ライフサイエンスコーパス: ecdysis

1 at prevented entry into cells also prevented ecdysis.

2 t peptide eclosion hormone (EH) before pupal ecdysis.

3 sis I, while ETH activates preecdysis II and ecdysis.

4 of EcR-B1 that is evident at 3 d after pupal ecdysis.

5 d it to investigate the role of EH in larval ecdysis.

6 H has a significant but nonessential role in ecdysis.

7 reactivity decreases centrally during normal ecdysis.

8 on hormone (EH) is a key regulator of insect ecdysis.

9 R, although none showed increases in cGMP at ecdysis.

10 eecdysis within 2 to 10 minutes, followed by ecdysis.

11 ting corresponding to in vivo preecdysis and ecdysis.

12 ile directly expressing the motor program of ecdysis.

13 functions of CCAP and bursicon in Drosophila ecdysis.

14 for the function of CCAP efferent neurons in ecdysis.

15 rogression and results in a failure of pupal ecdysis.

16 val life with trace amounts seen just before ecdysis.

17 ior cuticle and is shed in the cuticle after ecdysis.

18 ht time to degrade the cuticle to facilitate ecdysis.

19 protease gene, nas-37, that cause incomplete ecdysis.

20 regulate hatching, larval growth, and larval ecdysis.

21 in the execution and circadian regulation of ecdysis.

22 ions that are degraded prior to shedding and ecdysis.

23 al weight larvae [5 hours after third instar ecdysis (AL3E)] fed on sucrose alone showed suppressed W

24 e neurons did not show detectable cGMP-IR at ecdysis, although the neurons were CCAP-IR.

25 The molt culminates in ecdysis, an ordered sequence of behaviors that causes th

26 ned-up, which is characterized by incomplete ecdysis and 98% mortality at the transition from first t

27 lure to complete larval-pupal or pupal-adult ecdysis and abnormal wing development are among the most

28 the failure of pupal ecdysis, whereas larval ecdysis and adult eclosion behaviors showed only subtle

29 licit the first two motor behaviors, the pre-ecdysis and ecdysis behaviors, respectively.

30 resulted in the sequential appearance of pre-ecdysis and ecdysis motor outputs.

31 Effects on the execution of ecdysis and its circadian regulation indicate that CCAP

32 injected Mas-ETH appears much earlier before ecdysis and occurs with shorter latency than that report

33 tants in CCAP express no apparent defects in ecdysis and postecdysis, producing normal adults.

34 are the polymerization of melanin during the ecdysis and the change in the layer spacing during the s

35 aried with respect to their cGMP response at ecdysis and their CCAP-IR.

36 e expression of only EcR-A just before pupal ecdysis and then with the expression of low levels of bo

37 c enzyme degrading cuticular proteins before ecdysis and/or indirectly by processing other proteins s

38 increases in cGMP immunoreactivity (-IR) at ecdysis, and all were immunopositive for crustacean card

39 vior consisting of three steps: pre-ecdysis, ecdysis, and postecdysis.

40 P/MIP neurons are active prior to and during ecdysis; and activity of CCAP/MIP/bursicon neurons coinc

41 nce, and immunohistochemical staining during ecdysis, at which time Mas-ETH is found in the hemolymph

42 Ecdysis behavior allows insects to shed their old exoske

43 hort of Ap-let interneurons regulates larval ecdysis behavior by secretion of an unidentified amidate

44 important and heretofore undescribed role in ecdysis behavior itself.

45 key targets of ETH and control the onset of ecdysis behavior, depends fundamentally on the actions o

46 Here, we focus on the endocrine control ecdysis behavior, which is used by arthropods to shed th

47 ir old cuticle by performing the stereotyped ecdysis behavior.

48 t in the central nervous system to evoke the ecdysis behavioral sequence, a stereotype behavior durin

49 atory system on schedule, do not perform the ecdysis behavioral sequence, and exhibit the phenotype b

50 of corazonin signaling in initiation of the ecdysis behavioral sequence.

51 as well as its importance in the control of ecdysis behaviors may change during the postembryonic de

52 aracterized by double mouthparts, absence of ecdysis behaviors, and failure to shed the old cuticle.

53 rst two motor behaviors, the pre-ecdysis and ecdysis behaviors, respectively.

