization following eccentric contractions, but the archvillin-P-ERK1/2 asso

84 ctile overload (more specifically high-force eccentric contractions, i.e. CI) were compared side by s

85 ion, loss of torque production after in vivo eccentric contractions, or physical inactivity after mil

86 During eccentric contractions, wildtype mice exhibited a 36% lo

87 eclines in in vitro EDL force after repeated eccentric contractions.

88 s are depolarized after an injurious bout of eccentric contractions.

89 on potential generation and conduction after eccentric contractions.

90 rmal pattern of ERK1/2 phosphorylation after eccentric contractions.

91 ferences were detected between isometric and eccentric contractions.

92 llowing an acute bout of maximally activated eccentric contractions.

93 specific force generation and resistance to eccentric contractions.

94 ntinuously tuned from concentric core-shell, eccentric core-shell, acorn, to dimer structures.

95 masses, and predominantly solid masses with eccentric cystic foci should be examined at biopsy; 18 o

96 Of 38 predominantly solid masses with eccentric cystic foci, seven proved malignant.

97 cystic), or predominantly solid masses with eccentric cystic foci.

98 ength, but is protected from stretch-induced eccentric damage with age.

99 ic nondilated (increased M/EDV, normal EDV), eccentric dilated (increased EDV, normal M/EDV), concent

100 alyses, compared with normal LVM, those with eccentric dilated and both concentric nondilated and dil

101 categorized as eccentric nondilated in 12%, eccentric dilated in 20%, concentric nondilated in 29%,

102 d location, they turned their head toward an eccentric direction that also induced corresponding eye

103 o become bound to the black hole, forming an eccentric disk that quickly fragments to form stars.

104 Here we directed subjects' gaze (with an eccentric dot) or auditory attention (with lateralized n

105 have been accomplished if Charon's orbit was eccentric during most of this orbital evolution, with th

106 -defined, thin-walled, cystic lesion with an eccentric, echogenic focus in the subcutaneous plane.

107 e demonstrated increased muscle damage after eccentric exercise along with a decline in SC density an

108 o hyperalgesia in two ergonomic pain models (eccentric exercise and hindlimb vibration) and in a mode

109 daptive response of human skeletal muscle to eccentric exercise by differential modulation of a discr

110 High-force eccentric exercise results in sustained increases in cyt

111 older, but not younger, subjects performing eccentric exercise that causes an increase in skeletal m

112 ect in augmenting the neutrophil response to eccentric exercise, vitamin E causes a greater increase

113 n the use of progressive aquatic exercise or eccentric exercise.

114 re obtained 24 h before and 72 h after acute eccentric exercise.

115 of healthy individuals subjected to damaging eccentric exercise.

116 In addition, we found that eccentric eye positions were associated with enhanced pr

117 recordings of patients with nystagmus and an eccentric face turn who had undergone the Anderson-Keste

118 istered to the fovea re-established variable eccentric fixation that included the ectopic island of s

119 In patients with eccentric fixation, approximately 30% had a preferred re

120 e (high residual amblyopia) were presence of eccentric fixation, severe initial amblyopia, and no bin

121 sting patients with macular disease who have eccentric fixation.

122 Identification and characterization of eccentric flow jets in these patients may help identify

123 in response to pressure overload, develop an eccentric form of cardiac hypertrophy characterized by i

124 was developed for holding the eyes still in eccentric gaze positions to describe how the head is hel

125 e should be represented more reliably during eccentric gaze than while looking straight ahead.

126 ring the apparent shift of the bony orbit in eccentric gaze.

127 tion of the ONH and peripapillary tissues in eccentric gazes.

128 e that observed eccentric warm Jupiters with eccentric giant companions have mutual inclinations that

129 er 12 years, but those in the cluster A odd, eccentric group (schizoid, schizotypal, paranoid), and t

130 /-) Erk2(fl/fl-Cre) mice showed preferential eccentric growth (lengthening), whereas myocytes from Me

131 d by carcinoma often showed straightened and eccentric growth patterns, no thick fascia sign, and mor

132 nal intensity, central low signal intensity, eccentric high signal intensity, and uniform high signal

133 strictly defined diagnostic characteristics (eccentric hilum, longitudinal fissure, lack of fissure b

134 ific overexpression of PAR-1 in mice induced eccentric hypertrophy (increased left ventricular dimens

135 0th percentile but RWT >or=80th percentile), eccentric hypertrophy (LVM >or=80th percentile but RWT <

136 rtrophy (increased wall thickness and mass), eccentric hypertrophy (normal wall thickness and increas

137 Loss of myostatin induced eccentric hypertrophy and enhanced cardiac responsivenes

138 lomere shortening, results in de-compensated eccentric hypertrophy and heart failure in mice.

