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1 ther nuclear receptors, including the insect ecdysone receptor.
2 eracts with Ultraspiracle (Usp), part of the ecdysone receptor.
3 the EcR subunit of the heterodimeric EcR-USP ecdysone receptor.
4 e that it is efficiently bound by the Sciara ecdysone receptor.
5 also enhance dominant-negative mutations in ecdysone receptor.
6 n of p75(NTR) is inducibly controlled by the ecdysone receptor.
7 ement (E/GRE) enhancer for binding activated ecdysone receptors.
8 a 3.8-fold increase in TPMT activity in the ecdysone receptor 293 embryonic kidney cell line, we dem
9 r analysis implicated ecdysone signaling via ecdysone receptors A/B1 and the nuclear receptor ftz-f1
10 ne 20-hydroxyecdysone (ecdysone) through the ecdysone receptor, a heterodimer of the nuclear receptor
11 y the steroid hormone 20-OH ecdysone via the ecdysone receptor, a member of the nuclear receptor supe
12 this event, we cloned and characterized the ecdysone receptor (AaEcR) and the nuclear receptor Ultra
14 servations indicate that usp is required for ecdysone receptor activity in vivo, demonstrate that the
15 x (Hsp90 and Hsc70) are required in vivo for ecdysone receptor activity, and that EcR is the primary
16 ild-type and mutant MB neurons in which EcR (ecdysone receptor) activity is genetically blocked, and
17 ents represent in vivo binding sites for the ecdysone receptor and are necessary for hormone-mediated
18 ushroom body (MB), are decommissioned by the ecdysone receptor and mediator complex, causing them to
19 reporter of transcriptional activity of the Ecdysone Receptor and of the Z1 isoform of the Broad Com
20 rogen receptor ligand binding domains or one ecdysone receptor and one retinoid X receptor ligand bin
21 d binding domains of the Heliothis virescens ecdysone receptor and the transactivation domain of the
23 ne-tolerant protein) and ecdysteroid action (ecdysone receptor and ultraspiracle) suggest that these
25 interfering with ecdysone signaling using an ecdysone receptor antagonist or knocking down the ecdyso
26 ns of ecdysone signal transduction involving ecdysone receptor-B (EcR-B) isoforms suppressed vCrz dea
30 x composed of USP (ultraspiracle) and EcRB1 (ecdysone receptor B1) to regulate gene expression in MB
32 axon pruning by regulating the expression of Ecdysone Receptor-B1, a key initiator of axon pruning.
34 ific isoform of the steroid hormone receptor ecdysone receptor-B2, for which functions have thus far
35 abscisic acid (ABA) biosynthesis, using the ecdysone receptor-based plant gene switch system and the
38 traspiracle (USP), the two components of the ecdysone receptor, causes precocious differentiation of
39 We have developed a Choristoneura fumiferana ecdysone receptor (CfEcR)-based two-hybrid gene switch t
43 orphosis in insects by signaling through the ecdysone receptor complex, a heterodimer of the ecdysone
45 we show that rpr is induced directly by the ecdysone-receptor complex through an essential response
48 led that, unlike the Drosophila melanogaster ecdysone receptor (DE), treatment of BE with the ecdyson
49 ssion after mating is induced by 20E via the Ecdysone Receptor, demonstrating a close cooperation bet
50 C1(-/-) clones exhibit reduced levels of the ecdysone receptor EcR-B1, a key regulator of axon prunin
51 ecdysteroid levels induce expression of the ecdysone receptor (EcR) and ETH gene in Inka cells and e
52 sone consists of two nuclear receptors (NRs) ecdysone receptor (EcR) and ultraspiracle (USP), USP bei
55 ts conserved heterodimeric nuclear receptor: Ecdysone Receptor (EcR) and Ultraspiracle (USP)/Retinoid
56 ulation of Notch signaling and activation of ecdysone receptor (EcR) are required for the E/A switch
60 ogous to the acetylcholinesterase (AChE) and ecdysone receptor (EcR) genes of B. tabaci, resulted in
