ライフサイエンスコーパス: echovirus

1 elated enteroviruses, such as poliovirus and echovirus.

2 mode reported previously for DAF binding to echoviruses.

3 ain dynamics of pathogens such as dengue and echoviruses.

4 uses and coxsackieviruses type B and 94% for echoviruses.

5 85% for coxsackieviruses type B, and 94% for echoviruses.

6 B, and six serotypes of commonly circulating echoviruses.

7 tegrin with antibodies or the human pathogen echovirus 1 (EV1) causes redistribution of alpha2 integr

8 We have examined the mechanism by which echovirus 1 (EV1) enters polarized intestinal epithelial

9 Following analysis in echovirus 1 and collagen binding assays, chimeras with s

10 synthesized and conjugated to enteroviruses echovirus 1 and coxsackievirus B3.

11 Asn(289) had not been implicated in previous echovirus 1 binding studies.

12 Echovirus 1 binding was lost in a chimera containing the

13 ified Asn(289) as playing a critical role in echovirus 1 binding.

14 Binding sites for both collagen and echovirus 1 have been mapped to the I domain within the

15 an also bind to large ligands, such as human echovirus 1.

16 ctions with collagen and is the receptor for echovirus 1.

17 dition, the alpha(2) integrin I domain binds echovirus 1; the alpha(1) I domain does not.

18 oxsackievirus A9; coxsackieviruses B1 to B6; echoviruses 1 to 7, 9, 11 to 21, 24 to 27, and 29 to 33;

19 Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (

20 nfection by diverse enteroviruses, including echovirus 11 (E11), coxsackievirus B (CVB), and enterovi

21 tes, that infection by a DAF-using strain of echovirus 11 (EV11) is dependent upon cholesterol and an

22 By comparison of the binding affinity for echovirus 11 of various fragments of decay-accelerating

23 The interaction between echovirus 11 strain 207 (EV11-207) and decay-acceleratin

24 affinity and kinetics of the interaction of echovirus 11 with its cellular receptor decay-accelerati

25 f infection of polarized epithelial cells by echovirus 11, DAF binding appears be a key determinant i

26 ative IRES element from the Travis strain of echovirus 12 (ECV12), a wild-type, relatively nonvirulen

27 Here, we report a case of echovirus 18-associated severe systemic infection and ac

28 The HPeVs (including the former echoviruses 22 and 23, now HPeV type 1 (HPeV1) and HPeV2

29 ribe a case of acute liver failure caused by echovirus 25 (E25) in a previously healthy 2-year-old bo

30 mers permit specific RT-PCR amplification of echovirus 30 (E30) sequences by targeting sites that enc

31 The most frequent genotypes, echoviruses 6 and 30, were associated with different vir

32 ficiency (1), and liver failure secondary to echovirus 7 (1).

33 Using the echovirus 7 (E7) model in several cell types, we show th

34 s functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and

35 Echovirus 7 (EV7) belongs to the Enterovirus genus withi

36 cryo-electron microscopy reconstructions of echovirus 7 complexed with DAF show that the DAF-binding

37 Echovirus 7 enters polarized Caco-2 intestinal epithelia

38 th specific small interfering RNAs inhibited echovirus 7 infection upstream of uncoating but had litt

39 y characterised mutants of the picornavirus, echovirus 7, in which these parameters were independentl

40 foundly influence the replication ability of echovirus 7.

41 with those observed for the EV-B serotypes, echovirus 9 (E9), E30, and E11, respectively (1.3 to 9.8

42 us clone 2E11 (Chemicon) with 10 poliovirus, echovirus, and coxsackievirus type A and B stock isolate

43 Echoviruses are enteroviruses that belong to Picornaviri

44 an enterovirus species B, which contains the echoviruses, coxsackie B viruses, coxsackievirus A9, and

45 962 isolates revealed 53 NPEV types in which echovirus (E) 6 (7.6%), E14 (7.6%), E11 (7.4%), coxsacki

46 Many serotypes of echovirus (EV) and Coxsackie B virus (CBV) bind human de

47 Echoviruses have been implicated in multiple human disea

48 EV-Bs) (e.g., coxsackie B viruses [CVBs] and echoviruses) have been implicated as environmental facto

49 nal cord, reported identification of a novel echovirus in 15 of 17 French subjects with ALS and only

50 inoculation of newborn transgenic mice with echovirus leads to paralysis and wasting.

51 polioviruses, the coxsackieviruses, and the echoviruses of humans, plus a number of enteroviruses of

52 ate antigen 2 transgenic mice as a model for echovirus pathogenesis.

53 real-time RT-PCR method based on this novel echovirus sequence and used this method and that previou

54 e widely applicable to the identification of echovirus serotypes by PCR.

55 and between adult AGI and enteroviruses when echovirus serotypes predominated.

56 om the binding site of DAF on the surface of echoviruses, suggesting independent evolutionary process

57 reas with a greater similarity to particular echoviruses than to CVB1N, suggesting that recombination

58 cent (3- to 4-week-old) transgenic mice with echovirus type 1 did not lead to paralysis but an acute

59 integrin very late antigen 2, a receptor for echovirus type 1, in transgenic mice conferred susceptib

60 in cells infected with rhinovirus type 16 or echovirus type 1.

61 Echovirus type 12 (EV12), an Enterovirus of the Picornav

62 of the enterovirus isolate identified it as echovirus type 18.

63 for an earlier reconstruction of the related echovirus type 7 bound to DAF, attachment is not within

64 Many echoviruses use decay-accelerating factor (DAF) as their