139 ase in cardiomyocyte length, associated with eccentric hypertrophy and ventricular dilation.

140 so had a higher prevalence of concentric and eccentric hypertrophy compared with non-Hispanic whites

141 of the TF gene in cardiomyocytes reduced the eccentric hypertrophy in mice overexpressing PAR-1.

142 nd volume overload results in concentric and eccentric hypertrophy of cardiac ventricular chambers wi

143 Progressive development of eccentric hypertrophy was observed, which subsequently r

144 Furthermore, these mice lacked eccentric hypertrophy, and their cardiomyocytes exhibite

145 In late pregnancy, hearts show eccentric hypertrophy, as expected for a response to vol

146 ncentric remodeling, concentric hypertrophy, eccentric hypertrophy, or normal geometry.

147 r TAC, RyR2(R4496C+/-) hearts responded with eccentric hypertrophy, substantial fibrosis, ventricular

148 Prohypertrophic Galphaq likewise caused eccentric hypertrophy, systolic dysfunction, and patholo

149 xpression of PAR-1 on cardiomyocytes induced eccentric hypertrophy.

150 29%, poor central in 2.4%, and predominantly eccentric in 29.27%.

151 eyes (81%), paracentric in 3 eyes (8%), and eccentric in 4 eyes (11%).

152 l MRI system and a high-resolution automated eccentric infrared photorefractor were used to analyze c

153 , whereas the autografts had only occasional eccentric intimal changes.

154 luntary quadriceps force was measured during eccentric, isometric, and concentric contractions.

155 0001), even when restricted to patients with eccentric jets (r = 0.93, p < 0.0001).

156 Patients with eccentric jets showed moderate agreement (kappa=0.53; 95

157 okinetic strength measures of concentric and eccentric knee flexion and extension, and concentric ank

158 HFrEF is characterized by greater eccentric LA remodeling, whereas HFpEF by increased LA s

159 is a volume-overload disease causing severe eccentric left ventricular (LV) hypertrophy and eventual

160 Eccentric left ventricular (LV) hypertrophy was present

161 24), subjects with high-output HF displayed eccentric left ventricular remodeling, greater natriuret

162 Mean remodeling ratio (vessel area/IMA) in eccentric lesions (E, n=28) was significantly larger tha

163 Remodeling ratio was consistently larger in eccentric lesions in all 3 vessel segments when analyzed

164 ant vasculopathy is significantly greater in eccentric lesions than in concentric lesions, possibly d

165 e x 10(3)) was also significantly greater in eccentric lesions versus concentric lesions (proximal 1.

166 Patients with thrombus, eccentric lesions, or lesion length >20 mm are at high r

167 ery was larger in vessels with predominantly eccentric lesions.

168 At lateral locations there was a central-eccentric location bias in the pointing task, and either

169 valent refraction from that obtained at each eccentric location.

170 lay activity when the gaze was shifted to an eccentric location.

171 Eccentric locations were in areas of loss of FDT sensiti

172 required to shift their gaze to one of four eccentric locations.

173 the frontal midline, with a decline at more eccentric locations.

174 s (</=3 regions of interest/eye), at 2 fixed eccentric loci, were imaged using AO, spectral-domain op

175 r adults results in increased plasma volume, eccentric LV hypertrophy, and systolic and diastolic dys

176 ied ARR as a key correlate of concentric and eccentric LV hypertrophy, consistent with a major role f

177 Acute BK2R blockade prevents eccentric LV remodeling and improves function.

178 Immediately after ACF induction, eccentric LV remodeling is mediated by interstitial coll

179 Chronic ACE inhibition does not prevent eccentric LV remodeling or improve function.

180 ced event-free survival in the subgroup with eccentric LVH at baseline (P = 0.034).

181 worse in the presence of concentric LVH and eccentric LVH compared with the absence of LVH (P = 0.00

182 prevalence of LVH at baseline was 47%, with eccentric LVH more frequent than concentric.

183 ction may aggravate the adverse prognosis of eccentric LVH.

184 ation of wave-guiding cones at the fovea and eccentric macular regions has prognostic and therapeutic

185 Moreover, combined eccentric medial disruption and ligation of the carotid

186 Hemodynamic disorders can result from eccentric mitral regurgitation usually caused by chordae

187 signals for high-intensity or maximal-effort eccentric movements differ from those for concentric act

188 individual electrode signals suggested that eccentric movements needed a significantly longer time f

189 vation pattern associated with maximal-level eccentric muscle actions.