63 oids acting through multiple isoforms of the ecdysone receptor (EcR) initiate molting and metamorphos
65 erexpressing a dominant negative form of the Ecdysone receptor (EcR) or its heterodimeric partner ult
66 receptor coactivator (SRC) and GATAa but not ecdysone receptor (EcR) or its partner, ultraspiracle (U
69 n Orthodenticle (Otd) acts together with the ecdysone receptor (EcR) to directly repress the expressi
70 ltraspiracle (USP), heterodimerizes with the ecdysone receptor (EcR) to form a functional complex tha
71 l patterning of the A and B1 isoforms of the ecdysone receptor (EcR) within muscle DEO1 corresponds w
72 ng this tool, we show that signaling via the Ecdysone Receptor (EcR), a known regulator of developmen
75 notion that USP forms a heterodimer with the ecdysone receptor (EcR), we found that the EcR-B1 isofor
76 ugh a ligand-activated nuclear receptor, the ecdysone receptor (EcR), which plays critical roles in i
79 B) defects and Df(4)dCORL larvae are lacking Ecdysone Receptor (EcR-B1) expression in MB neurons.
83 ke 20-hydroxyecdysone (natural ligand of the ecdysone receptor, EcR), methyl farnesoate, pyrirproxyfe
84 clear receptor heterodimer consisting of the ecdysone receptor, EcR, and the Drosophila RXR receptor,
87 s that are heterozygous for mutations of the ecdysone receptor exhibit increases in life-span and res
90 betaFtz-F1 and a p160/SRC coactivator of the ecdysone receptor, FISC, is crucial for the stage-specif
92 Expression of dsRNA corresponding to the EcR ecdysone receptor gene generated defects in larval molti
93 nown ecdysteroid receptors, we show that the Ecdysone receptor gene is not required for furrow functi
94 one receptor antagonist or knocking down the ecdysone receptor gene with RNAi resulted in an increase
98 E93 transition by inducing expression of the Ecdysone receptor in mid-larval neuroblasts, rendering t
100 and conditional overexpression of wild-type ecdysone receptors in the adult mushroom bodies resulted
103 ronal remodeling and suggest that functional ecdysone receptor is necessary for some, but not all, re
104 We find that ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomous
105 tors that differ according to which of three ecdysone receptor isoforms encoded by the EcR gene (EcR-
106 insect steroid hormone ecdysone to distinct ecdysone receptor isoforms induces different metamorphic
107 sponsive genes, including those encoding the ecdysone receptor itself, a downstream transcription fac
108 DNA amplification in Sciara and suggest the ecdysone receptor may be the elusive amplification facto
109 r expression is neither dependent on the EcR ecdysone receptor nor inducible by ecdysone in cultured
110 taFtz-F1 facilitates loading of FISC and the ecdysone receptor on the target promoters, leading to en
112 vitro studies have demonstrated that the EcR ecdysone receptor requires an RXR heterodimer partner fo
113 ng region was found to contain four putative ecdysone receptor response elements (EcREs) and a monome
116 of both the E/GRE hairpin of the adapter and ecdysone receptors, suggesting it was due to an intrinsi
117 cells by the stable expression of a modified ecdysone receptor that regulates an optimized ecdysone r
118 ins interact with each other as well as with ecdysone receptor, ultraspiracle, and methoprene-toleran
119 the physical locations of the heterodimeric Ecdysone receptor/Ultraspiracle (ECR/USP) nuclear hormon
120 inds to the nuclear hormone receptor complex Ecdysone Receptor/Ultraspiracle, and is recruited to the
121 Transgenes encoding RXRalpha and a chimeric ecdysone receptor under control of a modified MMTV-LTR,
122 ased on a heterodimer composed of a modified ecdysone receptor (VgEcR) and the retinoid X receptor (R
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