54 the old cuticle by performing preecdysis and ecdysis behaviors.

55 discussed in terms of their highly modified ecdysis behaviors.

56 ells, which induce precocious preecdysis and ecdysis behaviors.

57 ntribute to the mechanisms underlying insect ecdysis behaviors.

58 ide (CCAP), which is involved in stereotyped ecdysis behaviour.

59 We also report a mechanism of insect ecdysis between the first- and second-instar larva, whil

60 CCAP exposure also actively terminated pre-ecdysis bursts from the abdominal CNS, even in the conti

61 In our experiments, the ETH-induced onset of ecdysis bursts was always associated with a rise in intr

62 a responded to CCAP by generating rhythmical ecdysis bursts.

63 resulted in the generation of sustained pre-ecdysis bursts.

64 iter begins to decline and again just before ecdysis, but in the developing adult wings is expressed

65 etwork is remodeled immediately before pupal ecdysis by the emergence of 12 late CCAP neurons.

66 -C was first detected earlier 1.5 days after ecdysis, coincident with the pupal commitment of the win

67 , and DLGR2 transcripts are increased before ecdysis, consistent with their role in postecdysial cuti

68 lease could not be detected, the lack of pre-ecdysis could not be rescued by injections of ETH, sugge

69 involved in controlling growth, development, ecdysis, digestion, diuresis, and many more physiologica

70 expressed in hypodermal cells 4 hours before ecdysis during all larval stages.

71 nate behavior consisting of three steps: pre-ecdysis, ecdysis, and postecdysis.

72 , FMRFamide neurons are activated during pre-ecdysis; EH, CCAP, and CCAP/MIP neurons are active prior

73 o be entirely sufficient for wild-type pupal ecdysis, even after targeted ablation of all other 42 CC

74 the cuticle between larval stages, and pupal ecdysis externalizes and expands the head and appendages

75 network that directs the essential behavior, ecdysis, generates a distinct behavioral sequence at eac

76 Ecdysis (i.e., the shedding of the exoskeleton) in insec

77 or viability through its regulation of pupal ecdysis in a type II receptor Wishful thinking (Wit)-dep

78 Molting and ecdysis in vitro required entry of the parasite into cel

79 role in the Drosophila CNS in the control of ecdysis, in addition to its known role in the periphery

80 ons that produce neuropeptides implicated in ecdysis, including Eclosion hormone (EH), Crustacean car

81 n placed upstream of CCAP, may also regulate ecdysis independently of CCAP.

82 Insect ecdysis is a hormonally programmed physiological sequenc

83 In the month, Manduca sexta, larval ecdysis is accompanied by increases in intracellular cyc

84 Crustacean ecdysis is controlled by at least three neuropeptides: m

85 Ecdysis is triggered by ETH (Ecdysis triggering hormone)

86 sects at the end of a molt (a process called ecdysis) is typically followed by the expansion and tann

87 This sequence, which mediates pupal ecdysis, is governed by the serial release of several ke

88 These ecdysis motor bursts persisted as long as CCAP was prese

89 the sequential appearance of pre-ecdysis and ecdysis motor outputs.

90 P and MIPs, whose joint actions initiate the ecdysis motor program.

91 P) plays a key role in the initiation of the ecdysis motor program.

92 an cardioactive peptide (CCAP) activates the ecdysis motor program; the hormone bursicon is believed

93 The results suggest that ecdysis (moulting) arose once and support the idea of a

94 a stereotypic behavioral sequence leading to ecdysis of the old cuticle.

95 opeptide-mediated developmental transitions (ecdysis or wing expansion) when crossed to the panneurop

96 Despite more than 40 years of research on ecdysis, our understanding of the precise roles of these

97 mmed cell death (PCD) 24 to 48 h after pupal ecdysis (PE).

98 nt six [APR(6)s] die by 48 hours after pupal ecdysis (PE; entry into the pupal stage), whereas APR(4)

99 deficient in PC2 revealed an abnormal larval ecdysis phenotype.

100 dysis; their targeted ablation alters larval ecdysis progression and results in a failure of pupal ec

101 N(CCAP) mediates environmentally insensitive ecdysis-related behaviors in Drosophila development befo

102 Both the timing of ecdysis relative to the molt and the actual execution of

103 s of these signaling molecules in regulating ecdysis remain unclear.