190 ecific rs28357094 genotypes enrolled into an eccentric muscle challenge intervention [n = 3 TT; n = 3

191 Eccentric muscle contractions generate greater force at

192 pendent stiffening of titin stretched during eccentric muscle contractions.

193 Two cohorts of young adults-the Eccentric Muscle Damage (EMD; n = 156) cohort and the Fu

194 isolated a DNA fragment that complements the eccentric mutations.

195 Trojans were likely captured by a migrating, eccentric Neptune in a dynamically excited planetesimal

196 , a harmonic-based regression-model predicts eccentric NF-kappaB activity observed in the human inter

197 ly impair its binding to viral RNA result in eccentric, non-infectious virions without affecting nucl

198 ntric dilated (increased M/EDV and EDV), and eccentric nondilated (normal M/EDV and EDV)-and compared

199 lity or the composite end point, whereas the eccentric nondilated group did not.

200 At baseline, the LVs were categorized as eccentric nondilated in 12%, eccentric dilated in 20%, c

201 s at 10 degrees , 20 degrees, and 30 degrees eccentric, obtained using preferential looking procedure

202 It has been suggested that eccentric occlusal forces may be an etiologic factor for

203 significantly and positively associated with eccentric (odds ratio per SD increment, 1.20; 95% confid

204 These correlations were similar with eccentric or central jets (all P>0.60).

205 rchitectural remodeling can be classified as eccentric or concentric.

206 und in our Solar System; their orbits may be eccentric or inclined with respect to the host star's eq

207 njury, independent of contraction mode (i.e. eccentric or isometric).

208 -10 kilometres per second, suggesting highly eccentric or unbound trajectories if they are associated

209 The finding of focal, eccentric, or enhancing wall thickening had a sensitivit

210 elt object 1998 WW31 is binary with a highly eccentric orbit (eccentricity e approximately 0.8) and a

211 eriod P(1) = 1.76713 +/- 0.00019 days] on an eccentric orbit about a third star (mass M(A) = 1.347 +/

212 eleased at different locations in Enceladus' eccentric orbit is a crucial measurement of tidal contro

213 We find that the eccentric orbit of the Neptune-mass exoplanet GJ 436b is

214 ater when Enceladus is near the point in its eccentric orbit where it is furthest from Saturn (apocen

215 y discovered planet 2003 VB12 (Sedna) has an eccentric orbit with a perihelion distance of 70 au, far

216 ex the solid moon (rock plus ice) during its eccentric orbit, and that this heat entering the ocean d

217 the arcs affects the precession of Galatea's eccentric orbit, which will enable a mass estimate from

218 tries, 'kick' the nascent black hole into an eccentric orbit.

219 han predicted, which may indicate a slightly eccentric orbit.

220 by Enceladus as it moves around its slightly eccentric orbit.

221 Saccade disconjugacy also increased with eccentric orbital positions of the nonviewing eye.

222 Planets in significantly eccentric orbits can enable direct measurements of globa

223 Irregular satellites have eccentric orbits that can be highly inclined or even ret

224 e Oort cloud only after being perturbed into eccentric orbits that result in close encounters with th

225 cts of high-speed cometary dust particles on eccentric orbits, as opposed to particles of asteroidal

226 and could have scattered objects into large, eccentric orbits, no model currently explains the proper

227 which two show eclipses and two have highly eccentric orbits.

228 orbit close to their host star or in highly eccentric orbits.

229 Eccentric outflow jet patterns in BAV patients resulted

230 we show that the viral RNA genome and IN in eccentric particles are prematurely degraded, whereas re

231 low a similar pattern in cells infected with eccentric particles generated by mutations within IN tha

232 Vincent van Gogh (1853-1890) had an eccentric personality and unstable moods, suffered from

233 Eccentric photorefraction was used to record accommodati

234 A remote eccentric photorefractor was used to record accommodativ

235 cteristic of the "athlete's heart," that is, eccentric, physiologic hypertrophy, slower heart rates,

236 We suggest that the eccentric position of the vesicle reflects the polarity

237 ter of the dilated pupil, as well as in four eccentric positions (approximately 3 mm from the center)

238 esponded maximally to ILD cues favoring more eccentric positions in the contralateral sound hemifield

239 t eyes are held steady in straight-ahead and eccentric positions of gaze.

240 n which the head could not be held steady in eccentric positions on the trunk.

241 ics during smooth-pursuit eye movements from eccentric positions.

242 images were obtained at the fovea and at the eccentric preferred retinal locus (PRL).

243 Seventeen eyes had an eccentric PRL associated with a retinal area with no def

244 abecular meshwork, iris hypoplasia, severely eccentric pupils and displaced Schwalbe's line.

245 tously when subjects judge heading around an eccentric reference.

246 This relative hypertrophy was eccentric (relative wall thickness ratios: 0.30+/-0.01 v

247 Concentric and eccentric remodeled anatomies resulted in %dT values of

248 0.35 mm Hg; P=0.009), and lower incidence of eccentric remodeling (12% versus 48%; P=0.03).

249 a(2+) release and pressure overload promoted eccentric remodeling and HF death in RyR2(R4496C+/-) mic

250 as an increase in FFM was associated with LV eccentric remodeling and improved systolic and diastolic

251 overexpression of DUSP8 produced spontaneous eccentric remodeling and ventricular dilation with heart

252 entricle responds to endurance training with eccentric remodeling at all levels of training.

253 to exercise with initial concentric but not eccentric remodeling during the first 6 to 9 months afte

254 isons of the concentric remodeling group and eccentric remodeling group against the control group.

255 nd heart failure (rapid pacing, LBBB+HF, and eccentric remodeling).

256 d (aortic banding), TG hearts developed more eccentric remodeling, maladaptive molecular signaling, d

257 For the advanced phases, the role of eccentric remodeling, vasa vasorum neovascularization, a

258 er body subcutaneous fat was associated with eccentric remodeling.

259 c retinal scotomas than more intact, equally eccentric retina (P = 0.9) CONCLUSIONS: These quantitati

260 On IVUS, various endoluminal defects (eccentric ridges; fluttering membranes; spiraling folds)

261 mice survived to adulthood with spontaneous eccentric right ventricle hypertrophy.

262 process may explain the presence of multiple eccentric rings of young stars in the presence of a supe

263 presence of young massive stars orbiting on eccentric rings within a few tenths of a parsec of the s

264 ability that organizes the dust into narrow, eccentric rings, similar to the Fomalhaut debris disk.

265 hat maturation of the parafoveal (10 degrees eccentric) rod outer segments and visual sensitivity is

266 uisitions, and differences in values between eccentric scans and the central scan were analyzed.

267 Using eccentric SD-OCT acquisition, the boundaries between the

268 Myofiber damage induced by eccentric strain increased with age, reflecting the accu

269 By contrast, eccentric strain induced by long-term running in a wheel

270 eakened ability to produce maximal voluntary eccentric strength.

271 adily control submaximal force; and impaired eccentric strength.

272 Special attention was paid to eccentric strength.

273 abnormalities and improved the resistance to eccentric stress in the mouse model.

274 nder various pathological conditions such as eccentric stretch, osmotic changes during ischaemia and

275 ed four sets of seven maximal concentric and eccentric supine squats 2-3 days per week (every third d

276 relativistic periastron advance for the two eccentric systems indicates that at least one of these p

277 ic stenosis (n = 5), and was associated with eccentric systolic flow jets in all cases.

278 the head is held still when turned toward an eccentric target.

279 heral region that helps generate saccades to eccentric targets and a central one that maintains fixat

280 Saccadic eye movements "bring" eccentric targets to the direct sight line for closer sc

281 No difference was found for the eccentric targets.

282 both in amplitude and area dimension for the eccentric task.

283 e physiological blind spot than over equally eccentric temporal retina (P < 0.05).

284 pot at the optic nerve head and over equally eccentric temporal retina.

285 and those with glaucoma, at both central and eccentric test locations.

286 lbow flexor muscle activity was lower during eccentric than concentric movements, MRCP-indicated cort

287 ter and occurs earlier for controlling human eccentric than concentric submaximal muscle contractions

288 s were more extraverted, open, neurotic, and eccentric than females, whereas females were more agreea

289 mis-localised auditory stimuli as being more eccentric than they were, and did so more when auditory

290 Eccentric to an annular region with no discernible ONL,

291 associated with a type 3 neovascularization eccentric to PEVAC.

292 Features of retinal remodeling were present eccentric to the region of detectable photoreceptors.

293 d IIx fibre enlargements were greatest after eccentric training.

294 The signaling pathways that control eccentric versus concentric heart growth are not well un

295 training modules were: Visual Awareness and Eccentric Viewing (module 1), Control of Reading Eye Mov

296 ction and homework on the use of LV devices, eccentric viewing, and environmental modification.

297 Here we present evidence that observed eccentric warm Jupiters with eccentric giant companions

298 5.1+/-1.2), plaque topography (concentric or eccentric) was determined, and total vessel area, lumen

299 ted 10(o) (parafoveal) or 30(o) (peripheral) eccentric were measured in the dark and in the presence

300 Additionally, eccentric work was increased in the MI hearts.