104 Larval ecdysis replaces the cuticle between larval stages, and

105 nimals invariably died at around the time of ecdysis, revealing an essential role in its control.

106 cts shed their old cuticle by performing the ecdysis sequence, an innate behavior consisting of three

107 ach developmental stage, insects perform the ecdysis sequence, an innate behavior necessary for shedd

108 o elucidate neural substrates underlying the ecdysis sequence, we identified neurons expressing ETH r

109 nal in insects through its regulation of the ecdysis sequence.

110 products in initiation and regulation of the ecdysis sequence.

111 layers of the network controlling the pupal ecdysis sequence: a modular input layer, an intermediate

112 f a new insect peptide hormone that triggers ecdysis - shedding of an old cuticle - has revealed hidd

113 nd bursicon show much more severe defects at ecdysis than do animals null for either neuropeptide alo

114 Every molt culminates in ecdysis, the shedding of the remains of the old cuticle.

115 ptide hormones they secrete are critical for ecdysis; their targeted ablation alters larval ecdysis p

116 le by means of a stereotyped behavior called ecdysis, thought to be initiated by the brain peptide ec

117 may be an immediate blood-borne trigger for ecdysis through a direct action on the nervous system.

118 this cGMP response has been associated with ecdysis throughout most of insect evolution.

119 ETH1 restores all deficits and allows normal ecdysis to occur.

120 g discs, the BRC RNAs appeared shortly after ecdysis to the fifth instar and coincided with the onset

121 interactions among several peptide hormones: ecdysis triggering hormone (ETH), eclosion hormone (EH),

122 This sequence is activated by Ecdysis triggering hormone (ETH), which acts on the CNS

123 activating hormone (PK2/PBAN); PKr-C, and 4) ecdysis triggering hormone (ETH); ETHr-b.

124 Ecdysis is triggered by ETH (Ecdysis triggering hormone), and we show that the respon

125 amide), Cap2b-like peptides (-FPRXamide), or ecdysis triggering hormones (-PRXamide).

126 Ecdysis triggering hormones (ETHs) initiate these behavi

127 tence in endocrine Inka cells, the source of ecdysis triggering hormones (ETHs).

128 Blood-borne ecdysis-triggering hormone (ETH) activates the behaviora

129 stem of Manduca sexta show that the peptides ecdysis-triggering hormone (ETH) and crustacean cardioac

130 Ecdysis-triggering hormone (ETH) is essential for courts

131 While ecdysis-triggering hormone (ETH) is sufficient to trigge

132 ated in thoracic ganglia of larvae expresses ecdysis-triggering hormone (ETH) receptors, suggesting t

133 Ecdysis-triggering hormone (ETH) was originally discover

134 ing preecdysis-triggering hormone (PETH) and ecdysis-triggering hormone (ETH), which activate these b

135 orazonin (25-100 pM) induces preecdysis- and ecdysis-triggering hormone secretion.

136 Here an ecdysis-triggering hormone, Mas-ETH, is described from t

137 coordinated eclosion and an insensitivity to ecdysis-triggering hormone.

138 ecdysis, which are initiated upon release of ecdysis-triggering hormones (ETH) into the bloodstream,

139 tracheal glands (EGs) secrete preecdysis and ecdysis-triggering hormones (PETH and ETH) at the end of

140 and CG5911b) that respond preferentially to ecdysis-triggering hormones of flies and moths.

141 ne Inka cells, the source of preecdysis- and ecdysis-triggering hormones.

142 , including the periods preceding and during ecdysis when genetic analysis suggests that pqn-47 funct

143 at the pupal stage from the failure of pupal ecdysis, whereas larval ecdysis and adult eclosion behav

144 derstanding the neuroendocrine regulation of ecdysis, which appears to be largely conserved across in

145 The immediate events leading to ecdysis, which are initiated upon release of ecdysis-tri

146 d to express the preparatory behavior of pre-ecdysis while directly expressing the motor program of e

147 ursicon gene (pburs)] show severe defects in ecdysis, with escaper adults exhibiting the expected fai

148 CCAP KO animals showed specific defects at ecdysis, yet the severity and nature of the defects vari